{"id":"https://openalex.org/W4229374147","doi":"https://doi.org/10.1183/23120541.lsc-2022.4","title":"The bacteriology of pleural infection using next generation sequencing: The Oxford Pleural Infection Metagenomics Studies (TORPIDS)","display_name":"The bacteriology of pleural infection using next generation sequencing: The Oxford Pleural Infection Metagenomics Studies (TORPIDS)","publication_year":2022,"publication_date":"2022-03-10","ids":{"openalex":"https://openalex.org/W4229374147","doi":"https://doi.org/10.1183/23120541.lsc-2022.4"},"language":"en","primary_location":{"id":"doi:10.1183/23120541.lsc-2022.4","doi":"https://doi.org/10.1183/23120541.lsc-2022.4","is_oa":false,"landing_page_url":"https://doi.org/10.1183/23120541.lsc-2022.4","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Respiratory infections and bronchiectasis","raw_type":"proceedings-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008108221","display_name":"Nikolaos I. Kanellakis","orcid":"https://orcid.org/0000-0002-0065-2282","observed_orcids":["https://orcid.org/0000-0002-0065-2282"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nikolaos I. Kanellakis","raw_affiliation_strings":["Laboratory of Pleural and Lung Cancer Translational Research, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Pleural and Lung Cancer Translational Research, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030408391","display_name":"John Wrightson","orcid":"https://orcid.org/0000-0002-3036-9672","observed_orcids":["https://orcid.org/0000-0002-3036-9672"]},"institutions":[{"id":"https://openalex.org/I2801179840","display_name":"Churchill Hospital","ror":"https://ror.org/009vheq40","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801179840","https://openalex.org/I4210147381"]},{"id":"https://openalex.org/I4210147381","display_name":"Oxford University Hospitals NHS Trust","ror":"https://ror.org/03h2bh287","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210147381"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"John Wrightson","raw_affiliation_strings":["Oxford Centre for Respiratory Medicine, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, Oxford, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oxford Centre for Respiratory Medicine, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, Oxford, United Kingdom","institution_ids":["https://openalex.org/I2801179840","https://openalex.org/I4210147381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053362604","display_name":"Stephen Gerry","orcid":"https://orcid.org/0000-0003-4654-7311","observed_orcids":["https://orcid.org/0000-0003-4654-7311"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Stephen Gerry","raw_affiliation_strings":["Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051440437","display_name":"Nicholas Edward Ilott","orcid":"https://orcid.org/0000-0002-8432-8622","observed_orcids":["https://orcid.org/0000-0002-8432-8622"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I4405264228","display_name":"Kennedy Institute of Rheumatology","ror":"https://ror.org/01ahsqc77","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149","https://openalex.org/I4405264228"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nicholas Ilott","raw_affiliation_strings":["Oxford Centre for Microbiome Studies, Kennedy Institute of Rheumatology, University of Oxford, Oxford, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oxford Centre for Microbiome Studies, Kennedy Institute of Rheumatology, University of Oxford, Oxford, United Kingdom","institution_ids":["https://openalex.org/I40120149","https://openalex.org/I4405264228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110298102","display_name":"John P. Corcoran","orcid":"https://orcid.org/0000-0002-0480-7819","observed_orcids":["https://orcid.org/0000-0002-0480-7819"]},"institutions":[{"id":"https://openalex.org/I2801179840","display_name":"Churchill Hospital","ror":"https://ror.org/009vheq40","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801179840","https://openalex.org/I4210147381"]},{"id":"https://openalex.org/I4210147381","display_name":"Oxford University Hospitals NHS Trust","ror":"https://ror.org/03h2bh287","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210147381"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"John Corcoran","raw_affiliation_strings":["Oxford Centre for Respiratory Medicine, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, Oxford, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oxford Centre for Respiratory Medicine, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, Oxford, United