{"id":"https://openalex.org/W4225420194","doi":"https://doi.org/10.1096/fasebj.2022.36.s1.r3905","title":"A Novel Technique to Reduce Kidney Injury by Maintaining Na/K Pump Functions Using Electric Energy","display_name":"A Novel Technique to Reduce Kidney Injury by Maintaining Na/K Pump Functions Using Electric Energy","publication_year":2022,"publication_date":"2022-05-01","ids":{"openalex":"https://openalex.org/W4225420194","doi":"https://doi.org/10.1096/fasebj.2022.36.s1.r3905"},"language":"en","primary_location":{"id":"doi:10.1096/fasebj.2022.36.s1.r3905","doi":"https://doi.org/10.1096/fasebj.2022.36.s1.r3905","is_oa":false,"landing_page_url":"https://doi.org/10.1096/fasebj.2022.36.s1.r3905","pdf_url":null,"source":{"id":"https://openalex.org/S25293849","display_name":"The FASEB Journal","issn_l":"0892-6638","issn":["0892-6638","1530-6860"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The FASEB Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100435912","display_name":"Lei Wang","orcid":"https://orcid.org/0000-0002-3778-2814","observed_orcids":["https://orcid.org/0000-0002-3778-2814"]},"institutions":[{"id":"https://openalex.org/I2613432","display_name":"University of South Florida","ror":"https://ror.org/032db5x82","country_code":"US","type":"education","lineage":["https://openalex.org/I2613432"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lei Wang","raw_affiliation_strings":["University of South Florida, Tampa, FL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of South Florida, Tampa, FL","institution_ids":["https://openalex.org/I2613432"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100344443","display_name":"Wei Chen","orcid":"https://orcid.org/0000-0002-5080-095X","observed_orcids":["https://orcid.org/0000-0002-5080-095X"]},"institutions":[{"id":"https://openalex.org/I2613432","display_name":"University of South Florida","ror":"https://ror.org/032db5x82","country_code":"US","type":"education","lineage":["https://openalex.org/I2613432"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wei Chen","raw_affiliation_strings":["University of South Florida, Tampa, FL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of South Florida, Tampa, FL","institution_ids":["https://openalex.org/I2613432"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066990458","display_name":"Pengfei Liang","orcid":"https://orcid.org/0000-0001-5128-1509","observed_orcids":["https://orcid.org/0000-0001-5128-1509"]},"institutions":[{"id":"https://openalex.org/I2613432","display_name":"University of South Florida","ror":"https://ror.org/032db5x82","country_code":"US","type":"education","lineage":["https://openalex.org/I2613432"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pengfei Liang","raw_affiliation_strings":["University of South Florida, Tampa, FL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of South Florida, Tampa, FL","institution_ids":["https://openalex.org/I2613432"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040630385","display_name":"Jin Wei","orcid":"https://orcid.org/0000-0001-8040-8126","observed_orcids":["https://orcid.org/0000-0001-8040-8126"]},"institutions":[{"id":"https://openalex.org/I2613432","display_name":"University of South Florida","ror":"https://ror.org/032db5x82","country_code":"US","type":"education","lineage":["https://openalex.org/I2613432"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jin Wei","raw_affiliation_strings":["University of South Florida, Tampa, FL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of South Florida, Tampa, FL","institution_ids":["https://openalex.org/I2613432"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100436618","display_name":"Jie Zhang","orcid":"https://orcid.org/0000-0001-6717-4118","observed_orcids":["https://orcid.org/0000-0001-6717-4118"]},"institutions":[{"id":"https://openalex.org/I2613432","display_name":"University of South Florida","ror":"https://ror.org/032db5x82","country_code":"US","type":"education","lineage":["https://openalex.org/I2613432"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jie Zhang","raw_affiliation_strings":["University