{"id":"https://openalex.org/W4230752000","doi":"https://doi.org/10.1002/14651858.cd005019.pub3","title":"HMG CoA reductase inhibitors (statins) for kidney transplant recipients","display_name":"HMG CoA reductase inhibitors (statins) for kidney transplant recipients","publication_year":2009,"publication_date":"2009-04-15","ids":{"openalex":"https://openalex.org/W4230752000","doi":"https://doi.org/10.1002/14651858.cd005019.pub3","pmid":"https://pubmed.ncbi.nlm.nih.gov/19370615"},"language":"en","primary_location":{"id":"doi:10.1002/14651858.cd005019.pub3","doi":"https://doi.org/10.1002/14651858.cd005019.pub3","is_oa":false,"landing_page_url":"https://doi.org/10.1002/14651858.cd005019.pub3","pdf_url":null,"source":{"id":"https://openalex.org/S4210172715","display_name":"Cochrane Database of Systematic Reviews","issn_l":"1361-6137","issn":["1361-6137","1464-780X","1465-184X","1465-1858","1469-493X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-1","jufo-2","ki-jl-2","medline","norway-1","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cochrane Database of Systematic Reviews","raw_type":"reference-entry"},"volume":null,"type":"reference-entry","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088788555","display_name":"Sankar Dass Navaneethan","orcid":"https://orcid.org/0000-0002-4953-7795","observed_orcids":["https://orcid.org/0000-0002-4953-7795"]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]},{"id":"https://openalex.org/I4405285950","display_name":"Glickman Urological Institute","ror":"https://ror.org/00rxngd38","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750","https://openalex.org/I4405285950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sankar D Navaneethan","raw_affiliation_strings":["Department of Nephrology and Hypertension, Glickman Urological and Kidney institute, Cleveland Clinic, Cleveland, OH 44195, USA. navanes@ccf.org","Glickman Urological and Kidney institute, Cleveland Clinic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology and Hypertension, Glickman Urological and Kidney institute, Cleveland Clinic, Cleveland, OH 44195, USA. navanes@ccf.org","institution_ids":["https://openalex.org/I1316902750","https://openalex.org/I4405285950"]},{"raw_affiliation_string":"Glickman Urological and Kidney institute, Cleveland Clinic","institution_ids":["https://openalex.org/I1316902750","https://openalex.org/I4405285950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027520502","display_name":"Vlado Perkovic","orcid":"https://orcid.org/0000-0002-4257-7620","observed_orcids":["https://orcid.org/0000-0002-4257-7620"]},"institutions":[{"id":"https://openalex.org/I183874623","display_name":"The George Institute for Global Health","ror":"https://ror.org/04h0zjx60","country_code":"GB","type":"facility","lineage":["https://openalex.org/I183874623","https://openalex.org/I4210110309"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Vlado Perkovic","raw_affiliation_strings":["The George Institute for International Health"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The George Institute for International Health","institution_ids":["https://openalex.org/I183874623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043394711","display_name":"David Wayne Johnson","orcid":"https://orcid.org/0000-0001-5491-3460","observed_orcids":["https://orcid.org/0000-0001-5491-3460","https://orcid.org/0000-0001-8453-7849","https://orcid.org/0000-0001-6932-2460"]},"institutions":[{"id":"https://openalex.org/I2801814493","display_name":"Princess Alexandra Hospital","ror":"https://ror.org/04mqb0968","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1302211766","https://openalex.org/I2801244131","https://openalex.org/I2801814493","https://openalex.org/I4210089726"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"David W Johnson","raw_affiliation_strings":["Princess Alexandra Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Princess Alexandra Hospital","institution_ids":["https://openalex.org/I2801814493"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113952270","display_name":"Sagar U Nigwekar","orcid":"https://orcid.org/0000-0002-6750-0072","observed_orcids":["https://orcid.org/0000-0002-6750-0072"]},"institutions":[{"id":"https://openalex.org/I28792581","display_name":"University of Rochester Medicine","ror":"https://ror.org/00trqv719","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I28792581","https://openalex.org/I5388228"]},{"id":"https://openalex.org/I5388228","display_name":"University of Rochester","ror":"https://ror.org/022kthw22","country_code":"US","type":"education","lineage":["https://openalex.org/I5388228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sagar U Nigwekar","raw_affiliation_strings":["University of Rochester School of Medicine and Dentistry"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Rochester School of Medicine and