Kingdom","institution_ids":["https://openalex.org/I2801179840","https://openalex.org/I4210147381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060769620","display_name":"Eihab O. Bedawi","orcid":"https://orcid.org/0000-0001-9196-3934","observed_orcids":["https://orcid.org/0000-0001-9196-3934"]},"institutions":[{"id":"https://openalex.org/I2801179840","display_name":"Churchill Hospital","ror":"https://ror.org/009vheq40","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801179840","https://openalex.org/I4210147381"]},{"id":"https://openalex.org/I4210147381","display_name":"Oxford University Hospitals NHS Trust","ror":"https://ror.org/03h2bh287","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210147381"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Eihab Bedawi","raw_affiliation_strings":["Oxford Centre for Respiratory Medicine, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, Oxford, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oxford Centre for Respiratory Medicine, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, Oxford, United Kingdom","institution_ids":["https://openalex.org/I2801179840","https://openalex.org/I4210147381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030430174","display_name":"Rachelle Asciak","orcid":"https://orcid.org/0000-0003-1899-1749","observed_orcids":["https://orcid.org/0000-0003-1899-1749"]},"institutions":[{"id":"https://openalex.org/I2801179840","display_name":"Churchill Hospital","ror":"https://ror.org/009vheq40","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801179840","https://openalex.org/I4210147381"]},{"id":"https://openalex.org/I4210147381","display_name":"Oxford University Hospitals NHS Trust","ror":"https://ror.org/03h2bh287","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210147381"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Rachelle Asciak","raw_affiliation_strings":["Oxford Centre for Respiratory Medicine, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, Oxford, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oxford Centre for Respiratory Medicine, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, Oxford, United Kingdom","institution_ids":["https://openalex.org/I2801179840","https://openalex.org/I4210147381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077244104","display_name":"Andrey Nezhentsev","orcid":"https://orcid.org/0000-0003-4224-8349","observed_orcids":["https://orcid.org/0000-0003-4224-8349"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Andrey Nezhentsev","raw_affiliation_strings":["Laboratory of Pleural and Lung Cancer Translational Research, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Pleural and Lung Cancer Translational Research, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058122305","display_name":"Anand Sundaralingam","orcid":"https://orcid.org/0000-0001-7957-0732","observed_orcids":["https://orcid.org/0000-0001-7957-0732"]},"institutions":[{"id":"https://openalex.org/I2801179840","display_name":"Churchill Hospital","ror":"https://ror.org/009vheq40","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801179840","https://openalex.org/I4210147381"]},{"id":"https://openalex.org/I4210147381","display_name":"Oxford University Hospitals NHS Trust","ror":"https://ror.org/03h2bh287","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210147381"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Anand Sundaralingam","raw_affiliation_strings":["Oxford Centre for Respiratory Medicine, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, Oxford, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oxford Centre for Respiratory Medicine, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, Oxford, United Kingdom","institution_ids":["https://openalex.org/I2801179840","https://openalex.org/I4210147381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053583791","display_name":"Rob Hallifax","orcid":"https://orcid.org/0000-0002-9467-668X","observed_orcids":["https://orcid.org/0000-0002-9467-668X"]},"institutions":[{"id":"https://openalex.org/I2801179840","display_name":"Churchill Hospital","ror":"https://ror.org/009vheq40","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801179840","https://openalex.org/I4210147381"]},{"id":"https://openalex.org/I4210147381","display_name":"Oxford University Hospitals NHS Trust","ror":"https://ror.org/03h2bh287","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210147381"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Rob Hallifax","raw_affiliation_strings":["Oxford Centre for Respiratory Medicine, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, Oxford, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oxford