{"id":"https://openalex.org/W4235898635","doi":"https://doi.org/10.1083/jcb1886oia14","title":"Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3\u03b2 phosphorylation","display_name":"Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3\u03b2 phosphorylation","publication_year":2010,"publication_date":"2010-03-22","ids":{"openalex":"https://openalex.org/W4235898635","doi":"https://doi.org/10.1083/jcb1886oia14"},"language":"en","primary_location":{"id":"doi:10.1083/jcb1886oia14","doi":"https://doi.org/10.1083/jcb1886oia14","is_oa":false,"landing_page_url":"https://doi.org/10.1083/jcb1886oia14","pdf_url":null,"source":{"id":"https://openalex.org/S96410829","display_name":"The Journal of Cell Biology","issn_l":"0021-9525","issn":["0021-9525","1540-8140"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Cell Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034138320","display_name":"Zhongshu Tang","orcid":"https://orcid.org/0000-0001-6202-7637","observed_orcids":["https://orcid.org/0000-0001-6202-7637"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zhongshu Tang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052825588","display_name":"Pachiappan Arjunan","orcid":"https://orcid.org/0000-0001-9470-1171","observed_orcids":["https://orcid.org/0000-0001-9470-1171"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Pachiappan Arjunan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009746691","display_name":"Chunsik Lee","orcid":"https://orcid.org/0000-0002-8151-7196","observed_orcids":["https://orcid.org/0000-0002-8151-7196"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chunsik Lee","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100421649","display_name":"Yang Li","orcid":"https://orcid.org/0000-0002-8734-4054","observed_orcids":["https://orcid.org/0000-0002-8734-4054"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yang Li","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100714238","display_name":"Anil Kumar","orcid":"https://orcid.org/0000-0001-6813-7765","observed_orcids":["https://orcid.org/0000-0001-6813-7765"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anil Kumar","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100409280","display_name":"Xu Hou","orcid":"https://orcid.org/0000-0002-2781-7219","observed_orcids":["https://orcid.org/0000-0002-2781-7219","https://orcid.org/0000-0002-4574-4359"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xu Hou","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100372377","display_name":"Bin Wang","orcid":"https://orcid.org/0000-0002-6159-5242","observed_orcids":["https://orcid.org/0000-0002-6159-5242"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bin Wang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043204762","display_name":"Piotr Ward\u0119ga","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Piotr Wardega","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100403517","display_name":"Fan Zhang","orcid":"https://orcid.org/0000-0002-8813-2627","observed_orcids":["https://orcid.org/0000-0002-8813-2627"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fan Zhang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083119433","display_name":"Lijin Dong","orcid":"https://orcid.org/0000-0001-7401-9511","observed_orcids":["https://orcid.org/0000-0001-7401-9511"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lijin Dong","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100741915","display_name":"Yongqing Zhang","orcid":"https://orcid.org/0000-0003-0581-4882","observed_orcids":["https://orcid.org/0000-0003-0581-4882","https://orcid.org/0000-0001-6188-8806","https://orcid.org/0000-0003-3422-8305"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yongqing Zhang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052496001","display_name":"Shi-Zhuang Zhang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shi-Zhuang Zhang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100669041","display_name":"Hao Ding","orcid":"https://orcid.org/0000-0003-1608-7000","observed_orcids":["https://orcid.org/0000-0003-1608-7000"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hao Ding","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007857364","display_name":"Robert N. Fariss","orcid":"https://orcid.org/0000-0003-3227-7170","observed_orcids":["https://orcid.org/0000-0003-3227-7170"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Robert N. Fariss","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052081713","display_name":"Kevin G. Becker","orcid":"https://orcid.org/0000-0002-6794-6656","observed_orcids":["https://orcid.org/0000-0002-6794-6656"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kevin G. Becker","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073237636","display_name":"Johan Lennartsson","orcid":"https://orcid.org/0000-0003-0135-9560","observed_orcids":["https://orcid.org/0000-0003-0135-9560"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Johan Lennartsson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110586799","display_name":"Nobuo Nagai","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nobuo Nagai","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073365279","display_name":"Yihai Cao","orcid":"https://orcid.org/0000-0003-1308-0065","observed_orcids":["https://orcid.org/0000-0003-1308-0065"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yihai Cao","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5077886490","display_name":"Xuri Li","orcid":"https://orcid.org/0000-0002-8277-0767","observed_orcids":["https://orcid.org/0000-0002-8277-0767"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xuri Li","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.37409577,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"188","issue":"6","first_page":"i14","last_page":"i14"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.1559000015258789,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.1559000015258789,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10929","display_name":"Wnt/\u03b2-catenin signaling in development and cancer","score":0.14319999516010284,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.11800000071525574,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pdgf-cc","display_name":"PDGF-CC","score":0.9810000061988831},{"id":"https://openalex.org/keywords/neuronal-survival","display_name":"neuronal survival","score":0.7390000224113464},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.7149999737739563},{"id":"https://openalex.org/keywords/gsk-3beta-phosphorylation","display_name":"GSK3\u03b2 phosphorylation","score":0.9369999766349792},{"id":"https://openalex.org/keywords/retina","display_name":"retina","score":0.531000018119812},{"id":"https://openalex.org/keywords/brain-neurons","display_name":"brain neurons","score":0.8889999985694885},{"id":"https://openalex.org/keywords/neuroprotection","display_name":"neuroprotection","score":0.968999981880188}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9008906483650208},{"id":"https://openalex.org/C11960822","wikidata":"https://www.wikidata.org/wiki/Q242736","display_name":"Phosphorylation","level":2,"score":0.7814407348632812},{"id":"https://openalex.org/C2777093970","wikidata":"https://www.wikidata.org/wiki/Q169342","display_name":"Retina","level":2,"score":0.6866809725761414},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6747903227806091},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.6656871438026428},{"id":"https://openalex.org/C182996813","wikidata":"https://www.wikidata.org/wiki/Q910847","display_name":"GSK-3","level":3,"score":0.47952914237976074},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.4291980564594269},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3794260025024414},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3793373107910156},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.19846844673156738}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1083/jcb1886oia14","doi":"https://doi.org/10.1083/jcb1886oia14","is_oa":false,"landing_page_url":"https://doi.org/10.1083/jcb1886oia14","pdf_url":null,"source":{"id":"https://openalex.org/S96410829","display_name":"The Journal of Cell Biology","issn_l":"0021-9525","issn":["0021-9525","1540-8140"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Cell Biology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8023999929428101}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":1,"referenced_works":["https://openalex.org/W2136164716"],"related_works":["https://openalex.org/W3005651653","https://openalex.org/W1421685616","https://openalex.org/W2367947666","https://openalex.org/W2095929736","https://openalex.org/W1999017328","https://openalex.org/W7100119435","https://openalex.org/W2969255342","https://openalex.org/W1015337786","https://openalex.org/W2045160140","https://openalex.org/W1000278480"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-03T13:16:28.481748","created_date":"2022-05-12T00:00:00"}