{"id":"https://openalex.org/W4229021533","doi":"https://doi.org/10.1038/s41467-022-30261-3","title":"A multiplex platform for small RNA sequencing elucidates multifaceted tRNA stress response and translational regulation","display_name":"A multiplex platform for small RNA sequencing elucidates multifaceted tRNA stress response and translational regulation","publication_year":2022,"publication_date":"2022-05-05","ids":{"openalex":"https://openalex.org/W4229021533","doi":"https://doi.org/10.1038/s41467-022-30261-3","pmid":"https://pubmed.ncbi.nlm.nih.gov/35513407","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9072684"},"language":"en","primary_location":{"id":"doi:10.1038/s41467-022-30261-3","doi":"https://doi.org/10.1038/s41467-022-30261-3","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-022-30261-3","pdf_url":"https://www.nature.com/articles/s41467-022-30261-3.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41467-022-30261-3.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Christopher P. Watkins","orcid":"https://orcid.org/0000-0002-1707-081X","observed_orcids":["https://orcid.org/0000-0002-1707-081X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Christopher P. Watkins","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, Chicago, IL, 60637, USA"],"raw_orcid":"https://orcid.org/0000-0002-1707-081X","affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Chicago, IL, 60637, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101522156","display_name":"Wen Zhang","orcid":"https://orcid.org/0000-0001-8577-2613","observed_orcids":["https://orcid.org/0000-0001-8577-2613"]},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wen Zhang","raw_affiliation_strings":["Department of Chemistry, University of Chicago, Chicago, IL, 60637, USA"],"raw_orcid":"https://orcid.org/0000-0001-8577-2613","affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Chicago, Chicago, IL, 60637, USA","institution_ids":["https://openalex.org/I40347166"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070969710","display_name":"Adam C. Wylder","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Adam C. Wylder","raw_affiliation_strings":["Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL, 60637, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL, 60637, USA","institution_ids":["https://openalex.org/I40347166"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102926391","display_name":"Christopher D. Katanski","orcid":"https://orcid.org/0000-0002-1707-081X","observed_orcids":["https://orcid.org/0000-0002-1707-081X"]},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Christopher D. Katanski","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, Chicago, IL, 60637, USA. katanski@uchicago.edu","Department of Biochemistry and Molecular Biology, Chicago, IL, 60637, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Chicago, IL, 60637, USA. katanski@uchicago.edu","institution_ids":["https://openalex.org/I40347166"]},{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Chicago, IL, 60637, USA","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003648553","display_name":"Tao Pan","orcid":"https://orcid.org/0000-0003-1096-8405","observed_orcids":["https://orcid.org/0000-0003-1096-8405"]},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Tao Pan","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, Chicago, IL, 60637, USA. taopan@uchicago.edu","Department of Biochemistry and Molecular Biology, Chicago, IL, 60637, USA"],"raw_orcid":"https://orcid.org/0000-0003-1096-8405","affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Chicago, IL, 60637, USA. taopan@uchicago.edu","institution_ids":["https://openalex.org/I40347166"]},{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Chicago, IL, 60637, USA","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5003648553","https://openalex.org/A5102926391"],"corresponding_institution_ids":["https://openalex.org/I40347166"],"apc_list":{"value":5890,"currency":"USD","value_usd":5890},"apc_paid":{"value":5890,"currency":"USD","value_usd":5890},"fwci":4.6445,"has_fulltext":true,"cited_by_count":77,"citation_normalized_percentile":{"value":0.97021956,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"13","issue":"1","first_page":"2491","last_page":"2491"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.7109000086784363,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.7109000086784363,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.2865999937057495,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/small-rna-sequencing","display_name":"small RNA sequencing","score":0.6909999847412109},{"id":"https://openalex.org/keywords/trna","display_name":"tRNA","score":0.8560000061988831},{"id":"https://openalex.org/keywords/trna-derived-fragments","display_name":"tRNA-derived