{"id":"https://openalex.org/W4223510063","doi":"https://doi.org/10.1007/s10439-022-02944-x","title":"Effects of MitraClip Therapy on Mitral Flow Patterns and Vortex Formation: An In Vitro Study","display_name":"Effects of MitraClip Therapy on Mitral Flow Patterns and Vortex Formation: An In Vitro Study","publication_year":2022,"publication_date":"2022-04-11","ids":{"openalex":"https://openalex.org/W4223510063","doi":"https://doi.org/10.1007/s10439-022-02944-x","pmid":"https://pubmed.ncbi.nlm.nih.gov/35411431","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11070279"},"language":"en","primary_location":{"id":"doi:10.1007/s10439-022-02944-x","doi":"https://doi.org/10.1007/s10439-022-02944-x","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10439-022-02944-x","pdf_url":null,"source":{"id":"https://openalex.org/S141152059","display_name":"Annals of Biomedical Engineering","issn_l":"0090-6964","issn":["0090-6964","0191-5649","1573-9686"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Biomedical Engineering","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11070279","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035900436","display_name":"Shelley Chee-Mei Gooden","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130701444","display_name":"Georgia Institute of Technology","ror":"https://ror.org/01zkghx44","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shelley Chee-Mei Gooden","raw_affiliation_strings":["Department of Biomedical Engineering, Georgia Institute of Technology, 387 Technology Circle, Atlanta, GA, 30313, USA","Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Georgia Institute of Technology, 387 Technology Circle, Atlanta, GA, 30313, USA","institution_ids":["https://openalex.org/I130701444"]},{"raw_affiliation_string":"Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, USA","institution_ids":["https://openalex.org/I130701444"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072243191","display_name":"Hoda Hatoum","orcid":"https://orcid.org/0000-0001-5538-8960","observed_orcids":["https://orcid.org/0000-0001-5538-8960"]},"institutions":[{"id":"https://openalex.org/I11957088","display_name":"Michigan Technological University","ror":"https://ror.org/0036rpn28","country_code":"US","type":"education","lineage":["https://openalex.org/I11957088"]},{"id":"https://openalex.org/I130701444","display_name":"Georgia Institute of Technology","ror":"https://ror.org/01zkghx44","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hoda Hatoum","raw_affiliation_strings":["Department of Biomedical Engineering, Georgia Institute of Technology, 387 Technology Circle, Atlanta, GA, 30313, USA","Department of Biomedical Engineering, Michigan Technological University, Houghton, MI, USA","Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, USA","Department of Biomedical Engineering, Michigan Technological University, Houghton, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Georgia Institute of Technology, 387 Technology Circle, Atlanta, GA, 30313, USA","institution_ids":["https://openalex.org/I130701444"]},{"raw_affiliation_string":"Department of Biomedical Engineering, Michigan Technological University, Houghton, MI, USA","institution_ids":["https://openalex.org/I11957088"]},{"raw_affiliation_string":"Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, USA","institution_ids":["https://openalex.org/I130701444"]},{"raw_affiliation_string":"Department of Biomedical Engineering, Michigan Technological University, Houghton, USA","institution_ids":["https://openalex.org/I11957088"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086734765","display_name":"Konstantinos Dean Boudoulas","orcid":"https://orcid.org/0000-0003-0625-8750","observed_orcids":["https://orcid.org/0000-0003-0625-8750"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Konstantinos Dean Boudoulas","raw_affiliation_strings":["Division of Cardiovascular Medicine, The Ohio State University, Columbus, OH, USA","Division of Cardiovascular Medicine, The Ohio State University, Columbus, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiovascular Medicine, The Ohio State University, Columbus, OH, USA","institution_ids":["https://openalex.org/I52357470"]},{"raw_affiliation_string":"Division of Cardiovascular Medicine, The Ohio State University, Columbus, USA","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005257616","display_name":"Mani A. Vannan","orcid":"https://orcid.org/0000-0002-4027-5573","observed_orcids":["https://orcid.org/0000-0002-4027-5573"]},"institutions":[{"id":"https://openalex.org/I2801405887","display_name":"Piedmont Atlanta Hospital","ror":"https://ror.org/0008s4w86","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801405887","https://openalex.org/I4210153954"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mani A. Vannan","raw_affiliation_strings":["Marcus Heart Valve Center, Piedmont Heart