Centre for Respiratory Medicine, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, Oxford, United Kingdom","institution_ids":["https://openalex.org/I2801179840","https://openalex.org/I4210147381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046834504","display_name":"Greta M Economides","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Greta Economides","raw_affiliation_strings":["Laboratory of Pleural and Lung Cancer Translational Research, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Pleural and Lung Cancer Translational Research, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Lucy Bland","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Lucy Bland","raw_affiliation_strings":["Laboratory of Pleural and Lung Cancer Translational Research, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Pleural and Lung Cancer Translational Research, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Elizabeth Daly","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Elizabeth Daly","raw_affiliation_strings":["Laboratory of Pleural and Lung Cancer Translational Research, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Pleural and Lung Cancer Translational Research, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101979690","display_name":"Xuan Yao","orcid":"https://orcid.org/0000-0001-9237-0380","observed_orcids":["https://orcid.org/0000-0001-9237-0380"]},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]},{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["CN","GB"],"is_corresponding":false,"raw_author_name":"Xuan Yao","raw_affiliation_strings":["Chinese Academy of Medical Sciences, China Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chinese Academy of Medical Sciences, China Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom","institution_ids":["https://openalex.org/I200296433","https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081633297","display_name":"Nick A. Maskell","orcid":"https://orcid.org/0000-0002-1276-6500","observed_orcids":["https://orcid.org/0000-0002-1276-6500"]},"institutions":[{"id":"https://openalex.org/I2801520950","display_name":"At Bristol","ror":"https://ror.org/039fp5n52","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I2801520950"]},{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nick Maskell","raw_affiliation_strings":["Academic Respiratory Unit, University of Bristol Medical School Translational Health Sciences, Bristol, Bristol, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Academic Respiratory Unit, University of Bristol Medical School Translational Health Sciences, Bristol, Bristol, United Kingdom","institution_ids":["https://openalex.org/I2801520950","https://openalex.org/I36234482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102906879","display_name":"Robert F. Miller","orcid":"https://orcid.org/0000-0003-2067-4291","observed_orcids":["https://orcid.org/0000-0003-2067-4291"]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Robert Miller","raw_affiliation_strings":["Institute for Global Health, University College London, London, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Global Health, University College London, London, London, United Kingdom","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089282433","display_name":"Derrick W. Crook","orcid":"https://orcid.org/0000-0002-0590-2850","observed_orcids":["https://orcid.org/0000-0002-0590-2850"]},"institutions":[{"id":"https://openalex.org/I2802742124","display_name":"John Radcliffe Hospital","ror":"https://ror.org/0080acb59","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802742124","https://openalex.org/I4210127145","https://openalex.org/I4210147381"]},{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Derrick Crook","raw_affiliation_strings":["Nuffield Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nuffield Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom","institution_ids":["https://openalex.org/I2802742124","https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034784907","display_name":"Timothy Hinks","orcid":"https://orcid.org/0000-0003-0699-2373","observed_orcids":["https://orcid.org/0000-0003-0699-2373"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Timothy Hinks","raw_affiliation_strings":["Respiratory Medicine Unit, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Respiratory Medicine Unit, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077404554","display_name":"Tao