{"id":"https://openalex.org/W4224246779","doi":"https://doi.org/10.1186/s12967-022-03384-w","title":"The \u201cGreat Debate\u201d at Immunotherapy Bridge 2021, December 1st\u20132nd, 2021","display_name":"The \u201cGreat Debate\u201d at Immunotherapy Bridge 2021, December 1st\u20132nd, 2021","publication_year":2022,"publication_date":"2022-04-21","ids":{"openalex":"https://openalex.org/W4224246779","doi":"https://doi.org/10.1186/s12967-022-03384-w","pmid":"https://pubmed.ncbi.nlm.nih.gov/35449104","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9022317"},"language":"en","primary_location":{"id":"doi:10.1186/s12967-022-03384-w","doi":"https://doi.org/10.1186/s12967-022-03384-w","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12967-022-03384-w","pdf_url":"https://translational-medicine.biomedcentral.com/track/pdf/10.1186/s12967-022-03384-w","source":{"id":"https://openalex.org/S142026636","display_name":"Journal of Translational Medicine","issn_l":"1479-5876","issn":["1479-5876"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-2","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Translational Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://translational-medicine.biomedcentral.com/track/pdf/10.1186/s12967-022-03384-w","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5029398339","display_name":"Paolo A. Ascierto","orcid":"https://orcid.org/0000-0002-8322-475X","observed_orcids":["https://orcid.org/0000-0002-8322-475X"]},"institutions":[{"id":"https://openalex.org/I4210141868","display_name":"Istituto Nazionale Tumori IRCCS \"Fondazione G. Pascale\"","ror":"https://ror.org/0506y2b23","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210141868","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Paolo A. Ascierto","raw_affiliation_strings":["Department of Melanoma, Cancer Immunotherapy and Innovative Therapy, Istituto Nazionale Tumori IRCCS \"Fondazione G. Pascale\", Naples, Italy. paolo.ascierto@gmail.com","Department of Melanoma, Cancer Immunotherapy and Innovative Therapy, Istituto Nazionale Tumori IRCCS \u201cFondazione G. Pascale\u201d, Naples, Italy"],"raw_orcid":"https://orcid.org/0000-0002-8322-475X","affiliations":[{"raw_affiliation_string":"Department of Melanoma, Cancer Immunotherapy and Innovative Therapy, Istituto Nazionale Tumori IRCCS \"Fondazione G. Pascale\", Naples, Italy. paolo.ascierto@gmail.com","institution_ids":["https://openalex.org/I4210141868"]},{"raw_affiliation_string":"Department of Melanoma, Cancer Immunotherapy and Innovative Therapy, Istituto Nazionale Tumori IRCCS \u201cFondazione G. Pascale\u201d, Naples, Italy","institution_ids":["https://openalex.org/I4210141868"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026029856","display_name":"Lisa Helene Butterfield","orcid":"https://orcid.org/0000-0002-3439-9844","observed_orcids":["https://orcid.org/0000-0002-3439-9844"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]},{"id":"https://openalex.org/I4210109986","display_name":"Parker Institute for Cancer Immunotherapy","ror":"https://ror.org/0184qbg02","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210109986"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lisa H. Butterfield","raw_affiliation_strings":["Microbiology and Immunology, Parker Institute for Cancer Immunotherapy, University of California, San Francisco, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microbiology and Immunology, Parker Institute for Cancer Immunotherapy, University of California, San Francisco, CA, USA","institution_ids":["https://openalex.org/I180670191","https://openalex.org/I4210109986"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024170610","display_name":"Olivera J. Finn","orcid":"https://orcid.org/0000-0003-0930-920X","observed_orcids":["https://orcid.org/0000-0003-0930-920X"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Olivera J. Finn","raw_affiliation_strings":["Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067102201","display_name":"P. Andrew Futreal","orcid":"https://orcid.org/0000-0001-8663-2671","observed_orcids":["https://orcid.org/0000-0001-8663-2671"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew Futreal","raw_affiliation_strings":["Division of Cancer Medicine, Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cancer Medicine, Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028592995","display_name":"Omid Hamid","orcid":"https://orcid.org/0000-0002-8238-4655","observed_orcids":["https://orcid.org/0000-0002-8238-4655"]},"institutions":[{"id":"https://openalex.org/I4210104507","display_name":"Angeles