{"id":"https://openalex.org/W4229895997","doi":"https://doi.org/10.1007/978-3-319-19674-9_29","title":"Retinoblastoma","display_name":"Retinoblastoma","publication_year":2016,"publication_date":"2016-01-01","ids":{"openalex":"https://openalex.org/W4229895997","doi":"https://doi.org/10.1007/978-3-319-19674-9_29"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-319-19674-9_29","doi":"https://doi.org/10.1007/978-3-319-19674-9_29","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-319-19674-9_29","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Pathology in Clinical Practice","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4230504278","display_name":"Molecular Pathology in Clinical Practice"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082184763","display_name":"Arupa A. Ganguly","orcid":"https://orcid.org/0000-0003-4527-3216","observed_orcids":["https://orcid.org/0000-0003-4527-3216"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Arupa Ganguly","raw_affiliation_strings":["Department of Genetics, Perelman School of Medicine, University of Pennsylvania, 415 Curie Boulevard, Room 500, Philadelphia, PA, 19104, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Perelman School of Medicine, University of Pennsylvania, 415 Curie Boulevard, Room 500, Philadelphia, PA, 19104, USA","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100352002","display_name":"Zhao Chen","orcid":"https://orcid.org/0000-0002-5782-3329","observed_orcids":["https://orcid.org/0000-0002-5782-3329"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhao Chen","raw_affiliation_strings":["Department of Genetics, Perelman School of Medicine, University of Pennsylvania, 415 Curie Boulevard, Room 500, Philadelphia, PA, 19104, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Perelman School of Medicine, University of Pennsylvania, 415 Curie Boulevard, Room 500, Philadelphia, PA, 19104, USA","institution_ids":["https://openalex.org/I79576946"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5082184763"],"corresponding_institution_ids":["https://openalex.org/I79576946"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.57636656,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"385","last_page":"392"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11328","display_name":"Ocular Oncology and Treatments","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11328","display_name":"Ocular Oncology and Treatments","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12989","display_name":"Ocular Disorders and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/retinoblastoma","display_name":"retinoblastoma","score":1.0},{"id":"https://openalex.org/keywords/germline-mutations","display_name":"germline mutations","score":0.9549999833106995},{"id":"https://openalex.org/keywords/hereditary-retinoblastoma","display_name":"hereditary retinoblastoma","score":0.8769999742507935},{"id":"https://openalex.org/keywords/unilateral-retinoblastoma","display_name":"unilateral retinoblastoma","score":0.8659999966621399},{"id":"https://openalex.org/keywords/biallelic-inactivation","display_name":"biallelic inactivation","score":0.8009999990463257},{"id":"https://openalex.org/keywords/promoter-methylation","display_name":"promoter methylation","score":0.7580000162124634},{"id":"https://openalex.org/keywords/mosaicism","display_name":"mosaicism","score":0.734000027179718},{"id":"https://openalex.org/keywords/mycn-amplification","display_name":"MYCN amplification","score":0.8539999723434448},{"id":"https://openalex.org/keywords/genetic-diagnosis","display_name":"genetic diagnosis","score":0.5450000166893005}],"concepts":[{"id":"https://openalex.org/C2776577112","wikidata":"https://www.wikidata.org/wiki/Q500695","display_name":"Retinoblastoma","level":3,"score":0.9074513912200928},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6184584498405457},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5018880367279053},{"id":"https://openalex.org/C109825262","wikidata":"https://www.wikidata.org/wiki/Q1139164","display_name":"Germline","level":3,"score":0.4921237826347351},{"id":"https://openalex.org/C13514818","wikidata":"https://www.wikidata.org/wiki/Q5552256","display_name":"Germline mutation","level":4,"score":0.4723473787307739},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4559205174446106},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4454004466533661},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.373749703168869},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.3403659164905548}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-3-319-19674-9_29","doi":"https://doi.org/10.1007/978-3-319-19674-9_29","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-319-19674-9_29","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Pathology in Clinical Practice","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":56,"referenced_works":["https://openalex.org/W201820481","https://openalex.org/W1741394036","https://openalex.org/W1865184513","https://openalex.org/W1922504735","https://openalex.org/W1964526999","https://openalex.org/W1979364668","https://openalex.org/W1981792973","https://openalex.org/W1982411289","https://openalex.org/W1982452892","https://openalex.org/W1982532969","https://openalex.org/W1990687371","https://openalex.org/W1995692004","https://openalex.org/W2017050934","https://openalex.org/W2019513601","https://openalex.org/W2022507045","https://openalex.org/W2026362568","https://openalex.org/W2026996045","https://openalex.org/W2034269086","https://openalex.org/W2039540524","https://openalex.org/W2040301123","https://openalex.org/W2046651088","https://openalex.org/W2047586634","https://openalex.org/W2049133549","https://openalex.org/W2051293486","https://openalex.org/W2051863115","https://openalex.org/W2062123110","https://openalex.org/W2065304488","https://openalex.org/W2069558552","https://openalex.org/W2071193398","https://openalex.org/W2071333117","https://openalex.org/W2072142627","https://openalex.org/W2077227726","https://openalex.org/W2077858999","https://openalex.org/W2078218951","https://openalex.org/W2079941948","https://openalex.org/W2084171824","https://openalex.org/W2087625745","https://openalex.org/W2099742439","https://openalex.org/W2117692326","https://openalex.org/W2123538192","https://openalex.org/W2124966703","https://openalex.org/W2125169096","https://openalex.org/W2131401451","https://openalex.org/W2132888849","https://openalex.org/W2140107851","https://openalex.org/W2142877023","https://openalex.org/W2152472434","https://openalex.org/W2154194316","https://openalex.org/W2154962291","https://openalex.org/W2162139554","https://openalex.org/W2164026919","https://openalex.org/W2165981075","https://openalex.org/W2406223392","https://openalex.org/W4240107562","https://openalex.org/W4256483454","https://openalex.org/W4299429547"],"related_works":["https://openalex.org/W2024294030","https://openalex.org/W2198837695","https://openalex.org/W2780727274","https://openalex.org/W2608139427","https://openalex.org/W2309826625","https://openalex.org/W4285362409","https://openalex.org/W867583732","https://openalex.org/W2078416547","https://openalex.org/W2777053786","https://openalex.org/W1965906281"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2022-05-11T00:00:00"}