fragments","score":0.6460000276565552},{"id":"https://openalex.org/keywords/trna-modification","display_name":"tRNA modification","score":0.781000018119812},{"id":"https://openalex.org/keywords/heat-shock","display_name":"heat shock","score":0.6209999918937683},{"id":"https://openalex.org/keywords/hydrogen-peroxide","display_name":"hydrogen peroxide","score":0.9070000052452087},{"id":"https://openalex.org/keywords/arsenite","display_name":"arsenite","score":0.7960000038146973},{"id":"https://openalex.org/keywords/cellular-stress-response","display_name":"cellular stress response","score":0.7390000224113464},{"id":"https://openalex.org/keywords/translational-control","display_name":"translational regulation","score":0.8700000047683716},{"id":"https://openalex.org/keywords/translation-elongation","display_name":"translation elongation","score":0.9210000038146973},{"id":"https://openalex.org/keywords/trna-biogenesis","display_name":"tRNA biosynthesis","score":0.703000009059906}],"concepts":[{"id":"https://openalex.org/C153957851","wikidata":"https://www.wikidata.org/wiki/Q201448","display_name":"Transfer RNA","level":4,"score":0.7650622129440308},{"id":"https://openalex.org/C2781188995","wikidata":"https://www.wikidata.org/wiki/Q6934982","display_name":"Multiplex","level":2,"score":0.6844180822372437},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.5761831402778625},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5747952461242676},{"id":"https://openalex.org/C39685955","wikidata":"https://www.wikidata.org/wiki/Q3455905","display_name":"Translational regulation","level":5,"score":0.5381816625595093},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.513748049736023},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4851611256599426},{"id":"https://openalex.org/C78604142","wikidata":"https://www.wikidata.org/wiki/Q1640582","display_name":"Fight-or-flight response","level":3,"score":0.44248074293136597},{"id":"https://openalex.org/C149364088","wikidata":"https://www.wikidata.org/wiki/Q185917","display_name":"Translation (biology)","level":4,"score":0.41276291012763977},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.28150495886802673},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.24063166975975037}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012323","descriptor_name":"RNA Processing, Post-Transcriptional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012343","descriptor_name":"RNA, Transfer","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012343","descriptor_name":"RNA, Transfer","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1038/s41467-022-30261-3","doi":"https://doi.org/10.1038/s41467-022-30261-3","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-022-30261-3","pdf_url":"https://www.nature.com/articles/s41467-022-30261-3.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9072684","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9072684","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nat Commun","raw_type":"Text"},{"id":"pmid:35513407","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35513407","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature communications","raw_type":"Journal Article"},{"id":"pmh:oai:RePEc:nat:natcom:v:13:y:2022:i:1:d:10.1038_s41467-022-30261-3","doi":null,"is_oa":false,"landing_page_url":"https://www.nature.com/articles/s41467-022-30261-3","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:71d4401718c8473fb3cbaecdca743cef","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/71d4401718c8473fb3cbaecdca743cef","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1038/s41467-022-30261-3","doi":"https://doi.org/10.1038/s41467-022-30261-3","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-022-30261-3","pdf_url":"https://www.nature.com/articles/s41467-022-30261-3.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G3042014112","display_name":null,"funder_award_id":"RM1 HG008935","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G6557951883","display_name":"Recognition and mechanism of N6-methyl adenosine modifications","funder_award_id":"R01GM113194","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G8066556814","display_name":null,"funder_award_id":"R01GM113194","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G9000911514","display_name":"Center for dynamic RNA epitranscriptomes - Renewal","funder_award_id":"RM1HG008935","funder_id":"https://openalex.org/F4320337348","funder_display_name":"National Human Genome Research Institute"}],"funders":[{"id":"https://openalex.org/F4320306085","display_name":"U.S. Department of Health and Human Services","ror":"https://ror.org/033jnv181"},{"id":"https://openalex.org/F4320306159","display_name":"W. M. Keck Foundation","ror":"https://ror.org/000dswa46"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337348","display_name":"National