{"id":"https://openalex.org/W4231799786","doi":"https://doi.org/10.2337/figshare.12349781.v1","title":"Brain function differences in children with type 1 diabetes: An fMRI study of working memory","display_name":"Brain function differences in children with type 1 diabetes: An fMRI study of working memory","publication_year":2020,"publication_date":"2020-06-22","ids":{"openalex":"https://openalex.org/W4231799786","doi":"https://doi.org/10.2337/figshare.12349781.v1"},"language":"en","primary_location":{"id":"doi:10.2337/figshare.12349781.v1","doi":"https://doi.org/10.2337/figshare.12349781.v1","is_oa":true,"landing_page_url":"https://doi.org/10.2337/figshare.12349781.v1","pdf_url":null,"source":null,"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"},"volume":null,"type":"other","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.2337/figshare.12349781.v1","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052123970","display_name":"Ada Admin","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ada Admin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030767579","display_name":"Lara C. Foland\u2010Ross","orcid":"https://orcid.org/0000-0001-6358-4566","observed_orcids":["https://orcid.org/0000-0001-6358-4566"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lara C. Foland-Ross","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039089089","display_name":"Gabby Tong","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gabby Tong","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043773015","display_name":"Nelly Mauras","orcid":"https://orcid.org/0000-0003-1175-3852","observed_orcids":["https://orcid.org/0000-0003-1175-3852"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nelly Mauras","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008198696","display_name":"Allison Cato","orcid":"https://orcid.org/0000-0002-9097-3468","observed_orcids":["https://orcid.org/0000-0002-9097-3468"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Allison Cato","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034162263","display_name":"Tandy Aye","orcid":"https://orcid.org/0000-0002-9005-3303","observed_orcids":["https://orcid.org/0000-0002-9005-3303"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tandy Aye","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085112879","display_name":"Michael Tansey","orcid":"https://orcid.org/0000-0002-8157-8423","observed_orcids":["https://orcid.org/0000-0002-8157-8423"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael Tansey","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084201184","display_name":"Neil H. White","orcid":"https://orcid.org/0000-0002-4701-1976","observed_orcids":["https://orcid.org/0000-0002-4701-1976"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Neil H. White","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045100820","display_name":"STUART ALAN WEINZIMER","orcid":"https://orcid.org/0000-0002-7768-5189","observed_orcids":["https://orcid.org/0000-0002-7768-5189"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Stuart A. Weinzimer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084307843","display_name":"KIMBERLY A. ENGLERT","orcid":"https://orcid.org/0000-0002-7886-0516","observed_orcids":["https://orcid.org/0000-0002-7886-0516"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kimberly Englert","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079337389","display_name":"Hanyang Shen","orcid":"https://orcid.org/0000-0003-3273-9777","observed_orcids":["https://orcid.org/0000-0003-3273-9777"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hanyang Shen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043184294","display_name":"Paul K. Mazaika","orcid":"https://orcid.org/0000-0002-9464-6333","observed_orcids":["https://orcid.org/0000-0002-9464-6333"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Paul K. Mazaika","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5046688401","display_name":"Allan L. Reiss","orcid":"https://orcid.org/0000-0002-1979-4942","observed_orcids":["https://orcid.org/0000-0002-1979-4942"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Allan L. Reiss","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.9643999934196472,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.9643999934196472,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10042","display_name":"Neural and Behavioral Psychology Studies","score":0.019700000062584877,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14104","display_name":"Developmental and Educational Neuropsychology","score":0.003800000064074993,"subfield":{"id":"https://openalex.org/subfields/3206","display_name":"Neuropsychology and Physiological Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/type-1-diabetes","display_name":"type 1 diabetes","score":0.9869999885559082},{"id":"https://openalex.org/keywords/children","display_name":"children","score":0.8690000176429749},{"id":"https://openalex.org/keywords/working-memory","display_name":"working memory","score":0.9739999771118164},{"id":"https://openalex.org/keywords/n-back-task","display_name":"n-back