{"id":"https://openalex.org/W4236325405","doi":"https://doi.org/10.1016/j.cell.2016.08.010","title":"Myeloid-Cell-Derived VEGF Maintains Brain Glucose Uptake and Limits Cognitive Impairment in Obesity","display_name":"Myeloid-Cell-Derived VEGF Maintains Brain Glucose Uptake and Limits Cognitive Impairment in Obesity","publication_year":2016,"publication_date":"2016-08-01","ids":{"openalex":"https://openalex.org/W4236325405","doi":"https://doi.org/10.1016/j.cell.2016.08.010"},"language":"en","primary_location":{"id":"doi:10.1016/j.cell.2016.08.010","doi":"https://doi.org/10.1016/j.cell.2016.08.010","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.cell.2016.08.010","pdf_url":"http://www.cell.com/article/S0092867416310595/pdf","source":{"id":"https://openalex.org/S110447773","display_name":"Cell","issn_l":"0092-8674","issn":["0092-8674","1097-4172"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.cell.com/article/S0092867416310595/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075766037","display_name":"Alexander Ja\u00efs","orcid":"https://orcid.org/0000-0002-9897-4983","observed_orcids":["https://orcid.org/0000-0002-9897-4983"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alexander Jais","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085401423","display_name":"Maite Solas","orcid":"https://orcid.org/0000-0001-7670-3237","observed_orcids":["https://orcid.org/0000-0001-7670-3237"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Maite Solas","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038678011","display_name":"Heiko Backes","orcid":"https://orcid.org/0000-0002-0318-1615","observed_orcids":["https://orcid.org/0000-0002-0318-1615"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Heiko Backes","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063897991","display_name":"Bhagirath Chaurasia","orcid":"https://orcid.org/0000-0002-7998-9290","observed_orcids":["https://orcid.org/0000-0002-7998-9290"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bhagirath Chaurasia","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057035695","display_name":"Andr\u00e9 Kleinridders","orcid":"https://orcid.org/0000-0002-4248-6366","observed_orcids":["https://orcid.org/0000-0002-4248-6366"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andr\u00e9 Kleinridders","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039732735","display_name":"Sebastian Theurich","orcid":"https://orcid.org/0000-0001-5706-8258","observed_orcids":["https://orcid.org/0000-0001-5706-8258"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sebastian Theurich","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075873381","display_name":"Jan Mauer","orcid":"https://orcid.org/0000-0002-0189-5876","observed_orcids":["https://orcid.org/0000-0002-0189-5876"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jan Mauer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072170237","display_name":"Sophie Marie Steculorum","orcid":"https://orcid.org/0000-0002-5665-2732","observed_orcids":["https://orcid.org/0000-0002-5665-2732"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sophie M. Steculorum","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058171285","display_name":"Brigitte Hampel","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Brigitte Hampel","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037576579","display_name":"Julia Goldau","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Julia Goldau","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Jens Alber","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jens Alber","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012146217","display_name":"Carola Yvette F\u00f6rster","orcid":"https://orcid.org/0000-0002-3878-247X","observed_orcids":["https://orcid.org/0000-0002-3878-247X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Carola Y. F\u00f6rster","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083476093","display_name":"Sabine Anne Eming","orcid":"https://orcid.org/0000-0001-8485-3921","observed_orcids":["https://orcid.org/0000-0001-8485-3921"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sabine A. Eming","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009423317","display_name":"Markus Schwaninger","orcid":"https://orcid.org/0000-0002-4510-9718","observed_orcids":["https://orcid.org/0000-0002-4510-9718"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Markus Schwaninger","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Napoleone Ferrara","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Napoleone Ferrara","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086824931","display_name":"G\u00e9rard Karsenty","orcid":"https://orcid.org/0000-0002-9253-7627","observed_orcids":["https://orcid.org/0000-0002-9253-7627","https://orcid.org/0000-0002-9047-3332"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gerard Karsenty","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5112420225","display_name":"Jens C. Br\u00fcning","orcid":"https://orcid.org/0000-0002-6619-0092","observed_orcids":["https://orcid.org/0000-0002-6619-0092"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Jens