{"id":"https://openalex.org/W4224313809","doi":"https://doi.org/10.1002/anbr.202100083","title":"Isolation of Circulating Tumor Cells to Diagnose Melanoma and Evaluate the Efficacy of Surgical Resection Using Melanoma\u2010Specific Microsystem","display_name":"Isolation of Circulating Tumor Cells to Diagnose Melanoma and Evaluate the Efficacy of Surgical Resection Using Melanoma\u2010Specific Microsystem","publication_year":2022,"publication_date":"2022-04-19","ids":{"openalex":"https://openalex.org/W4224313809","doi":"https://doi.org/10.1002/anbr.202100083","pmid":"https://pubmed.ncbi.nlm.nih.gov/36591389"},"language":"en","primary_location":{"id":"doi:10.1002/anbr.202100083","doi":"https://doi.org/10.1002/anbr.202100083","is_oa":true,"landing_page_url":"https://doi.org/10.1002/anbr.202100083","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/anbr.202100083","source":{"id":"https://openalex.org/S4210232512","display_name":"Advanced NanoBiomed Research","issn_l":"2699-9307","issn":["2699-9307"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","norway-1","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advanced NanoBiomed Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/anbr.202100083","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038440270","display_name":"Yoon\u2010Tae Kang","orcid":"https://orcid.org/0000-0003-1596-7815","observed_orcids":["https://orcid.org/0000-0003-1596-7815"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yoon-Tae Kang","raw_affiliation_strings":["Department of Chemical Engineering and Biointerface Institute University of Michigan  2800 Plymouth Road, NCRC B10-A184 Ann Arbor MI 48109 USA","Department of Chemical Engineering and Biointerface Institute, University of Michigan, 2800 Plymouth Road, NCRC B10-A184, Ann Arbor, MI, 48109 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering and Biointerface Institute University of Michigan  2800 Plymouth Road, NCRC B10-A184 Ann Arbor MI 48109 USA","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Department of Chemical Engineering and Biointerface Institute, University of Michigan, 2800 Plymouth Road, NCRC B10-A184, Ann Arbor, MI, 48109 USA","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047267418","display_name":"Anusha Mutukuri","orcid":"https://orcid.org/0000-0002-1260-2602","observed_orcids":["https://orcid.org/0000-0002-1260-2602"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anusha Mutukuri","raw_affiliation_strings":["Department of Chemical Engineering and Biointerface Institute University of Michigan  2800 Plymouth Road, NCRC B10-A184 Ann Arbor MI 48109 USA","Department of Chemical Engineering and Biointerface Institute, University of Michigan, 2800 Plymouth Road, NCRC B10-A184, Ann Arbor, MI, 48109 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering and Biointerface Institute University of Michigan  2800 Plymouth Road, NCRC B10-A184 Ann Arbor MI 48109 USA","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Department of Chemical Engineering and Biointerface Institute, University of Michigan, 2800 Plymouth Road, NCRC B10-A184, Ann Arbor, MI, 48109 USA","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062938403","display_name":"Thomas Hadlock","orcid":"https://orcid.org/0000-0002-9123-4982","observed_orcids":["https://orcid.org/0000-0002-9123-4982"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas Hadlock","raw_affiliation_strings":["Department of Chemical Engineering and Biointerface Institute University of Michigan  2800 Plymouth Road, NCRC B10-A184 Ann Arbor MI 48109 USA","Department of Chemical Engineering and Biointerface Institute, University of Michigan, 2800 Plymouth Road, NCRC B10-A184, Ann Arbor, MI, 48109 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering and Biointerface Institute University of Michigan  2800 Plymouth Road, NCRC B10-A184 Ann Arbor MI 48109 USA","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Department of Chemical Engineering and Biointerface Institute, University of Michigan, 2800 Plymouth Road, NCRC B10-A184, Ann Arbor, MI, 48109 USA","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048549824","display_name":"Heather Fairbairn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Heather Fairbairn","raw_affiliation_strings":["Department of Chemical Engineering and Biointerface Institute University of Michigan  2800 Plymouth Road, NCRC B10-A184 Ann Arbor MI 48109 USA","Department of Chemical Engineering and Biointerface Institute, University of Michigan, 2800 Plymouth Road, NCRC B10-A184, Ann Arbor, MI, 48109 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering and Biointerface Institute University of Michigan  2800 