Institute, Atlanta, GA, USA","Marcus Heart Valve Center, Piedmont Heart Institute, Atlanta, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Marcus Heart Valve Center, Piedmont Heart Institute, Atlanta, GA, USA","institution_ids":["https://openalex.org/I2801405887"]},{"raw_affiliation_string":"Marcus Heart Valve Center, Piedmont Heart Institute, Atlanta, USA","institution_ids":["https://openalex.org/I2801405887"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5013397653","display_name":"Lakshmi Prasad Dasi","orcid":"https://orcid.org/0000-0003-3776-0073","observed_orcids":["https://orcid.org/0000-0003-3776-0073"]},"institutions":[{"id":"https://openalex.org/I130701444","display_name":"Georgia Institute of Technology","ror":"https://ror.org/01zkghx44","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Lakshmi P. Dasi","raw_affiliation_strings":["Department of Biomedical Engineering, Georgia Institute of Technology, 387 Technology Circle, Atlanta, GA, 30313, USA. lakshmi.dasi@gatech.edu","Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Georgia Institute of Technology, 387 Technology Circle, Atlanta, GA, 30313, USA. lakshmi.dasi@gatech.edu","institution_ids":["https://openalex.org/I130701444"]},{"raw_affiliation_string":"Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, USA","institution_ids":["https://openalex.org/I130701444"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5013397653"],"corresponding_institution_ids":["https://openalex.org/I130701444"],"apc_list":{"value":3860,"currency":"USD","value_usd":3860},"apc_paid":null,"fwci":1.0439,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.76830097,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"50","issue":"6","first_page":"680","last_page":"690"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10172","display_name":"Cardiac Valve Diseases and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10172","display_name":"Cardiac Valve Diseases and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10618","display_name":"Aortic Disease and Treatment Approaches","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mitraclip","display_name":"MitraClip","score":0.9990000128746033},{"id":"https://openalex.org/keywords/transcatheter-edge-to-edge-repair","display_name":"transcatheter edge-to-edge repair","score":0.9190000295639038},{"id":"https://openalex.org/keywords/mitral-regurgitation","display_name":"mitral regurgitation","score":0.9980000257492065},{"id":"https://openalex.org/keywords/vortex-formation","display_name":"vortex formation","score":0.9110000133514404},{"id":"https://openalex.org/keywords/reynolds-shear-stress","display_name":"Reynolds shear stress","score":0.9729999899864197},{"id":"https://openalex.org/keywords/vorticity","display_name":"vorticity","score":0.9240000247955322},{"id":"https://openalex.org/keywords/shear-layer","display_name":"shear layer","score":0.5799999833106995},{"id":"https://openalex.org/keywords/recirculation","display_name":"recirculation","score":0.722000002861023},{"id":"https://openalex.org/keywords/jet-flow","display_name":"jet flow","score":0.4000000059604645},{"id":"https://openalex.org/keywords/chaotic-flow","display_name":"chaotic flow","score":0.6570000052452087},{"id":"https://openalex.org/keywords/porcine-mitral-valve","display_name":"porcine mitral valve","score":0.8619999885559082},{"id":"https://openalex.org/keywords/left-heart-simulator","display_name":"left heart simulator","score":0.8809999823570251}],"concepts":[{"id":"https://openalex.org/C2780793704","wikidata":"https://www.wikidata.org/wiki/Q17148524","display_name":"MitraClip","level":3,"score":0.9581199884414673},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5944308042526245},{"id":"https://openalex.org/C2993373945","wikidata":"https://www.wikidata.org/wiki/Q268292","display_name":"Mitral regurgitation","level":2,"score":0.5838685035705566},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4852040112018585},{"id":"https://openalex.org/C57900726","wikidata":"https://www.wikidata.org/wiki/Q492905","display_name":"Diastole","level":3,"score":0.44745463132858276},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4367656111717224},{"id":"https://openalex.org/C207857233","wikidata":"https://www.wikidata.org/wiki/Q1756248","display_name":"Particle image velocimetry","level":3,"score":0.4144143760204315},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.4129263758659363},{"id":"https://openalex.org/C200114574","wikidata":"https://www.wikidata.org/wiki/Q1143513","display_name":"Vorticity","level":3,"score":0.4120280146598816},{"id":"https://openalex.org/C57879066","wikidata":"https://www.wikidata.org/wiki/Q41217","display_name":"Mechanics","level":1,"score":0.3578760623931885},{"id":"https://openalex.org/C140820882","wikidata":"https://www.wikidata.org/wiki/Q732722","display_name":"Vortex","level":2,"score":0.3077644407749176},{"id":"https://openalex.org/C196558001","wikidata":"https://www.wikidata.org/wiki/Q190132","display_name":"Turbulence","level":2,"score":0.08702433109283447},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008943","descriptor_name":"Mitral