Clinic and Research Institute","ror":"https://ror.org/01ct2ab72","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282927834","https://openalex.org/I4210104507"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Omid Hamid","raw_affiliation_strings":["Medical Oncology, The Angeles Clinic and Research Institute, A Cedar-Sinai Affiliate, Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Oncology, The Angeles Clinic and Research Institute, A Cedar-Sinai Affiliate, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I4210104507"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066301151","display_name":"Theresa M. LaVallee","orcid":"https://orcid.org/0000-0002-1769-3195","observed_orcids":["https://orcid.org/0000-0002-1769-3195"]},"institutions":[{"id":"https://openalex.org/I4210109986","display_name":"Parker Institute for Cancer Immunotherapy","ror":"https://ror.org/0184qbg02","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210109986"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Theresa LaVallee","raw_affiliation_strings":["Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA","institution_ids":["https://openalex.org/I4210109986"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011325668","display_name":"Michael Andrew Postow","orcid":"https://orcid.org/0000-0002-3367-7961","observed_orcids":["https://orcid.org/0000-0002-3367-7961"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael A. Postow","raw_affiliation_strings":["Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY, USA","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049243227","display_name":"Igor J. Puzanov","orcid":"https://orcid.org/0000-0002-9803-3497","observed_orcids":["https://orcid.org/0000-0002-9803-3497"]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Igor Puzanov","raw_affiliation_strings":["Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA","institution_ids":["https://openalex.org/I1292894508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075566772","display_name":"Jeffrey Alan Sosman","orcid":"https://orcid.org/0000-0002-0650-9698","observed_orcids":["https://orcid.org/0000-0002-0650-9698"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey Sosman","raw_affiliation_strings":["Division of Hematology/Oncology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology/Oncology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067266240","display_name":"Bernard A. Fox","orcid":"https://orcid.org/0000-0002-4452-5947","observed_orcids":["https://orcid.org/0000-0002-4452-5947"]},"institutions":[{"id":"https://openalex.org/I2801670537","display_name":"Providence Portland Medical Center","ror":"https://ror.org/015tmw922","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801670537","https://openalex.org/I4210160466","https://openalex.org/I94396219"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bernard A. Fox","raw_affiliation_strings":["Earle A. Chiles Research Institute, Robert W. Franz Cancer Research Center, Providence Cancer Institute, Portland, OR, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Earle A. Chiles Research Institute, Robert W. Franz Cancer Research Center, Providence Cancer Institute, Portland, OR, USA","institution_ids":["https://openalex.org/I2801670537"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033798832","display_name":"Patrick Hwu","orcid":"https://orcid.org/0000-0002-8293-1313","observed_orcids":["https://orcid.org/0000-0002-8293-1313","https://orcid.org/0000-0003-0554-2856"]},"institutions":[{"id":"https://openalex.org/I3019308854","display_name":"Moffitt Cancer Center","ror":"https://ror.org/01xf75524","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019308854"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Patrick Hwu","raw_affiliation_strings":["Moffitt Cancer Center, Tampa, FL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Moffitt Cancer Center, Tampa, FL, USA","institution_ids":["https://openalex.org/I3019308854"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5029398339"],"corresponding_institution_ids":["https://openalex.org/I4210141868"],"apc_list":{"value":3190,"currency":"USD","value_usd":3190},"apc_paid":{"value":3190,"currency":"USD","value_usd":3190},"fwci":0.2073,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.45556706,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"20","issue":"1","first_page":"179","last_page":"179"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.006500000134110451,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/immunotherapy","display_name":"immunotherapy","score":0.8650000095367432},{"id":"https://openalex.org/keywords/oncolytic-viruses","display_name":"oncolytic