Human Genome Research Institute","ror":"https://ror.org/00baak391"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4229021533.pdf","grobid_xml":"https://content.openalex.org/works/W4229021533.grobid-xml"},"referenced_works_count":59,"referenced_works":["https://openalex.org/W1429519121","https://openalex.org/W1548166250","https://openalex.org/W1982749428","https://openalex.org/W1991524704","https://openalex.org/W1991807334","https://openalex.org/W2044954993","https://openalex.org/W2051037155","https://openalex.org/W2076772609","https://openalex.org/W2078556683","https://openalex.org/W2104261397","https://openalex.org/W2108138064","https://openalex.org/W2108234281","https://openalex.org/W2109140791","https://openalex.org/W2112765717","https://openalex.org/W2114147818","https://openalex.org/W2115495500","https://openalex.org/W2124825601","https://openalex.org/W2131271579","https://openalex.org/W2142584500","https://openalex.org/W2167133210","https://openalex.org/W2205433875","https://openalex.org/W2223836536","https://openalex.org/W2271995006","https://openalex.org/W2341539131","https://openalex.org/W2434565902","https://openalex.org/W2473711714","https://openalex.org/W2516238376","https://openalex.org/W2529694725","https://openalex.org/W2588097017","https://openalex.org/W2590034108","https://openalex.org/W2601455724","https://openalex.org/W2613783582","https://openalex.org/W2624373429","https://openalex.org/W2728379842","https://openalex.org/W2742715352","https://openalex.org/W2751076435","https://openalex.org/W2797564997","https://openalex.org/W2811478179","https://openalex.org/W2879135867","https://openalex.org/W2891388080","https://openalex.org/W2895818115","https://openalex.org/W2900044275","https://openalex.org/W2904390297","https://openalex.org/W2911351489","https://openalex.org/W2912327568","https://openalex.org/W2942949465","https://openalex.org/W2948021559","https://openalex.org/W2953460056","https://openalex.org/W2955930197","https://openalex.org/W2993183257","https://openalex.org/W3013352992","https://openalex.org/W3026387521","https://openalex.org/W3033342031","https://openalex.org/W3043335865","https://openalex.org/W3048999744","https://openalex.org/W3113197893","https://openalex.org/W3130039809","https://openalex.org/W3133557863","https://openalex.org/W3153491424"],"related_works":["https://openalex.org/W2167133210","https://openalex.org/W6920674700","https://openalex.org/W3173468273","https://openalex.org/W7133521895","https://openalex.org/W7160511538","https://openalex.org/W3009535296","https://openalex.org/W3160139315","https://openalex.org/W2589343606","https://openalex.org/W1198543632","https://openalex.org/W4223981558"],"abstract_inverted_index":{"Abstract":[0],"Small":[1,43],"RNAs":[2,149],"include":[3],"tRNA,":[4],"snRNA,":[5],"micro-RNA,":[6],"tRNA":[7,90,95,101,104,125,137],"fragments":[8],"and":[9,23,65,73,83,97,105,150],"others":[10],"that":[11,92,123],"constitute":[12],">":[13],"90%":[14],"of":[15,79,114,136,144,147],"RNA":[16,38,64,82],"copy":[17],"numbers":[18],"in":[19,117,153],"a":[20,52,88,112],"human":[21],"cell":[22],"perform":[24],"many":[25],"essential":[26],"functions.":[27],"Popular":[28],"small":[29,37,54,63,148],"RNA-seq":[30,44,55],"strategies":[31],"limit":[32],"the":[33,134,142],"insights":[34],"into":[35],"coordinated":[36,89],"response":[39,67,91,107,154],"to":[40,60,68,108,155],"cellular":[41,62,81],"stress.":[42,75],"also":[45,121],"lacks":[46],"multiplexing":[47],"capabilities.":[48],"Here,":[49],"we":[50,86,110],"report":[51],"multiplex":[53],"library":[56],"preparation":[57],"method":[58],"(MSR-seq)":[59],"investigate":[61],"mRNA":[66,106],"heat":[69],"shock,":[70],"hydrogen":[71],"peroxide,":[72],"arsenite":[74],"Comparing":[76],"stress-induced":[77,115],"changes":[78],"total":[80],"polysome-associated":[84],"RNA,":[85],"identify":[87],"involves":[93],"polysome-specific":[94],"abundance":[96],"synergistic":[98],"N3-methylcytosine":[99],"(m3C)":[100],"modification.":[102],"Combining":[103],"stress":[109],"reveal":[111],"mechanism":[113],"down-regulation":[116],"translational":[118],"elongation.":[119],"We":[120],"find":[122],"native":[124],"molecules":[126],"lacking":[127],"several":[128],"modifications":[129,152],"are":[130],"biased":[131],"reservoirs":[132],"for":[133],"biogenesis":[135],"fragments.":[138],"Our":[139],"results":[140],"demonstrate":[141],"importance":[143],"simultaneous":[145],"investigation":[146],"their":[151],"varying":[156],"biological":[157],"conditions.":[158]},"counts_by_year":[{"year":2026,"cited_by_count":20},{"year":2025,"cited_by_count":18},{"year":2024,"cited_by_count":21},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":8}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2022-05-08T00:00:00"}