Dentistry","institution_ids":["https://openalex.org/I28792581","https://openalex.org/I5388228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038938109","display_name":"Jonathan C. Craig","orcid":"https://orcid.org/0000-0002-2548-4035","observed_orcids":["https://orcid.org/0000-0002-2548-4035"]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Jonathan C Craig","raw_affiliation_strings":["School of Public Health, The University of Sydney"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Public Health, The University of Sydney","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5080193257","display_name":"Giovanni FM Strippoli","orcid":"https://orcid.org/0000-0002-6936-0616","observed_orcids":["https://orcid.org/0000-0002-6936-0616"]},"institutions":[{"id":"https://openalex.org/I2802384191","display_name":"Children's Hospital at Westmead","ror":"https://ror.org/05k0s5494","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2802384191"]},{"id":"https://openalex.org/I2803024705","display_name":"Westmead Hospital","ror":"https://ror.org/04gp5yv64","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2803024705","https://openalex.org/I4405259172"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Giovanni FM Strippoli","raw_affiliation_strings":["The Children's Hospital at Westmead"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Children's Hospital at Westmead","institution_ids":["https://openalex.org/I2802384191","https://openalex.org/I2803024705"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":9,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5100,"currency":"USD","value_usd":5100},"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":46,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":"2","first_page":"CD005019","last_page":"CD005019"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.7660999894142151,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.7660999894142151,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":0.22190000116825104,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12465","display_name":"Cancer, Lipids, and Metabolism","score":0.0038999998942017555,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/statins","display_name":"statins","score":0.984000027179718},{"id":"https://openalex.org/keywords/kidney-transplant-recipients","display_name":"kidney transplant recipients","score":0.9509999752044678},{"id":"https://openalex.org/keywords/cardiovascular-mortality","display_name":"cardiovascular mortality","score":0.7289999723434448},{"id":"https://openalex.org/keywords/dyslipidemia","display_name":"dyslipidemia","score":0.8379999995231628},{"id":"https://openalex.org/keywords/lipid-lowering-therapy","display_name":"lipid-lowering therapy","score":0.7170000076293945},{"id":"https://openalex.org/keywords/ldl-cholesterol","display_name":"LDL cholesterol","score":0.628000020980835},{"id":"https://openalex.org/keywords/triglycerides","display_name":"triglycerides","score":0.949999988079071},{"id":"https://openalex.org/keywords/total-cholesterol","display_name":"total cholesterol","score":0.6430000066757202},{"id":"https://openalex.org/keywords/allograft-rejection","display_name":"allograft rejection","score":0.7689999938011169},{"id":"https://openalex.org/keywords/rhabdomyolysis","display_name":"rhabdomyolysis","score":0.9229999780654907},{"id":"https://openalex.org/keywords/liver-enzymes","display_name":"liver enzymes","score":0.7200000286102295},{"id":"https://openalex.org/keywords/renal-outcomes","display_name":"renal outcomes","score":0.7929999828338623},{"id":"https://openalex.org/keywords/cardiovascular-events","display_name":"cardiovascular events","score":0.5239999890327454},{"id":"https://openalex.org/keywords/drug-safety","display_name":"drug safety","score":0.36500000953674316},{"id":"https://openalex.org/keywords/transplant-immunosuppression","display_name":"transplant immunosuppression","score":0.6179999709129333},{"id":"https://openalex.org/keywords/statin-drug-interactions","display_name":"statin-drug interactions","score":0.47200000286102295}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9086422920227051},{"id":"https://openalex.org/C82789193","wikidata":"https://www.wikidata.org/wiki/Q2142611","display_name":"Relative risk","level":3,"score":0.6722827553749084},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.6566675305366516},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6560391783714294},{"id":"https://openalex.org/C2776839432","wikidata":"https://www.wikidata.org/wiki/Q954845","display_name":"Statin","level":2,"score":0.5786135196685791},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5341749787330627},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.5223963260650635},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.502713680267334},{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.48602062463760376},{"id":"https://openalex.org/C2777482532","wikidata":"https://www.wikidata.org/wiki/Q668093","display_name":"Atorvastatin","level":2,"score":0.4747886061668396},{"id":"https://openalex.org/C2779379848","wikidata":"https://www.wikidata.org/wiki/Q917069","display_name":"Rhabdomyolysis","level":2,"score":0.4605860114097595},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.42511266469955444},{"id":"https://openalex.org/C2780303639","wikidata":"https://www.wikidata.org/wiki/Q740909","display_name":"Kidney