{"id":"https://openalex.org/W4235986379","doi":"https://doi.org/10.1177/117693510700300018","title":"Comparison of Predicted Probabilities of Proportional Hazards Regression and Linear Discriminant Analysis Methods Using a Colorectal Cancer Molecular Biomarker Database","display_name":"Comparison of Predicted Probabilities of Proportional Hazards Regression and Linear Discriminant Analysis Methods Using a Colorectal Cancer Molecular Biomarker Database","publication_year":2007,"publication_date":"2007-01-01","ids":{"openalex":"https://openalex.org/W4235986379","doi":"https://doi.org/10.1177/117693510700300018","pmid":"https://pubmed.ncbi.nlm.nih.gov/19455238","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2675853"},"language":"en","primary_location":{"id":"doi:10.1177/117693510700300018","doi":"https://doi.org/10.1177/117693510700300018","is_oa":true,"landing_page_url":"https://doi.org/10.1177/117693510700300018","pdf_url":"https://journals.sagepub.com/doi/pdf/10.1177/117693510700300018","source":{"id":"https://openalex.org/S55012689","display_name":"Cancer Informatics","issn_l":"1176-9351","issn":["1176-9351"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Informatics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.sagepub.com/doi/pdf/10.1177/117693510700300018","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024420238","display_name":"Sreelatha Meleth","orcid":"https://orcid.org/0000-0001-7149-8262","observed_orcids":["https://orcid.org/0000-0001-7149-8262"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sreelatha Meleth","raw_affiliation_strings":["Biomedical Statistics, Department of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Statistics, Department of Medicine","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079147357","display_name":"Chakrapani Chatla","orcid":"https://orcid.org/0000-0002-3259-0602","observed_orcids":["https://orcid.org/0000-0002-3259-0602"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chakrapani Chatla","raw_affiliation_strings":["Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073586472","display_name":"Venkat Rao Katkoori","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Venkat R. Katkoori","raw_affiliation_strings":["Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020969578","display_name":"Billie S. Anderson","orcid":"https://orcid.org/0000-0002-1327-7004","observed_orcids":["https://orcid.org/0000-0002-1327-7004"]},"institutions":[{"id":"https://openalex.org/I17301866","display_name":"University of Alabama","ror":"https://ror.org/03xrrjk67","country_code":"US","type":"education","lineage":["https://openalex.org/I17301866"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Billie Anderson","raw_affiliation_strings":["Department of Information Systems, Statistics, and Management, University of Alabama at Tuscaloosa, Alabama"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Information Systems, Statistics, and Management, University of Alabama at Tuscaloosa, Alabama","institution_ids":["https://openalex.org/I17301866"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041079631","display_name":"J. Michael Hardin","orcid":"https://orcid.org/0000-0003-4468-0661","observed_orcids":["https://orcid.org/0000-0003-4468-0661"]},"institutions":[{"id":"https://openalex.org/I17301866","display_name":"University of Alabama","ror":"https://ror.org/03xrrjk67","country_code":"US","type":"education","lineage":["https://openalex.org/I17301866"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James M. Hardin","raw_affiliation_strings":["Department of Information Systems, Statistics, and Management, University of Alabama at Tuscaloosa, Alabama"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Information Systems, Statistics, and Management, University of Alabama at Tuscaloosa, Alabama","institution_ids":["https://openalex.org/I17301866"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112695292","display_name":"Nirag Chandrakant Jhala","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nirag C. Jhala","raw_affiliation_strings":["Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109961932","display_name":"Al Bartolucci","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Al Bartolucci","raw_affiliation_strings":["Department of Biostatistics, University of Alabama at Birmingham, AL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, University of Alabama at Birmingham, AL","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076077003","display_name":"William E. Grizzle","orcid":"https://orcid.org/0000-0001-9245-0401","observed_orcids":["https://orcid.org/0000-0001-9245-0401"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William E. Grizzle","raw_affiliation_strings":["Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038817160","display_name":"Upender Manne","orcid":"https://orcid.org/0000-0002-1545-3032","observed_orcids":["https://orcid.org/0000-0002-1545-3032"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Upender