{"id":"https://openalex.org/W4226059797","doi":"https://doi.org/10.1039/d1an02321g","title":"Single-cell droplet microfluidics for biomedical applications","display_name":"Single-cell droplet microfluidics for biomedical applications","publication_year":2022,"publication_date":"2022-01-01","ids":{"openalex":"https://openalex.org/W4226059797","doi":"https://doi.org/10.1039/d1an02321g","pmid":"https://pubmed.ncbi.nlm.nih.gov/35506869"},"language":"en","primary_location":{"id":"doi:10.1039/d1an02321g","doi":"https://doi.org/10.1039/d1an02321g","is_oa":true,"landing_page_url":"https://doi.org/10.1039/d1an02321g","pdf_url":"https://pubs.rsc.org/en/content/articlepdf/2022/an/d1an02321g","source":{"id":"https://openalex.org/S105746325","display_name":"The Analyst","issn_l":"0003-2654","issn":["0003-2654","1364-5528"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Analyst","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://pubs.rsc.org/en/content/articlepdf/2022/an/d1an02321g","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Dan Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dan Liu","raw_affiliation_strings":["Departments of Biomedical Engineering and Pathology, School of Basic Medical Science, Central South University, Changsha, Hunan 410013, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Biomedical Engineering and Pathology, School of Basic Medical Science, Central South University, Changsha, Hunan 410013, China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065216709","display_name":"Meilin Sun","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Meilin Sun","raw_affiliation_strings":["Departments of Biomedical Engineering and Pathology, School of Basic Medical Science, Central South University, Changsha, Hunan 410013, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Biomedical Engineering and Pathology, School of Basic Medical Science, Central South University, Changsha, Hunan 410013, China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100392712","display_name":"Jinwei Zhang","orcid":"https://orcid.org/0000-0002-9116-358X","observed_orcids":["https://orcid.org/0000-0002-9116-358X","https://orcid.org/0009-0007-2262-5879"]},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jinwei Zhang","raw_affiliation_strings":["Departments of Biomedical Engineering and Pathology, School of Basic Medical Science, Central South University, Changsha, Hunan 410013, China"],"raw_orcid":"https://orcid.org/0000-0002-9116-358X","affiliations":[{"raw_affiliation_string":"Departments of Biomedical Engineering and Pathology, School of Basic Medical Science, Central South University, Changsha, Hunan 410013, China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083665930","display_name":"Rui Hua Hu","orcid":"https://orcid.org/0000-0001-7799-5198","observed_orcids":["https://orcid.org/0000-0001-7799-5198"]},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Rui Hu","raw_affiliation_strings":["Departments of Biomedical Engineering and Pathology, School of Basic Medical Science, Central South University, Changsha, Hunan 410013, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Biomedical Engineering and Pathology, School of Basic Medical Science, Central South University, Changsha, Hunan 410013, China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054186747","display_name":"Wenzhu Fu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenzhu Fu","raw_affiliation_strings":["Departments of Biomedical Engineering and Pathology, School of Basic Medical Science, Central South University, Changsha, Hunan 410013, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Biomedical Engineering and Pathology, School of Basic Medical Science, Central South University, Changsha, Hunan 410013, China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082168536","display_name":"Tingting Xuanyuan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tingting Xuanyuan","raw_affiliation_strings":["Departments of Biomedical Engineering and Pathology, School of Basic Medical Science, Central South University, Changsha, Hunan 410013, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Biomedical Engineering and Pathology, School of Basic Medical Science, Central South University, Changsha, Hunan 