transplantation","level":3,"score":0.41753169894218445},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.33699044585227966},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.06441539525985718},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000960","descriptor_name":"Hypolipidemic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D006084","descriptor_name":"Graft Rejection","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014280","descriptor_name":"Triglycerides","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016030","descriptor_name":"Kidney Transplantation","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019161","descriptor_name":"Hydroxymethylglutaryl-CoA Reductase Inhibitors","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D019161","descriptor_name":"Hydroxymethylglutaryl-CoA Reductase Inhibitors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1002/14651858.cd005019.pub3","doi":"https://doi.org/10.1002/14651858.cd005019.pub3","is_oa":false,"landing_page_url":"https://doi.org/10.1002/14651858.cd005019.pub3","pdf_url":null,"source":{"id":"https://openalex.org/S4210172715","display_name":"Cochrane Database of Systematic Reviews","issn_l":"1361-6137","issn":["1361-6137","1464-780X","1465-184X","1465-1858","1469-493X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-1","jufo-2","ki-jl-2","medline","norway-1","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cochrane Database of Systematic Reviews","raw_type":"reference-entry"},{"id":"pmid:19370615","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19370615","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Cochrane database of systematic reviews","raw_type":"Journal Article"},{"id":"pmh:oai:ricerca.uniba.it:11586/242909","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11586/242909","pdf_url":null,"source":{"id":"https://openalex.org/S4377196296","display_name":"CINECA IRIS Institutional Research Information System (University of Bari Aldo Moro)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I5561750","host_organization_name":"University of Bari Aldo Moro","host_organization_lineage":["https://openalex.org/I5561750"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8799999952316284}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":66,"referenced_works":["https://openalex.org/W124886375","https://openalex.org/W189373028","https://openalex.org/W1500963439","https://openalex.org/W1502524639","https://openalex.org/W1573777214","https://openalex.org/W1891715432","https://openalex.org/W1903870809","https://openalex.org/W1939259427","https://openalex.org/W1960912206","https://openalex.org/W1975705705","https://openalex.org/W1979086297","https://openalex.org/W1994930409","https://openalex.org/W1999187183","https://openalex.org/W2001285551","https://openalex.org/W2004330500","https://openalex.org/W2008797334","https://openalex.org/W2011010559","https://openalex.org/W2011103783","https://openalex.org/W2011377445","https://openalex.org/W2012821845","https://openalex.org/W2013467357","https://openalex.org/W2013755756","https://openalex.org/W2013800720","https://openalex.org/W2016265356","https://openalex.org/W2024595878","https://openalex.org/W2028056878","https://openalex.org/W2031185570","https://openalex.org/W2033471268","https://openalex.org/W2035811858","https://openalex.org/W2037198165","https://openalex.org/W2040904160","https://openalex.org/W2052989238","https://openalex.org/W2060774684","https://openalex.org/W2061190448","https://openalex.org/W2064649898","https://openalex.org/W2067677131","https://openalex.org/W2069617483","https://openalex.org/W2084126045","https://openalex.org/W2088865411","https://openalex.org/W2092674082","https://openalex.org/W2093758594","https://openalex.org/W2097526694","https://openalex.org/W2107943520","https://openalex.org/W2109355182","https://openalex.org/W2111593137","https://openalex.org/W2112009673","https://openalex.org/W2125342975","https://openalex.org/W2127668399","https://openalex.org/W2132802195","https://openalex.org/W2137914533","https://openalex.org/W2138464181","https://openalex.org/W2141137365","https://openalex.org/W2155598961","https://openalex.org/W2156880046","https://openalex.org/W2162050086","https://openalex.org/W2166121680","https://openalex.org/W2284948208","https://openalex.org/W2325308994","https://openalex.org/W2327533441","https://openalex.org/W2331937676","https://openalex.org/W2408713689","https://openalex.org/W2487377689","https://openalex.org/W2992458177","https://openalex.org/W4239