{"id":"https://openalex.org/W4223491166","doi":"https://doi.org/10.1038/s41556-022-00884-1","title":"CellComm infers cellular crosstalk that drives haematopoietic stem and progenitor cell development","display_name":"CellComm infers cellular crosstalk that drives haematopoietic stem and progenitor cell development","publication_year":2022,"publication_date":"2022-04-01","ids":{"openalex":"https://openalex.org/W4223491166","doi":"https://doi.org/10.1038/s41556-022-00884-1","pmid":"https://pubmed.ncbi.nlm.nih.gov/35414020","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10123873"},"language":"en","primary_location":{"id":"doi:10.1038/s41556-022-00884-1","doi":"https://doi.org/10.1038/s41556-022-00884-1","is_oa":false,"landing_page_url":"https://doi.org/10.1038/s41556-022-00884-1","pdf_url":null,"source":{"id":"https://openalex.org/S151741590","display_name":"Nature Cell Biology","issn_l":"1465-7392","issn":["1465-7392","1476-4679"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Cell Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10123873/pdf/nihms-1885485.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078791544","display_name":"Edroaldo Lummertz da Rocha","orcid":"https://orcid.org/0000-0003-0537-4223","observed_orcids":["https://orcid.org/0000-0003-0537-4223"]},"institutions":[{"id":"https://openalex.org/I4104125","display_name":"Universidade Federal de Santa Catarina","ror":"https://ror.org/041akq887","country_code":"BR","type":"education","lineage":["https://openalex.org/I4104125"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Edroaldo Lummertz da Rocha","raw_affiliation_strings":["Department of Microbiology, Immunology and Parasitology, Federal University of Santa Catarina, Florian\u00f3polis, Brazil"],"raw_orcid":"https://orcid.org/0000-0003-0537-4223","affiliations":[{"raw_affiliation_string":"Department of Microbiology, Immunology and Parasitology, Federal University of Santa Catarina, Florian\u00f3polis, Brazil","institution_ids":["https://openalex.org/I4104125"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059814241","display_name":"Caroline Kubaczka","orcid":"https://orcid.org/0000-0002-7783-6602","observed_orcids":["https://orcid.org/0000-0002-7783-6602"]},"institutions":[{"id":"https://openalex.org/I1288882113","display_name":"Boston Children's Hospital","ror":"https://ror.org/00dvg7y05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Caroline Kubaczka","raw_affiliation_strings":["Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA","Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA, USA","Stem Cell Program, Boston Children's Hospital, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0002-7783-6602","affiliations":[{"raw_affiliation_string":"Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA, USA","institution_ids":["https://openalex.org/I1288882113","https://openalex.org/I4210117453"]},{"raw_affiliation_string":"Stem Cell Program, Boston Children's Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I1288882113"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085074935","display_name":"Wade W. Sugden","orcid":"https://orcid.org/0000-0002-8907-7359","observed_orcids":["https://orcid.org/0000-0002-8907-7359"]},"institutions":[{"id":"https://openalex.org/I1288882113","display_name":"Boston Children's Hospital","ror":"https://ror.org/00dvg7y05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wade W. Sugden","raw_affiliation_strings":["Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA, USA","Stem Cell Program, Boston Children's Hospital, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0002-8907-7359","affiliations":[{"raw_affiliation_string":"Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA, USA","institution_ids":["https://openalex.org/I1288882113","https://openalex.org/I4210117453"]},{"raw_affiliation_string":"Stem Cell Program, Boston Children's Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I1288882113"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069227715","display_name":"Mohamad Ali Toufic Najia","orcid":"https://orcid.org/0000-0002-2558-8846","observed_orcids":["https://orcid.org/0000-0002-2558-8846"]},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I1288882113","display_name":"Boston Children's Hospital","ror":"https://ror.org/00dvg7y05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mohamad Ali Najia","raw_affiliation_strings":["Broad Institute of MIT and Harvard, Cambridge, MA, USA","Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA","Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA, USA","Harvard-MIT Health Sciences & Technology, Massachusetts Institute of Technology, Cambridge, MA, USA","Stem Cell Program, Boston Children's Hospital, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0002-2558-8846","affiliations":[{"raw_affiliation_string":"Broad Institute of MIT and