Plymouth Road, NCRC B10-A184 Ann Arbor MI 48109 USA","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Department of Chemical Engineering and Biointerface Institute, University of Michigan, 2800 Plymouth Road, NCRC B10-A184, Ann Arbor, MI, 48109 USA","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086990114","display_name":"Taylor R. Carle","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]},{"id":"https://openalex.org/I4210111446","display_name":"A. Alfred Taubman Health Care Center","ror":"https://ror.org/01rh00978","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210111446","https://openalex.org/I4210114445"]},{"id":"https://openalex.org/I4210114445","display_name":"Michigan Medicine","ror":"https://ror.org/01zcpa714","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210114445"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Taylor R. Carle","raw_affiliation_strings":["Michigan Medicine Otolaryngology Clinic Taubman Center University of Michigan  Ann Arbor MI 48109 USA","Michigan Medicine Otolaryngology Clinic, Taubman Center, University of Michigan, Ann Arbor, MI, 48109 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Michigan Medicine Otolaryngology Clinic Taubman Center University of Michigan  Ann Arbor MI 48109 USA","institution_ids":["https://openalex.org/I27837315","https://openalex.org/I4210111446","https://openalex.org/I4210114445"]},{"raw_affiliation_string":"Michigan Medicine Otolaryngology Clinic, Taubman Center, University of Michigan, Ann Arbor, MI, 48109 USA","institution_ids":["https://openalex.org/I27837315","https://openalex.org/I4210111446","https://openalex.org/I4210114445"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111631979","display_name":"Shamileh Fouladdel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shamileh Fouladdel","raw_affiliation_strings":["Department of Chemical Engineering and Biointerface Institute University of Michigan  2800 Plymouth Road, NCRC B10-A184 Ann Arbor MI 48109 USA","Department of Chemical Engineering and Biointerface Institute, University of Michigan, 2800 Plymouth Road, NCRC B10-A184, Ann Arbor, MI, 48109 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering and Biointerface Institute University of Michigan  2800 Plymouth Road, NCRC B10-A184 Ann Arbor MI 48109 USA","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Department of Chemical Engineering and Biointerface Institute, University of Michigan, 2800 Plymouth Road, NCRC B10-A184, Ann Arbor, MI, 48109 USA","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104109530","display_name":"Vasudha Murlidhar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vasudha Murlidhar","raw_affiliation_strings":["Department of Chemical Engineering and Biointerface Institute University of Michigan  2800 Plymouth Road, NCRC B10-A184 Ann Arbor MI 48109 USA","Department of Chemical Engineering and Biointerface Institute, University of Michigan, 2800 Plymouth Road, NCRC B10-A184, Ann Arbor, MI, 48109 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering and Biointerface Institute University of Michigan  2800 Plymouth Road, NCRC B10-A184 Ann Arbor MI 48109 USA","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Department of Chemical Engineering and Biointerface Institute, University of Michigan, 2800 Plymouth Road, NCRC B10-A184, Ann Arbor, MI, 48109 USA","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001410650","display_name":"Aaron Kramer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aaron Kramer","raw_affiliation_strings":["Department of Chemical Engineering and Biointerface Institute University of Michigan  2800 Plymouth Road, NCRC B10-A184 Ann Arbor MI 48109 USA","Department of Chemical Engineering and Biointerface Institute, University of Michigan, 2800 Plymouth Road, NCRC B10-A184, Ann Arbor, MI, 48109 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering and Biointerface Institute University of Michigan  2800 Plymouth Road, NCRC B10-A184 Ann Arbor MI 48109 USA","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Department of Chemical Engineering and Biointerface Institute, University of Michigan, 2800 Plymouth Road, NCRC B10-A184, Ann Arbor, MI, 48109 USA","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043242745","display_name":"Monica De Reguera","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Monica De Silva Reguera","raw_affiliation_strings":["Department of Chemical Engineering and Biointerface Institute University of Michigan  2800 Plymouth Road, NCRC B10-A184 Ann Arbor MI 48109 USA","Department of Chemical Engineering and Biointerface Institute, University of Michigan, 2800 Plymouth Road, NCRC B10-A184, Ann Arbor, MI, 