{"id":"https://openalex.org/W4234119366","doi":"https://doi.org/10.1002/cne.23322","title":"Alterations in the motor neuron\u2013renshaw cell circuit in the Sod1G93A mouse model","display_name":"Alterations in the motor neuron\u2013renshaw cell circuit in the Sod1G93A mouse model","publication_year":2013,"publication_date":"2013-03-19","ids":{"openalex":"https://openalex.org/W4234119366","doi":"https://doi.org/10.1002/cne.23322"},"language":"en","primary_location":{"id":"doi:10.1002/cne.23322","doi":"https://doi.org/10.1002/cne.23322","is_oa":true,"landing_page_url":"https://doi.org/10.1002/cne.23322","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cne.23322","source":{"id":"https://openalex.org/S4210186231","display_name":"The Journal of Comparative Neurology","issn_l":"0021-9967","issn":["0021-9967","0092-7317","1096-9861","1550-7130"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Comparative Neurology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cne.23322","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028378222","display_name":"Hanna Wootz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I123387679","display_name":"Uppsala University","ror":"https://ror.org/048a87296","country_code":"SE","type":"education","lineage":["https://openalex.org/I123387679"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Hanna Wootz","raw_affiliation_strings":["Department of Neuroscience, Uppsala University, 75124 Uppsala, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, Uppsala University, 75124 Uppsala, Sweden","institution_ids":["https://openalex.org/I123387679"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060622633","display_name":"Eileen FitzSimons\u2010Kantamneni","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19648265","display_name":"Wright State University","ror":"https://ror.org/04qk6pt94","country_code":"US","type":"education","lineage":["https://openalex.org/I19648265"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eileen FitzSimons\u2010Kantamneni","raw_affiliation_strings":["Department of Neurosciences, Cell Biology, and Physiology, Wright State University, Dayton, Ohio 45435","E. Fitzsimons-Kantamneni and M. Larhammar contributed equally to this work"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosciences, Cell Biology, and Physiology, Wright State University, Dayton, Ohio 45435","institution_ids":["https://openalex.org/I19648265"]},{"raw_affiliation_string":"E. Fitzsimons-Kantamneni and M. Larhammar contributed equally to this work","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084284706","display_name":"Martin Larhammar","orcid":"https://orcid.org/0000-0002-1547-6760","observed_orcids":["https://orcid.org/0000-0002-1547-6760"]},"institutions":[{"id":"https://openalex.org/I123387679","display_name":"Uppsala University","ror":"https://ror.org/048a87296","country_code":"SE","type":"education","lineage":["https://openalex.org/I123387679"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Martin Larhammar","raw_affiliation_strings":["Department of Neuroscience, Uppsala University, 75124 Uppsala, Sweden","E. Fitzsimons-Kantamneni and M. Larhammar contributed equally to this work"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, Uppsala University, 75124 Uppsala, Sweden","institution_ids":["https://openalex.org/I123387679"]},{"raw_affiliation_string":"E. Fitzsimons-Kantamneni and M. Larhammar contributed equally to this work","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068202791","display_name":"Travis M. Rotterman","orcid":"https://orcid.org/0000-0003-0044-7948","observed_orcids":["https://orcid.org/0000-0003-0044-7948"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Travis M. Rotterman","raw_affiliation_strings":["Department of Physiology, Emory University, Atlanta, Georgia 30322"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, Emory University, Atlanta, Georgia 30322","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046921508","display_name":"Anders Enjin","orcid":"https://orcid.org/0000-0001-7167-9434","observed_orcids":["https://orcid.org/0000-0001-7167-9434"]},"institutions":[{"id":"https://openalex.org/I123387679","display_name":"Uppsala University","ror":"https://ror.org/048a87296","country_code":"SE","type":"education","lineage":["https://openalex.org/I123387679"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Anders Enjin","raw_affiliation_strings":["Department of Neuroscience, Uppsala University, 75124 Uppsala, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, Uppsala University, 75124 Uppsala, Sweden","institution_ids":["https://openalex.org/I123387679"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056318504","display_name":"Kalicharan