viruses","score":0.9779999852180481},{"id":"https://openalex.org/keywords/intralesional-therapy","display_name":"intralesional therapy","score":0.9399999976158142},{"id":"https://openalex.org/keywords/immunomodulators","display_name":"immunomodulators","score":0.8399999737739563},{"id":"https://openalex.org/keywords/surrogate-endpoints","display_name":"surrogate endpoints","score":0.9380000233650208},{"id":"https://openalex.org/keywords/progression-free-survival","display_name":"progression-free survival","score":0.7900000214576721},{"id":"https://openalex.org/keywords/response-rate","display_name":"response rate","score":0.8730000257492065},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.949999988079071},{"id":"https://openalex.org/keywords/cancer-vaccines","display_name":"cancer vaccines","score":0.8870000243186951},{"id":"https://openalex.org/keywords/cold-to-hot-tumor-conversion","display_name":"cold-to-hot tumor conversion","score":0.7329999804496765},{"id":"https://openalex.org/keywords/immune-profiling","display_name":"immune profiling","score":0.6330000162124634},{"id":"https://openalex.org/keywords/cancer-immunotherapy","display_name":"cancer immunotherapy","score":0.8259999752044678}],"concepts":[{"id":"https://openalex.org/C82210918","wikidata":"https://www.wikidata.org/wiki/Q1560099","display_name":"Oncolytic virus","level":3,"score":0.793668270111084},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.6070288419723511},{"id":"https://openalex.org/C100776233","wikidata":"https://www.wikidata.org/wiki/Q2532492","display_name":"Bridge (graph theory)","level":2,"score":0.5339431166648865},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5281999707221985},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.43420660495758057},{"id":"https://openalex.org/C527412718","wikidata":"https://www.wikidata.org/wiki/Q855395","display_name":"Interpretation (philosophy)","level":2,"score":0.43142229318618774},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3271365761756897},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2908514142036438},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.23834186792373657},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2281889021396637},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.17951735854148865},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000077982","descriptor_name":"Progression-Free Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007155","descriptor_name":"Immunologic Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007167","descriptor_name":"Immunotherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008495","descriptor_name":"Medical Oncology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008545","descriptor_name":"Melanoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1186/s12967-022-03384-w","doi":"https://doi.org/10.1186/s12967-022-03384-w","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12967-022-03384-w","pdf_url":"https://translational-medicine.biomedcentral.com/track/pdf/10.1186/s12967-022-03384-w","source":{"id":"https://openalex.org/S142026636","display_name":"Journal of Translational Medicine","issn_l":"1479-5876","issn":["1479-5876"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-2","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Translational Medicine","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9022317","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9022317","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Transl Med","raw_type":"Text"},{"id":"pmid:35449104","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35449104","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of translational medicine","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:b62868dd06ff48669cf032113f06cffc","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/b62868dd06ff48669cf032113f06cffc","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-13 (2022)","raw_type":"article"},{"id":"pmh:oai:escholarship.org:ark:/13030/qt0ng3h6t3","doi":null,"is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/0ng3h6t3","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Translational Medicine, vol 20, iss 1","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12967-022-03384-w","doi":"https://doi.org/10.1186/s12967-022-03384-w","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12967-022-03384-w","pdf_url":"https://translational-medicine.biomedcentral.com/track/pdf/10.1186/s12967-022-03384-w","source":{"id":"https://openalex.org/S142026636","display_name":"Journal