{"id":"https://openalex.org/W4232899345","doi":"https://doi.org/10.1142/9789811235795_0011","title":"Direct NMR observation of a substrate protein bound to the chaperonin GroEL","display_name":"Direct NMR observation of a substrate protein bound to the chaperonin GroEL","publication_year":2021,"publication_date":"2021-08-12","ids":{"openalex":"https://openalex.org/W4232899345","doi":"https://doi.org/10.1142/9789811235795_0011"},"language":"en","primary_location":{"id":"doi:10.1142/9789811235795_0011","doi":"https://doi.org/10.1142/9789811235795_0011","is_oa":false,"landing_page_url":"https://doi.org/10.1142/9789811235795_0011","pdf_url":null,"source":{"id":"https://openalex.org/S4306464320","display_name":"WORLD SCIENTIFIC eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319815","host_organization_name":"World Scientific","host_organization_lineage":["https://openalex.org/P4310319815"],"host_organization_lineage_names":["World Scientific"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NMR with Biological Macromolecules in Solution","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W3183979427","display_name":"NMR with Biological Macromolecules in Solution"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077981371","display_name":"Reto Horst","orcid":"https://orcid.org/0000-0002-2684-0310","observed_orcids":["https://orcid.org/0000-0002-2684-0310"]},"institutions":[{"id":"https://openalex.org/I123431417","display_name":"Scripps Research Institute","ror":"https://ror.org/02dxx6824","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I123431417"]},{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]},{"id":"https://openalex.org/I4405255162","display_name":"Institute of Molecular Biology and Biophysics","ror":"https://ror.org/02p702482","country_code":"CH","type":"facility","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088","https://openalex.org/I4405255162"]}],"countries":["CH","US"],"is_corresponding":false,"raw_author_name":"Reto Horst","raw_affiliation_strings":["Institut f\u00fcr Molekularbiologie und Biophysik, Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich, CH-8093 Z\u00fcrich, Switzerland","The Scripps Research Institute, La Jolla, CA 92037, US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut f\u00fcr Molekularbiologie und Biophysik, Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich, CH-8093 Z\u00fcrich, Switzerland","institution_ids":["https://openalex.org/I35440088","https://openalex.org/I4405255162"]},{"raw_affiliation_string":"The Scripps Research Institute, La Jolla, CA 92037, US","institution_ids":["https://openalex.org/I123431417"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009719847","display_name":"Eric B. Bertelsen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric B. Bertelsen","raw_affiliation_strings":["Howard Hughes Medical Institute and Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, U.S"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Howard Hughes Medical Institute and Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, U.S","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007261371","display_name":"Jocelyne Fiaux","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]},{"id":"https://openalex.org/I4405255162","display_name":"Institute of Molecular Biology and Biophysics","ror":"https://ror.org/02p702482","country_code":"CH","type":"facility","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088","https://openalex.org/I4405255162"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Jocelyne Fiaux","raw_affiliation_strings":["Institut f\u00fcr Molekularbiologie und Biophysik, Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich, CH-8093 Z\u00fcrich, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut f\u00fcr Molekularbiologie und Biophysik, Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich, CH-8093 Z\u00fcrich, Switzerland","institution_ids":["https://openalex.org/I35440088","https://openalex.org/I4405255162"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036728793","display_name":"Gerhard Wider","orcid":"https://orcid.org/0000-0001-9366-7645","observed_orcids":["https://orcid.org/0000-0001-9366-7645"]},"institutions":[{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]},{"id":"https://openalex.org/I4405255162","display_name":"Institute of Molecular Biology and Biophysics","ror":"https://ror.org/02p702482","country_code":"CH","type":"facility","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088","https://openalex.org/I4405255162"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Gerhard Wider","raw_affiliation_strings":["Institut f\u00fcr Molekularbiologie und Biophysik, Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich, CH-8093 Z\u00fcrich, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut f\u00fcr Molekularbiologie und Biophysik, Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich, CH-8093 Z\u00fcrich, Switzerland","institution_ids":["https://openalex.org/I35440088","https://openalex.org/I4405255162"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034561133","display_name":"Arthur L. Horwich","orcid":"https://orcid.org/0000-0001-9561-8839","observed_orcids":["https://orcid.org/0000-0001-9561-8839"]},"institutions":[{"id":"https://openalex.org/I123431417","display_name":"Scripps Research Institute","ror":"https://ror.org/02dxx6824","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I123431417"]},{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Arthur L. Horwich","raw_affiliation_strings":["Howard Hughes