48109 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering and Biointerface Institute University of Michigan  2800 Plymouth Road, NCRC B10-A184 Ann Arbor MI 48109 USA","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Department of Chemical Engineering and Biointerface Institute, University of Michigan, 2800 Plymouth Road, NCRC B10-A184, Ann Arbor, MI, 48109 USA","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111428064","display_name":"Ebrahim Azizi","orcid":"https://orcid.org/0000-0002-0230-2534","observed_orcids":["https://orcid.org/0000-0002-0230-2534"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ebrahim Azizi","raw_affiliation_strings":["Biointerfaces Institute (BI) Translational Oncology Program (TOP) Department of Internal Medicine University of Michigan  2800 Plymouth Road Ann Arbor MI 48109 USA","Biointerfaces Institute (BI), Translational Oncology Program (TOP), Department of Internal Medicine, University of Michigan, 2800 Plymouth Road, Ann Arbor, MI, 48109 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biointerfaces Institute (BI) Translational Oncology Program (TOP) Department of Internal Medicine University of Michigan  2800 Plymouth Road Ann Arbor MI 48109 USA","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Biointerfaces Institute (BI), Translational Oncology Program (TOP), Department of Internal Medicine, University of Michigan, 2800 Plymouth Road, Ann Arbor, MI, 48109 USA","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068146420","display_name":"Alison B. Durham","orcid":"https://orcid.org/0000-0002-5051-5374","observed_orcids":["https://orcid.org/0000-0002-5051-5374"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]},{"id":"https://openalex.org/I4210111446","display_name":"A. Alfred Taubman Health Care Center","ror":"https://ror.org/01rh00978","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210111446","https://openalex.org/I4210114445"]},{"id":"https://openalex.org/I4210114445","display_name":"Michigan Medicine","ror":"https://ror.org/01zcpa714","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210114445"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alison Durham","raw_affiliation_strings":["Michigan Medicine Otolaryngology Clinic Taubman Center University of Michigan  Ann Arbor MI 48109 USA","Michigan Medicine Otolaryngology Clinic, Taubman Center, University of Michigan, Ann Arbor, MI, 48109 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Michigan Medicine Otolaryngology Clinic Taubman Center University of Michigan  Ann Arbor MI 48109 USA","institution_ids":["https://openalex.org/I27837315","https://openalex.org/I4210111446","https://openalex.org/I4210114445"]},{"raw_affiliation_string":"Michigan Medicine Otolaryngology Clinic, Taubman Center, University of Michigan, Ann Arbor, MI, 48109 USA","institution_ids":["https://openalex.org/I27837315","https://openalex.org/I4210111446","https://openalex.org/I4210114445"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001968662","display_name":"Scott Alan McLean","orcid":"https://orcid.org/0000-0002-1884-6632","observed_orcids":["https://orcid.org/0000-0002-1884-6632"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]},{"id":"https://openalex.org/I4210111446","display_name":"A. Alfred Taubman Health Care Center","ror":"https://ror.org/01rh00978","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210111446","https://openalex.org/I4210114445"]},{"id":"https://openalex.org/I4210114445","display_name":"Michigan Medicine","ror":"https://ror.org/01zcpa714","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210114445"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Scott A. Mclean","raw_affiliation_strings":["Michigan Medicine Otolaryngology Clinic Taubman Center University of Michigan  Ann Arbor MI 48109 USA","Michigan Medicine Otolaryngology Clinic, Taubman Center, University of Michigan, Ann Arbor, MI, 48109 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Michigan Medicine Otolaryngology Clinic Taubman Center University of Michigan  Ann Arbor MI 48109 USA","institution_ids":["https://openalex.org/I27837315","https://openalex.org/I4210111446","https://openalex.org/I4210114445"]},{"raw_affiliation_string":"Michigan Medicine Otolaryngology Clinic, Taubman Center, University of Michigan, Ann Arbor, MI, 48109 USA","institution_ids":["https://openalex.org/I27837315","https://openalex.org/I4210111446","https://openalex.org/I4210114445"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008169438","display_name":"Sunitha Nagrath","orcid":"https://orcid.org/0000-0002-1497-7977","observed_orcids":["https://orcid.org/0000-0002-1497-7977"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sunitha