410013, China","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083183481","display_name":"Wenming Liu","orcid":"https://orcid.org/0000-0002-7044-1130","observed_orcids":["https://orcid.org/0000-0002-7044-1130","https://orcid.org/0009-0004-1870-904X"]},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Wenming Liu","raw_affiliation_strings":["Departments of Biomedical Engineering and Pathology, School of Basic Medical Science, Central South University, Changsha, Hunan 410013, China"],"raw_orcid":"https://orcid.org/0000-0002-7044-1130","affiliations":[{"raw_affiliation_string":"Departments of Biomedical Engineering and Pathology, School of Basic Medical Science, Central South University, Changsha, Hunan 410013, China","institution_ids":["https://openalex.org/I139660479"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5083183481"],"corresponding_institution_ids":["https://openalex.org/I139660479"],"apc_list":null,"apc_paid":null,"fwci":1.8031,"has_fulltext":true,"cited_by_count":105,"citation_normalized_percentile":{"value":0.86058302,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"147","issue":"11","first_page":"2294","last_page":"2316"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11407","display_name":"Innovative Microfluidic and Catalytic Techniques Innovation","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11407","display_name":"Innovative Microfluidic and Catalytic Techniques Innovation","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10412","display_name":"Microfluidic and Capillary Electrophoresis Applications","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12452","display_name":"Electrowetting and Microfluidic Technologies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/droplet-microfluidics","display_name":"droplet microfluidics","score":0.824999988079071},{"id":"https://openalex.org/keywords/single-cell-analysis","display_name":"single-cell analysis","score":0.7480000257492065},{"id":"https://openalex.org/keywords/cell-heterogeneity","display_name":"cellular heterogeneity","score":0.8730000257492065},{"id":"https://openalex.org/keywords/droplet-formation","display_name":"droplet formation","score":0.8240000009536743},{"id":"https://openalex.org/keywords/hydrogel-microspheres","display_name":"hydrogel microspheres","score":0.9160000085830688},{"id":"https://openalex.org/keywords/small-molecule-detection","display_name":"small molecule detection","score":0.8629999756813049},{"id":"https://openalex.org/keywords/protein-analysis","display_name":"protein analysis","score":0.9700000286102295},{"id":"https://openalex.org/keywords/drug-screening","display_name":"drug screening","score":0.9810000061988831},{"id":"https://openalex.org/keywords/regenerative-therapy","display_name":"regenerative therapy","score":0.7490000128746033},{"id":"https://openalex.org/keywords/early-diagnosis","display_name":"early diagnosis","score":0.9700000286102295}],"concepts":[{"id":"https://openalex.org/C8673954","wikidata":"https://www.wikidata.org/wiki/Q138845","display_name":"Microfluidics","level":2,"score":0.953020453453064},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.6792576313018799},{"id":"https://openalex.org/C66782513","wikidata":"https://www.wikidata.org/wiki/Q864601","display_name":"Biomedicine","level":2,"score":0.6586475968360901},{"id":"https://openalex.org/C2776950831","wikidata":"https://www.wikidata.org/wiki/Q15635432","display_name":"Single-cell analysis","level":3,"score":0.5588266849517822},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.45035797357559204},{"id":"https://openalex.org/C183696295","wikidata":"https://www.wikidata.org/wiki/Q2487696","display_name":"Biochemical engineering","level":1,"score":0.357207715511322},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.2504798173904419},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.24815410375595093},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.20651358366012573},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.1597270965576172},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.1554676592350006},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.11305880546569824},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D020100","descriptor_name":"Hydrogels","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020100","descriptor_name":"Hydrogels","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020100","descriptor_name":"Hydrogels","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044085","descriptor_name":"Microfluidics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D044085","descriptor_name":"Microfluidics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D044085","descriptor_name":"Microfluidics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D046210","descriptor_name":"Microfluidic