Medical Institute and Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, U.S","The Scripps Research Institute, La Jolla, CA 92037, US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Howard Hughes Medical Institute and Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, U.S","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I32971472"]},{"raw_affiliation_string":"The Scripps Research Institute, La Jolla, CA 92037, US","institution_ids":["https://openalex.org/I123431417"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000254356","display_name":"Kurt W\u00fcthrich A","orcid":"https://orcid.org/0000-0001-8739-6965","observed_orcids":["https://orcid.org/0000-0001-8739-6965","https://orcid.org/0000-0003-2612-6616"]},"institutions":[{"id":"https://openalex.org/I123431417","display_name":"Scripps Research Institute","ror":"https://ror.org/02dxx6824","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I123431417"]},{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]},{"id":"https://openalex.org/I4405255162","display_name":"Institute of Molecular Biology and Biophysics","ror":"https://ror.org/02p702482","country_code":"CH","type":"facility","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088","https://openalex.org/I4405255162"]}],"countries":["CH","US"],"is_corresponding":false,"raw_author_name":"Kurt W\u00fcthrich","raw_affiliation_strings":["Institut f\u00fcr Molekularbiologie und Biophysik, Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich, CH-8093 Z\u00fcrich, Switzerland","The Scripps Research Institute, La Jolla, CA 92037, US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut f\u00fcr Molekularbiologie und Biophysik, Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich, CH-8093 Z\u00fcrich, Switzerland","institution_ids":["https://openalex.org/I35440088","https://openalex.org/I4405255162"]},{"raw_affiliation_string":"The Scripps Research Institute, La Jolla, CA 92037, US","institution_ids":["https://openalex.org/I123431417"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.36106653,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"99","last_page":"104"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10934","display_name":"Heat shock proteins research","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10934","display_name":"Heat shock proteins research","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11809","display_name":"Advanced NMR Techniques and Applications","score":0.009700000286102295,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/groel","display_name":"GroEL","score":0.9639999866485596},{"id":"https://openalex.org/keywords/chaperonin","display_name":"chaperonin","score":0.9290000200271606},{"id":"https://openalex.org/keywords/substrate-proteins","display_name":"substrate proteins","score":0.7699999809265137},{"id":"https://openalex.org/keywords/protein-protein-complex","display_name":"protein-protein complex","score":0.7409999966621399},{"id":"https://openalex.org/keywords/protein-folding","display_name":"protein folding","score":0.621999979019165},{"id":"https://openalex.org/keywords/nmr-spectroscopy","display_name":"NMR spectroscopy","score":0.6809999942779541}],"concepts":[{"id":"https://openalex.org/C85755625","wikidata":"https://www.wikidata.org/wiki/Q24771589","display_name":"Chaperonin","level":3,"score":0.9622932076454163},{"id":"https://openalex.org/C87190427","wikidata":"https://www.wikidata.org/wiki/Q14864994","display_name":"GroEL","level":4,"score":0.9533597230911255},{"id":"https://openalex.org/C2777289219","wikidata":"https://www.wikidata.org/wiki/Q7632154","display_name":"Substrate (aquarium)","level":2,"score":0.5404852628707886},{"id":"https://openalex.org/C8010536","wikidata":"https://www.wikidata.org/wiki/Q160398","display_name":"Crystallography","level":1,"score":0.43356478214263916},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.37848734855651855},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.36496055126190186},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3579663634300232},{"id":"https://openalex.org/C204328495","wikidata":"https://www.wikidata.org/wiki/Q847556","display_name":"Protein folding","level":2,"score":0.3109648823738098},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2726970314979553},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.25537359714508057},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.14068439602851868},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1142/9789811235795_0011","doi":"https://doi.org/10.1142/9789811235795_0011","is_oa":false,"landing_page_url":"https://doi.org/10.1142/9789811235795_0011","pdf_url":null,"source":{"id":"https://openalex.org/S4306464320","display_name":"WORLD SCIENTIFIC eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319815","host_organization_name":"World Scientific","host_organization_lineage":["https://openalex.org/P4310319815"],"host_organization_lineage_names":["World Scientific"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NMR with Biological Macromolecules in Solution","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7208463818","https://openalex.org/W2610545945","https://openalex.org/W4240949291","https://openalex.org/W4205187428","https://openalex.org/W2295495086","https://openalex.org/W2610973978","https://openalex.org/W7018022776","https://openalex.org/W2050315436","https://openalex.org/W2517408588","https://openalex.org/W2069021216"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-17T09:40:24.721904","created_date":"2022-05-12T00:00:00"}