C. Br\u00fcning","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5112420225"],"corresponding_institution_ids":[],"apc_list":{"value":11400,"currency":"USD","value_usd":11400},"apc_paid":null,"fwci":2.5206,"has_fulltext":false,"cited_by_count":47,"citation_normalized_percentile":{"value":0.89251716,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"166","issue":"5","first_page":"1338","last_page":"1340"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11872","display_name":"Barrier Structure and Function Studies","score":0.5419999957084656,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11872","display_name":"Barrier Structure and Function Studies","score":0.5419999957084656,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.35600000619888306,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.04690000042319298,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vascular-endothelial-growth-factor","display_name":"vascular endothelial growth factor","score":0.8360000252723694},{"id":"https://openalex.org/keywords/myeloid-cells","display_name":"myeloid cells","score":0.9629999995231628},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.7490000128746033},{"id":"https://openalex.org/keywords/cerebral-glucose-uptake","display_name":"brain glucose uptake","score":0.9779999852180481},{"id":"https://openalex.org/keywords/cognitive-impairment","display_name":"cognitive impairment","score":0.8759999871253967},{"id":"https://openalex.org/keywords/neuroinflammation","display_name":"neuroinflammation","score":0.8019999861717224},{"id":"https://openalex.org/keywords/perivascular-macrophages","display_name":"perivascular macrophages","score":0.9290000200271606},{"id":"https://openalex.org/keywords/high-fat-diet","display_name":"high-fat diet","score":0.7670000195503235},{"id":"https://openalex.org/keywords/app-ps1-mice","display_name":"APP/PS1 mice","score":0.8769999742507935},{"id":"https://openalex.org/keywords/blood-brain-barrier","display_name":"blood-brain barrier","score":0.7829999923706055},{"id":"https://openalex.org/keywords/glucose-transporters","display_name":"glucose transporters","score":0.9539999961853027},{"id":"https://openalex.org/keywords/neurodegeneration","display_name":"neurodegeneration","score":0.9789999723434448}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6536269187927246},{"id":"https://openalex.org/C87753298","wikidata":"https://www.wikidata.org/wiki/Q17157137","display_name":"Neuroinflammation","level":3,"score":0.626322865486145},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.5101866722106934},{"id":"https://openalex.org/C161573976","wikidata":"https://www.wikidata.org/wiki/Q420277","display_name":"Glucose transporter","level":3,"score":0.500096321105957},{"id":"https://openalex.org/C2776925932","wikidata":"https://www.wikidata.org/wiki/Q1755122","display_name":"Neurodegeneration","level":3,"score":0.4964771866798401},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.45571139454841614},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.45503920316696167},{"id":"https://openalex.org/C127561419","wikidata":"https://www.wikidata.org/wiki/Q224527","display_name":"Downregulation and upregulation","level":3,"score":0.4111286699771881},{"id":"https://openalex.org/C149011108","wikidata":"https://www.wikidata.org/wiki/Q652985","display_name":"Transporter","level":3,"score":0.4106272757053375},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3819322884082794},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2389203906059265},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.2122114896774292},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.19800585508346558},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.1581520140171051},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.15269488096237183},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.1434539556503296},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1391344666481018}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.cell.2016.08.010","doi":"https://doi.org/10.1016/j.cell.2016.08.010","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.cell.2016.08.010","pdf_url":"http://www.cell.com/article/S0092867416310595/pdf","source":{"id":"https://openalex.org/S110447773","display_name":"Cell","issn_l":"0092-8674","issn":["0092-8674","1097-4172"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.cell.2016.08.010","doi":"https://doi.org/10.1016/j.cell.2016.08.010","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.cell.2016.08.010","pdf_url":"http://www.cell.com/article/S0092867416310595/pdf","source":{"id":"https://openalex.org/S110447773","display_name":"Cell","issn_l":"0092-8674","issn":["0092-8674","1097-4172"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W4236325405.pdf"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2346650439","https://openalex.org/W2791999377","https://openalex.org/W2948266976","https://openalex.org/W4324056023","https://openalex.org/W4383482909","https://openalex.org/W2323267661","https://openalex.org/W4398138048","https://openalex.org/W2793103592","https://openalex.org/W43197449","https://openalex.org/W3176720622"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2022-05-12T00:00:00"}