Dong","orcid":"https://orcid.org/0000-0003-3545-3758","observed_orcids":["https://orcid.org/0000-0003-3545-3758"]},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]},{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["CN","GB"],"is_corresponding":false,"raw_author_name":"Tao Dong","raw_affiliation_strings":["Chinese Academy of Medical Sciences, China Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chinese Academy of Medical Sciences, China Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom","institution_ids":["https://openalex.org/I200296433","https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048009571","display_name":"Ioannis Psallidas","orcid":"https://orcid.org/0000-0001-7284-0111","observed_orcids":["https://orcid.org/0000-0001-7284-0111"]},"institutions":[{"id":"https://openalex.org/I2801179840","display_name":"Churchill Hospital","ror":"https://ror.org/009vheq40","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801179840","https://openalex.org/I4210147381"]},{"id":"https://openalex.org/I4210147381","display_name":"Oxford University Hospitals NHS Trust","ror":"https://ror.org/03h2bh287","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210147381"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ioannis Psallidas","raw_affiliation_strings":["Oxford Centre for Respiratory Medicine, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, Oxford, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oxford Centre for Respiratory Medicine, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, Oxford, United Kingdom","institution_ids":["https://openalex.org/I2801179840","https://openalex.org/I4210147381"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059272486","display_name":"Najib\u00a0Mahboob Rahman","orcid":"https://orcid.org/0000-0003-1195-1680","observed_orcids":["https://orcid.org/0000-0003-1195-1680"]},"institutions":[{"id":"https://openalex.org/I2801179840","display_name":"Churchill Hospital","ror":"https://ror.org/009vheq40","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801179840","https://openalex.org/I4210147381"]},{"id":"https://openalex.org/I4210147381","display_name":"Oxford University Hospitals NHS Trust","ror":"https://ror.org/03h2bh287","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210147381"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Najib Rahman","raw_affiliation_strings":["Oxford Centre for Respiratory Medicine, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, Oxford, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oxford Centre for Respiratory Medicine, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, Oxford, United Kingdom","institution_ids":["https://openalex.org/I2801179840","https://openalex.org/I4210147381"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":9,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"4","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11356","display_name":"Pleural and Pulmonary Diseases","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11356","display_name":"Pleural and Pulmonary Diseases","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10654","display_name":"Pneumonia and Respiratory Infections","score":0.0034000000450760126,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12167","display_name":"Bacterial Identification and Susceptibility Testing","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pleural-infection","display_name":"pleural infection","score":0.9990000128746033},{"id":"https://openalex.org/keywords/coinfection","display_name":"co-infection","score":0.9269999861717224},{"id":"https://openalex.org/keywords/staphylococcus-aureus","display_name":"Staphylococcus aureus","score":0.8679999709129333},{"id":"https://openalex.org/keywords/enterobacteriaceae","display_name":"Enterobacteriaceae","score":0.9670000076293945},{"id":"https://openalex.org/keywords/streptococcus-pneumoniae","display_name":"Streptococcus pneumoniae","score":0.9589999914169312},{"id":"https://openalex.org/keywords/streptococcus-anginosus-group","display_name":"Streptococcus anginosus group","score":0.9649999737739563},{"id":"https://openalex.org/keywords/anaerobic-bacteria","display_name":"anaerobic bacteria","score":0.9449999928474426},{"id":"https://openalex.org/keywords/gram-negative-bacteria","display_name":"Gram-negative bacteria","score":0.7850000262260437},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.5220000147819519},{"id":"https://openalex.org/keywords/survival","display_name":"survival","score":0.6309999823570251},{"id":"https://openalex.org/keywords/antibiotic-therapy","display_name":"antibiotic therapy","score":0.37400001287460327},{"id":"https://openalex.org/keywords/broad-spectrum-antibiotics","display_name":"broad-spectrum