Manne","raw_affiliation_strings":["Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama","institution_ids":["https://openalex.org/I32389192"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5038817160"],"corresponding_institution_ids":["https://openalex.org/I32389192"],"apc_list":{"value":2650,"currency":"USD","value_usd":2650},"apc_paid":{"value":2650,"currency":"USD","value_usd":2650},"fwci":0.5988,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.75570894,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"3","issue":null,"first_page":"117693510700300","last_page":"117693510700300"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10136","display_name":"Statistical Methods and Inference","score":0.5580999851226807,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10136","display_name":"Statistical Methods and Inference","score":0.5580999851226807,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.25949999690055847,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.0771000012755394,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/colorectal-cancer","display_name":"colorectal cancer","score":0.9789999723434448},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.8610000014305115},{"id":"https://openalex.org/keywords/cox-proportional-hazards-model","display_name":"Cox proportional hazards model","score":0.8970000147819519},{"id":"https://openalex.org/keywords/linear-discriminant-analysis","display_name":"linear discriminant analysis","score":1.0},{"id":"https://openalex.org/keywords/survival-prediction","display_name":"survival prediction","score":0.7590000033378601},{"id":"https://openalex.org/keywords/p53-expression","display_name":"p53 expression","score":0.9089999794960022},{"id":"https://openalex.org/keywords/bcl-2-expression","display_name":"Bcl-2 expression","score":1.0},{"id":"https://openalex.org/keywords/feature-selection","display_name":"feature selection","score":0.7570000290870667},{"id":"https://openalex.org/keywords/tumor-stage","display_name":"tumor stage","score":0.597000002861023},{"id":"https://openalex.org/keywords/model-prediction-accuracy","display_name":"model prediction accuracy","score":0.3619999885559082},{"id":"https://openalex.org/keywords/molecular-biomarkers","display_name":"molecular biomarkers","score":0.5049999952316284}],"concepts":[{"id":"https://openalex.org/C69738355","wikidata":"https://www.wikidata.org/wiki/Q1228929","display_name":"Linear discriminant analysis","level":2,"score":0.7753635048866272},{"id":"https://openalex.org/C148483581","wikidata":"https://www.wikidata.org/wiki/Q446488","display_name":"Feature selection","level":2,"score":0.6209148168563843},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.582363486289978},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.484650194644928},{"id":"https://openalex.org/C169903167","wikidata":"https://www.wikidata.org/wiki/Q3985153","display_name":"Test set","level":2,"score":0.48152193427085876},{"id":"https://openalex.org/C152877465","wikidata":"https://www.wikidata.org/wiki/Q208042","display_name":"Regression analysis","level":2,"score":0.45452064275741577},{"id":"https://openalex.org/C163175372","wikidata":"https://www.wikidata.org/wiki/Q3339222","display_name":"Linear model","level":2,"score":0.4327274262905121},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.42274293303489685},{"id":"https://openalex.org/C203868755","wikidata":"https://www.wikidata.org/wiki/Q5353562","display_name":"Elastic net regularization","level":3,"score":0.4158414304256439},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4113842844963074},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.34962838888168335},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.30164164304733276},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.278302401304245},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.23200839757919312},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1887257695198059}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1177/117693510700300018","doi":"https://doi.org/10.1177/117693510700300018","is_oa":true,"landing_page_url":"https://doi.org/10.1177/117693510700300018","pdf_url":"https://journals.sagepub.com/doi/pdf/10.1177/117693510700300018","source":{"id":"https://openalex.org/S55012689","display_name":"Cancer Informatics","issn_l":"1176-9351","issn":["1176-9351"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Informatics","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2675853","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2675853","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Inform","raw_type":"Text"},{"id":"pmid:19455238","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19455238","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer informatics","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:67bb0ab9519448c89a966a02364dfda4","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/67bb0ab9519448c89a966a02364dfda4","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cancer