{"id":"https://openalex.org/W4220737494","doi":"https://doi.org/10.1080/15548627.2022.2038999","title":"Lamp1 mediates lipid transport, but is dispensable for autophagy in Drosophila","display_name":"Lamp1 mediates lipid transport, but is dispensable for autophagy in Drosophila","publication_year":2022,"publication_date":"2022-03-10","ids":{"openalex":"https://openalex.org/W4220737494","doi":"https://doi.org/10.1080/15548627.2022.2038999","pmid":"https://pubmed.ncbi.nlm.nih.gov/35266854","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9542896"},"language":"en","primary_location":{"id":"doi:10.1080/15548627.2022.2038999","doi":"https://doi.org/10.1080/15548627.2022.2038999","is_oa":true,"landing_page_url":"https://doi.org/10.1080/15548627.2022.2038999","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1080/15548627.2022.2038999?needAccess=true","source":{"id":"https://openalex.org/S102544370","display_name":"Autophagy","issn_l":"1554-8627","issn":["1554-8627","1554-8635"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Autophagy","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.tandfonline.com/doi/pdf/10.1080/15548627.2022.2038999?needAccess=true","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058704660","display_name":"Norin Yasin Chaudhry","orcid":"https://orcid.org/0000-0002-8815-472X","observed_orcids":["https://orcid.org/0000-0002-8815-472X"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Norin Chaudhry","raw_affiliation_strings":["Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA, USA"],"raw_orcid":"https://orcid.org/0000-0002-8815-472X","affiliations":[{"raw_affiliation_string":"Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA, USA","institution_ids":["https://openalex.org/I173911158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006672394","display_name":"Margaux Sica","orcid":"https://orcid.org/0000-0002-8421-9792","observed_orcids":["https://orcid.org/0000-0002-8421-9792"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Margaux Sica","raw_affiliation_strings":["Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, USA"],"raw_orcid":"https://orcid.org/0000-0002-8421-9792","affiliations":[{"raw_affiliation_string":"Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, USA","institution_ids":["https://openalex.org/I129975664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056558578","display_name":"Satya Surabhi","orcid":"https://orcid.org/0000-0002-1888-249X","observed_orcids":["https://orcid.org/0000-0002-1888-249X"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Satya Surabhi","raw_affiliation_strings":["Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, USA"],"raw_orcid":"https://orcid.org/0000-0002-1888-249X","affiliations":[{"raw_affiliation_string":"Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, USA","institution_ids":["https://openalex.org/I129975664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087167518","display_name":"David S\u00e1nchez Hern\u00e1ndez","orcid":"https://orcid.org/0000-0002-3883-8170","observed_orcids":["https://orcid.org/0000-0002-3883-8170"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David Sanchez Hernandez","raw_affiliation_strings":["Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, USA"],"raw_orcid":"https://orcid.org/0000-0002-3883-8170","affiliations":[{"raw_affiliation_string":"Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, USA","institution_ids":["https://openalex.org/I129975664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101730238","display_name":"Ana Mesquita","orcid":"https://orcid.org/0000-0002-0560-1601","observed_orcids":["https://orcid.org/0000-0002-0560-1601"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ana Mesquita","raw_affiliation_strings":["Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, USA"],"raw_orcid":"https://orcid.org/0000-0002-0560-1601","affiliations":[{"raw_affiliation_string":"Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, USA","institution_ids":["https://openalex.org/I129975664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008991085","display_name":"Adem Selimovic","orcid":"https://orcid.org/0000-0003-0334-2033","observed_orcids":["https://orcid.org/0000-0003-0334-2033"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Adem Selimovic","raw_affiliation_strings":["Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA, USA"],"raw_orcid":"https://orcid.org/0000-0003-0334-2033","affiliations":[{"raw_affiliation_string":"Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA, USA","institution_ids":["https://openalex.org/I173911158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014925070","display_name":"Ayesha