antibiotics","score":0.7570000290870667}],"concepts":[{"id":"https://openalex.org/C2779489039","wikidata":"https://www.wikidata.org/wiki/Q188121","display_name":"Staphylococcus aureus","level":3,"score":0.6716619729995728},{"id":"https://openalex.org/C53162352","wikidata":"https://www.wikidata.org/wiki/Q243748","display_name":"Bacteriology","level":3,"score":0.6683105230331421},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5515178442001343},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.537892758846283},{"id":"https://openalex.org/C2781253189","wikidata":"https://www.wikidata.org/wiki/Q221179","display_name":"Streptococcus pneumoniae","level":3,"score":0.5228196382522583},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4897761344909668},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.47407642006874084},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.44215893745422363},{"id":"https://openalex.org/C2910829522","wikidata":"https://www.wikidata.org/wiki/Q309538","display_name":"Streptococcus anginosus","level":4,"score":0.44143807888031006},{"id":"https://openalex.org/C2778276568","wikidata":"https://www.wikidata.org/wiki/Q190161","display_name":"Streptococcus","level":3,"score":0.332174152135849},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.265688419342041},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1183/23120541.lsc-2022.4","doi":"https://doi.org/10.1183/23120541.lsc-2022.4","is_oa":false,"landing_page_url":"https://doi.org/10.1183/23120541.lsc-2022.4","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Respiratory infections and bronchiectasis","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9907000064849854,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4229043485","https://openalex.org/W3094807932","https://openalex.org/W3121957009","https://openalex.org/W2986082262","https://openalex.org/W2134202313","https://openalex.org/W1997621977","https://openalex.org/W2038126394","https://openalex.org/W4388410795","https://openalex.org/W4410275613","https://openalex.org/W2511476392"],"abstract_inverted_index":{"Background:":[0],"Pleural":[1,45,51,81],"infection":[2,18,33,82,108,182,196],"is":[3],"a":[4],"common":[5],"and":[6,12,34,77,96,101,173,201],"severe":[7],"disease":[8],"with":[9,40,89,133,150,158,198],"high":[10],"morbidity":[11],"mortality":[13,195],"worldwide.":[14],"Knowledge":[15],"of":[16,31,37,87,118,124,145,154,161,171],"pleural":[17,32,181],"bacteriology":[19],"remains":[20],"incomplete.":[21],"The":[22,116],"TORPIDS":[23],"study":[24],"was":[25,68,83,131,148,156],"designed":[26],"to":[27,59,70],"discover":[28],"the":[29,50,72,125,137,174,184],"microbiome":[30],"assess":[35],"correlation":[36],"bacterial":[38,75,91],"patterns":[39,76,92],"clinically":[41],"important":[42],"outcomes.":[43,79],"Methods:":[44],"fluid":[46],"samples":[47],"(n=243)":[48],"from":[49],"Infection":[52],"Longitudinal":[53],"Outcome":[54],"Study":[55],"(PILOT)":[56],"were":[57,167],"subjected":[58],"16S":[60],"rRNA":[61],"next":[62],"generation":[63],"sequencing.":[64],"Multivariate":[65],"regression":[66],"analysis":[67],"applied":[69],"investigate":[71],"link":[73],"between":[74],"clinical":[78],"Results:":[80],"predominately":[84],"polymicrobial":[85,97,107],"(79%":[86],"samples)":[88],"diverse":[90],"observed":[93],"in":[94,106,113,180,191],"monomicrobial":[95,114],"disease.":[98],"Mixed":[99],"anaerobes":[100,119],"other":[102],"Gram-negative":[103],"bacteria":[104,123],"predominated":[105],"whereas":[109],"Streptococcus":[110,126],"pneumoniae":[111],"prevailed":[112],"cases.":[115],"presence":[117,138],"(HR=0.46,":[120],"P=0.02)":[121,144],"or":[122,141],"anginosus":[127],"group":[128],"(HR=0.43,":[129],"P=0.04)":[130],"associated":[132,157,197],"better":[134],"survival,":[135],"while":[136],"(HR=5\u00b780,":[139],"P<0\u00b7001)":[140],"dominance":[142],"(HR=3.97,":[143],"Staphylococcus":[146,199],"aureus":[147,200],"linked":[149],"higher":[151,159],"mortality.":[152],"Dominance":[153],"Enterobacteriaceae":[155,202],"risk":[160],"death":[162],"(HR=2.79,":[163],"P=0.04).":[164],"No":[165],"differences":[166],"detected":[168],"for":[169,176,186],"duration":[170],"hospitalisation":[172],"need":[175],"surgery.":[177],"Conclusion:":[178],"Polymicrobiality":[179],"explains":[183],"requirement":[185],"broad":[187],"spectrum":[188,208],"antibiotic":[189,209],"cover":[190],"most":[192],"individuals.":[193],"High":[194],"favours":[203],"more":[204],"aggressive":[205],"but":[206],"narrower":[207],"strategies.":[210]},"counts_by_year":[],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2022-05-10T00:00:00"}