{"id":"https://openalex.org/W4226040427","doi":"https://doi.org/10.1128/mbio.02463-21","title":"The Histone H1-Like Protein AlgP Facilitates Even Spacing of Polyphosphate Granules in Pseudomonas aeruginosa","display_name":"The Histone H1-Like Protein AlgP Facilitates Even Spacing of Polyphosphate Granules in Pseudomonas aeruginosa","publication_year":2022,"publication_date":"2022-04-18","ids":{"openalex":"https://openalex.org/W4226040427","doi":"https://doi.org/10.1128/mbio.02463-21","pmid":"https://pubmed.ncbi.nlm.nih.gov/35435704","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9239181"},"language":"en","primary_location":{"id":"doi:10.1128/mbio.02463-21","doi":"https://doi.org/10.1128/mbio.02463-21","is_oa":true,"landing_page_url":"https://doi.org/10.1128/mbio.02463-21","pdf_url":null,"source":{"id":"https://openalex.org/S4210201176","display_name":"mBio","issn_l":"2150-7511","issn":["2150-7511","2161-2129"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"mBio","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1128/mbio.02463-21","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049306589","display_name":"Ravi Chawla","orcid":"https://orcid.org/0000-0003-1867-9528","observed_orcids":["https://orcid.org/0000-0003-1867-9528"]},"institutions":[{"id":"https://openalex.org/I123431417","display_name":"Scripps Research Institute","ror":"https://ror.org/02dxx6824","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I123431417"]},{"id":"https://openalex.org/I150209017","display_name":"Scripps Institution of Oceanography","ror":"https://ror.org/04v7hvq31","country_code":"US","type":"facility","lineage":["https://openalex.org/I150209017","https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ravi Chawla","raw_affiliation_strings":["Department of Integrative Structural and Computational Biology, Scripps Research, La Jolla, CA","Department of Integrative Structural and Computational Biology, Scripps Research, La Jolla, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Integrative Structural and Computational Biology, Scripps Research, La Jolla, CA","institution_ids":["https://openalex.org/I150209017"]},{"raw_affiliation_string":"Department of Integrative Structural and Computational Biology, Scripps Research, La Jolla, California, USA","institution_ids":["https://openalex.org/I123431417"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016996120","display_name":"Steven Klupt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I123431417","display_name":"Scripps Research Institute","ror":"https://ror.org/02dxx6824","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I123431417"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven Klupt","raw_affiliation_strings":["Department of Immunology and Microbiology, Scripps Research, La Jolla, CA","Department of Immunology and Microbiology, Scripps Research, La Jolla, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology and Microbiology, Scripps Research, La Jolla, CA","institution_ids":["https://openalex.org/I123431417"]},{"raw_affiliation_string":"Department of Immunology and Microbiology, Scripps Research, La Jolla, California, USA","institution_ids":["https://openalex.org/I123431417"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028799736","display_name":"Vadim Patsalo","orcid":"https://orcid.org/0000-0001-6047-5858","observed_orcids":["https://orcid.org/0000-0001-6047-5858"]},"institutions":[{"id":"https://openalex.org/I123431417","display_name":"Scripps Research Institute","ror":"https://ror.org/02dxx6824","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I123431417"]},{"id":"https://openalex.org/I150209017","display_name":"Scripps Institution of Oceanography","ror":"https://ror.org/04v7hvq31","country_code":"US","type":"facility","lineage":["https://openalex.org/I150209017","https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vadim Patsalo","raw_affiliation_strings":["Department of Integrative Structural and Computational Biology, Scripps Research, La Jolla, CA","Department of Integrative Structural and Computational Biology, Scripps Research, La Jolla, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Integrative