{"id":"https://openalex.org/W4233980210","doi":"https://doi.org/10.20956/nmsj.v6i1.12243","title":"The Potential of Rosuvastatin in Stabilizing Lipid Profile and Improving Clinical Outcomes in Covid-19 Patients with Coronary Heart Disease","display_name":"The Potential of Rosuvastatin in Stabilizing Lipid Profile and Improving Clinical Outcomes in Covid-19 Patients with Coronary Heart Disease","publication_year":2021,"publication_date":"2021-10-21","ids":{"openalex":"https://openalex.org/W4233980210","doi":"https://doi.org/10.20956/nmsj.v6i1.12243"},"language":"en","primary_location":{"id":"doi:10.20956/nmsj.v6i1.12243","doi":"https://doi.org/10.20956/nmsj.v6i1.12243","is_oa":true,"landing_page_url":"https://doi.org/10.20956/nmsj.v6i1.12243","pdf_url":"https://journal.unhas.ac.id/index.php/jmednus/article/download/12243/7432","source":{"id":"https://openalex.org/S4210224395","display_name":"Nusantara Medical Science Journal","issn_l":"2460-9757","issn":["2460-9757","2597-7288"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310315277","host_organization_name":"Hasanuddin University","host_organization_lineage":["https://openalex.org/P4310315277"],"host_organization_lineage_names":["Hasanuddin University"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nusantara Medical Science Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://journal.unhas.ac.id/index.php/jmednus/article/download/12243/7432","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5069848621","display_name":"William Suciangto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98301867","display_name":"Hasanuddin University","ror":"https://ror.org/00da1gf19","country_code":"ID","type":"education","lineage":["https://openalex.org/I98301867"]}],"countries":["ID"],"is_corresponding":true,"raw_author_name":"William Suciangto","raw_affiliation_strings":["Faculty of Medicine, Hasanuddin University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine, Hasanuddin University","institution_ids":["https://openalex.org/I98301867"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067321096","display_name":"Haerani Rasyid","orcid":"https://orcid.org/0000-0001-7404-2973","observed_orcids":["https://orcid.org/0000-0001-7404-2973"]},"institutions":[{"id":"https://openalex.org/I98301867","display_name":"Hasanuddin University","ror":"https://ror.org/00da1gf19","country_code":"ID","type":"education","lineage":["https://openalex.org/I98301867"]}],"countries":["ID"],"is_corresponding":true,"raw_author_name":"Haerani Rasyid","raw_affiliation_strings":["Nephrology and Hypertension Division, Internal Medicine Department, Faculty of Medicine, Hasanuddin University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nephrology and Hypertension Division, Internal Medicine Department, Faculty of Medicine, Hasanuddin University","institution_ids":["https://openalex.org/I98301867"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028488773","display_name":"Nada Indira Ramadhani Nasrum","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98301867","display_name":"Hasanuddin University","ror":"https://ror.org/00da1gf19","country_code":"ID","type":"education","lineage":["https://openalex.org/I98301867"]}],"countries":["ID"],"is_corresponding":true,"raw_author_name":"Nada Indira Ramadhani Nasrum","raw_affiliation_strings":["Medical Faculty Hasanuddin University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Faculty Hasanuddin University","institution_ids":["https://openalex.org/I98301867"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5077506019","display_name":"Muhammad Zaki Rahmani","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98301867","display_name":"Hasanuddin University","ror":"https://ror.org/00da1gf19","country_code":"ID","type":"education","lineage":["https://openalex.org/I98301867"]}],"countries":["ID"],"is_corresponding":true,"raw_author_name":"Muhammad Zaki Rahmani","raw_affiliation_strings":["Medical Faculty Hasanuddin University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Faculty Hasanuddin University","institution_ids":["https://openalex.org/I98301867"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5028488773","https://openalex.org/A5067321096","https://openalex.org/A5069848621","https://openalex.org/A5077506019"],"corresponding_institution_ids":["https://openalex.org/I98301867"],"apc_list":null,"apc_paid":null,"fwci":0.0848,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.39065742,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":null,"issue":null,"first_page":"54","last_page":"65"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10041","display_name":"COVID-19 Clinical Research Studies","score":0.54830002784729,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10041","display_name":"COVID-19 Clinical Research