Informatics, Vol 3 (2007)","raw_type":"article"},{"id":"pmh:oai:doaj.org/article:8318a2281e764bf786fe7bf8d21e951a","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/8318a2281e764bf786fe7bf8d21e951a","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cancer Informatics, Vol 3, Pp 115-122 (2007)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1177/117693510700300018","doi":"https://doi.org/10.1177/117693510700300018","is_oa":true,"landing_page_url":"https://doi.org/10.1177/117693510700300018","pdf_url":"https://journals.sagepub.com/doi/pdf/10.1177/117693510700300018","source":{"id":"https://openalex.org/S55012689","display_name":"Cancer Informatics","issn_l":"1176-9351","issn":["1176-9351"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Informatics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G74575479","display_name":"Biomarker Reference Laboratory, EDRN","funder_award_id":"5u24ca086359-09","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8707641428","display_name":"Prognostic Molecular Markers of Colorectal Cancer","funder_award_id":"R01CA098932","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4235986379.pdf"},"referenced_works_count":17,"referenced_works":["https://openalex.org/W628441875","https://openalex.org/W1575982426","https://openalex.org/W1587213099","https://openalex.org/W1967091595","https://openalex.org/W1977531766","https://openalex.org/W1984903284","https://openalex.org/W2057621760","https://openalex.org/W2078005904","https://openalex.org/W2117114376","https://openalex.org/W2158922990","https://openalex.org/W2486548726","https://openalex.org/W2598363796","https://openalex.org/W2885038346","https://openalex.org/W2994296171","https://openalex.org/W3126984856","https://openalex.org/W4235730193","https://openalex.org/W4243533591"],"related_works":["https://openalex.org/W3142939358","https://openalex.org/W2063893072","https://openalex.org/W1951342611","https://openalex.org/W1963571165","https://openalex.org/W3152915158","https://openalex.org/W4385717014","https://openalex.org/W2791652737","https://openalex.org/W4402747843","https://openalex.org/W7052150651","https://openalex.org/W1530087864"],"abstract_inverted_index":{"BACKGROUND:":[0],"Although":[1],"a":[2,23,55,61,82,229,239,264,269],"majority":[3],"of":[4,22,42,52,60,90,98,122,141,151,174,182,192,218,259,274],"studies":[5,29],"in":[6,66,124,144,153,164,171,190,256],"cancer":[7,85],"biomarker":[8,24],"discovery":[9],"claim":[10],"to":[11,17,25,38,58,115,137,214,245],"use":[12,30],"proportional":[13],"hazards":[14],"regression":[15,135],"(PHREG)":[16],"the":[18,20,31,36,40,43,50,110,117,139,145,149,154,172,180,200,203,207,221,257,260],"study":[19,226,253],"ability":[21],"predict":[26],"survival,":[27],"few":[28],"predicted":[32],"probabilities":[33],"obtained":[34],"from":[35,199],"model":[37,57,136,209,231],"test":[39,70,155],"quality":[41,51],"model.":[44,223],"In":[45],"this":[46,252],"paper,":[47],"we":[48],"compared":[49,213],"predictions":[53],"by":[54],"PHREG":[56,75,222,230],"that":[59,228,255],"linear":[62,134],"discriminant":[63,107],"analysis":[64,108],"(LDA)":[65],"both":[67,191],"training":[68,146],"and":[69,76,92,95,100,109,184],"set":[71,147],"settings.":[72],"METHODS:":[73],"The":[74,120,158],"LDA":[77,208,244],"models":[78,126,166],"were":[79,113],"built":[80],"on":[81,148],"491":[83],"colorectal":[84],"(CRC)":[86],"patient":[87],"dataset":[88],"comprised":[89],"demographic":[91],"clinicopathologic":[93],"variables,":[94],"phenotypic":[96],"expression":[97,267],"p53":[99],"Bcl-2.":[101],"Two":[102],"variable":[103,160,201],"selection":[104,161],"methods,":[105],"stepwise":[106],"backward":[111],"selection,":[112],"used":[114,133],"identify":[116],"final":[118],"models.":[119,194],"endpoint":[121],"prediction":[123,152],"these":[125,193],"was":[127,169,188,197,210],"five-year":[128],"post-surgery":[129],"survival.":[130],"We":[131],"also":[132],"examine":[138],"effect":[140],"bin":[142],"size":[143],"accuracy":[150],"set.":[156],"RESULTS:":[157],"two":[159],"techniques":[162],"resulted":[163],"different":[165],"when":[167],"stage":[168,196,262],"included":[170],"list":[173],"variables":[175],"available":[176],"for":[177,206,220],"selection.":[178],"However,":[179],"proportion":[181],"survivors":[183],"non-survivors":[185],"correctly":[186],"identified":[187],"identical":[189],"When":[195],"excluded":[198],"list,":[202],"error":[204,216],"rate":[205,217],"42%":[211],"as":[212,234,243,263],"an":[215],"34%":[219],"CONCLUSIONS:":[224],"This":[225],"suggests":[227,254],"can":[232],"perform":[233],"well":[235],"or":[236],"better":[237],"than":[238],"traditional":[240],"classifier":[241],"such":[242],"classify":[246],"patients":[247],"into":[248],"prognostic":[249,271],"classes.":[250],"Also,":[251],"absence":[258],"tumor":[261],"variable,":[265],"Bcl-2":[266],"is":[268],"strong":[270],"molecular":[272],"marker":[273],"CRC.":[275]},"counts_by_year":[{"year":2017,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2022-05-12T00:00:00"}