{"id":"https://openalex.org/W4237138481","doi":"https://doi.org/10.1002/ange.200705300","title":"Organocatalytic Asymmetric Three\u2010Component Cyclization of Cinnamaldehydes and Primary Amines with 1,3\u2010Dicarbonyl Compounds: Straightforward Access to Enantiomerically Enriched Dihydropyridines","display_name":"Organocatalytic Asymmetric Three\u2010Component Cyclization of Cinnamaldehydes and Primary Amines with 1,3\u2010Dicarbonyl Compounds: Straightforward Access to Enantiomerically Enriched Dihydropyridines","publication_year":2008,"publication_date":"2008-02-21","ids":{"openalex":"https://openalex.org/W4237138481","doi":"https://doi.org/10.1002/ange.200705300"},"language":"en","primary_location":{"id":"doi:10.1002/ange.200705300","doi":"https://doi.org/10.1002/ange.200705300","is_oa":false,"landing_page_url":"https://doi.org/10.1002/ange.200705300","pdf_url":null,"source":{"id":"https://openalex.org/S4210200754","display_name":"Angewandte Chemie","issn_l":"0044-8249","issn":["0044-8249","0932-2140","1521-3757"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Angewandte Chemie","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084462717","display_name":"Jun Jiang","orcid":"https://orcid.org/0000-0001-5815-1600","observed_orcids":["https://orcid.org/0000-0001-5815-1600"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210106541","display_name":"Chengdu Organic Chemicals (China)","ror":"https://ror.org/01nmxvn49","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210106541"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jun Jiang","raw_affiliation_strings":["Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences (CAS), Chengdu, 610041, China","Graduate School of the Chinese Academy of Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences (CAS), Chengdu, 610041, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210106541"]},{"raw_affiliation_string":"Graduate School of the Chinese Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084018135","display_name":"Jie Yu","orcid":"https://orcid.org/0000-0002-9968-1429","observed_orcids":["https://orcid.org/0000-0002-9968-1429"]},"institutions":[{"id":"https://openalex.org/I126520041","display_name":"University of Science and Technology of China","ror":"https://ror.org/04c4dkn09","country_code":"CN","type":"education","lineage":["https://openalex.org/I126520041","https://openalex.org/I19820366"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jie Yu","raw_affiliation_strings":["Department of Chemistry, University of Science and Technology of China, Hefei, 230026, China,","Hefei National Laboratory for Physical Sciences at the Microscale","Department of Chemistry, University of Science and Technology of China, Hefei, 230026, China, Fax: (+86) 551-360-6266"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Science and Technology of China, Hefei, 230026, China,","institution_ids":["https://openalex.org/I126520041"]},{"raw_affiliation_string":"Hefei National Laboratory for Physical Sciences at the Microscale","institution_ids":[]},{"raw_affiliation_string":"Department of Chemistry, University of Science and Technology of China, Hefei, 230026, China, Fax: (+86) 551-360-6266","institution_ids":["https://openalex.org/I126520041"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109604834","display_name":"Xixi Sun","orcid":"https://orcid.org/0000-0002-5344-8023","observed_orcids":["https://orcid.org/0000-0002-5344-8023"]},"institutions":[{"id":"https://openalex.org/I126520041","display_name":"University of Science and Technology of China","ror":"https://ror.org/04c4dkn09","country_code":"CN","type":"education","lineage":["https://openalex.org/I126520041","https://openalex.org/I19820366"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xi\u2010Xi Sun","raw_affiliation_strings":["Department of Chemistry, University of Science and Technology of China, Hefei, 230026, China,","Hefei National Laboratory for Physical Sciences at the Microscale","Department of Chemistry, University of Science and Technology of China, Hefei, 230026, China, Fax: (+86) 551-360-6266"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Science and Technology of China, Hefei, 230026, China,","institution_ids":["https://openalex.org/I126520041"]},{"raw_affiliation_string":"Hefei National Laboratory for Physical Sciences at the Microscale","institution_ids":[]},{"raw_affiliation_string":"Department of Chemistry, University of Science and Technology of China, Hefei, 230026, China, Fax: (+86) 551-360-6266","institution_ids":["https://openalex.org/I126520041"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043202046","display_name":"Qin\u2010Quan Rao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126520041","display_name":"University of Science and Technology