of South Florida, Tampa, FL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of South Florida, Tampa, FL","institution_ids":["https://openalex.org/I2613432"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012014330","display_name":"Jacentha Buggs","orcid":"https://orcid.org/0000-0002-2709-7530","observed_orcids":["https://orcid.org/0000-0002-2709-7530"]},"institutions":[{"id":"https://openalex.org/I2801973574","display_name":"Tampa General Hospital","ror":"https://ror.org/03tj5qd85","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801973574"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jacentha Buggs","raw_affiliation_strings":["Tampa General Hospital, Tampa, FL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tampa General Hospital, Tampa, FL","institution_ids":["https://openalex.org/I2801973574"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045686015","display_name":"Ruisheng Liu","orcid":"https://orcid.org/0000-0002-2220-1888","observed_orcids":["https://orcid.org/0000-0002-2220-1888"]},"institutions":[{"id":"https://openalex.org/I2613432","display_name":"University of South Florida","ror":"https://ror.org/032db5x82","country_code":"US","type":"education","lineage":["https://openalex.org/I2613432"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ruisheng Liu","raw_affiliation_strings":["University of South Florida, Tampa, FL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of South Florida, Tampa, FL","institution_ids":["https://openalex.org/I2613432"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3200,"currency":"USD","value_usd":3200},"apc_paid":null,"fwci":0.1613,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.41803235,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"36","issue":"S1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":0.6815999746322632,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":0.6815999746322632,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10999","display_name":"Organ Transplantation Techniques and Outcomes","score":0.1940000057220459,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.02459999918937683,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/renal-ischemia-reperfusion-injury","display_name":"renal ischemia-reperfusion injury","score":0.9710000157356262},{"id":"https://openalex.org/keywords/na-k-atpase","display_name":"Na+/K+-ATPase","score":0.7239999771118164},{"id":"https://openalex.org/keywords/atp-depletion","display_name":"ATP depletion","score":0.6110000014305115},{"id":"https://openalex.org/keywords/oscillating-electric-field","display_name":"oscillating electric field","score":0.8100000023841858},{"id":"https://openalex.org/keywords/kidney-transplantation","display_name":"kidney transplantation","score":0.8109999895095825},{"id":"https://openalex.org/keywords/delayed-graft-function","display_name":"delayed graft function","score":0.8790000081062317},{"id":"https://openalex.org/keywords/cold-ischemia","display_name":"cold ischemia","score":0.9200000166893005},{"id":"https://openalex.org/keywords/warm-ischemia","display_name":"warm ischemia","score":0.9599999785423279},{"id":"https://openalex.org/keywords/renal-allograft-function","display_name":"renal allograft function","score":0.7020000219345093}],"concepts":[{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.746128499507904},{"id":"https://openalex.org/C159641895","wikidata":"https://www.wikidata.org/wiki/Q108377937","display_name":"Renal function","level":2,"score":0.6221224069595337},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.5642032623291016},{"id":"https://openalex.org/C2780306776","wikidata":"https://www.wikidata.org/wiki/Q426660","display_name":"Creatinine","level":2,"score":0.45837876200675964},{"id":"https://openalex.org/C60799052","wikidata":"https://www.wikidata.org/wiki/Q46221","display_name":"Electric field","level":2,"score":0.4509614408016205},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.45045381784439087},{"id":"https://openalex.org/C2780114680","wikidata":"https://www.wikidata.org/wiki/Q1413991","display_name":"Reperfusion