Analytical Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D046210","descriptor_name":"Microfluidic Analytical Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D046210","descriptor_name":"Microfluidic Analytical Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1039/d1an02321g","doi":"https://doi.org/10.1039/d1an02321g","is_oa":true,"landing_page_url":"https://doi.org/10.1039/d1an02321g","pdf_url":"https://pubs.rsc.org/en/content/articlepdf/2022/an/d1an02321g","source":{"id":"https://openalex.org/S105746325","display_name":"The Analyst","issn_l":"0003-2654","issn":["0003-2654","1364-5528"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Analyst","raw_type":"journal-article"},{"id":"pmid:35506869","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35506869","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Analyst","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1039/d1an02321g","doi":"https://doi.org/10.1039/d1an02321g","is_oa":true,"landing_page_url":"https://doi.org/10.1039/d1an02321g","pdf_url":"https://pubs.rsc.org/en/content/articlepdf/2022/an/d1an02321g","source":{"id":"https://openalex.org/S105746325","display_name":"The Analyst","issn_l":"0003-2654","issn":["0003-2654","1364-5528"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Analyst","raw_type":"journal-article"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/9","display_name":"Industry, innovation and infrastructure","score":0.4699999988079071}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1400854782","display_name":null,"funder_award_id":"202045001","funder_id":"https://openalex.org/F4320321514","funder_display_name":"Central South University"},{"id":"https://openalex.org/G1525255805","display_name":null,"funder_award_id":"21B0008","funder_id":"https://openalex.org/F4320311213","funder_display_name":"Education Department of Hunan Province"},{"id":"https://openalex.org/G3662236226","display_name":null,"funder_award_id":"31971328","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3985400432","display_name":"\u6c14\u52a8\u5f0f\u80bf\u7624\u7403\u81ea\u7ec4\u88c5\u5fae\u6d41\u63a7\u82af\u7247\u7684\u7814\u5236\u53ca\u5176\u9ad8\u901a\u91cf\u5206\u6790\u5e94\u7528","funder_award_id":"31100726","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4315566577","display_name":null,"funder_award_id":"2021zzts0930","funder_id":"https://openalex.org/F4320335880","funder_display_name":"Fundamental Research Funds for Central Universities of the Central South University"},{"id":"https://openalex.org/G5163028240","display_name":null,"funder_award_id":"202045001","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G569385000","display_name":"\u96c6\u6210\u5fae\u6d41\u63a7\u5927\u89c4\u6a21\u795e\u7ecf\u7f51\u7edc\u5f0f\u8111\u7f3a\u8840\u6a21\u578b\u6784\u5efa\u53ca\u8f74\u7a81\u53d8\u6027\u5206\u5b50\u673a\u5236\u7814\u7a76\u5e94\u7528","funder_award_id":"31470971","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6984616395","display_name":null,"funder_award_id":"32171450","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7336939631","display_name":null,"funder_award_id":"202045001","funder_id":"https://openalex.org/F4320335880","funder_display_name":"Fundamental Research Funds for Central Universities of the Central South University"},{"id":"https://openalex.org/G8208766576","display_name":null,"funder_award_id":"202045001","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"}],"funders":[{"id":"https://openalex.org/F4320311213","display_name":"Education Department of Hunan Province","ror":"https://ror.org/05ckg3w11"},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321514","display_name":"Central South University","ror":"https://ror.org/00f1zfq44"},{"id":"https://openalex.org/F4320335787","display_name":"Fundamental