Structural and Computational Biology, Scripps Research, La Jolla, CA","institution_ids":["https://openalex.org/I150209017"]},{"raw_affiliation_string":"Department of Integrative Structural and Computational Biology, Scripps Research, La Jolla, California, USA","institution_ids":["https://openalex.org/I123431417"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074143608","display_name":"James R. Williamson","orcid":"https://orcid.org/0000-0002-8772-468X","observed_orcids":["https://orcid.org/0000-0002-8772-468X"]},"institutions":[{"id":"https://openalex.org/I123431417","display_name":"Scripps Research Institute","ror":"https://ror.org/02dxx6824","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I123431417"]},{"id":"https://openalex.org/I150209017","display_name":"Scripps Institution of Oceanography","ror":"https://ror.org/04v7hvq31","country_code":"US","type":"facility","lineage":["https://openalex.org/I150209017","https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James R Williamson","raw_affiliation_strings":["Department of Integrative Structural and Computational Biology, Scripps Research, La Jolla, CA","Department of Integrative Structural and Computational Biology, Scripps Research, La Jolla, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Integrative Structural and Computational Biology, Scripps Research, La Jolla, CA","institution_ids":["https://openalex.org/I150209017"]},{"raw_affiliation_string":"Department of Integrative Structural and Computational Biology, Scripps Research, La Jolla, California, USA","institution_ids":["https://openalex.org/I123431417"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019994285","display_name":"Lisa R. Racki","orcid":"https://orcid.org/0000-0003-2209-7301","observed_orcids":["https://orcid.org/0000-0003-2209-7301"]},"institutions":[{"id":"https://openalex.org/I123431417","display_name":"Scripps Research Institute","ror":"https://ror.org/02dxx6824","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I123431417"]},{"id":"https://openalex.org/I150209017","display_name":"Scripps Institution of Oceanography","ror":"https://ror.org/04v7hvq31","country_code":"US","type":"facility","lineage":["https://openalex.org/I150209017","https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Lisa R Racki","raw_affiliation_strings":["Department of Integrative Structural and Computational Biology, Scripps Research, La Jolla, CA","Department of Integrative Structural and Computational Biology, Scripps Research, La Jolla, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Integrative Structural and Computational Biology, Scripps Research, La Jolla, CA","institution_ids":["https://openalex.org/I150209017"]},{"raw_affiliation_string":"Department of Integrative Structural and Computational Biology, Scripps Research, La Jolla, California, USA","institution_ids":["https://openalex.org/I123431417"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5019994285"],"corresponding_institution_ids":["https://openalex.org/I123431417","https://openalex.org/I150209017"],"apc_list":{"value":3900,"currency":"USD","value_usd":3900},"apc_paid":{"value":3900,"currency":"USD","value_usd":3900},"fwci":1.6001,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":{"value":0.82805067,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"13","issue":"3","first_page":"e0246321","last_page":"e0246321"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.9872999787330627,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.9872999787330627,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10593","display_name":"Bacterial biofilms and quorum sensing","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12827","display_name":"Biochemical and Molecular Research","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/polyphosphate-granules","display_name":"polyphosphate granules","score":0.949999988079071},{"id":"https://openalex.org/keywords/pseudomonas-aeruginosa","display_name":"Pseudomonas aeruginosa","score":0.9169999957084656},{"id":"https://openalex.org/keywords/nitrogen-starvation","display_name":"nitrogen