{"id":"https://openalex.org/W4229787828","doi":"https://doi.org/10.7324/japs.2019.90211","title":"RP-HPLC method for determination of norethindrone in dissolution media and application to study release from a controlled release nanoparticulate liquid medicated formulation","display_name":"RP-HPLC method for determination of norethindrone in dissolution media and application to study release from a controlled release nanoparticulate liquid medicated formulation","publication_year":2019,"publication_date":"2019-02-01","ids":{"openalex":"https://openalex.org/W4229787828","doi":"https://doi.org/10.7324/japs.2019.90211"},"language":"en","primary_location":{"id":"doi:10.7324/japs.2019.90211","doi":"https://doi.org/10.7324/japs.2019.90211","is_oa":true,"landing_page_url":"https://doi.org/10.7324/japs.2019.90211","pdf_url":"https://www.japsonline.com/admin/php/uploads/2844_pdf.pdf","source":{"id":"https://openalex.org/S2764844132","display_name":"Journal of Applied Pharmaceutical Science","issn_l":"2231-3354","issn":["2231-3354"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4327876862","host_organization_name":"Open Science Publishers LLP","host_organization_lineage":["https://openalex.org/P4327876862"],"host_organization_lineage_names":["Open Science Publishers LLP"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Applied Pharmaceutical Science","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.japsonline.com/admin/php/uploads/2844_pdf.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5080665021","display_name":"Suhair S. Al\u2010Nimry","orcid":"https://orcid.org/0000-0002-7164-0158","observed_orcids":["https://orcid.org/0000-0002-7164-0158"]},"institutions":[{"id":"https://openalex.org/I156983542","display_name":"Jordan University of Science and Technology","ror":"https://ror.org/03y8mtb59","country_code":"JO","type":"education","lineage":["https://openalex.org/I156983542"]}],"countries":["JO"],"is_corresponding":false,"raw_author_name":"Suhair S. Al-Nimry","raw_affiliation_strings":["Corresponding Author Suhair S. Al-Nimry, Pharmaceutical Technology Department, Jordan University of Science and Technology, Irbid, Jordan","Pharmaceutical Technology Department, Jordan University of Science and Technology, Irbid, Jordan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Corresponding Author Suhair S. Al-Nimry, Pharmaceutical Technology Department, Jordan University of Science and Technology, Irbid, Jordan","institution_ids":["https://openalex.org/I156983542"]},{"raw_affiliation_string":"Pharmaceutical Technology Department, Jordan University of Science and Technology, Irbid, Jordan","institution_ids":["https://openalex.org/I156983542"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087907648","display_name":"Bashar Al-Taani","orcid":"https://orcid.org/0000-0002-8658-4830","observed_orcids":["https://orcid.org/0000-0002-8658-4830"]},"institutions":[{"id":"https://openalex.org/I156983542","display_name":"Jordan University of Science and Technology","ror":"https://ror.org/03y8mtb59","country_code":"JO","type":"education","lineage":["https://openalex.org/I156983542"]}],"countries":["JO"],"is_corresponding":false,"raw_author_name":"Bashar M. Altaani","raw_affiliation_strings":["Pharmaceutical Technology Department, Jordan University of Science and Technology, Irbid, Jordan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmaceutical Technology Department, Jordan University of Science and Technology, Irbid, Jordan","institution_ids":["https://openalex.org/I156983542"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002439324","display_name":"Razan H. Haddad","orcid":"https://orcid.org/0000-0001-5437-6394","observed_orcids":["https://orcid.org/0000-0001-5437-6394"]},"institutions":[{"id":"https://openalex.org/I156983542","display_name":"Jordan University of Science and Technology","ror":"https://ror.org/03y8mtb59","country_code":"JO","type":"education","lineage":["https://openalex.org/I156983542"]}],"countries":["JO"],"is_corresponding":false,"raw_author_name":"Razan H. Haddad","raw_affiliation_strings":["Pharmaceutical Technology Department, Jordan University of Science and Technology, Irbid, Jordan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmaceutical Technology Department, Jordan University of Science and Technology, Irbid, Jordan","institution_ids":["https://openalex.org/I156983542"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I156983542"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"9","issue":"2","first_page":"079","last_page":"086"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11460","display_name":"Analytical Methods in Pharmaceuticals","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11460","display_name":"Analytical Methods in Pharmaceuticals","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10908","display_name":"Analytical Chemistry and Chromatography","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/norethisterone","display_name":"norethisterone","score":1.0},{"id":"https://openalex.org/keywords/rp-hplc-method-development","display_name":"RP-HPLC method development","score":0.8820000290870667},{"id":"https://openalex.org/keywords/method-validation","display_name":"method validation","score":0.8709999918937683},{"id":"https://openalex.org/keywords/dissolution-medium","display_name":"dissolution media","score":0.8840000033378601},{"id":"https://openalex.org/keywords/in-vitro-drug-release","display_name":"in vitro drug release","score":0.8209999799728394},{"id":"https://openalex.org/keywords/controlled-release","display_name":"controlled release","score":0.7400000095367432},{"id":"https://openalex.org/keywords/sustained-release","display_name":"sustained drug release","score":0.7670000195503235},{"id":"https://openalex.org/keywords/nanoemulsions","display_name":"nanoemulsions","score":0.996999979019165},{"id":"https://openalex.org/keywords/zero-order-kinetics","display_name":"zero-order