Patra","orcid":"https://orcid.org/0000-0001-8335-5218","observed_orcids":["https://orcid.org/0000-0001-8335-5218"]},"institutions":[{"id":"https://openalex.org/I123387679","display_name":"Uppsala University","ror":"https://ror.org/048a87296","country_code":"SE","type":"education","lineage":["https://openalex.org/I123387679"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Kalicharan Patra","raw_affiliation_strings":["Department of Neuroscience, Uppsala University, 75124 Uppsala, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, Uppsala University, 75124 Uppsala, Sweden","institution_ids":["https://openalex.org/I123387679"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000988679","display_name":"Elodie Andr\u00e9","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I123387679","display_name":"Uppsala University","ror":"https://ror.org/048a87296","country_code":"SE","type":"education","lineage":["https://openalex.org/I123387679"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Elodie Andr\u00e9","raw_affiliation_strings":["Department of Neuroscience, Uppsala University, 75124 Uppsala, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, Uppsala University, 75124 Uppsala, Sweden","institution_ids":["https://openalex.org/I123387679"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036161196","display_name":"Brigitte van Zundert","orcid":"https://orcid.org/0000-0002-4129-9972","observed_orcids":["https://orcid.org/0000-0002-4129-9972"]},"institutions":[{"id":"https://openalex.org/I13897259","display_name":"Universidad Andr\u00e9s Bello","ror":"https://ror.org/01qq57711","country_code":"CL","type":"education","lineage":["https://openalex.org/I13897259"]},{"id":"https://openalex.org/I144112489","display_name":"McGovern Institute for Brain Research","ror":"https://ror.org/05ymca674","country_code":"US","type":"facility","lineage":["https://openalex.org/I144112489","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["CL","US"],"is_corresponding":false,"raw_author_name":"Brigitte Van Zundert","raw_affiliation_strings":["Center for Biomedical Research, Faculty of Biological Sciences and Faculty of Medicine, Universidad Andres Bello, Santiago, Chile","McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Biomedical Research, Faculty of Biological Sciences and Faculty of Medicine, Universidad Andres Bello, Santiago, Chile","institution_ids":["https://openalex.org/I13897259"]},{"raw_affiliation_string":"McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139","institution_ids":["https://openalex.org/I144112489","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048058625","display_name":"Klas Kullander","orcid":"https://orcid.org/0000-0001-6418-5460","observed_orcids":["https://orcid.org/0000-0001-6418-5460"]},"institutions":[{"id":"https://openalex.org/I123387679","display_name":"Uppsala University","ror":"https://ror.org/048a87296","country_code":"SE","type":"education","lineage":["https://openalex.org/I123387679"]},{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]},{"id":"https://openalex.org/I2800139495","display_name":"Science for Life Laboratory","ror":"https://ror.org/04ev03g22","country_code":"SE","type":"facility","lineage":["https://openalex.org/I2800139495"]}],"countries":["SE","US"],"is_corresponding":true,"raw_author_name":"Klas Kullander","raw_affiliation_strings":["Department of Neuroscience, Uppsala University, 75124 Uppsala, Sweden","Francisco J. Alvarez, Department of Physiology, Emory University, Whitehead Research Building, Room 642, 615 Michael Street, Atlanta, GA, 30322-3110","Klas Kullander, Department of Neuroscience, Uppsala University, Box 593, 751 24 Uppsala, Sweden","Science for Life Laboratory, Uppsala University, 75124 Uppsala, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, Uppsala University, 75124 Uppsala, Sweden","institution_ids":["https://openalex.org/I123387679"]},{"raw_affiliation_string":"Francisco J. Alvarez, Department of Physiology, Emory University, Whitehead Research Building, Room 642, 615 Michael Street, Atlanta, GA, 30322-3110","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Klas Kullander, Department of Neuroscience, Uppsala University, Box 593, 751 24 Uppsala, Sweden","institution_ids":["https://openalex.org/I123387679"]},{"raw_affiliation_string":"Science for Life Laboratory, Uppsala University, 75124 Uppsala, Sweden","institution_ids":["https://openalex.org/I123387679","https://openalex.org/I2800139495"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003096476","display_name":"Francisco J. \u00c1lvarez","orcid":"https://orcid.org/0000-0001-7011-3244","observed_orcids":["https://orcid.org/0000-0001-7011-3244"]},"institutions":[{"id":"https://openalex.org/I123387679","display_name":"Uppsala