Riaz","orcid":"https://orcid.org/0000-0002-4627-4133","observed_orcids":["https://orcid.org/0000-0002-4627-4133"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ayesha Riaz","raw_affiliation_strings":["Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA, USA"],"raw_orcid":"https://orcid.org/0000-0002-4627-4133","affiliations":[{"raw_affiliation_string":"Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA, USA","institution_ids":["https://openalex.org/I173911158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045330380","display_name":"Laury Lescat","orcid":"https://orcid.org/0000-0003-4882-8520","observed_orcids":["https://orcid.org/0000-0003-4882-8520"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laury Lescat","raw_affiliation_strings":["Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, USA"],"raw_orcid":"https://orcid.org/0000-0003-4882-8520","affiliations":[{"raw_affiliation_string":"Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, USA","institution_ids":["https://openalex.org/I129975664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087680483","display_name":"Hua Bai","orcid":"https://orcid.org/0000-0003-2221-7545","observed_orcids":["https://orcid.org/0000-0003-2221-7545","https://orcid.org/0000-0002-5436-1245"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hua Bai","raw_affiliation_strings":["Department of Genetics, Development and Cell Biology, Iowa State University, Ames, IA, USA"],"raw_orcid":"https://orcid.org/0000-0003-2221-7545","affiliations":[{"raw_affiliation_string":"Department of Genetics, Development and Cell Biology, Iowa State University, Ames, IA, USA","institution_ids":["https://openalex.org/I173911158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050316598","display_name":"Gustavo C. MacIntosh","orcid":"https://orcid.org/0000-0003-1350-1229","observed_orcids":["https://orcid.org/0000-0003-1350-1229"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Gustavo C. MacIntosh","raw_affiliation_strings":["Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA, USA"],"raw_orcid":"https://orcid.org/0000-0003-1350-1229","affiliations":[{"raw_affiliation_string":"Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA, USA","institution_ids":["https://openalex.org/I173911158"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015710789","display_name":"Andreas Jenny","orcid":"https://orcid.org/0000-0001-5989-8212","observed_orcids":["https://orcid.org/0000-0001-5989-8212"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Andreas Jenny","raw_affiliation_strings":["Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, USA","Department of Genetics, Albert Einstein College of Medicine New York, NY, USA"],"raw_orcid":"https://orcid.org/0000-0001-5989-8212","affiliations":[{"raw_affiliation_string":"Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, USA","institution_ids":["https://openalex.org/I129975664"]},{"raw_affiliation_string":"Department of Genetics, Albert Einstein College of Medicine New York, NY, USA","institution_ids":["https://openalex.org/I129975664"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5015710789","https://openalex.org/A5050316598"],"corresponding_institution_ids":["https://openalex.org/I129975664","https://openalex.org/I173911158"],"apc_list":null,"apc_paid":null,"fwci":4.1709,"has_fulltext":true,"cited_by_count":55,"citation_normalized_percentile":{"value":0.96059113,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"18","issue":"10","first_page":"2443","last_page":"2458"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10587","display_name":"Autophagy in Disease and Therapy","score":0.8393999934196472,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10587","display_name":"Autophagy in Disease and Therapy","score":0.8393999934196472,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.1289999932050705,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":0.019600000232458115,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lamp1","display_name":"LAMP1","score":0.7850000262260437},{"id":"https://openalex.org/keywords/lamp2","display_name":"LAMP2","score":0.9480000138282776},{"id":"https://openalex.org/keywords/lysosomal-associated-membrane-protein","display_name":"lysosomal-associated membrane protein","score":0.9380000233650208},{"id":"https://openalex.org/keywords/lipid-transport","display_name":"lipid transport","score":0.9700000286102295},{"id":"https://openalex.org/keywords/diacylglycerol","display_name":"diacylglycerol","score":0.8309999704360962},{"id":"https://openalex.org/keywords/sterols","display_name":"sterols","score":0.8740000128746033},{"id":"https://openalex.org/keywords/endolysosomal-system","display_name":"endolysosomal system","score":0.7770000100135803},{"id":"https://openalex.org/keywords/drosophila","display_name":"Drosophila","score":0.7319999933242798},{"id":"https://openalex.org/keywords/lipid-metabolism","display_name":"lipid