Research Funds for the Central Universities","ror":null},{"id":"https://openalex.org/F4320335880","display_name":"Fundamental Research Funds for Central Universities of the Central South University","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4226059797.pdf","grobid_xml":"https://content.openalex.org/works/W4226059797.grobid-xml"},"referenced_works_count":150,"referenced_works":["https://openalex.org/W1212466219","https://openalex.org/W1525649312","https://openalex.org/W1852276487","https://openalex.org/W1871056301","https://openalex.org/W1901255537","https://openalex.org/W1926708839","https://openalex.org/W1959447435","https://openalex.org/W1968280004","https://openalex.org/W1973244829","https://openalex.org/W1974934611","https://openalex.org/W1980221373","https://openalex.org/W1981233250","https://openalex.org/W1981427358","https://openalex.org/W1995065737","https://openalex.org/W2000018936","https://openalex.org/W2006632330","https://openalex.org/W2009434334","https://openalex.org/W2010130647","https://openalex.org/W2010241268","https://openalex.org/W2015029046","https://openalex.org/W2022368399","https://openalex.org/W2032805499","https://openalex.org/W2032930176","https://openalex.org/W2033906622","https://openalex.org/W2048657818","https://openalex.org/W2059018615","https://openalex.org/W2064803625","https://openalex.org/W2065391011","https://openalex.org/W2074758993","https://openalex.org/W2075026686","https://openalex.org/W2088212087","https://openalex.org/W2091124606","https://openalex.org/W2094016262","https://openalex.org/W2111789241","https://openalex.org/W2111940407","https://openalex.org/W2119475668","https://openalex.org/W2122309838","https://openalex.org/W2122917672","https://openalex.org/W2123398097","https://openalex.org/W2126832798","https://openalex.org/W2139066527","https://openalex.org/W2148892249","https://openalex.org/W2152152614","https://openalex.org/W2154602368","https://openalex.org/W2160742626","https://openalex.org/W2170669450","https://openalex.org/W2172529835","https://openalex.org/W2248179576","https://openalex.org/W2265738804","https://openalex.org/W2267969766","https://openalex.org/W2274643653","https://openalex.org/W2284043155","https://openalex.org/W2291829493","https://openalex.org/W2297436952","https://openalex.org/W2320611528","https://openalex.org/W2333850009","https://openalex.org/W2415256212","https://openalex.org/W2472280754","https://openalex.org/W2515253655","https://openalex.org/W2515346563","https://openalex.org/W2536336801","https://openalex.org/W2539835785","https://openalex.org/W2548144690","https://openalex.org/W2561620933","https://openalex.org/W2583657844","https://openalex.org/W2588524741","https://openalex.org/W2597510857","https://openalex.org/W2609171100","https://openalex.org/W2617378503","https://openalex.org/W2618124169","https://openalex.org/W2620147451","https://openalex.org/W2734680486","https://openalex.org/W2746617867","https://openalex.org/W2750595332","https://openalex.org/W2766841662","https://openalex.org/W2780192672","https://openalex.org/W2782290650","https://openalex.org/W2784016091","https://openalex.org/W2786402081","https://openalex.org/W2789133255","https://openalex.org/W2791731597","https://openalex.org/W2794000971","https://openalex.org/W2794256317","https://openalex.org/W2800727099","https://openalex.org/W2805330522","https://openalex.org/W2807526193","https://openalex.org/W2885238451","https://openalex.org/W2885999695","https://openalex.org/W2886125669","https://openalex.org/W2886776561","https://openalex.org/W2889117795","https://openalex.org/W2889374739","https://openalex.org/W2889501032","https://openalex.org/W2891286176","https://openalex.org/W2892131216","https://openalex.org/W2894279258","https://openalex.org/W2896251161","https://openalex.org/W2897902167","https://openalex.org/W2898047543","https://openalex.org/W2898328144","https://openalex.org/W2899671321","https://openalex.org/W2904939852","https://openalex.org/W2910131444","https://openalex.org/W2922426886","https://openalex.org/W2924513712","https://openalex.org/W2937039249","https://openalex.org/W2937722617","https://openalex.org/W2945517005","https://openalex.org/W2947608130","https://openalex.org/W2947895167","https://openalex.org