{"id":"https://openalex.org/W4235128200","doi":"https://doi.org/10.1002/0470028637.met204","title":"Vanadium Haloperoxidases","display_name":"Vanadium Haloperoxidases","publication_year":2004,"publication_date":"2004-03-05","ids":{"openalex":"https://openalex.org/W4235128200","doi":"https://doi.org/10.1002/0470028637.met204"},"language":"en","primary_location":{"id":"doi:10.1002/0470028637.met204","doi":"https://doi.org/10.1002/0470028637.met204","is_oa":false,"landing_page_url":"https://doi.org/10.1002/0470028637.met204","pdf_url":null,"source":{"id":"https://openalex.org/S4363606030","display_name":"Handbook of Metalloproteins","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Handbook of Metalloproteins","raw_type":"other"},"volume":{"id":"https://openalex.org/W3118993215","display_name":"Handbook of Metalloproteins"},"type":"other","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5014177847","display_name":"Ron Wever","orcid":"https://orcid.org/0000-0003-3683-2821","observed_orcids":["https://orcid.org/0000-0003-3683-2821"]},"institutions":[{"id":"https://openalex.org/I887064364","display_name":"University of Amsterdam","ror":"https://ror.org/04dkp9463","country_code":"NL","type":"education","lineage":["https://openalex.org/I887064364"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Ron Wever","raw_affiliation_strings":["University of Amsterdam, Institute for Molecular Chemistry and E.C. Slater Institute, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Amsterdam, Institute for Molecular Chemistry and E.C. Slater Institute, The Netherlands","institution_ids":["https://openalex.org/I887064364"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063124546","display_name":"Wieger Hemrika","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I887064364","display_name":"University of Amsterdam","ror":"https://ror.org/04dkp9463","country_code":"NL","type":"education","lineage":["https://openalex.org/I887064364"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Wieger Hemrika","raw_affiliation_strings":["University of Amsterdam, Institute for Molecular Chemistry and E.C. Slater Institute, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Amsterdam, Institute for Molecular Chemistry and E.C. Slater Institute, The Netherlands","institution_ids":["https://openalex.org/I887064364"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I887064364"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12136","display_name":"Vanadium and Halogenation Chemistry","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1604","display_name":"Inorganic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12136","display_name":"Vanadium and Halogenation Chemistry","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1604","display_name":"Inorganic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11747","display_name":"Metal-Catalyzed Oxygenation Mechanisms","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1604","display_name":"Inorganic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11286","display_name":"Polyoxometalates: Synthesis and Applications","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vanadium-haloperoxidases","display_name":"vanadium haloperoxidases","score":0.9610000252723694},{"id":"https://openalex.org/keywords/vanadium-bromoperoxidase","display_name":"vanadium bromoperoxidase","score":0.9760000109672546},{"id":"https://openalex.org/keywords/halide-oxidation","display_name":"halide oxidation","score":0.8740000128746033},{"id":"https://openalex.org/keywords/hypohalous-acids","display_name":"hypohalous acids","score":0.9670000076293945},{"id":"https://openalex.org/keywords/enzyme-purification","display_name":"enzyme purification","score":0.9100000262260437},{"id":"https://openalex.org/keywords/enzyme-kinetics","display_name":"enzyme kinetics","score":0.609000027179718},{"id":"https://openalex.org/keywords/enzyme-structure","display_name":"enzyme structure","score":0.8870000243186951},{"id":"https://openalex.org/keywords/catalytic-mechanism","display_name":"catalytic mechanism","score":0.8460000157356262},{"id":"https://openalex.org/keywords/site-directed-mutagenesis","display_name":"site-directed mutagenesis","score":0.7950000166893005},{"id":"https://openalex.org/keywords/metal-coordination-sphere","display_name":"metal coordination sphere","score":0.5080000162124634}],"concepts":[{"id":"https://openalex.org/C2781116636","wikidata":"https://www.wikidata.org/wiki/Q426228","display_name":"Vanadate","level":2,"score":0.8539824485778809},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6977787017822266},{"id":"https://openalex.org/C504678139","wikidata":"https://www.wikidata.org/wiki/Q722","display_name":"Vanadium","level":2,"score":0.6891891956329346},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.6308586001396179},{"id":"https://openalex.org/C41183919","wikidata":"https://www.wikidata.org/wiki/Q423026","display_name":"Active site","level":3,"score":0.5207357406616211},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.4978482723236084},{"id":"https://openalex.org/C2777132085","wikidata":"https://www.wikidata.org/wiki/Q46220103","display_name":"Phosphate","level":2,"score":0.434872567653656},{"id":"https://openalex.org/C178666793","wikidata":"https://www.wikidata.org/wiki/Q422476","display_name":"Phosphatase","level":3,"score":0.4295289218425751},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.41327527165412903},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.3819989264011383},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.3378114700317383},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.3354983925819397},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.31825193762779236}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1002/0470028637.met204","doi":"https://doi.org/10.1002/0470028637.met204","is_oa":false,"landing_page_url":"https://doi.org/10.1002/0470028637.met204","pdf_url":null,"source":{"id":"https://openalex.org/S4363606030","display_name":"Handbook