Harvard, Cambridge, MA, USA","institution_ids":["https://openalex.org/I107606265"]},{"raw_affiliation_string":"Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA, USA","institution_ids":["https://openalex.org/I1288882113","https://openalex.org/I4210117453"]},{"raw_affiliation_string":"Harvard-MIT Health Sciences & Technology, Massachusetts Institute of Technology, Cambridge, MA, USA","institution_ids":["https://openalex.org/I63966007"]},{"raw_affiliation_string":"Stem Cell Program, Boston Children's Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I1288882113"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084181043","display_name":"Ran Jing","orcid":"https://orcid.org/0000-0002-9248-6524","observed_orcids":["https://orcid.org/0000-0002-9248-6524"]},"institutions":[{"id":"https://openalex.org/I1288882113","display_name":"Boston Children's Hospital","ror":"https://ror.org/00dvg7y05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ran Jing","raw_affiliation_strings":["Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA","Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA, USA","Stem Cell Program, Boston Children's Hospital, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0002-9248-6524","affiliations":[{"raw_affiliation_string":"Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA, USA","institution_ids":["https://openalex.org/I1288882113","https://openalex.org/I4210117453"]},{"raw_affiliation_string":"Stem Cell Program, Boston Children's Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I1288882113"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062100765","display_name":"Arianna Markel","orcid":"https://orcid.org/0000-0001-6550-6983","observed_orcids":["https://orcid.org/0000-0001-6550-6983"]},"institutions":[{"id":"https://openalex.org/I1288882113","display_name":"Boston Children's Hospital","ror":"https://ror.org/00dvg7y05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Arianna Markel","raw_affiliation_strings":["Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA","Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA, USA","Stem Cell Program, Boston Children's Hospital, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA, USA","institution_ids":["https://openalex.org/I1288882113","https://openalex.org/I4210117453"]},{"raw_affiliation_string":"Stem Cell Program, Boston Children's Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I1288882113"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057340059","display_name":"Zachary C. LeBlanc","orcid":"https://orcid.org/0000-0002-1662-2846","observed_orcids":["https://orcid.org/0000-0002-1662-2846"]},"institutions":[{"id":"https://openalex.org/I1288882113","display_name":"Boston Children's Hospital","ror":"https://ror.org/00dvg7y05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zachary C. LeBlanc","raw_affiliation_strings":["Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA, USA","Stem Cell Program, Boston Children's Hospital, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0002-1662-2846","affiliations":[{"raw_affiliation_string":"Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA, USA","institution_ids":["https://openalex.org/I1288882113","https://openalex.org/I4210117453"]},{"raw_affiliation_string":"Stem Cell Program, Boston Children's Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I1288882113"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052725063","display_name":"Rafael dos Santos Peixoto","orcid":"https://orcid.org/0000-0002-7184-2868","observed_orcids":["https://orcid.org/0000-0002-7184-2868"]},"institutions":[{"id":"https://openalex.org/I4104125","display_name":"Universidade Federal de Santa Catarina","ror":"https://ror.org/041akq887","country_code":"BR","type":"education","lineage":["https://openalex.org/I4104125"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Rafael dos Santos Peixoto","raw_affiliation_strings":["Undergraduate program in Automation and Control Engineering, Federal University of Santa Catarina, Florian\u00f3polis, Brazil"],"raw_orcid":"https://orcid.org/0000-0002-7184-2868","affiliations":[{"raw_affiliation_string":"Undergraduate program in Automation and Control Engineering, Federal University of Santa Catarina, Florian\u00f3polis, Brazil","institution_ids":["https://openalex.org/I4104125"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019375725","display_name":"Marcelo Falchetti","orcid":"https://orcid.org/0000-0002-9438-680X","observed_orcids":["https://orcid.org/0000-0002-9438-680X"]},"institutions":[{"id":"https://openalex.org/I4104125","display_name":"Universidade Federal de Santa Catarina","ror":"https://ror.org/041akq887","country_code":"BR","type":"education","lineage":["https://openalex.org/I4104125"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Marcelo Falchetti","raw_affiliation_strings":["Graduate Program of Pharmacology, Center for Biological Sciences, Federal University of Santa