task","score":0.6800000071525574},{"id":"https://openalex.org/keywords/brain-activation","display_name":"brain activation","score":0.6840000152587891},{"id":"https://openalex.org/keywords/compensatory-mechanisms","display_name":"compensatory mechanisms","score":0.5400000214576721},{"id":"https://openalex.org/keywords/age-at-diagnosis","display_name":"age at diagnosis","score":0.8240000009536743},{"id":"https://openalex.org/keywords/glycemic-control","display_name":"glycemic control","score":0.6930000185966492},{"id":"https://openalex.org/keywords/brain-development","display_name":"brain development","score":0.7459999918937683},{"id":"https://openalex.org/keywords/dysglycemia","display_name":"dysglycemia","score":0.7730000019073486},{"id":"https://openalex.org/keywords/frontoparietal-cortex","display_name":"frontoparietal cortex","score":0.906000018119812},{"id":"https://openalex.org/keywords/caudate-nucleus","display_name":"caudate nucleus","score":0.8840000033378601},{"id":"https://openalex.org/keywords/cerebellum","display_name":"cerebellum","score":1.0}],"concepts":[{"id":"https://openalex.org/C21963081","wikidata":"https://www.wikidata.org/wiki/Q11337567","display_name":"Working memory","level":3,"score":0.8604996204376221},{"id":"https://openalex.org/C2780473172","wikidata":"https://www.wikidata.org/wiki/Q5572518","display_name":"Glycemic","level":3,"score":0.5353760123252869},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5002200603485107},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.48535171151161194},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4821564555168152},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.47155284881591797},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.42990192770957947},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.351570188999176},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.2989232838153839},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.16559720039367676},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.15083909034729004}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.2337/figshare.12349781.v1","doi":"https://doi.org/10.2337/figshare.12349781.v1","is_oa":true,"landing_page_url":"https://doi.org/10.2337/figshare.12349781.v1","pdf_url":null,"source":null,"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.2337/figshare.12349781.v1","doi":"https://doi.org/10.2337/figshare.12349781.v1","is_oa":true,"landing_page_url":"https://doi.org/10.2337/figshare.12349781.v1","pdf_url":null,"source":null,"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3032422865","https://openalex.org/W2991962582","https://openalex.org/W7097772909","https://openalex.org/W1592762266","https://openalex.org/W4254703849","https://openalex.org/W2948298110","https://openalex.org/W2622724911","https://openalex.org/W2153793093","https://openalex.org/W2261840464","https://openalex.org/W2793737667"],"abstract_inverted_index":{"Glucose":[0],"is":[1],"a":[2,61,117,159,190],"primary":[3],"fuel":[4],"source":[5],"to":[6,104,165],"the":[7,10,85,100,135],"brain,":[8],"yet":[9],"influence":[11],"of":[12,112,148,192],"dysglycemia":[13],"on":[14,99],"neurodevelopment":[15],"in":[16,31,70,119,134,163],"children":[17,33,48,93,173],"with":[18,34,76,94,121,138,144,174],"type":[19,35],"1":[20,36],"diabetes":[21,37,50,95,136],"remains":[22],"unclear.":[23],"We":[24],"examined":[25],"brain":[26],"activation":[27,73,113,120],"using":[28],"functional":[29],"MRI":[30],"80":[32],"(mean":[38],"age":[39,53,147],"\u00b1":[40],"SD,":[41],"11.5\u00b11.8":[42],"years;":[43,55],"46%":[44],"female)":[45,57],"and":[46,89,143,170],"47":[47],"without":[49],"(\u201ccontrol\u201d,":[51],"mean":[52],"11.8\u00b11.5":[54],"51%":[56],"as":[58,107,109,158,189],"they":[59],"performed":[60],"visuospatial":[62],"working":[63,78,123,140,167],"memory":[64,79,124,141,168],"(N-back)":[65],"task.":[66],"Results":[67],"indicated":[68,128],"that":[69,129,153,172,183],"both":[71],"groups,":[72,92],"scaled":[74],"positively":[75],"increasing":[77],"load":[80],"across":[81],"many":[82],"areas,":[83],"including":[84],"frontoparietal":[86],"cortex,":[87],"caudate":[88],"cerebellum.":[90],"Between":[91],"exhibited":[96],"reduced":[97],"performance":[98],"N-back":[101],"task":[102],"relative":[103],"control":[105,195],"children,":[106],"well":[108],"greater":[110,116,130],"modulation":[111,131,155],"(i.e.,":[114],"showed":[115],"increase":[118],"higher":[122],"load).":[125],"Post-hoc":[126],"analyses":[127],"was":[132],"associated":[133],"group":[137],"better":[139],"function":[142,191],"an":[145,175],"earlier":[146,176],"diagnosis.":[149],"These":[150],"findings":[151],"suggest":[152],"increased":[154],"may":[156],"occur":[157],"compensatory":[160],"mechanism,":[161],"helping":[162],"part":[164],"preserve":[166],"ability,":[169],"further,":[171],"onset":[177],"require":[178],"additional":[179],"compensation.":[180],"Future":[181],"studies":[182],"test":[184],"whether":[185],"these":[186],"patterns":[187],"change":[188],"improved":[193],"glycemic":[194],"are":[196],"warranted.":[197]},"counts_by_year":[],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2022-05-12T00:00:00"}