Valve","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D008944","descriptor_name":"Mitral Valve Insufficiency","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019918","descriptor_name":"Heart Valve Prosthesis Implantation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1007/s10439-022-02944-x","doi":"https://doi.org/10.1007/s10439-022-02944-x","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10439-022-02944-x","pdf_url":null,"source":{"id":"https://openalex.org/S141152059","display_name":"Annals of Biomedical Engineering","issn_l":"0090-6964","issn":["0090-6964","0191-5649","1573-9686"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Biomedical Engineering","raw_type":"journal-article"},{"id":"pmid:35411431","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35411431","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of biomedical engineering","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11070279","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11070279","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Ann Biomed Eng","raw_type":"Text"},{"id":"pmh:oai:digitalcommons.mtu.edu:michigantech-p-35250","doi":null,"is_oa":false,"landing_page_url":"https://digitalcommons.mtu.edu/michigantech-p/15948","pdf_url":null,"source":{"id":"https://openalex.org/S4377196391","display_name":"Digital Commons - Michigan Tech (Michigan Technological University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I11957088","host_organization_name":"Michigan Technological University","host_organization_lineage":["https://openalex.org/I11957088"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Michigan Tech Publications, Part 1","raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:11070279","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11070279","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Ann Biomed Eng","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9074000120162964,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3431449615","display_name":"Superhydrophobic leaflets with vortex generators to reduce turbulence in prosthetic heart valves","funder_award_id":"19POST34380804","funder_id":"https://openalex.org/F4320306230","funder_display_name":"American Heart Association"},{"id":"https://openalex.org/G5908108524","display_name":"Hyaluronan enhanced polymeric heart valve prosthesis","funder_award_id":"R01HL119824","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320306230","display_name":"American Heart Association","ror":"https://ror.org/013kjyp64"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":46,"referenced_works":["https://openalex.org/W130873851","https://openalex.org/W181218134","https://openalex.org/W1548710542","https://openalex.org/W1948467570","https://openalex.org/W1958621425","https://openalex.org/W1972050350","https://openalex.org/W1984426476","https://openalex.org/W1988935719","https://openalex.org/W1989052069","https://openalex.org/W1989375725","https://openalex.org/W1990160050","https://openalex.org/W2035987382","https://openalex.org/W2044639306","https://openalex.org/W2050467051","https://openalex.org/W2066168972","https://openalex.org/W2067775475","https://openalex.org/W2068850287","https://openalex.org/W2078789543","https://openalex.org/W2087689261","https://openalex.org/W2109364789","https://openalex.org/W2124723327","https://openalex.org/W2150418418","https://openalex.org/W2153554615","https://openalex.org/W2155516175","https://openalex.org/W2242315485","https://openalex.org/W2340699717","https://openalex.org/W2396319370","https://openalex.org/W2580792129","https://openalex.org/W2589546873","https://openalex.org/W2599825012","https://openalex.org/W2614788422","https://openalex.org/W2770464886","https://openalex.org/W2791453970","https://openalex.org/W2806750332","https://openalex.org/W2844610275","https://openalex.org/W2887237694","https://openalex.org/W2913551142","https://openalex.org/W2953964989","https://openalex.org/W2961519708","https://openalex.org/W2984428369","https://openalex.org/W2990839718","https://openalex.org/W2998894576","https://openalex.org/W3022689357","https://openalex.org/W3032759674","https://openalex.org/W3109581708","https://openalex.org/W3131470691"],"related_works":["https://openalex.org/W6945123155","https://openalex.org/W4410089347","https://openalex.org/W4406958606","https://openalex.org/W7011695200","https://openalex.org/W7025373293","https://openalex.org/W2340447031","https://openalex.org/W193763978","https://openalex.org/W2883820147","https://openalex.org/W3022689357","https://openalex.org/W2887237694"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2022-04-15T00:00:00"}