University","ror":"https://ror.org/048a87296","country_code":"SE","type":"education","lineage":["https://openalex.org/I123387679"]},{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]},{"id":"https://openalex.org/I19648265","display_name":"Wright State University","ror":"https://ror.org/04qk6pt94","country_code":"US","type":"education","lineage":["https://openalex.org/I19648265"]}],"countries":["SE","US"],"is_corresponding":true,"raw_author_name":"Francisco J. Alvarez","raw_affiliation_strings":["Department of Neurosciences, Cell Biology, and Physiology, Wright State University, Dayton, Ohio 45435","Department of Physiology, Emory University, Atlanta, Georgia 30322","Francisco J. Alvarez, Department of Physiology, Emory University, Whitehead Research Building, Room 642, 615 Michael Street, Atlanta, GA, 30322-3110","Klas Kullander, Department of Neuroscience, Uppsala University, Box 593, 751 24 Uppsala, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosciences, Cell Biology, and Physiology, Wright State University, Dayton, Ohio 45435","institution_ids":["https://openalex.org/I19648265"]},{"raw_affiliation_string":"Department of Physiology, Emory University, Atlanta, Georgia 30322","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Francisco J. Alvarez, Department of Physiology, Emory University, Whitehead Research Building, Room 642, 615 Michael Street, Atlanta, GA, 30322-3110","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Klas Kullander, Department of Neuroscience, Uppsala University, Box 593, 751 24 Uppsala, Sweden","institution_ids":["https://openalex.org/I123387679"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5003096476","https://openalex.org/A5048058625"],"corresponding_institution_ids":["https://openalex.org/I123387679","https://openalex.org/I150468666","https://openalex.org/I19648265","https://openalex.org/I2800139495"],"apc_list":{"value":5450,"currency":"USD","value_usd":5450},"apc_paid":null,"fwci":0.1925,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.53205311,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"521","issue":"7","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10855","display_name":"Amyotrophic Lateral Sclerosis Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10855","display_name":"Amyotrophic Lateral Sclerosis Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12400","display_name":"Neurogenetic and Muscular Disorders Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/amyotrophic-lateral-sclerosis","display_name":"amyotrophic lateral sclerosis","score":0.9940000176429749},{"id":"https://openalex.org/keywords/renshaw-cells","display_name":"Renshaw cells","score":0.9150000214576721},{"id":"https://openalex.org/keywords/sod1g93a-mouse-model","display_name":"SOD1 G93A mouse model","score":0.8009999990463257},{"id":"https://openalex.org/keywords/calbindin","display_name":"calbindin","score":0.7020000219345093},{"id":"https://openalex.org/keywords/chrna2","display_name":"CHRNA2","score":0.8180000185966492},{"id":"https://openalex.org/keywords/vesicular-acetylcholine-transporter","display_name":"vesicular acetylcholine transporter","score":0.871999979019165},{"id":"https://openalex.org/keywords/motor-neuron-survival","display_name":"motor neuron survival","score":0.4020000100135803},{"id":"https://openalex.org/keywords/axonal-sprouting","display_name":"axonal sprouting","score":0.7239999771118164}],"concepts":[{"id":"https://openalex.org/C2778037872","wikidata":"https://www.wikidata.org/wiki/Q1756451","display_name":"Renshaw cell","level":3,"score":0.9238605499267578},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.7989119291305542},{"id":"https://openalex.org/C2776752467","wikidata":"https://www.wikidata.org/wiki/Q1133903","display_name":"Motor neuron","level":3,"score":0.7472535371780396},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6607970595359802},{"id":"https://openalex.org/C2781100881","wikidata":"https://www.wikidata.org/wiki/Q21123811","display_name":"NeuN","level":3,"score":0.6606999635696411},{"id":"https://openalex.org/C2779530196","wikidata":"https://www.wikidata.org/wiki/Q178999","display_name":"Axon","level":2,"score":0.49970054626464844},{"id":"https://openalex.org/C2780596555","wikidata":"https://www.wikidata.org/wiki/Q206901","display_name":"Amyotrophic lateral sclerosis","level":3,"score":0.48389706015586853},{"id":"https://openalex.org/C26265296","wikidata":"https://www.wikidata.org/wiki/Q408713","display_name":"Calbindin","level":3,"score":0.44280025362968445},{"id":"https://openalex.org/C2779296341","wikidata":"https://www.wikidata.org/wiki/Q1500732","display_name":"Interneuron","level":3,"score":0.4345847964286804},{"id":"https://openalex.org/C17077164","wikidata":"https://www.wikidata.org/wiki/Q1185869","display_name":"Inhibitory postsynaptic