kinetics","score":0.6420000195503235}],"concepts":[{"id":"https://openalex.org/C88380143","wikidata":"https://www.wikidata.org/wiki/Q416674","display_name":"Dissolution","level":2,"score":0.8084689378738403},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.7245226502418518},{"id":"https://openalex.org/C179998833","wikidata":"https://www.wikidata.org/wiki/Q381233","display_name":"High-performance liquid chromatography","level":2,"score":0.5501089096069336},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5257685780525208},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.05809211730957031}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.7324/japs.2019.90211","doi":"https://doi.org/10.7324/japs.2019.90211","is_oa":true,"landing_page_url":"https://doi.org/10.7324/japs.2019.90211","pdf_url":"https://www.japsonline.com/admin/php/uploads/2844_pdf.pdf","source":{"id":"https://openalex.org/S2764844132","display_name":"Journal of Applied Pharmaceutical Science","issn_l":"2231-3354","issn":["2231-3354"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4327876862","host_organization_name":"Open Science Publishers LLP","host_organization_lineage":["https://openalex.org/P4327876862"],"host_organization_lineage_names":["Open Science Publishers LLP"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Applied Pharmaceutical Science","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.7324/japs.2019.90211","doi":"https://doi.org/10.7324/japs.2019.90211","is_oa":true,"landing_page_url":"https://doi.org/10.7324/japs.2019.90211","pdf_url":"https://www.japsonline.com/admin/php/uploads/2844_pdf.pdf","source":{"id":"https://openalex.org/S2764844132","display_name":"Journal of Applied Pharmaceutical Science","issn_l":"2231-3354","issn":["2231-3354"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4327876862","host_organization_name":"Open Science Publishers LLP","host_organization_lineage":["https://openalex.org/P4327876862"],"host_organization_lineage_names":["Open Science Publishers LLP"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Applied Pharmaceutical Science","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.504800021648407}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322303","display_name":"Jordan University of Science and Technology","ror":"https://ror.org/03y8mtb59"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4229787828.pdf","grobid_xml":"https://content.openalex.org/works/W4229787828.grobid-xml"},"referenced_works_count":16,"referenced_works":["https://openalex.org/W748375686","https://openalex.org/W1993636240","https://openalex.org/W2001764660","https://openalex.org/W2006145493","https://openalex.org/W2011707447","https://openalex.org/W2063285403","https://openalex.org/W2100741206","https://openalex.org/W2104687197","https://openalex.org/W2128373400","https://openalex.org/W2595888264","https://openalex.org/W2909565437","https://openalex.org/W2946720800","https://openalex.org/W2991820805","https://openalex.org/W4234578874","https://openalex.org/W4239810836","https://openalex.org/W7149520812"],"related_works":["https://openalex.org/W4220700719","https://openalex.org/W3113840471","https://openalex.org/W3180439853","https://openalex.org/W2226667752","https://openalex.org/W2743212878","https://openalex.org/W2575757180","https://openalex.org/W65001448","https://openalex.org/W2378947002","https://openalex.org/W2023724749","https://openalex.org/W2186377607"],"abstract_inverted_index":{"Several":[0],"methods":[1,9],"are":[2,10],"available":[3],"for":[4,33],"the":[5,34,79,82,107,133,142],"determination":[6,35],"of":[7,17,36,60,81,87,93,96],"norethindrone.These":[8],"either":[11],"complicated":[12],"or":[13],"need":[14],"validation.The":[15],"objective":[16],"this":[18],"work":[19],"was":[20,55,71,75,84,102,117,135,170],"to":[21,106,119,154],"develop":[22],"and":[23,66,78,90,99,114,138,140,173],"validate":[24],"a":[25,124,159,167,183],"simple":[26,168],"reversed":[27],"phase-high":[28],"performance":[29],"liquid":[30,126],"chromatographic":[31],"method":[32,116,134,169],"norethindrone":[37,121],"in":[38,149,176,178],"dissolution":[39],"media.A":[40],"Thermo":[41],"Scientific":[42],"C18":[43],"column":[44],"(250":[45],"mm":[46,49],"\u00d7":[47],"4.6":[48],"ID,":[50],"5":[51,67],"\u00b5m":[52],"pore":[53],"size)":[54],"used.A":[56],"mobile":[57],"phase":[58],"consisting":[59],"deionized":[61],"water:":[62],"acetonitrile":[63],"(50:50,":[64],"v/v)":[65],"ml/l":[68],"acetic":[69],"acid":[70],"used.The":[72],"flow":[73],"rate":[74],"1.3":[76],"ml/minute":[77],"wavelength":[80],"detection":[83],"245":[85],"nm.Validation":[86],"linearity,":[88],"accuracy":[89],"precision,":[91],"limit":[92,95],"detection,":[94],"quantification,":[97],"specificity,":[98],"stability":[100,148],"(degradation)":[101],"carried":[103],"out":[104],"according":[105],"International":[108],"Conference":[109],"on":[110],"Harmonization":[111],"guidelines.The":[112],"developed":[113],"validated":[115],"used":[118,174],"study":[120],"release":[122,157,181,186],"from":[123,158,182],"nanoparticulate":[125,187],"medicated":[127],"formulation":[128],"(LMF).The":[129],"results":[130],"indicated":[131],"that":[132],"simple,":[136],"accurate":[137],"precise,":[139],"met":[141],"acceptance":[143],"criteria.The":[144],"drug":[145,180],"exhibited":[146],"higher":[147],"basic":[150],"media":[151],"when":[152],"compared":[153],"acidic":[155],"media.Drug":[156],"LMF":[160],"(nanoemulsion)":[161],"followed":[162],"zero":[163],"order":[164],"kinetics.In":[165],"conclusion,":[166],"developed,":[171],"validated,":[172],"successfully":[175],"evaluating":[177],"vitro":[179],"sustained":[184],"release/controlled":[185],"LMF.":[188]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2022-05-11T00:00:00"}