metabolism","score":0.4959999918937683},{"id":"https://openalex.org/keywords/lysosomal-dysfunction","display_name":"lysosomal dysfunction","score":0.531000018119812},{"id":"https://openalex.org/keywords/autophagolysosomes","display_name":"autophagolysosomes","score":0.6259999871253967},{"id":"https://openalex.org/keywords/escrt","display_name":"ESCRT","score":0.8360000252723694},{"id":"https://openalex.org/keywords/chaperone-mediated-autophagy","display_name":"chaperone-mediated autophagy","score":0.8080000281333923}],"concepts":[{"id":"https://openalex.org/C2777135640","wikidata":"https://www.wikidata.org/wiki/Q18028463","display_name":"LAMP1","level":4,"score":0.8923240900039673},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.798123836517334},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.7688899636268616},{"id":"https://openalex.org/C203522944","wikidata":"https://www.wikidata.org/wiki/Q288322","display_name":"Autophagy","level":3,"score":0.7236654758453369},{"id":"https://openalex.org/C2780216420","wikidata":"https://www.wikidata.org/wiki/Q83330","display_name":"Lysosome","level":3,"score":0.5661394000053406},{"id":"https://openalex.org/C102747710","wikidata":"https://www.wikidata.org/wiki/Q824237","display_name":"Endosome","level":3,"score":0.5151447057723999},{"id":"https://openalex.org/C2781452922","wikidata":"https://www.wikidata.org/wiki/Q2892805","display_name":"Proteostasis","level":2,"score":0.41666916012763977},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.27410009503364563},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.07606694102287292},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.0},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000596","descriptor_name":"Amino Acids","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001343","descriptor_name":"Autophagy","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001672","descriptor_name":"Biocompatible Materials","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001672","descriptor_name":"Biocompatible Materials","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004075","descriptor_name":"Diglycerides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004075","descriptor_name":"Diglycerides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005033","descriptor_name":"Ethylmaleimide","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005033","descriptor_name":"Ethylmaleimide","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D005347","descriptor_name":"Fibroblasts","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008075","descriptor_name":"Lipoproteins, HDL","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008075","descriptor_name":"Lipoproteins, HDL","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D008077","descriptor_name":"Lipoproteins, LDL","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008247","descriptor_name":"Lysosomes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008322","descriptor_name":"Mammals","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011505","descriptor_name":"Protein-Tyrosine Kinases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013261","descriptor_name":"Sterols","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013261","descriptor_name":"Sterols","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D014280","descriptor_name":"Triglycerides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014404","descriptor_name":"Tubulin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017228","descriptor_name":"Hepatocyte Growth Factor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020123","descriptor_name":"Sirolimus","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D020506","descriptor_name":"Untranslated Regions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D029721","descriptor_name":"Drosophila Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D037281","descriptor_name":"Calnexin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D050600","descriptor_name":"SNARE Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051907","descriptor_name":"Lysosomal Membrane Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051907","descriptor_name":"Lysosomal Membrane Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D052118","descriptor_name":"Lysosomal-Associated Membrane Protein 1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056827","descriptor_name":"Endosomal Sorting Complexes Required for Transport","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1080/15548627.2022.2038999","doi":"https://doi.org/10.1080/15548627.2022.2038999","is_oa":true,"landing_page_url":"https://doi.org/10.1080/15548627.2022.2038999","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1080/15548627.2022.2038999?needAccess=true","source":{"id":"https://openalex.org/S102544370","display_name":"Autophagy","issn_l":"1554-8627","issn":["1554-8627","1554-8635"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Autophagy","raw_type":"journal-article"},{"id":"doi:10.1101/2021.03.03.432938","doi":"https://doi.org/10.1101/2021.03.03.432938","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2021.03.03.432938","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2021/03/03/2021.03.03.432938.