Studies","score":0.54830002784729,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.4341000020503998,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12465","display_name":"Cancer, Lipids, and Metabolism","score":0.0052999998442828655,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rosuvastatin","display_name":"rosuvastatin","score":0.9829999804496765},{"id":"https://openalex.org/keywords/statins","display_name":"statins","score":0.7979999780654907},{"id":"https://openalex.org/keywords/covid-19","display_name":"COVID-19 pandemic","score":0.9990000128746033},{"id":"https://openalex.org/keywords/sars-cov-2","display_name":"SARS-CoV-2","score":0.9599999785423279},{"id":"https://openalex.org/keywords/coronary-artery-disease","display_name":"coronary artery disease","score":0.9789999723434448},{"id":"https://openalex.org/keywords/lipid-profile","display_name":"lipid profile","score":0.9909999966621399},{"id":"https://openalex.org/keywords/ldl-cholesterol","display_name":"LDL cholesterol","score":0.9649999737739563},{"id":"https://openalex.org/keywords/hdl-cholesterol","display_name":"HDL cholesterol","score":1.0},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.8790000081062317},{"id":"https://openalex.org/keywords/main-protease","display_name":"main protease","score":0.7850000262260437},{"id":"https://openalex.org/keywords/adjuvant-therapy","display_name":"adjuvant therapy","score":0.9639999866485596}],"concepts":[{"id":"https://openalex.org/C2780499067","wikidata":"https://www.wikidata.org/wiki/Q415159","display_name":"Rosuvastatin","level":2,"score":0.854317843914032},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8199167251586914},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5830948352813721},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.560164749622345},{"id":"https://openalex.org/C2776839432","wikidata":"https://www.wikidata.org/wiki/Q954845","display_name":"Statin","level":2,"score":0.5502285957336426},{"id":"https://openalex.org/C2778270857","wikidata":"https://www.wikidata.org/wiki/Q2723972","display_name":"Lipid profile","level":3,"score":0.5285122394561768},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5124254822731018},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.4970715343952179},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.4511423110961914},{"id":"https://openalex.org/C2777698277","wikidata":"https://www.wikidata.org/wiki/Q266018","display_name":"Acute coronary syndrome","level":3,"score":0.44776707887649536},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.43786364793777466},{"id":"https://openalex.org/C89623803","wikidata":"https://www.wikidata.org/wiki/Q12184","display_name":"Pandemic","level":5,"score":0.4294779896736145},{"id":"https://openalex.org/C2777648638","wikidata":"https://www.wikidata.org/wiki/Q57751738","display_name":"Coronavirus","level":5,"score":0.42698997259140015},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.39385348558425903},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3723362684249878},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.11264488101005554},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.10375431180000305}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.20956/nmsj.v6i1.12243","doi":"https://doi.org/10.20956/nmsj.v6i1.12243","is_oa":true,"landing_page_url":"https://doi.org/10.20956/nmsj.v6i1.12243","pdf_url":"https://journal.unhas.ac.id/index.php/jmednus/article/download/12243/7432","source":{"id":"https://openalex.org/S4210224395","display_name":"Nusantara Medical Science Journal","issn_l":"2460-9757","issn":["2460-9757","2597-7288"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310315277","host_organization_name":"Hasanuddin University","host_organization_lineage":["https://openalex.org/P4310315277"],"host_organization_lineage_names":["Hasanuddin University"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nusantara Medical Science Journal","raw_type":"journal-article"},{"id":"pmh:oai:ojs.unhas:article/12243","doi":null,"is_oa":true,"landing_page_url":"https://journal.unhas.ac.id/index.php/index/article/view/12243","pdf_url":null,"source":{"id":"https://openalex.org/S4210224395","display_name":"Nusantara Medical Science Journal","issn_l":"2460-9757","issn":["2460-9757","2597-7288"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310315277","host_organization_name":"Hasanuddin University","host_organization_lineage":["https://openalex.org/P4310315277"],"host_organization_lineage_names":["Hasanuddin University"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"10.20956/nmsj.v6i1","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.20956/nmsj.v6i1.12243","doi":"https://doi.org/10.20956/nmsj.v6i1.12243","is_oa":true,"landing_page_url":"https://doi.org/10.20956/nmsj.v6i1.12243","pdf_url":"https://journal.unhas.ac.id/index.php/jmednus/article/download/12243/7432","source":{"id":"https://openalex.org/S4210224395","display_name":"Nusantara