Catarina, Florian\u00f3polis, Brazil"],"raw_orcid":"https://orcid.org/0000-0002-9438-680X","affiliations":[{"raw_affiliation_string":"Graduate Program of Pharmacology, Center for Biological Sciences, Federal University of Santa Catarina, Florian\u00f3polis, Brazil","institution_ids":["https://openalex.org/I4104125"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065209470","display_name":"James J. Collins","orcid":"https://orcid.org/0000-0002-5560-8246","observed_orcids":["https://orcid.org/0000-0002-5560-8246"]},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I44142251","display_name":"Wyss Institute for Biologically Inspired Engineering","ror":"https://ror.org/008cfmj78","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I44142251"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James J. Collins","raw_affiliation_strings":["Broad Institute of MIT and Harvard, Cambridge, MA, USA","Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA","Harvard-MIT Health Sciences & Technology, Massachusetts Institute of Technology, Cambridge, MA, USA","Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA","Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, MA, USA","Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0002-5560-8246","affiliations":[{"raw_affiliation_string":"Broad Institute of MIT and Harvard, Cambridge, MA, USA","institution_ids":["https://openalex.org/I107606265"]},{"raw_affiliation_string":"Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA","institution_ids":["https://openalex.org/I63966007"]},{"raw_affiliation_string":"Harvard-MIT Health Sciences & Technology, Massachusetts Institute of Technology, Cambridge, MA, USA","institution_ids":["https://openalex.org/I63966007"]},{"raw_affiliation_string":"Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA","institution_ids":["https://openalex.org/I63966007"]},{"raw_affiliation_string":"Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, MA, USA","institution_ids":["https://openalex.org/I63966007"]},{"raw_affiliation_string":"Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I44142251"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041250508","display_name":"Trista E. North","orcid":"https://orcid.org/0000-0003-1249-563X","observed_orcids":["https://orcid.org/0000-0003-1249-563X"]},"institutions":[{"id":"https://openalex.org/I1288882113","display_name":"Boston Children's Hospital","ror":"https://ror.org/00dvg7y05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210166317","display_name":"Dana-Farber/Boston Children's Cancer and Blood Disorders Center","ror":"https://ror.org/05k11pb55","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113","https://openalex.org/I4210117453","https://openalex.org/I4210166317"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Trista E. North","raw_affiliation_strings":["Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA, USA. trista.north@childrens.harvard.edu","Stem Cell Program, Boston Children's Hospital, Boston, MA, USA. trista.north@childrens.harvard.edu","Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA, USA. trista.north@childrens.harvard.edu","institution_ids":["https://openalex.org/I1288882113","https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210166317"]},{"raw_affiliation_string":"Stem Cell Program, Boston Children's Hospital, Boston, MA, USA. trista.north@childrens.harvard.edu","institution_ids":["https://openalex.org/I1288882113","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA, USA","institution_ids":["https://openalex.org/I1288882113","https://openalex.org/I4210117453"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059348374","display_name":"George Q. Daley","orcid":"https://orcid.org/0000-0002-6346-5919","observed_orcids":["https://orcid.org/0000-0002-6346-5919"]},"institutions":[{"id":"https://openalex.org/I1288882113","display_name":"Boston Children's Hospital","ror":"https://ror.org/00dvg7y05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210166317","display_name":"Dana-Farber/Boston Children's Cancer and Blood Disorders Center","ror":"https://ror.org/05k11pb55","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113","https://openalex.org/I4210117453","https://openalex.org/I4210166317"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"George Q. Daley","raw_affiliation_strings":["Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA. George.Daley@childrens.harvard.edu","Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA, USA. George.Daley@childrens.harvard.edu","Stem Cell Program, Boston Children's Hospital, Boston, MA, USA. George.Daley@childrens.harvard.edu","Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0002-6346-5919","affiliations":[{"raw_affiliation_string":"Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA. George.Daley@childrens.harvard.edu","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA, USA. George.Daley@childrens.harvard.edu","institution_ids":["https://openalex.org/I1288882113","https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210166317"]},{"raw_affiliation_string":"Stem