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmh:oai:pubmedcentral.nih.gov:9542896","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9542896","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Autophagy","raw_type":"Text"},{"id":"pmid:35266854","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35266854","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Autophagy","raw_type":"Journal Article"},{"id":"pmh:oai:dr.lib.iastate.edu:20.500.12876/7wbO22Yv","doi":null,"is_oa":false,"landing_page_url":"https://dr.lib.iastate.edu/handle/20.500.12876/7wbO22Yv","pdf_url":null,"source":{"id":"https://openalex.org/S4377196104","display_name":"Iowa State University Digital Repository (Iowa State University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I173911158","host_organization_name":"Iowa State University","host_organization_lineage":["https://openalex.org/I173911158"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"https://doi.org/10.1080/15548627.2022.2038999","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1080/15548627.2022.2038999","doi":"https://doi.org/10.1080/15548627.2022.2038999","is_oa":true,"landing_page_url":"https://doi.org/10.1080/15548627.2022.2038999","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1080/15548627.2022.2038999?needAccess=true","source":{"id":"https://openalex.org/S102544370","display_name":"Autophagy","issn_l":"1554-8627","issn":["1554-8627","1554-8635"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Autophagy","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2202491679","display_name":"Regulation of endosomal Microautophagy by cellular stress.","funder_award_id":"18POST34030231","funder_id":"https://openalex.org/F4320306230","funder_display_name":"American Heart Association"},{"id":"https://openalex.org/G2607579963","display_name":"Autonomous and Non-Autonomous Regulation of Cardiac Aging","funder_award_id":"R01AG058741","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G2944312264","display_name":"Autophagy-dependent and -independent mechanisms of RNA transport to the vacuole and their role in rRNA turnover and cellular homeostasis","funder_award_id":"1714996","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G9000877850","display_name":"Cancer Center Support Grant","funder_award_id":"P30CA013330","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000917750","display_name":"Endosomal Microautophagy in Drosophila","funder_award_id":"R01GM119160","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320306230","display_name":"American Heart Association","ror":"https://ror.org/013kjyp64"},{"id":"https://openalex.org/F4320311090","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4220737494.pdf","grobid_xml":"https://content.openalex.org/works/W4220737494.grobid-xml"},"referenced_works_count":110,"referenced_works":["https://openalex.org/W192235689","https://openalex.org/W1190839962","https://openalex.org/W1507640463","https://openalex.org/W1523693806","https://openalex.org/W1582894915","https://openalex.org/W1643149493","https://openalex.org/W1809721560","https://openalex.org/W1967809393","https://openalex.org/W1968322176","https://openalex.org/W1968733649","https://openalex.org/W1977869829","https://openalex.org/W1979450804","https://openalex.org/W1979871710","https://openalex.org/W1983225557","https://openalex.org/W1995383725","https://openalex.org/W1998356880","https://openalex.org/W2000035899","https://openalex.org/W2000607281","https://openalex.org/W2001197606","https://openalex.org/W2003887174","https://openalex.org/W2004396698","https://openalex.org/W2004496597","https://openalex.org/W2004798786","https://openalex.org/W2005487986","https://openalex.org/W2021919397","https://openalex.org/W2025044590","https://openalex.org/W2030013085","https://openalex.org/W2031565698","https://openalex.org/W2033615443","https://openalex.org/W2038049117","https://openalex.org/W2041687573","https://openalex.org/W2043291430","https://openalex.org/W2046968941","https://openalex.org/W2052578642","https://openalex.org/W2055230639","https://openalex.org/W2060579362","https://openalex.org/W2061773040","https://openalex.org/W2062172017","https://openalex.org/W