{"id":"https://openalex.org/W4220947351","doi":"https://doi.org/10.1055/s-0042-1744144","title":"Post-Transplant Biliary Strictures: An Updated Review","display_name":"Post-Transplant Biliary Strictures: An Updated Review","publication_year":2022,"publication_date":"2022-03-09","ids":{"openalex":"https://openalex.org/W4220947351","doi":"https://doi.org/10.1055/s-0042-1744144","pmid":"https://pubmed.ncbi.nlm.nih.gov/35263796"},"language":"en","primary_location":{"id":"doi:10.1055/s-0042-1744144","doi":"https://doi.org/10.1055/s-0042-1744144","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-0042-1744144","pdf_url":null,"source":{"id":"https://openalex.org/S176130430","display_name":"Seminars in Liver Disease","issn_l":"0272-8087","issn":["0272-8087","1098-8971"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seminars in Liver Disease","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015129584","display_name":"Matthew J. Fasullo","orcid":"https://orcid.org/0000-0003-3787-7626","observed_orcids":["https://orcid.org/0000-0003-3787-7626"]},"institutions":[{"id":"https://openalex.org/I184840846","display_name":"Virginia Commonwealth University","ror":"https://ror.org/02nkdxk79","country_code":"US","type":"education","lineage":["https://openalex.org/I184840846"]},{"id":"https://openalex.org/I72019824","display_name":"Virginia Commonwealth University Medical Center","ror":"https://ror.org/057xmsr27","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I72019824"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Matthew Fasullo","raw_affiliation_strings":["Division of Gastroenterology and Hepatology, Central Virginia Veterans Affairs Medicine Center, Richmond, Virginia","Division of Gastroenterology and Hepatology, Virginia Commonwealth University (VCU) Medical Center, Richmond, Virginia"],"raw_orcid":"https://orcid.org/0000-0003-3787-7626","affiliations":[{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, Central Virginia Veterans Affairs Medicine Center, Richmond, Virginia","institution_ids":[]},{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, Virginia Commonwealth University (VCU) Medical Center, Richmond, Virginia","institution_ids":["https://openalex.org/I184840846","https://openalex.org/I72019824"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071138263","display_name":"Tilak Shah","orcid":"https://orcid.org/0000-0003-4818-2571","observed_orcids":["https://orcid.org/0000-0003-4818-2571"]},"institutions":[{"id":"https://openalex.org/I184840846","display_name":"Virginia Commonwealth University","ror":"https://ror.org/02nkdxk79","country_code":"US","type":"education","lineage":["https://openalex.org/I184840846"]},{"id":"https://openalex.org/I72019824","display_name":"Virginia Commonwealth University Medical Center","ror":"https://ror.org/057xmsr27","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I72019824"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tilak Shah","raw_affiliation_strings":["Division of Gastroenterology and Hepatology, Central Virginia Veterans Affairs Medicine Center, Richmond, Virginia","Division of Gastroenterology and Hepatology, Virginia Commonwealth University (VCU) Medical Center, Richmond, Virginia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, Central Virginia Veterans Affairs Medicine Center, Richmond, Virginia","institution_ids":[]},{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, Virginia Commonwealth University (VCU) Medical Center, Richmond, Virginia","institution_ids":["https://openalex.org/I184840846","https://openalex.org/I72019824"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100849694","display_name":"Huiping Zhou","orcid":"https://orcid.org/0000-0002-0050-372X","observed_orcids":["https://orcid.org/0000-0002-0050-372X"]},"institutions":[{"id":"https://openalex.org/I184840846","display_name":"Virginia Commonwealth University","ror":"https://ror.org/02nkdxk79","country_code":"US","type":"education","lineage":["https://openalex.org/I184840846"]},{"id":"https://openalex.org/I2801770128","display_name":"Hunter Holmes McGuire VA Medical Center","ror":"https://ror.org/04fp78s33","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I2801770128","https://openalex.org/I4210159720"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Huiping Zhou","raw_affiliation_strings":["Department of Microbiology and Immunology, VCU and McGuire Veterans Affairs Medical Center, Richmond, Virginia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, VCU and McGuire Veterans Affairs Medical Center, Richmond, Virginia","institution_ids":["https://openalex.org/I184840846","https://openalex.org/I2801770128"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5004639766","display_name":"Mohammad Shadab Siddiqui","orcid":"https://orcid.org/0000-0001-7392-7489","observed_orcids":["https://orcid.org/0000-0001-7392-7489"]},"institutions":[{"id":"https://openalex.org/I184840846","display_name":"Virginia Commonwealth University","ror":"https://ror.org/02nkdxk79","country_code":"US","type":"education","lineage":["https://openalex.org/I184840846"]},{"id":"https://openalex.org/I72019824","display_name":"Virginia