Cell Program, Boston Children's Hospital, Boston, MA, USA. George.Daley@childrens.harvard.edu","institution_ids":["https://openalex.org/I1288882113","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA, USA","institution_ids":["https://openalex.org/I1288882113","https://openalex.org/I4210117453"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5041250508","https://openalex.org/A5059348374"],"corresponding_institution_ids":["https://openalex.org/I1288882113","https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210166317"],"apc_list":{"value":11390,"currency":"USD","value_usd":11390},"apc_paid":null,"fwci":3.764,"has_fulltext":true,"cited_by_count":29,"citation_normalized_percentile":{"value":0.94571686,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"24","issue":"4","first_page":"579","last_page":"589"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.7567999958992004,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.7567999958992004,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.07980000227689743,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.042899999767541885,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intercellular-communication","display_name":"intercellular communication","score":0.878000020980835},{"id":"https://openalex.org/keywords/hematopoietic-stem-and-progenitor-cells","display_name":"hematopoietic stem and progenitor cells","score":0.9309999942779541},{"id":"https://openalex.org/keywords/transcriptional-regulatory-networks","display_name":"transcriptional regulatory networks","score":0.8920000195503235},{"id":"https://openalex.org/keywords/stat3","display_name":"STAT3","score":0.9810000061988831},{"id":"https://openalex.org/keywords/nr0b2","display_name":"NR0B2","score":0.9890000224113464},{"id":"https://openalex.org/keywords/yb-1","display_name":"YB-1","score":0.9980000257492065},{"id":"https://openalex.org/keywords/app","display_name":"APP","score":0.9620000123977661},{"id":"https://openalex.org/keywords/zebrafish","display_name":"zebrafish","score":0.7170000076293945},{"id":"https://openalex.org/keywords/mice","display_name":"mice","score":0.7919999957084656},{"id":"https://openalex.org/keywords/human","display_name":"human","score":0.8669999837875366}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7861989736557007},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.7182689905166626},{"id":"https://openalex.org/C2776878037","wikidata":"https://www.wikidata.org/wiki/Q169444","display_name":"Zebrafish","level":3,"score":0.6930131912231445},{"id":"https://openalex.org/C169822122","wikidata":"https://www.wikidata.org/wiki/Q230187","display_name":"Crosstalk","level":2,"score":0.6921440958976746},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.6418743133544922},{"id":"https://openalex.org/C109159458","wikidata":"https://www.wikidata.org/wiki/Q919283","display_name":"Haematopoiesis","level":3,"score":0.6240284442901611},{"id":"https://openalex.org/C201750760","wikidata":"https://www.wikidata.org/wiki/Q1896218","display_name":"Progenitor cell","level":3,"score":0.6162605881690979},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.5226311683654785},{"id":"https://openalex.org/C148738053","wikidata":"https://www.wikidata.org/wiki/Q210861","display_name":"Cellular differentiation","level":3,"score":0.46708011627197266},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.14983302354812622},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09075948596000671},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006410","descriptor_name":"Hematopoiesis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006412","descriptor_name":"Hematopoietic Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008650","descriptor_name":"Mesonephros","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015027","descriptor_name":"Zebrafish","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1038/s41556-022-00884-1","doi":"https://doi.org/10.1038/s41556-022-00884-1","is_oa":false,"landing_page_url":"https://doi.org/10.1038/s41556-022-00884-1","pdf_url":null,"source":{"id":"https://openalex.org/S151741590","display_name":"Nature Cell Biology","issn_l":"1465-7392","issn":["1465-7392","1476-4679"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Cell Biology","raw_type":"journal-article"},{"id":"pmid:35414020","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35414020","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature cell biology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10123873","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10123873","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10123873/pdf/nihms-1885485.