of Translational Medicine","issn_l":"1479-5876","issn":["1479-5876"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-2","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Translational Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G8527595922","display_name":"Immunoprevention and immunosurveillance of human non-viral cancers","funder_award_id":"R35CA210039","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000856728","display_name":"Cancer Center Support Grant","funder_award_id":"P30CA008748","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4224246779.pdf","grobid_xml":"https://content.openalex.org/works/W4224246779.grobid-xml"},"referenced_works_count":36,"referenced_works":["https://openalex.org/W2009423208","https://openalex.org/W2072843564","https://openalex.org/W2205469793","https://openalex.org/W2296049142","https://openalex.org/W2527833995","https://openalex.org/W2724264513","https://openalex.org/W2756035269","https://openalex.org/W2763265527","https://openalex.org/W2888546921","https://openalex.org/W2897815318","https://openalex.org/W2903247206","https://openalex.org/W2904803926","https://openalex.org/W2915177933","https://openalex.org/W2942554478","https://openalex.org/W2948155539","https://openalex.org/W3012223268","https://openalex.org/W3023939023","https://openalex.org/W3030418407","https://openalex.org/W3046115489","https://openalex.org/W3084135554","https://openalex.org/W3092332802","https://openalex.org/W3104839688","https://openalex.org/W3105662747","https://openalex.org/W3134949487","https://openalex.org/W3163284774","https://openalex.org/W3171912160","https://openalex.org/W3186872020","https://openalex.org/W3202997693","https://openalex.org/W3211961015","https://openalex.org/W3212139125","https://openalex.org/W3213977202","https://openalex.org/W3214227225","https://openalex.org/W3214475605","https://openalex.org/W3217126890","https://openalex.org/W4200017545","https://openalex.org/W4226229241"],"related_works":["https://openalex.org/W3140894956","https://openalex.org/W4366769401","https://openalex.org/W3080152226","https://openalex.org/W2969180340","https://openalex.org/W3165836611","https://openalex.org/W2917381440","https://openalex.org/W3118976690","https://openalex.org/W2318622231","https://openalex.org/W2402226790","https://openalex.org/W3210054708"],"abstract_inverted_index":{"As":[0,99],"part":[1],"of":[2,143,151],"the":[3,13,44,108,115,127,152],"2021":[4],"Immunotherapy":[5],"Bridge":[6,102],"virtual":[7],"congress":[8],"(December":[9],"1-2,":[10],"Naples,":[11],"Italy),":[12],"Great":[14],"Debate":[15],"sessions":[16],"featured":[17],"experts":[18],"who":[19],"were":[20,43,97,105],"assigned":[21],"counter":[22],"opposing":[23],"views":[24,128],"on":[25,135],"four":[26],"important":[27],"questions":[28],"in":[29,130],"immunotherapy":[30],"today.":[31],"The":[32,51],"first":[33],"topic":[34],"was":[35,53,70,81],"whether":[36,54,73],"oncolytic":[37],"viruses":[38],"or":[39,62],"other":[40],"specific":[41],"immunomodulators":[42],"more":[45],"promising":[46],"approach":[47],"for":[48],"intralesional":[49],"therapy.":[50],"second":[52],"early":[55],"surrogate":[56],"endpoints,":[57],"such":[58],"as":[59],"response":[60],"rate":[61],"progression-free":[63],"survival,":[64],"correlate":[65],"with":[66,100],"long-term":[67],"overall":[68],"survival":[69],"considered.":[71],"Thirdly,":[72],"vaccines":[74],"can":[75],"transform":[76],"cold":[77],"into":[78,94],"hot":[79],"tumors":[80],"discussed":[82],"and,":[83],"finally,":[84],"broad":[85],"versus":[86],"deep":[87],"analytic":[88],"profiling":[89],"approaches":[90],"to":[91],"gain":[92],"insights":[93],"immune-oncology":[95],"development":[96],"compared.":[98],"previous":[101],"congresses,":[103],"presenters":[104],"invited":[106],"by":[107],"meeting":[109],"Chairs":[110],"and":[111,148],"positions":[112],"taken":[113],"during":[114],"debates":[116],"may":[117,139],"not":[118],"have":[119],"reflected":[120],"their":[121],"respective":[122],"personal":[123,141],"view.":[124],"In":[125],"addition,":[126],"summarised":[129],"this":[131],"article":[132],"are":[133],"based":[134],"available":[136],"evidence":[137],"but":[138],"reflect":[140],"interpretation":[142],"these":[144],"data,":[145],"clinical":[146],"experience":[147],"subjective":[149],"opinion":[150],"speaker.":[153]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2022-04-26T00:00:00"}