starvation","score":0.7210000157356262},{"id":"https://openalex.org/keywords/dna-binding-proteins","display_name":"DNA-binding proteins","score":0.8690000176429749},{"id":"https://openalex.org/keywords/alginate-biosynthesis","display_name":"alginate biosynthesis","score":0.6620000004768372},{"id":"https://openalex.org/keywords/bacterial-stress-response","display_name":"bacterial stress response","score":0.5770000219345093},{"id":"https://openalex.org/keywords/cystic-fibrosis","display_name":"cystic fibrosis","score":0.7860000133514404}],"concepts":[{"id":"https://openalex.org/C49760210","wikidata":"https://www.wikidata.org/wiki/Q5596727","display_name":"Granule (geology)","level":2,"score":0.8337357044219971},{"id":"https://openalex.org/C117838200","wikidata":"https://www.wikidata.org/wiki/Q14592582","display_name":"Stress granule","level":5,"score":0.7978235483169556},{"id":"https://openalex.org/C131934819","wikidata":"https://www.wikidata.org/wiki/Q135390","display_name":"Biogenesis","level":3,"score":0.6310528516769409},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5448848605155945},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.49171215295791626},{"id":"https://openalex.org/C162419368","wikidata":"https://www.wikidata.org/wiki/Q14864908","display_name":"P-bodies","level":5,"score":0.46164363622665405},{"id":"https://openalex.org/C64927066","wikidata":"https://www.wikidata.org/wiki/Q36293","display_name":"Histone","level":3,"score":0.4226924180984497},{"id":"https://openalex.org/C2778038992","wikidata":"https://www.wikidata.org/wiki/Q420783","display_name":"Polyphosphate","level":3,"score":0.4179970324039459},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.33882641792297363},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3289928436279297},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.08591726422309875},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C149364088","wikidata":"https://www.wikidata.org/wiki/Q185917","display_name":"Translation (biology)","level":4,"score":0.0},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.0},{"id":"https://openalex.org/C2777132085","wikidata":"https://www.wikidata.org/wiki/Q46220103","display_name":"Phosphate","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000464","descriptor_name":"Alginates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004268","descriptor_name":"DNA-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006657","descriptor_name":"Histones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011122","descriptor_name":"Polyphosphates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011550","descriptor_name":"Pseudomonas aeruginosa","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1128/mbio.02463-21","doi":"https://doi.org/10.1128/mbio.02463-21","is_oa":true,"landing_page_url":"https://doi.org/10.1128/mbio.02463-21","pdf_url":null,"source":{"id":"https://openalex.org/S4210201176","display_name":"mBio","issn_l":"2150-7511","issn":["2150-7511","2161-2129"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"mBio","raw_type":"journal-article"},{"id":"doi:10.1101/2021.08.24.457604","doi":"https://doi.org/10.1101/2021.08.24.457604","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2021.08.24.457604","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2021/09/01/2021.08.24.457604.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmh:oai:pubmedcentral.nih.gov:9239181","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9239181","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"mBio","raw_type":"Text"},{"id":"pmid:35435704","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35435704","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"mBio","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:704d8fcd6d724807a7fc9f0e7b110d97","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/704d8fcd6d724807a7fc9f0e7b110d97","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"mBio, Vol 13, Iss 3 (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1128/mbio.02463-21","doi":"https://doi.org/10.1128/mbio.02463-21","is_oa":true,"landing_page_url":"https://doi.org/10.1128/mbio.02463-21","pdf_url":null,"source":{"id":"https://openalex.org/S4210201176","display_name":"mBio","issn_l":"2150-7511","issn":["2150-7511","2161-2129"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"mBio","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G9000907936","display_name":"Dynamics of the Bacterial Ribosome and Proteome","funder_award_id":"R35GM136412","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320309839","display_name":"Donald E. and Delia B. Baxter Foundation","ror":"https://ror.org/03ht4bd53"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4226040427.pdf","grobid_xml":"https://content.openalex.org/works/W4226040427.grobid-xml"},"referenced_works_count":72,"referenced_works":["https://openalex.org/W89060019","https://openalex.org/W166323399","https://openalex.org/W1517832757","https://openalex.org/W1585136361","https://openalex.org/W1803102843","https://openalex.org/W1905036359","https://openalex.org/W1991716880","https://openalex.org/W2002201903","https://openalex.org/W2005663386","https://openalex.org/W2007325299","https://openalex.org/W2030985064","https://openalex.org/W2035608282","https://openalex.org/W2041871150","https://openalex.org/W2052953149","https://openalex.org/W2063433107","https://openalex.org/W2073708679","https://openalex.org/W2082222170","https://openalex.org/W2090723817","https://openalex.org/W2097281897","https://openalex.org/W2098852054","https://openalex.org/W2099412396","https://openalex.org/W2099659456","https://openalex.org/W2102321085","https://openalex.org/W2105858723","https://openalex.org/W2108403115","https://openalex.org/W2112245854","https://openalex.org/W2121063712","https://openalex.org/W2126970339","https://openalex.org/W2134339806","https://openalex.org/W2144235436","https://openalex.org/W2145490060","https://openalex.org/W2159786375","https://openalex.org/W2167279371","https://openalex.org/W2172287360","https://openalex.org/W2179324586","https://openalex.org/W2265030692","https://openalex.org/W2291667497","https://openalex.org/W2473503437","https://openalex.org/W2531343081","https://openalex.org/W2580717269","https://openalex.org/W2594398579","https://openalex.org/W2766203511","https://openalex.org/W2901009838","https://openalex.org/W2905220927","https://openalex.org/W2908060926","https://openalex.org/W2912413857","https://openalex.org/W2918929528","https://openalex.org/W2946711651","https://openalex.org/W2949571561","https://openalex.org/W2951727057","https://openalex.org/W2990925487","https://openalex.org/W2999515100","https://openalex.org/W3003257820","https://openalex.org/W3006312769","https://openalex.org/W3019766797","https://openalex.org/W3034680017","https://openalex.org/W3036811605","https://openalex.org/W3040400978","https://openalex.org/W3041115542","https://openalex.org/W3043530209","https://openalex.org/W3047919496","https://openalex.org/W3091174223","https://openalex.org/W3098766606","https://openalex.org/W3120620398","https://openalex.org/W3121006590","https://openalex.org/W3128261063","https://openalex.org/W3177828909","https://openalex.org/W3181802031","https://openalex.org/W3186552365","https://openalex.org/W3211795435","https://openalex.org/W4200210198","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W4319880582","https://openalex.org/W2594398579","https://openalex.org/W7042507740","https://openalex.org/W2082222170","https://openalex.org/W2126970339","https://openalex.org/W1504232702","https://openalex.org/W2265030692","https://openalex.org/W1848823630","https://openalex.org/W3120620398","https://openalex.org/W1982796697"],"abstract_inverted_index":{"ABSTRACT":[0],"Synthesis":[1],"of":[2,42,49,59,124,145,158,173,247,271,278,311,353,368,381,396,403],"polyphosphate":[3],"(polyP)":[4],"is":[5,118,128,178,370,383],"an":[6,149,313],"ancient":[7],"and":[8,11,56,143,165,187,237],"universal":[9],"stress":[10],"starvation":[12,45,81,263],"response":[13],"in":[14,44,82,140,170,300,317,321,330,348,399],"bacteria.":[15],"In":[16,360],"many":[17],"bacteria,":[18],"polyP":[19,34,43,99,111,125,205,284,297],"chains":[20],"come":[21],"together":[22],"to":[23,32,96,154,180,201,207,229,242],"form":[24],"granular":[25],"superstructures":[26,287],"within