339499","https://openalex.org/W4249377962","https://openalex.org/W4300888082"],"related_works":["https://openalex.org/W4402460698","https://openalex.org/W4397042256","https://openalex.org/W4323653683","https://openalex.org/W7154835718","https://openalex.org/W4391550465","https://openalex.org/W7096024474","https://openalex.org/W2138464181","https://openalex.org/W4391174323","https://openalex.org/W2132802195","https://openalex.org/W2007607468"],"abstract_inverted_index":{"BACKGROUND:":[0],"Cardiovascular":[1],"deaths":[2,8],"account":[3],"for":[4,132,141,150,356],"the":[5,34,47,69,126,236,245,307,361,371,382],"majority":[6],"of":[7,51,73,82,159,210,247,256,309,360,374],"in":[9,25,33,59,104,208,306,345,381,391],"kidney":[10,26,60,105,346,392],"transplant":[11,27,61,106,347,393],"recipients":[12],"and":[13,49,56,77,84,93,118,146,161,222,287,327,339,378,384],"dyslipidaemia":[14],"contributes":[15],"significantly":[16,253,336],"to":[17,187,202,220,233,243,271,285,299,318,341],"their":[18,30,40],"cardiovascular":[19,211,224,343,379],"disease.":[20],"Statins":[21,335],"are":[22,389],"widely":[23],"used":[24],"patients":[28],"given":[29],"established":[31],"benefits":[32,48],"general":[35,383],"population,":[36],"however":[37,235],"evidence":[38],"favouring":[39],"use":[41,246],"is":[42],"lacking.":[43],"OBJECTIVES:":[44],"To":[45],"assess":[46],"harms":[50],"statin":[52,182],"therapy":[53],"on":[54,322,376],"mortality":[55,194,212,357,380],"renal":[57],"outcomes":[58,143,152],"recipients.":[62,107],"SEARCH":[63],"STRATEGY:":[64],"We":[65],"searched":[66,79],"MEDLINE,":[67],"EMBASE,":[68],"Cochrane":[70],"Central":[71],"Register":[72],"Controlled":[74],"Trials":[75],"(CENTRAL),":[76],"hand":[78],"reference":[80],"lists":[81],"articles":[83],"scientific":[85],"proceedings.":[86],"SELECTION":[87],"CRITERIA:":[88],"Randomised":[89],"controlled":[90],"trials":[91],"(RCTs)":[92],"quasi-RCTs":[94],"comparing":[95,175],"statins":[96,103,176,189,207,248,375],"with":[97,164,251],"placebo,":[98,188,244],"no":[99,303,328,350],"treatment":[100,257],"or":[101,180],"other":[102],"DATA":[108],"COLLECTION":[109],"AND":[110],"ANALYSIS:":[111],"Two":[112],"authors":[113],"independently":[114],"assessed":[115],"study":[116,162],"quality":[117],"extracted":[119],"data.":[120],"Statistical":[121],"analyses":[122],"were":[123,135,184,238],"performed":[124],"using":[125],"random":[127],"effects":[128],"model":[129],"after":[130],"testing":[131],"heterogeneity.":[133],"Results":[134],"expressed":[136],"as":[137],"mean":[138],"difference":[139,305],"(MD)":[140],"continuous":[142],"(lipid":[144],"parameters)":[145],"risk":[147,308],"ratio":[148],"(RR)":[149],"dichotomous":[151],"(mortality,":[153],"allograft":[154],"rejection,":[155],"liver":[156],"enzymes,":[157],"occurrence":[158],"rhabdomyolysis":[160],"withdrawal)":[163],"95%":[165,199,217,230,268,282,296,316],"confidence":[166],"intervals":[167],"(CI).":[168],"MAIN":[169],"RESULTS:":[170],"Sixteen":[171],"studies":[172,388],"(3229":[173],"patients)":[174],"versus":[177],"placebo":[178],"(15)":[179],"another":[181],"(1)":[183],"included.":[185],"Compared":[186,242],"did":[190],"not":[191,239],"decrease":[192],"all-cause":[193,377],"(14":[195],"studies:":[196,214,262,276,290,313],"RR":[197,215,228,314],"1.30,":[198],"CI":[200,218,231,269,283,297],"0.54":[201],"3.12).":[203],"Point":[204],"estimates":[205],"favoured":[206],"terms":[209],"(13":[213],"0.68,":[216],"0.46":[219],"1.03)":[221],"non-fatal":[223],"events":[225,344],"(1":[226],"study:":[227],"0.70,":[229],"0.48":[232],"1.01),":[234],"results":[237],"statistically":[240],"significant.":[241],"was":[249,302,325,331,363],"associated":[250],"a":[252],"lower":[254],"end":[255],"average":[258],"total":[259],"cholesterol":[260,274],"(10":[261,275,289],"MD":[263,277,291],"-42.33":[264],"mg/dL":[265,279,293],"(1.26":[266],"mmol/L),":[267,281,295],"-53.02":[270],"-31.64),":[272],"LDL":[273],"-46.15":[278],"(1.19":[280],"-55.97":[284],"-36.33)":[286],"triglycerides":[288],"-25.46":[292],"(0.26":[294],"-33.95":[298],"16.9).":[300],"There":[301],"significant":[304,372],"acute":[310],"rejection":[311,324],"(5":[312],"0.61;":[315],"C.I.0.32":[317],"1.16.)":[319],"No":[320],"data":[321,362],"chronic":[323],"available":[326],"major":[329],"toxicity":[330],"noted.":[332],"AUTHORS'":[333],"CONCLUSIONS:":[334],"reduced":[337],"hyperlipidaemia":[338],"tended":[340],"reduce":[342],"recipients,":[348],"but":[349],"effect":[351],"has":[352],"yet":[353],"been":[354],"demonstrated":[355],"outcomes.":[358],"Most":[359],"derived":[364],"from":[365],"one":[366],"large":[367],"long-term":[368],"study.":[369],"Considering":[370],"impact":[373],"predialysis":[385],"populations,":[386],"more":[387],"needed":[390],"patients.":[394]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":4},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":7}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2022-05-11T00:00:00"}