of China","ror":"https://ror.org/04c4dkn09","country_code":"CN","type":"education","lineage":["https://openalex.org/I126520041","https://openalex.org/I19820366"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qin\u2010Quan Rao","raw_affiliation_strings":["Department of Chemistry, University of Science and Technology of China, Hefei, 230026, China,","Hefei National Laboratory for Physical Sciences at the Microscale","Department of Chemistry, University of Science and Technology of China, Hefei, 230026, China, Fax: (+86) 551-360-6266"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Science and Technology of China, Hefei, 230026, China,","institution_ids":["https://openalex.org/I126520041"]},{"raw_affiliation_string":"Hefei National Laboratory for Physical Sciences at the Microscale","institution_ids":[]},{"raw_affiliation_string":"Department of Chemistry, University of Science and Technology of China, Hefei, 230026, China, Fax: (+86) 551-360-6266","institution_ids":["https://openalex.org/I126520041"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5080902320","display_name":"Liu\u2010Zhu Gong","orcid":"https://orcid.org/0000-0001-6099-827X","observed_orcids":["https://orcid.org/0000-0001-6099-827X"]},"institutions":[{"id":"https://openalex.org/I126520041","display_name":"University of Science and Technology of China","ror":"https://ror.org/04c4dkn09","country_code":"CN","type":"education","lineage":["https://openalex.org/I126520041","https://openalex.org/I19820366"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210106541","display_name":"Chengdu Organic Chemicals (China)","ror":"https://ror.org/01nmxvn49","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210106541"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Liu\u2010Zhu Gong","raw_affiliation_strings":["Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences (CAS), Chengdu, 610041, China","Department of Chemistry, University of Science and Technology of China, Hefei, 230026, China, Fax: (+86) 551-360-6266","Hefei National Laboratory for Physical Sciences at the Microscale"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences (CAS), Chengdu, 610041, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210106541"]},{"raw_affiliation_string":"Department of Chemistry, University of Science and Technology of China, Hefei, 230026, China, Fax: (+86) 551-360-6266","institution_ids":["https://openalex.org/I126520041"]},{"raw_affiliation_string":"Hefei National Laboratory for Physical Sciences at the Microscale","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5080902320"],"corresponding_institution_ids":["https://openalex.org/I126520041","https://openalex.org/I19820366","https://openalex.org/I4210106541"],"apc_list":{"value":5790,"currency":"USD","value_usd":5790},"apc_paid":null,"fwci":3.7644,"has_fulltext":false,"cited_by_count":48,"citation_normalized_percentile":{"value":0.93947276,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":99},"biblio":{"volume":"120","issue":"13","first_page":"2492","last_page":"2496"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10013","display_name":"Asymmetric Synthesis and Catalysis","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10013","display_name":"Asymmetric Synthesis and Catalysis","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10817","display_name":"Multicomponent Synthesis of Heterocycles","score":0.00800000037997961,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11281","display_name":"Asymmetric Hydrogenation and Catalysis","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/1604","display_name":"Inorganic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/organocatalysis","display_name":"organocatalysis","score":0.9129999876022339},{"id":"https://openalex.org/keywords/cinnamaldehyde","display_name":"cinnamaldehyde","score":0.8980000019073486},{"id":"https://openalex.org/keywords/primary-amines","display_name":"primary amines","score":0.9940000176429749},{"id":"https://openalex.org/keywords/1-3-dicarbonyl-compounds","display_name":"1,3-dicarbonyl compounds","score":0.9980000257492065},{"id":"https://openalex.org/keywords/1-4-dihydropyridines","display_name":"1,4-dihydropyridines","score":0.8949999809265137},{"id":"https://openalex.org/keywords/asymmetric-synthesis","display_name":"asymmetric synthesis","score":0.8980000019073486},{"id":"https://openalex.org/keywords/tetrahydropyridines","display_name":"tetrahydropyridines","score":0.9319999814033508},{"id":"https://openalex.org/keywords/piperidine","display_name":"piperidine","score":0.8690000176429749}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7635992765426636},{"id":"https://openalex.org/C2780263894","wikidata":"https://www.wikidata.org/wiki/Q335268","display_name":"Alkyl","level":2,"score":0.5835287570953369},{"id":"https://openalex.org/C2781076698","wikidata":"https://www.wikidata.org/wiki/Q718074","display_name":"Aryl","level":3,"score":0.5202930569648743},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.5063234567642212},{"id":"https://openalex.org/C146686406","wikidata":"https://www.wikidata.org/wiki/Q898628","display_name":"Enantioselective