Commonwealth University Medical Center","ror":"https://ror.org/057xmsr27","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I72019824"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mohammad S. Siddiqui","raw_affiliation_strings":["Division of Gastroenterology and Hepatology, Virginia Commonwealth University (VCU) Medical Center, Richmond, Virginia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, Virginia Commonwealth University (VCU) Medical Center, Richmond, Virginia","institution_ids":["https://openalex.org/I184840846","https://openalex.org/I72019824"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5015129584"],"corresponding_institution_ids":["https://openalex.org/I184840846","https://openalex.org/I72019824"],"apc_list":null,"apc_paid":null,"fwci":0.4753,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.4200542,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":97},"biblio":{"volume":"42","issue":"02","first_page":"225","last_page":"232"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10999","display_name":"Organ Transplantation Techniques and Outcomes","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10999","display_name":"Organ Transplantation Techniques and Outcomes","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10518","display_name":"Gallbladder and Bile Duct Disorders","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12460","display_name":"Pediatric Hepatobiliary Diseases and Treatments","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/liver-transplantation","display_name":"liver transplantation","score":0.8970000147819519},{"id":"https://openalex.org/keywords/biliary-complications","display_name":"biliary complications","score":0.9649999737739563},{"id":"https://openalex.org/keywords/anastomotic-stenosis","display_name":"anastomotic stricture","score":0.9800000190734863},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.9570000171661377},{"id":"https://openalex.org/keywords/natural-history-disease","display_name":"natural history (disease)","score":0.8820000290870667},{"id":"https://openalex.org/keywords/diagnostic-testing","display_name":"diagnostic testing","score":0.8970000147819519},{"id":"https://openalex.org/keywords/treatment-strategy","display_name":"treatment options","score":0.9440000057220459},{"id":"https://openalex.org/keywords/retransplantation","display_name":"retransplantation","score":0.7770000100135803},{"id":"https://openalex.org/keywords/end-stage-liver-disease","display_name":"end-stage liver disease","score":0.843999981880188}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9200025796890259},{"id":"https://openalex.org/C2779609443","wikidata":"https://www.wikidata.org/wiki/Q1368191","display_name":"Liver transplantation","level":3,"score":0.8364370465278625},{"id":"https://openalex.org/C163276114","wikidata":"https://www.wikidata.org/wiki/Q484591","display_name":"Natural history","level":2,"score":0.6817877888679504},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.6249281167984009},{"id":"https://openalex.org/C8443397","wikidata":"https://www.wikidata.org/wiki/Q15177","display_name":"Anastomosis","level":2,"score":0.5839996337890625},{"id":"https://openalex.org/C2780603604","wikidata":"https://www.wikidata.org/wiki/Q21281037","display_name":"Biliary disease","level":2,"score":0.5284243226051331},{"id":"https://openalex.org/C179755657","wikidata":"https://www.wikidata.org/wiki/Q58702","display_name":"Mortality rate","level":2,"score":0.4709806442260742},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.44400060176849365},{"id":"https://openalex.org/C2777075537","wikidata":"https://www.wikidata.org/wiki/Q929737","display_name":"Liver disease","level":2,"score":0.44225820899009705},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4254457950592041},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3917865455150604},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3768739402294159},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3588525354862213},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.33384501934051514},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D002779","descriptor_name":"Cholestasis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D002779","descriptor_name":"Cholestasis","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D003251","descriptor_name":"Constriction, Pathologic","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D003251","descriptor_name":"Constriction, Pathologic","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011183","descriptor_name":"Postoperative Complications","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D011183","descriptor_name":"Postoperative Complications","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016031","descriptor_name":"Liver Transplantation","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D058625","descriptor_name":"End Stage Liver Disease","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1055/s-0042-1744144","doi":"https://doi.org/10.1055/s-0042-1744144","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-0042-1744144","pdf_url":null,"source":{"id":"https://openalex.org/S176130430","display_name":"Seminars in Liver Disease","issn_l":"0272-8087","issn":["0272-8087","1098-8971"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seminars in Liver Disease","raw_type":"journal-article"},{"id":"pmid:35263796","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35263796","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seminars in liver disease","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4324902294","display_name":null,"funder_award_id":"IK6BX004477","funder_id":"https://openalex.org/F4320306127","funder_display_name":"U.S. Department of Veterans Affairs"}],"funders":[{"id":"https://openalex.org/F4320306127","display_name":"U.S. Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":71,"referenced_works":["https://openalex.org/W207017637","https://openalex.org/W1500109982","https://openalex.org/W1966620940","https://openalex.org/W1967160640","https://openalex.org/W1968530276","https://openalex.org/W1973315849","https://openalex.org/W1980939815","https://openalex.org/W1981787602","https://openalex.org/W1988191714","https://openalex.org/W1989064821","https://openalex.org/W2000717524","https://openalex.org/W2006640229","https://openalex.org/W2007506124","https://openalex.org/W2010979377","https://openalex.org/W2020731777","https://openalex.org/W2023541738","https://openalex.org/W2026298959","https://openalex.org/W2032804260","https://openalex.org/W2047016760","https://openalex.org/W2055947078","https://openalex.org/W2058497905","https://openalex.org/W2060900599","https://openalex.org/W2062971487","https://openalex.org/W2067292366","https://openalex.org/W2068104237","https://openalex.org/W2076458210","https://openalex.org/W2080503852","https://openalex.org/W2085521665","https://openalex.org/W2088680922","https://openalex.org/W2090821259","https://openalex.org/W2091648746","https://openalex.org/W2091768114","https://openalex.org/W2094393447","https://openalex.org/W2102628919","https://openalex.org/W2135463077","https://openalex.org/W2138556865","https://openalex.org/W2141624426","https://openalex.org/W2149337928","https://openalex.org/W2150698118","https://openalex.org/W2153167978","https://openalex.org/W2165334685","https://openalex.org/W2168644992","https://openalex.org/W2171146419","https://openalex.org/W2182740715","https://openalex.org/W2286550614","https://openalex.org/W2413256535","https://openalex.org/W2470737046","https://openalex.org/W2514460475","https://openalex.org/W2542346551","https://openalex.org/W2550723245","https://openalex.org/W2594493728","https://openalex.org/W2602733729","https://openalex.org/W2743012035","https://openalex.org/W2765747410","https://openalex.org/W2776608283","https://openalex.org/W2876076122","https://openalex.org/W2898065424","https://openalex.org/W2901284463","https://openalex.org/W2903449430","https://openalex.org/W2911509193","https://openalex.org/W2970869880","https://openalex.org/W2980628864","https://openalex.org/W3009733757","https://openalex.org/W3083477002","https://openalex.org/W3093650635","https://openalex.org/W3114315794","https://openalex.org/W3124078024","https://openalex.org/W3156241284","https://openalex.org/W3182466807","https://openalex.org/W4240847566","https://openalex.org/W4300107636"],"related_works":["https://openalex.org/W4280572681","https://openalex.org/W4392556091","https://openalex.org/W2059920337","https://openalex.org/W2413158757","https://openalex.org/W1998939464","https://openalex.org/W4409360342","https://openalex.org/W1529713541","https://openalex.org/W4402894213","https://openalex.org/W7099451705","https://openalex.org/W1499431857"],"abstract_inverted_index":{"Liver":[0],"transplantation":[1],"(LT)":[2],"is":[3,79],"the":[4],"only":[5],"curative":[6],"therapy":[7],"in":[8],"patients":[9],"with":[10,14,33,43,61],"end-stage":[11],"liver":[12],"disease":[13],"excellent":[15],"long-term":[16],"survival;":[17],"however,":[18],"LT":[19],"recipients":[20],"are":[21,30,53],"at":[22],"risk":[23,102],"of":[24,76,101],"significant":[25,44],"complications.":[26],"Among":[27],"these":[28,56],"complications":[29,32,57],"biliary":[31,114],"an":[34],"incidence":[35],"ranging":[36],"from":[37],"5":[38],"to":[39,65,71,96],"32%":[40],"and":[41,47,51,67,90,104,109],"associated":[42,60],"post-LT":[45,113],"morbidity":[46],"mortality.":[48],"Prompt":[49],"recognition":[50],"management":[52],"critical":[54],"as":[55],"have":[58],"been":[59],"mortality":[62],"rates":[63,69],"up":[64,70],"19%":[66],"retransplantation":[68],"13%.":[72],"An":[73],"important":[74],"limitation":[75],"published":[77],"studies":[78],"that":[80],"a":[81],"large":[82],"proportion":[83],"does":[84],"not":[85],"discriminate":[86],"between":[87],"anastomotic":[88],"strictures":[89],"nonanastomotic":[91],"strictures.":[92,115],"This":[93],"review":[94],"aims":[95],"summarize":[97],"our":[98],"current":[99],"understanding":[100],"factors":[103],"natural":[105],"history,":[106],"diagnostic":[107],"testing,":[108],"treatment":[110],"options":[111],"for":[112]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2022-04-03T00:00:00"}