Medical Science Journal","issn_l":"2460-9757","issn":["2460-9757","2597-7288"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310315277","host_organization_name":"Hasanuddin University","host_organization_lineage":["https://openalex.org/P4310315277"],"host_organization_lineage_names":["Hasanuddin University"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nusantara Medical Science Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4233980210.pdf","grobid_xml":"https://content.openalex.org/works/W4233980210.grobid-xml"},"referenced_works_count":39,"referenced_works":["https://openalex.org/W1985745311","https://openalex.org/W1992279413","https://openalex.org/W2079838050","https://openalex.org/W2104650041","https://openalex.org/W2126372860","https://openalex.org/W2134105637","https://openalex.org/W2227600949","https://openalex.org/W2570787279","https://openalex.org/W2591850452","https://openalex.org/W2766824927","https://openalex.org/W2793221482","https://openalex.org/W2884138938","https://openalex.org/W2909249787","https://openalex.org/W3006116566","https://openalex.org/W3006783394","https://openalex.org/W3014003872","https://openalex.org/W3014808081","https://openalex.org/W3015186860","https://openalex.org/W3015405225","https://openalex.org/W3015841799","https://openalex.org/W3019360767","https://openalex.org/W3021315728","https://openalex.org/W3022155659","https://openalex.org/W3023838751","https://openalex.org/W3023991776","https://openalex.org/W3029531761","https://openalex.org/W3031365196","https://openalex.org/W3032127696","https://openalex.org/W3036683212","https://openalex.org/W3038063455","https://openalex.org/W3042070402","https://openalex.org/W3043773740","https://openalex.org/W3083027330","https://openalex.org/W3091397170","https://openalex.org/W3104440425","https://openalex.org/W3154294714","https://openalex.org/W3173737047","https://openalex.org/W6778110575","https://openalex.org/W6779885857"],"related_works":["https://openalex.org/W4210677073","https://openalex.org/W3092290512","https://openalex.org/W4296109585","https://openalex.org/W4282007359","https://openalex.org/W3119953938","https://openalex.org/W4206799179","https://openalex.org/W3110716668","https://openalex.org/W3097815782","https://openalex.org/W3124120476","https://openalex.org/W3166005922"],"abstract_inverted_index":{"Introduction":[0],":":[1,104,127],"The":[2,105],"novel":[3],"coronavirus":[4,14],"disease":[5,52],"(COVID-19)":[6],"pandemic,":[7],"caused":[8],"by":[9,25,168,174],"severe":[10,27],"acute":[11],"respiratory":[12],"syndrome":[13],"2":[15],"(SARS-CoV-2),":[16],"remains":[17],"a":[18,171],"global":[19],"challenge":[20],"since":[21],"December":[22],"2019":[23],"cause":[24],"its":[26,91],"symptoms":[28],"and":[29,90,114,144,163],"high":[30],"mortality":[31],"rate.":[32],"Some":[33],"comorbidities":[34],"are":[35,55],"associated":[36],"with":[37,101,198],"clinical":[38,96,193],"outcomes":[39],"in":[40,62,78,108,195],"COVID-19":[41,79,99,196],"patients,":[42],"one":[43],"of":[44,88,98],"them":[45],"is":[46,111],"cardiovascular":[47],"disease,":[48],"including":[49],"coronary":[50],"heart":[51],"(CHD).":[53],"Statins":[54],"popularly":[56],"used":[57,107],"as":[58,189],"the":[59,68,75,86,95,116,137,141,146,161,186],"lipid":[60,69],"controller":[61],"CHD":[63],"patients.":[64,80],"Not":[65],"only":[66],"controlling":[67],"profile,":[70],"statins":[71,89,133,184],"also":[72,139,156],"can":[73],"reduce":[74,160],"inflammation":[76,162],"process":[77],"This":[81],"review":[82,115],"aims":[83],"to":[84,93,112,135,159],"determine":[85],"activity":[87],"potential":[92,187],"improve":[94],"manifestation":[97],"patients":[100,197],"CHD.":[102,199],"Methods":[103],"method":[106],"this":[109],"paper":[110],"examine":[113],"literature":[117],"journal":[118],"that":[119,132,154,183],"has":[120],"been":[121],"published":[122],"last":[123],"10":[124],"years.":[125],"Results":[126],"Recent":[128],"studies":[129],"have":[130,152,157,185],"shown":[131,153],"capable":[134],"control":[136],"lipid,":[138],"lowering":[140],"LDL":[142],"cholesterol":[143],"increasing":[145],"HDL":[147],"cholesterol.":[148],"And":[149],"other":[150],"trials":[151],"statin":[155],"ability":[158],"inhibit":[164],"further":[165],"cell":[166],"damage":[167],"binding":[169],"mpro,":[170],"protease":[172],"produced":[173],"SARS-COV2.":[175],"Conclusions:":[176],"Based":[177],"on":[178],"those":[179],"studies,":[180],"we":[181],"conclude":[182],"effect":[188],"adjuvant":[190],"therapy":[191],"for":[192],"improvement":[194]},"counts_by_year":[{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2022-05-12T00:00:00"}