/W2953060032","https://openalex.org/W2953773726","https://openalex.org/W2959439516","https://openalex.org/W2971290491","https://openalex.org/W2972522081","https://openalex.org/W2975879361","https://openalex.org/W2977380564","https://openalex.org/W2978465375","https://openalex.org/W2982088214","https://openalex.org/W2990191632","https://openalex.org/W2990598561","https://openalex.org/W2990955067","https://openalex.org/W2991097214","https://openalex.org/W2991265763","https://openalex.org/W3004403595","https://openalex.org/W3007919088","https://openalex.org/W3012756313","https://openalex.org/W3013072344","https://openalex.org/W3015165983","https://openalex.org/W3016733706","https://openalex.org/W3020198695","https://openalex.org/W3023224713","https://openalex.org/W3027162480","https://openalex.org/W3027269763","https://openalex.org/W3036721210","https://openalex.org/W3036883920","https://openalex.org/W3044529523","https://openalex.org/W3082110537","https://openalex.org/W3089561558","https://openalex.org/W3091355883","https://openalex.org/W3091970064","https://openalex.org/W3103530305","https://openalex.org/W3116170199","https://openalex.org/W3121484653","https://openalex.org/W3126429056","https://openalex.org/W3151594251","https://openalex.org/W3175882162","https://openalex.org/W3211802114","https://openalex.org/W4251699164","https://openalex.org/W4253260323"],"related_works":["https://openalex.org/W4407838044","https://openalex.org/W4366428875","https://openalex.org/W4315865051","https://openalex.org/W2970361009","https://openalex.org/W4409186524","https://openalex.org/W4417164066","https://openalex.org/W2970010977","https://openalex.org/W2136807970","https://openalex.org/W3117428659","https://openalex.org/W2990191632"],"abstract_inverted_index":{"Single-cell":[0],"manipulation":[1,45],"and":[2,14,18,35,46,55,98,114,122,132,141,147,167,170],"analysis":[3,47,172],"is":[4,48,83],"critical":[5],"to":[6,67,110,186],"the":[7,20,51,57,76,92,99,108,127,180],"study":[8],"of":[9,40,50,59,75,79,88,102,129,156,173],"many":[10],"fundamental":[11],"biological":[12],"processes":[13],"uncovering":[15],"cellular":[16],"heterogeneity,":[17],"presents":[19],"potential":[21],"for":[22,126],"extremely":[23],"valuable":[24],"applications":[25,155,189],"in":[26,43,112,160,190],"biomedical":[27],"fields,":[28],"including":[29],"neuroscience,":[30],"regenerative":[31],"therapy,":[32],"early":[33],"diagnosis,":[34],"drug":[36,168],"screening.":[37],"The":[38,85,152],"use":[39],"microfluidic":[41,89,103,124],"technologies":[42],"single-cell":[44,80,130,145,157,191],"one":[49],"most":[52],"promising":[53],"approaches":[54],"enables":[56],"creation":[58],"innovative":[60],"conditions":[61],"that":[62,182],"are":[63,105,135,150,176,194],"impractical":[64],"or":[65],"impossible":[66],"achieve":[68],"using":[69],"conventional":[70],"methods.":[71],"Herein,":[72],"an":[73],"overview":[74],"technological":[77],"development":[78],"droplet":[81,90,96,116,146,158,192],"microfluidics":[82,121,159,193],"presented.":[84],"significant":[86],"advantages":[87],"technology,":[91],"dynamic":[93],"parameters":[94],"affecting":[95],"production,":[97],"geometric":[100],"structures":[101],"devices":[104],"emphasized.":[106],"Furthermore,":[107],"progress":[109],"date":[111],"passive":[113],"active":[115],"generation":[117],"methods":[118],"based":[119],"on":[120],"various":[123],"tools":[125],"production":[128],"droplets":[131],"hydrogel":[133,148],"microspheres":[134],"summarized.":[136],"Their":[137],"key":[138],"features,":[139],"achievements,":[140],"limitations":[142],"associated":[143],"with":[144],"formation":[149],"discussed.":[151],"recent":[153],"popularized":[154],"biomedicine":[161],"involving":[162],"small-molecule":[163],"detection,":[164],"protein":[165],"analysis,":[166],"screening":[169],"genetic":[171],"single":[174],"cells":[175],"explored":[177],"too.":[178],"Finally,":[179],"challenges":[181],"must":[183],"be":[184],"overcome":[185],"enable":[187],"future":[188],"highlighted.":[195]},"counts_by_year":[{"year":2026,"cited_by_count":23},{"year":2025,"cited_by_count":25},{"year":2024,"cited_by_count":28},{"year":2023,"cited_by_count":21},{"year":2022,"cited_by_count":7}],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2022-05-05T00:00:00"}