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Nat Cell Biol","raw_type":"Text"},{"id":"pmh:oai:dspace.mit.edu:1721.1/147990","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/1721.1/147990","pdf_url":null,"source":{"id":"https://openalex.org/S4306400425","display_name":"DSpace@MIT (Massachusetts Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I63966007","host_organization_name":"Massachusetts Institute of Technology","host_organization_lineage":["https://openalex.org/I63966007"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Prof. Collins","raw_type":"Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:10123873","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10123873","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10123873/pdf/nihms-1885485.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Nat Cell Biol","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.46810001134872437}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1497438808","display_name":"Molecular Circuits in the Hematopoietic Stem Cell Niche","funder_award_id":"RC2DK120535","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G1809215792","display_name":null,"funder_award_id":"F32 DK122715","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G1990547329","display_name":"Customized stem cells for clinical application in blood disorders","funder_award_id":"R24DK092760","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G225254872","display_name":"Biomechanical Activation of Yap Induces Hematopoietic Stem Cell Production","funder_award_id":"R01HL152636","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G5701583907","display_name":"Mechanisms of Flow-Mediated YAP Activation in Hematopoietic Stem Cells","funder_award_id":"1f32dk122715-01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7110652781","display_name":"Developmental Activation of the Inflammasome Controls Hematopoietic Stem Cell Production","funder_award_id":"R01HL154580","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G7697434441","display_name":"Metabolic regulation of hematopoietic stem cell specification and function","funder_award_id":"R01DK098241","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G8044294020","display_name":"Stem cells for therapeutics discovery in genetic blood disorders","funder_award_id":"U01HL134812","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G9000886041","display_name":"Mechanisms of Flow-driven Transcriptional Control of Hematopoietic Stem Cell Development by YAP","funder_award_id":"K01DK129409","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"},{"id":"https://openalex.org/F4320321091","display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","ror":"https://ror.org/00x0ma614"},{"id":"https://openalex.org/F4320322025","display_name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","ror":"https://ror.org/03swz6y49"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4223491166.pdf","grobid_xml":"https://content.openalex.org/works/W4223491166.grobid-xml"},"referenced_works_count":41,"referenced_works":["https://openalex.org/W1980860344","https://openalex.org/W2000551045","https://openalex.org/W2011687861","https://openalex.org/W2021539006","https://openalex.org/W2025776507","https://openalex.org/W2032911882","https://openalex.org/W2044525257","https://openalex.org/W2050376918","https://openalex.org/W2053831749","https://openalex.org/W2067340489","https://openalex.org/W2076453500","https://openalex.org/W2086335524","https://openalex.org/W2099606984","https://openalex.org/W2100541459","https://openalex.org/W2118995117","https://openalex.org/W2129231504","https://openalex.org/W2148351140","https://openalex.org/W2151804917","https://openalex.org/W2166676212","https://openalex.org/W2259100343","https://openalex.org/W2294537429","https://openalex.org/W2295326929","https://openalex.org/W2396681433","https://openalex.org/W2531797269","https://openalex.org/W2557829103","https://openalex.org/W2735778198","https://openalex.org/W2767647222","https://openalex.org/W2793006183","https://openalex.org/W2809369541","https://openalex.org/W2886366143","https://openalex.org/W2938986126","https://openalex.org/W2948119083","https://openalex.org/W2953998221","https://openalex.org/W3003520855","https://openalex.org/W3012485315","https://openalex.org/W3016834261","https://openalex.org/W3021023222","https://openalex.org/W3033732631","https://openalex.org/W3073328849","https://openalex.org/W3107940478","https://openalex.org/W4223952512"],"related_works":["https://openalex.org/W4223952512","https://openalex.org/W6887898438","https://openalex.org/W4401889175","https://openalex.org/W4226146739","https://openalex.org/W2159241859","https://openalex.org/W2105372361","https://openalex.org/W2371976436","https://openalex.org/W4402024591","https://openalex.org/W2039053938","https://openalex.org/W6980938045"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":9},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2022-04-15T00:00:00"}