":[27],"cells.":[28],"Some":[29],"species":[30],"appear":[31],"regulate":[33],"granule":[35,221,232,248,286,292,386],"subcellular":[36,351],"organization.":[37],"Despite":[38],"the":[39,47,75,83,121,155,171,182,208,226,244,350,364,379,389,393,400],"critical":[40],"role":[41,329],"fitness,":[46],"composition":[48,152],"these":[50,397],"structures,":[51],"mechanism(s)":[52],"underpinning":[53,257],"their":[54],"organization,":[55],"functional":[57,245,394],"significance":[58,246,395],"such":[60],"organization":[61,249,352,387],"are":[62,167],"poorly":[63],"understood.":[64],"We":[65,102,113,195,339],"previously":[66,343],"determined":[67],"that":[68,108,116,197,218,378],"granules":[69,206],"become":[70],"transiently":[71],"evenly":[72],"spaced":[73],"on":[74,250,261],"cell\u2019s":[76],"long":[77],"axis":[78],"during":[79,252],"nitrogen":[80],"opportunistic":[84],"human":[85],"pathogen":[86],"Pseudomonas":[87,301],"aeruginosa":[88,302],".":[89],"Here,":[90],"we":[91],"developed":[92],"a":[93,106,129,133,296,341,371],"granule-enrichment":[94],"protocol":[95,294],"screen":[97],"for":[98,120,225,346,358,373,385,391],"granule-localizing":[100],"proteins.":[101,282],"identified":[103,295],"AlgP":[104,117,127,177,198,219,305,347,369,382],"as":[105,309],"protein":[107,131,272,299],"associates":[109],"with":[110,132,148,213,288],"granules.":[112,126,194,215],"further":[114],"discovered":[115],"required":[119,384],"even":[122,235],"spacing":[123,166,202,222],"DNA-binding":[130],"154":[134],"amino":[135],"acid":[136],"C-terminal":[137,156,365],"domain":[138,367],"enriched":[139],"\u2018KPAA\u2019":[141],"repeats":[142],"variants":[144],"this":[146],"repeat,":[147],"overall":[150],"sequence":[151],"similar":[153],"tail":[157],"eukaryotic":[159],"histone":[160],"H1.":[161],"Granule":[162],"size,":[163],"number,":[164],"significantly":[168],"perturbed":[169],"absence":[172],"AlgP,":[174],"or":[175],"when":[176],"truncated":[179],"remove":[181],"C-terminus.":[183],"The":[184,255],"\u0394":[185],"algP":[186,188],"\u0394CTD":[189],"mutants":[190],"having":[191],"fewer,":[192],"larger":[193],"speculate":[196],"may":[199],"contribute":[200],"by":[203],"tethering":[204],"chromosome,":[209],"thereby":[210],"inhibiting":[211],"fusion":[212],"neighboring":[214],"Our":[216,291,376],"discovery":[217],"facilitates":[220],"allows":[223],"us":[224],"first":[227],"time":[228],"directly":[230],"uncouple":[231],"biogenesis":[233],"from":[234],"spacing,":[236],"will":[238],"inform":[239],"future":[240],"efforts":[241],"explore":[243],"fitness":[251],"starvation.":[253],"IMPORTANCE":[254],"mechanisms":[256],"polyP\u2019s":[258],"pleiotropic":[259],"effects":[260],"bacterial":[262],"physiology":[264],"remain":[265],"elusive.":[266],"This":[267],"simple":[268],"polyanion\u2019s":[269],"lack":[270],"binding":[273],"specificity":[274],"has":[275,333],"impeded":[276],"validation":[277],"bona":[279],"fide":[280],"polyP-binding":[281],"However,":[283],"forms":[285],"spatial":[289],"specificity.":[290],"enrichment":[293],"granule-associated":[298],",":[303],"AlgP.":[304],"was":[306],"originally":[307],"reported":[308],"regulator":[310],"alginate,":[312],"extracellular":[314],"polysaccharide":[315],"important":[316,357],"biofilm":[318],"formation,":[319],"including":[320],"cystic":[322],"fibrosis":[323],"(CF)":[324],"chronic":[325,404],"infections.":[326,405],"AlgP\u2019s":[327],"putative":[328],"alginate":[331],"biosynthesis":[332],"recently":[334],"been":[335],"called":[336],"into":[337],"question.":[338],"establish":[340],"distinct,":[342],"unknown":[344],"function":[345],"modulating":[349],"polyP,":[354],"another":[355],"polymer":[356],"pathogenesis.":[359],"CF":[361],"clinical":[362],"isolates,":[363],"repeat":[366],"hotspot":[372],"genetic":[374],"rearrangements.":[375],"finding":[377],"C-terminus":[380],"lays":[388],"groundwork":[390],"exploring":[392],"mutations":[398],"evolutionary":[401],"trajectory":[402]},"counts_by_year":[{"year":2026,"cited_by_count":10},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":7},{"year":2022,"cited_by_count":1}],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2022-05-05T00:00:00"}