Nagrath","raw_affiliation_strings":["Department of Chemical Engineering and Biointerface Institute University of Michigan  2800 Plymouth Road, NCRC B10-A184 Ann Arbor MI 48109 USA","Roger Cancer Center University of Michigan  1500 E Medical Center Dr Ann Arbor MI 48109 USA","Department of Chemical Engineering and Biointerface Institute, University of Michigan, 2800 Plymouth Road, NCRC B10-A184, Ann Arbor, MI, 48109 USA","Roger Cancer Center, University of Michigan, 1500 E Medical Center Dr, Ann Arbor, MI, 48109 USA"],"raw_orcid":"https://orcid.org/0000-0002-1497-7977","affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering and Biointerface Institute University of Michigan  2800 Plymouth Road, NCRC B10-A184 Ann Arbor MI 48109 USA","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Roger Cancer Center University of Michigan  1500 E Medical Center Dr Ann Arbor MI 48109 USA","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Department of Chemical Engineering and Biointerface Institute, University of Michigan, 2800 Plymouth Road, NCRC B10-A184, Ann Arbor, MI, 48109 USA","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Roger Cancer Center, University of Michigan, 1500 E Medical Center Dr, Ann Arbor, MI, 48109 USA","institution_ids":["https://openalex.org/I27837315"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5001968662","https://openalex.org/A5008169438"],"corresponding_institution_ids":["https://openalex.org/I27837315","https://openalex.org/I4210111446","https://openalex.org/I4210114445"],"apc_list":{"value":3500,"currency":"USD","value_usd":3500},"apc_paid":{"value":3500,"currency":"USD","value_usd":3500},"fwci":0.6756,"has_fulltext":true,"cited_by_count":12,"citation_normalized_percentile":{"value":0.59583787,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"2","issue":"8","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11255","display_name":"Microfluidic and Bio-sensing Technologies","score":0.3353999853134155,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11255","display_name":"Microfluidic and Bio-sensing Technologies","score":0.3353999853134155,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10392","display_name":"Cutaneous Melanoma Detection and Management","score":0.2046000063419342,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.09830000251531601,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/melanoma","display_name":"melanoma","score":0.8880000114440918},{"id":"https://openalex.org/keywords/circulating-tumor-cells","display_name":"circulating tumor cells","score":1.0},{"id":"https://openalex.org/keywords/liquid-biopsy","display_name":"liquid biopsy","score":0.7739999890327454},{"id":"https://openalex.org/keywords/ctc-clusters","display_name":"CTC clusters","score":0.7639999985694885},{"id":"https://openalex.org/keywords/molecular-profiling","display_name":"molecular profiling","score":0.5180000066757202},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.7749999761581421},{"id":"https://openalex.org/keywords/metastasis","display_name":"metastasis","score":0.6330000162124634}],"concepts":[{"id":"https://openalex.org/C2777658100","wikidata":"https://www.wikidata.org/wiki/Q180614","display_name":"Melanoma","level":2,"score":0.8973326683044434},{"id":"https://openalex.org/C61238886","wikidata":"https://www.wikidata.org/wiki/Q5121689","display_name":"Circulating tumor cell","level":4,"score":0.8342702388763428},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7280744314193726},{"id":"https://openalex.org/C2779529041","wikidata":"https://www.wikidata.org/wiki/Q22349364","display_name":"Liquid biopsy","level":3,"score":0.5719856023788452},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.5499187111854553},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.49397069215774536},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.46139049530029297},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.45084574818611145},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.41005200147628784},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.40397804975509644},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.36038637161254883}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1002/anbr.202100083","doi":"https://doi.org/10.1002/anbr.202100083","is_oa":true,"landing_page_url":"https://doi.org/10.1002/anbr.202100083","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/anbr.202100083","source":{"id":"https://openalex.org/S4210232512","display_name":"Advanced NanoBiomed Research","issn_l":"2699-9307","issn":["2699-9307"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","norway-1","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advanced