injury","level":3,"score":0.44911324977874756},{"id":"https://openalex.org/C2780472472","wikidata":"https://www.wikidata.org/wiki/Q424337","display_name":"Acute kidney injury","level":2,"score":0.44727733731269836},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3883787989616394},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.11153948307037354},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1096/fasebj.2022.36.s1.r3905","doi":"https://doi.org/10.1096/fasebj.2022.36.s1.r3905","is_oa":false,"landing_page_url":"https://doi.org/10.1096/fasebj.2022.36.s1.r3905","pdf_url":null,"source":{"id":"https://openalex.org/S25293849","display_name":"The FASEB Journal","issn_l":"0892-6638","issn":["0892-6638","1530-6860"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The FASEB Journal","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4397046733","https://openalex.org/W4220749078","https://openalex.org/W7113203938","https://openalex.org/W7223109897","https://openalex.org/W4397040916","https://openalex.org/W4412865859","https://openalex.org/W2090221828","https://openalex.org/W2622762925","https://openalex.org/W2621537567","https://openalex.org/W2172901384"],"abstract_inverted_index":{"Renal":[0],"ischemia\u2010reperfusion":[1,150],"injury":[2,64,151,191],"is":[3,15,35],"an":[4,77,146],"important":[5],"contributor":[6],"to":[7,81,112],"the":[8,26,30,60,84,98,119,132,172,220],"development":[9],"of":[10,25,29,62,108,134,140,142,171,197,248],"delayed":[11,178],"graft":[12],"function,":[13],"which":[14,42],"associated":[16,245],"with":[17,219,246],"higher":[18],"rejection":[19],"rates":[20],"and":[21,87,117,156,160,183,199,206,210],"worse":[22],"long\u2010term":[23],"outcomes":[24],"allografts.":[27],"One":[28],"earliest":[31],"impairments":[32],"during":[33,65,181],"ischemia":[34,182],"insufficient":[36,128],"ATP":[37,52,127,179],"supply\u2010induced":[38],"Na/K":[39,55,185,227,249],"pump":[40,56,85,186,228],"dysfunction,":[41],"results":[43,167],"in":[44,115,137,147],"subsequent":[45],"cellular":[46,124],"damage.":[47],"Consequently,":[48],"strategies":[49],"that":[50,75,169],"preserve":[51],"levels":[53],"or":[54],"function":[57,214,229],"may":[58,230],"limit":[59],"extent":[61],"renal":[63,144,149,212],"ischemia\u2010reperfusion.":[66],"In":[67],"this":[68,95,105,135],"study,":[69],"we":[70],"developed":[71],"a":[72],"novel":[73,106,223],"technique":[74,96,107,136,224],"applies":[76],"oscillating":[78],"electrical":[79],"field":[80,176,204],"first":[82],"synchronize":[83],"molecules,":[86],"then":[88],"modulate":[89],"their":[90],"pumping":[91],"rates.":[92],"We":[93,103,130],"dubbed":[94],"as":[97],"synchronization":[99],"modulation":[100],"electric":[101,110,175,203],"field.":[102],"present":[104],"using":[109],"energy":[111],"substitute":[113],"ATPs":[114],"fueling":[116],"activating":[118],"pumps,":[120],"thereby":[121,188],"efficiently":[122],"maintaining":[123],"functions":[125],"under":[126],"conditions.":[129],"tested":[131],"effectiveness":[133],"two":[138],"kinds":[139],"models":[141,162],"ischemic":[143,237],"injury:":[145],"situ":[148],"model":[152],"(predominantly":[153,163],"warm":[154],"ischemia)":[155],"kidney":[157,190,238],"transplantation":[158],"rodent":[159],"swine":[161],"cold":[164],"ischemia).":[165],"Our":[166],"show":[168],"application":[170],"specially":[173],"designed":[174],"effectively":[177],"depletion":[180],"preserves":[184],"activity,":[187],"alleviating":[189],"by":[192,215],"about":[193],"45%":[194],"(plasma":[195],"creatinine":[196],"1.17\u00b10.04":[198],"1.97\u00b10.06":[200],"mg/dL":[201],"for":[202,225,236,242],"treated":[205],"untreated":[207],"groups,":[208],"respectively)":[209],"improving":[211],"allograft":[213],"over":[216],"50%":[217],"compared":[218],"controls.":[221],"This":[222],"preserving":[226],"have":[231],"therapeutic":[232],"potential":[233],"not":[234],"only":[235],"injury,":[239],"but":[240],"also":[241],"other":[243],"diseases":[244],"dysfunction":[247],"pumps.":[250]},"counts_by_year":[{"year":2024,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2022-05-05T00:00:00"}