potential","level":2,"score":0.43349263072013855},{"id":"https://openalex.org/C2780775167","wikidata":"https://www.wikidata.org/wiki/Q9606","display_name":"Spinal cord","level":2,"score":0.4282488226890564},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.14788994193077087},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.13119205832481384},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.10139825940132141},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/cne.23322","doi":"https://doi.org/10.1002/cne.23322","is_oa":true,"landing_page_url":"https://doi.org/10.1002/cne.23322","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cne.23322","source":{"id":"https://openalex.org/S4210186231","display_name":"The Journal of Comparative Neurology","issn_l":"0021-9967","issn":["0021-9967","0092-7317","1096-9861","1550-7130"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Comparative Neurology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1002/cne.23322","doi":"https://doi.org/10.1002/cne.23322","is_oa":true,"landing_page_url":"https://doi.org/10.1002/cne.23322","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cne.23322","source":{"id":"https://openalex.org/S4210186231","display_name":"The Journal of Comparative Neurology","issn_l":"0021-9967","issn":["0021-9967","0092-7317","1096-9861","1550-7130"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Comparative Neurology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4234119366.pdf"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4232246139","https://openalex.org/W2023618174","https://openalex.org/W7170997150","https://openalex.org/W2056300681","https://openalex.org/W4313650739","https://openalex.org/W176373175","https://openalex.org/W4311477305","https://openalex.org/W2612111329","https://openalex.org/W3164066979","https://openalex.org/W2974587615"],"abstract_inverted_index":{"Abstract":[0],"Motor":[1],"neurons":[2,95,108,198],"become":[3],"hyperexcitable":[4],"during":[5,51,124],"progression":[6,126],"of":[7,53,121,167,185,217,229,242],"amyotrophic":[8],"lateral":[9],"sclerosis":[10],"(ALS).":[11],"This":[12],"abnormal":[13,42],"firing":[14],"behavior":[15],"has":[16,29],"been":[17,30,57],"explained":[18],"by":[19],"changes":[20,33],"in":[21,34,127,145,239],"their":[22],"membrane":[23],"properties,":[24],"but":[25,141],"more":[26,200],"recently":[27],"it":[28],"suggested":[31],"that":[32,47,67,214],"premotor":[35],"circuits":[36,46],"may":[37,48],"also":[38],"contribute":[39],"to":[40,138],"this":[41],"activity.":[43],"The":[44],"specific":[45],"be":[49],"altered":[50],"development":[52],"ALS":[54,230],"have":[55],"not":[56],"investigated.":[58],"Here":[59],"we":[60,115],"examined":[61],"the":[62,117,128,190,215,233],"Renshaw":[63,80,135,177,193,223],"cell":[64,194],"recurrent":[65,234],"circuit":[66],"exerts":[68],"inhibitory":[69,235],"feedback":[70],"control":[71,241],"on":[72,196,222],"motor":[73,94,107,149,186,197,210,219,243],"neuron":[74,244],"firing.":[75,245],"Using":[76],"two":[77,90,103],"markers":[78,92,104,152],"for":[79,93,105],"cells":[81,123,136,178,224],"(calbindin":[82],"and":[83,97,102,110,119,159,170,231],"cholinergic":[84],"nicotinic":[85],"receptor":[86],"subunit":[87],"alpha2":[88],"[Chrna2]),":[89],"general":[91],"(NeuN":[96],"vesicular":[98],"acethylcholine":[99],"transporter":[100],"[VAChT]),":[101],"fast":[106],"(Chondrolectin":[109],"calcitonin\u2010related":[111],"polypeptide":[112],"alpha":[113],"[Calca]),":[114],"analyzed":[116],"survival":[118],"connectivity":[120],"these":[122],"disease":[125],"Sod1G93A":[129],"mouse":[130],"model.":[131],"Most":[132],"calbindin\u2010immunoreactive":[133],"(IR)":[134],"survive":[137],"end":[139,162],"stage":[140,163],"downregulate":[142],"postsynaptic":[143],"Chrna2":[144,171],"presymptomatic":[146],"animals.":[147],"In":[148],"neurons,":[150],"some":[151],"are":[153],"downregulated":[154],"early":[155,227],"(NeuN,":[156],"VAChT,":[157],"Chondrolectin)":[158],"others":[160],"at":[161,226],"(Calca).":[164],"Early":[165],"downregulation":[166],"presynaptic":[168,218],"VAChT":[169],"was":[172],"correlated":[173],"with":[174],"disconnection":[175],"from":[176],"as":[179,181],"well":[180],"major":[182],"structural":[183],"abnormalities":[184],"axon":[187,220],"synapses":[188,195],"inside":[189],"spinal":[191],"cord.":[192],"underwent":[199],"complex":[201],"changes,":[202],"including":[203],"transitional":[204],"sprouting":[205],"preferentially":[206],"over":[207],"remaining":[208],"NeuN\u2010IR":[209],"neurons.":[211],"We":[212],"conclude":[213],"loss":[216],"input":[221],"occurs":[225],"stages":[228],"disconnects":[232],"circuit,":[236],"presumably":[237],"resulting":[238],"diminished":[240],"\u00a9":[246],"2012":[247],"Wiley":[248],"Periodicals,":[249],"Inc.":[250]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2022-05-12T00:00:00"}