synthesis","level":3,"score":0.43331417441368103},{"id":"https://openalex.org/C2781212610","wikidata":"https://www.wikidata.org/wiki/Q39094","display_name":"Dihydropyridine","level":3,"score":0.4236946105957031},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.2418728768825531},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.13448414206504822},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/ange.200705300","doi":"https://doi.org/10.1002/ange.200705300","is_oa":false,"landing_page_url":"https://doi.org/10.1002/ange.200705300","pdf_url":null,"source":{"id":"https://openalex.org/S4210200754","display_name":"Angewandte Chemie","issn_l":"0044-8249","issn":["0044-8249","0932-2140","1521-3757"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Angewandte Chemie","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":64,"referenced_works":["https://openalex.org/W54812405","https://openalex.org/W1963544878","https://openalex.org/W1968113332","https://openalex.org/W1969900549","https://openalex.org/W1973492721","https://openalex.org/W1980896239","https://openalex.org/W1983341546","https://openalex.org/W1983806218","https://openalex.org/W1991060795","https://openalex.org/W1993127077","https://openalex.org/W1995857257","https://openalex.org/W2005619234","https://openalex.org/W2006467583","https://openalex.org/W2007914640","https://openalex.org/W2010024344","https://openalex.org/W2015283262","https://openalex.org/W2016075951","https://openalex.org/W2017350098","https://openalex.org/W2019041907","https://openalex.org/W2023128292","https://openalex.org/W2023351676","https://openalex.org/W2025828989","https://openalex.org/W2034648400","https://openalex.org/W2036865182","https://openalex.org/W2038371540","https://openalex.org/W2040559769","https://openalex.org/W2045187578","https://openalex.org/W2054995175","https://openalex.org/W2059984461","https://openalex.org/W2069273220","https://openalex.org/W2072420055","https://openalex.org/W2081332060","https://openalex.org/W2082090466","https://openalex.org/W2082916506","https://openalex.org/W2083908919","https://openalex.org/W2095958188","https://openalex.org/W2100845585","https://openalex.org/W2102512629","https://openalex.org/W2104017229","https://openalex.org/W2106763755","https://openalex.org/W2113573800","https://openalex.org/W2114741594","https://openalex.org/W2118180102","https://openalex.org/W2119202267","https://openalex.org/W2120305574","https://openalex.org/W2120780345","https://openalex.org/W2124923400","https://openalex.org/W2143094761","https://openalex.org/W2143395453","https://openalex.org/W2148797658","https://openalex.org/W2153259344","https://openalex.org/W2162961024","https://openalex.org/W2167137322","https://openalex.org/W2168204348","https://openalex.org/W2169174125","https://openalex.org/W2335179795","https://openalex.org/W2951540812","https://openalex.org/W2952490572","https://openalex.org/W2953073526","https://openalex.org/W4211144669","https://openalex.org/W4235627433","https://openalex.org/W4241509219","https://openalex.org/W4244745906","https://openalex.org/W4247284468"],"related_works":["https://openalex.org/W2952306834","https://openalex.org/W2090035791","https://openalex.org/W1987539247","https://openalex.org/W1998333211","https://openalex.org/W4251410434","https://openalex.org/W2173869916","https://openalex.org/W4408666982","https://openalex.org/W4210764034","https://openalex.org/W2151252671","https://openalex.org/W2031553165"],"abstract_inverted_index":{"Aller":[0],"guten":[1],"Dinge":[2],"sind":[3,31],"drei:":[4],"Die":[5,29],"Titelreaktion":[6],"l\u00e4uft":[7],"unter":[8],"milden":[9],"Bedingungen":[10],"in":[11],"Gegenwart":[12],"eines":[13],"chiralen":[14],"Phoshons\u00e4ure-Katalysators":[15],"ab":[16],"und":[17,40,46],"liefert":[18],"4-arylsubstituierte":[19],"1,4-Dihydropyridine":[20],"mit":[21],"bis":[22],"zu":[23],"98":[24],"%":[25],"ee":[26],"(siehe":[27],"Schema).":[28],"Produkte":[30],"n\u00fctzliche":[32],"Substrate":[33],"f\u00fcr":[34],"die":[35],"asymmetrische":[36],"Synthese":[37],"von":[38,44],"Tetrahydropyridinen":[39],"Piperidinen,":[41],"h\u00e4ufigen":[42],"Teilstrukturen":[43],"Naturstoffen":[45],"Arzneimitteln.":[47],"R1=Aryl;":[48],"R2,R3=Alkyl.":[49]},"counts_by_year":[{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":8},{"year":2012,"cited_by_count":2}],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2022-05-12T00:00:00"}