NanoBiomed Research","raw_type":"journal-article"},{"id":"pmid:36591389","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36591389","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advanced nanobiomed research","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9797203","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9797203","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Adv Nanobiomed Res","raw_type":"Text"},{"id":"pmh:oai:deepblue.lib.umich.edu:2027.42/174835","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/2027.42/174835","pdf_url":null,"source":{"id":"https://openalex.org/S4306400393","display_name":"Deep Blue (University of Michigan)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I27837315","host_organization_name":"University of Michigan","host_organization_lineage":["https://openalex.org/I27837315"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"pmh:oai:doaj.org/article:6ead52aedc5d4865a54a7d6db9e91e25","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/6ead52aedc5d4865a54a7d6db9e91e25","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Advanced NanoBiomed Research, Vol 2, Iss 8, Pp n/a-n/a (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1002/anbr.202100083","doi":"https://doi.org/10.1002/anbr.202100083","is_oa":true,"landing_page_url":"https://doi.org/10.1002/anbr.202100083","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/anbr.202100083","source":{"id":"https://openalex.org/S4210232512","display_name":"Advanced NanoBiomed Research","issn_l":"2699-9307","issn":["2699-9307"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","norway-1","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advanced NanoBiomed Research","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.8199999928474426,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G1599055349","display_name":null,"funder_award_id":"UL1TR002240","funder_id":"https://openalex.org/F4320316438","funder_display_name":"Georgia Clinical and Translational Science Alliance"},{"id":"https://openalex.org/G1955162086","display_name":null,"funder_award_id":"R33 CA202867","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G2049072053","display_name":null,"funder_award_id":"UL1TR002240","funder_id":"https://openalex.org/F4320309652","funder_display_name":"University of Michigan"},{"id":"https://openalex.org/G2840467061","display_name":null,"funder_award_id":"CTSA: UL1TR002240","funder_id":"https://openalex.org/F4320309652","funder_display_name":"University of Michigan"},{"id":"https://openalex.org/G3021420554","display_name":"Label free microfluidic isolation, characterization and ex vivo expansion of CTCs","funder_award_id":"R01CA208335","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G319125330","display_name":null,"funder_award_id":"DMR-0320740","funder_id":"https://openalex.org/F4320337367","funder_display_name":"Division of Materials Research"},{"id":"https://openalex.org/G467313275","display_name":null,"funder_award_id":"UL1 TR 002240","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G6349178624","display_name":"High Throughput GO Chip isolation of Lung CTCs for Molecular Diagnosis and Drug Testing","funder_award_id":"5r33ca202867-02","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7775713230","display_name":null,"funder_award_id":"0320740","funder_id":"https://openalex.org/F4320337367","funder_display_name":"Division of Materials Research"},{"id":"https://openalex.org/G8747722198","display_name":"Acquisition of a Focused Ion Beam Workstation for Multidisciplinary Materials Research","funder_award_id":"0320740","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G9000013477","display_name":null,"funder_award_id":"UL1 TR002240","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000895534","display_name":"Michigan Institute for Clinical and Health Research (MICHR)","funder_award_id":"UM1TR004404","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320309652","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291"},{"id":"https://openalex.org/F4320316438","display_name":"Georgia Clinical and Translational Science Alliance","ror":"https://ror.org/034hw7m59"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337367","display_name":"Division of Materials