of Metalloproteins","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Handbook of Metalloproteins","raw_type":"other"},{"id":"pmh:oai:dare.uva.nl:openaire_cris_publications/1ccbd6e0-73ad-4af3-ad29-5a211898d8bb","doi":null,"is_oa":false,"landing_page_url":"https://handle.uba.uva.nl/personal/pure/en/publications/vanadium-haloperoxidases(1ccbd6e0-73ad-4af3-ad29-5a211898d8bb).html","pdf_url":null,"source":{"id":"https://openalex.org/S4306400088","display_name":"UvA-DARE (University of Amsterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I887064364","host_organization_name":"University of Amsterdam","host_organization_lineage":["https://openalex.org/I887064364"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Wever, R & Hemrika, W 2001, Vanadium Haloperoxidases. in A Messerschmidt (ed.), Handbook of Metalloproteins. John Wiley & Sons, Chichester. https://doi.org/10.1002/0470028637.met204","raw_type":"info:eu-repo/semantics/bookPart"},{"id":"pmh:uvapub:oai:dare.uva.nl:publications/1ccbd6e0-73ad-4af3-ad29-5a211898d8bb","doi":null,"is_oa":false,"landing_page_url":"https://dare.uva.nl/personal/pure/en/publications/vanadium-haloperoxidases(1ccbd6e0-73ad-4af3-ad29-5a211898d8bb).html","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Handbook of Metalloproteins","raw_type":"info:eu-repo/semantics/bookpart"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"score":0.6000000238418579,"display_name":"Clean water and sanitation","id":"https://metadata.un.org/sdg/6"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":62,"referenced_works":["https://openalex.org/W102709751","https://openalex.org/W127172438","https://openalex.org/W193929990","https://openalex.org/W1523040324","https://openalex.org/W1537734948","https://openalex.org/W1554625141","https://openalex.org/W1598570827","https://openalex.org/W1971936584","https://openalex.org/W1981714298","https://openalex.org/W1986430100","https://openalex.org/W1986536974","https://openalex.org/W1990828277","https://openalex.org/W1993943110","https://openalex.org/W1996670594","https://openalex.org/W1999802509","https://openalex.org/W1999972095","https://openalex.org/W2001865314","https://openalex.org/W2002328387","https://openalex.org/W2003071663","https://openalex.org/W2005159766","https://openalex.org/W2005304480","https://openalex.org/W2010269894","https://openalex.org/W2010647075","https://openalex.org/W2010649610","https://openalex.org/W2013916323","https://openalex.org/W2026490281","https://openalex.org/W2036801694","https://openalex.org/W2038147600","https://openalex.org/W2042019539","https://openalex.org/W2042276156","https://openalex.org/W2049425885","https://openalex.org/W2057680304","https://openalex.org/W2058211231","https://openalex.org/W2058219232","https://openalex.org/W2058344173","https://openalex.org/W2069193154","https://openalex.org/W2069300781","https://openalex.org/W2076128136","https://openalex.org/W2077766071","https://openalex.org/W2082343723","https://openalex.org/W2082931241","https://openalex.org/W2083679772","https://openalex.org/W2084172135","https://openalex.org/W2084692743","https://openalex.org/W2085261773","https://openalex.org/W2090574380","https://openalex.org/W2104393742","https://openalex.org/W2122102685","https://openalex.org/W2122531216","https://openalex.org/W2144006919","https://openalex.org/W2144895545","https://openalex.org/W2145722587","https://openalex.org/W2150535215","https://openalex.org/W2156721231","https://openalex.org/W2167532173","https://openalex.org/W2225537503","https://openalex.org/W2288332668","https://openalex.org/W2489478261","https://openalex.org/W2902817392","https://openalex.org/W4211227176","https://openalex.org/W4252616354","https://openalex.org/W4300712202"],"related_works":["https://openalex.org/W1967309048","https://openalex.org/W1998352258","https://openalex.org/W2160929481","https://openalex.org/W2467617651","https://openalex.org/W57099253","https://openalex.org/W2002936941","https://openalex.org/W174541704","https://openalex.org/W2081726090","https://openalex.org/W2083969369","https://openalex.org/W31545847"],"abstract_inverted_index":{"Abstract":[0],"This":[1],"chapter":[2],"describes":[3],"the":[4,7,11,22,26,31,72,85,96,102,107,112,117],"occurrence":[5],"and":[6,14,36,44,53],"biological":[8],"function":[9],"of":[10,28,39,75,81,87,106,116],"vanadium":[12,97],"bromoperoxidases":[13],"chloroperoxidases.":[15],"These":[16],"enzymes":[17,41],"that":[18,100],"contain":[19],"vanadate":[20],"as":[21,58,60],"prosthetic":[23],"group":[24,80],"catalyze":[25],"oxidation":[27],"halides":[29],"to":[30],"corresponding":[32],"hypohalous":[33],"acids.":[34],"Purification":[35],"molecular":[37],"characterization":[38],"these":[40],"is":[42,48,93],"reported":[43],"a":[45,51,54,78,90],"detailed":[46],"comparison":[47],"made":[49],"between":[50],"bromoperoxidase":[52],"chloroperoxidase,":[55],"both":[56],"kinetically":[57],"well":[59],"structurally.":[61],"The":[62],"vanadate\u2010binding":[63],"site":[64,74],"in":[65,77,104,111],"haloperoxidases":[66],"shows":[67],"an":[68],"interesting":[69],"homology":[70],"with":[71],"binding":[73],"phosphate":[76],"large":[79],"phosphatases.":[82],"Finally,":[83],"on":[84],"basis":[86],"mutagenesis":[88],"studies,":[89],"catalytic":[91],"mechanism":[92],"presented":[94],"for":[95],"chloroperoxidase":[98],"activity":[99],"details":[101],"role":[103],"catalysis":[105],"amino":[108],"acid":[109],"residues":[110],"first":[113],"coordination":[114],"sphere":[115],"metal":[118],"oxide.":[119]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-10T09:11:00.788812","created_date":"2025-10-10T00:00:00"}