Research","ror":"https://ror.org/01pc7k308"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4224313809.pdf","grobid_xml":"https://content.openalex.org/works/W4224313809.grobid-xml"},"referenced_works_count":54,"referenced_works":["https://openalex.org/W199647299","https://openalex.org/W1492450878","https://openalex.org/W1558034062","https://openalex.org/W1792626808","https://openalex.org/W1872563153","https://openalex.org/W1964184380","https://openalex.org/W1986688132","https://openalex.org/W1991981189","https://openalex.org/W1993913242","https://openalex.org/W1995097523","https://openalex.org/W2012091269","https://openalex.org/W2032084331","https://openalex.org/W2046975261","https://openalex.org/W2050547995","https://openalex.org/W2051274778","https://openalex.org/W2080310376","https://openalex.org/W2088221380","https://openalex.org/W2107277218","https://openalex.org/W2113914943","https://openalex.org/W2114570899","https://openalex.org/W2116388783","https://openalex.org/W2117368354","https://openalex.org/W2119764457","https://openalex.org/W2131548365","https://openalex.org/W2143490853","https://openalex.org/W2151171671","https://openalex.org/W2153768374","https://openalex.org/W2161021183","https://openalex.org/W2169632044","https://openalex.org/W2171947218","https://openalex.org/W2220243639","https://openalex.org/W2254404245","https://openalex.org/W2414585623","https://openalex.org/W2588901189","https://openalex.org/W2735114871","https://openalex.org/W2742066653","https://openalex.org/W2792183232","https://openalex.org/W2793516777","https://openalex.org/W2800968972","https://openalex.org/W2804811661","https://openalex.org/W2806713886","https://openalex.org/W2889646458","https://openalex.org/W2916157147","https://openalex.org/W2945153242","https://openalex.org/W2952683378","https://openalex.org/W2965873243","https://openalex.org/W2967613984","https://openalex.org/W2978481495","https://openalex.org/W3004472410","https://openalex.org/W3011828892","https://openalex.org/W3080249817","https://openalex.org/W3134253202","https://openalex.org/W3169510834","https://openalex.org/W4243370327"],"related_works":["https://openalex.org/W1851952311","https://openalex.org/W3087237025","https://openalex.org/W4205796194","https://openalex.org/W2598440651","https://openalex.org/W2990878540","https://openalex.org/W2945013480","https://openalex.org/W3036038058","https://openalex.org/W1754920572","https://openalex.org/W2884237486","https://openalex.org/W2996450400"],"abstract_inverted_index":{"Melanoma":[0],"is":[1,23,39,92],"one":[2],"of":[3,21,31,78,106,129,196],"the":[4,17,32,82,95,102,154,164,177,189],"most":[5],"aggressive":[6],"skin":[7],"cancers":[8],"due":[9],"to":[10,13,136,149,179],"its":[11],"potential":[12],"metastasize":[14],"widely":[15],"in":[16,47,101,153,198,200],"body.":[18],"The":[19,160,185],"risk":[20],"metastasis":[22],"increased":[24,29],"with":[25,88],"later":[26],"detection":[27],"and":[28,57,65,104,109,145,188],"thickness":[30],"primary":[33,79],"lesion,":[34],"thus":[35],"early":[36],"identification/surgical":[37],"removal":[38],"critical":[40],"for":[41,54,169],"higher":[42],"survival":[43],"rates.":[44],"Recent":[45],"advances":[46],"liquid":[48],"biopsy":[49],"have":[50,70,125],"proposed":[51],"less\u2010invasive":[52],"alternatives":[53],"cancer":[55],"diagnosis":[56],"monitoring":[58],"using":[59,173],"minimal":[60],"invasion":[61],"at":[62,121],"sample":[63],"collection,":[64],"circulating":[66],"tumor":[67],"cells":[68],"(CTCs)":[69],"been":[71],"considered":[72],"a":[73,126,150],"promising":[74],"blood\u2010based":[75],"surrogate":[76],"marker":[77],"tumors.":[80],"Herein,":[81],"melanoma\u2010specific":[83],"OncoBean":[84],"platform":[85],"(MelanoBean)":[86],"conjugated":[87],"melanoma":[89,116,199],"specific":[90],"antibodies":[91],"used.":[93],"From":[94],"comprehensive":[96,190],"studies":[97],"based":[98],"on":[99],"change":[100],"number":[103,128,156],"characteristics":[105],"CTCs/CTCs\u2010clusters":[107],"pre\u2010":[108],"post\u2010surgical":[110],"treatment,":[111],"this":[112],"work":[113],"demonstrates":[114],"that":[115],"patients":[117],"(n":[118,139],"=":[119,140,143],"45)":[120],"all":[122],"stages":[123],"(I\u2013IV)":[124],"noticeable":[127],"CTCs":[130,161,197],"as":[131,133],"well":[132],"CTC\u2010clusters":[134],"compared":[135],"healthy":[137],"donors":[138],"9)":[141],"(p":[142,157],"0.0011),":[144],"surgical":[146],"treatment":[147],"leads":[148],"significant":[151],"decrease":[152],"CTC":[155],"<":[158],"0.0001).":[159],"recovered":[162],"from":[163],"device":[165],"undergo":[166],"molecular":[167,181],"profiling":[168],"melanoma\u2010associated":[170],"genes":[171],"expression":[172],"multiplexed":[174],"qRT\u2010PCR,":[175],"demonstrating":[176],"ability":[178],"monitor":[180],"signature":[182],"through":[183],"treatment.":[184],"presented":[186],"MelanoBean":[187],"approach":[191],"will":[192],"empower":[193],"prognostic":[194],"value":[195],"much":[201],"larger":[202],"cohort":[203],"studies.":[204]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}