2083919459","https://openalex.org/W2086871300","https://openalex.org/W2093262727","https://openalex.org/W2093882277","https://openalex.org/W2103818266","https://openalex.org/W2107277218","https://openalex.org/W2107766190","https://openalex.org/W2109716633","https://openalex.org/W2110676385","https://openalex.org/W2114360920","https://openalex.org/W2117695104","https://openalex.org/W2118156930","https://openalex.org/W2118956678","https://openalex.org/W2119421712","https://openalex.org/W2128573075","https://openalex.org/W2132218390","https://openalex.org/W2137015675","https://openalex.org/W2148351021","https://openalex.org/W2148698435","https://openalex.org/W2150737519","https://openalex.org/W2152517932","https://openalex.org/W2157272365","https://openalex.org/W2159042370","https://openalex.org/W2161184130","https://openalex.org/W2161597083","https://openalex.org/W2167279371","https://openalex.org/W2170208222","https://openalex.org/W2181193101","https://openalex.org/W2194304382","https://openalex.org/W2297171960","https://openalex.org/W2300170141","https://openalex.org/W2345256317","https://openalex.org/W2382399754","https://openalex.org/W2416900138","https://openalex.org/W2419471796","https://openalex.org/W2438571291","https://openalex.org/W2478311706","https://openalex.org/W2517263277","https://openalex.org/W2518281858","https://openalex.org/W2523545810","https://openalex.org/W2523686550","https://openalex.org/W2549597224","https://openalex.org/W2581879485","https://openalex.org/W2622548957","https://openalex.org/W2743254891","https://openalex.org/W2752326209","https://openalex.org/W2795906582","https://openalex.org/W2801103925","https://openalex.org/W2882031129","https://openalex.org/W2886388595","https://openalex.org/W2887708784","https://openalex.org/W2891426606","https://openalex.org/W2898204371","https://openalex.org/W2902686872","https://openalex.org/W2905996686","https://openalex.org/W2938574745","https://openalex.org/W2938698371","https://openalex.org/W2943661845","https://openalex.org/W2944828463","https://openalex.org/W2979846121","https://openalex.org/W2988906435","https://openalex.org/W2991456852","https://openalex.org/W3010663034","https://openalex.org/W3013477904","https://openalex.org/W3019973397","https://openalex.org/W3021884249","https://openalex.org/W3023310607","https://openalex.org/W3026538114","https://openalex.org/W3036563505","https://openalex.org/W3039449072","https://openalex.org/W3094705906","https://openalex.org/W4213174091"],"related_works":["https://openalex.org/W4399729744","https://openalex.org/W4411274424","https://openalex.org/W2986112649","https://openalex.org/W2110676385","https://openalex.org/W2038049117","https://openalex.org/W2032062018","https://openalex.org/W7017424826","https://openalex.org/W2300170141","https://openalex.org/W3111637518","https://openalex.org/W4411878643"],"abstract_inverted_index":{"Abstract":[0],"The":[1],"endolysosomal":[2],"system":[3],"not":[4,105],"only":[5],"is":[6,85,104],"an":[7,127,187],"integral":[8],"part":[9],"of":[10,22,37,63,90,129,152,178,194,204],"the":[11,34,64,80,130,160,168,192,201],"cellular":[12],"catabolic":[13],"machinery":[14],"that":[15,79,112,138],"processes":[16],"and":[17,32,41,51,73,94,154,207],"recycles":[18],"nutrients":[19],"for":[20,56,107,165],"synthesis":[21],"biomaterials,":[23],"but":[24],"also":[25],"acts":[26],"as":[27,147],"signaling":[28],"hub":[29],"to":[30,97,190],"sense":[31],"coordinate":[33],"energy":[35],"state":[36],"cells":[38],"with":[39,210],"growth":[40],"differentiation.":[42],"Lysosomal":[43],"dysfunction":[44],"adversely":[45],"influences":[46],"vesicular":[47],"transport-dependent":[48],"macromolecular":[49],"degradation":[50],"thus":[52],"causes":[53],"serious":[54],"problems":[55],"human":[57],"health.":[58],"In":[59],"mammalian":[60],"cells,":[61],"loss":[62],"lysosome":[65],"associated":[66],"membrane":[67],"proteins":[68,196],"LAMP1/2":[69],"strongly":[70],"impacts":[71],"autophagy":[72,113],"cholesterol":[74],"trafficking.":[75],"Here":[76],"we":[77,136],"show":[78,149],"previously":[81],"uncharacterized":[82],"Drosophila":[83,102,186],"Lamp1":[84,103,123,139,179],"a":[86],"bona":[87],"fide":[88],"homolog":[89],"vertebrate":[91],"LAMP1/2.":[92],"Surprisingly":[93],"in":[95,115,126,133,144,171,180,197],"contrast":[96],"Lamp1/2":[98,116],"double":[99],"mutant":[100,140],"mice,":[101],"required":[106],"viability":[108],"or":[109],"autophagy,":[110],"suggesting":[111],"defects":[114,143],"mutants":[117],"may":[118],"have":[119,142],"indirect":[120],"causes.":[121],"However,":[122],"deficiency":[124],"results":[125,174],"expansion":[128],"acidic":[131],"compartment":[132],"flies.":[134],"Furthermore,":[135],"find":[137],"larvae":[141],"lipid":[145,162,181,198],"metabolism":[146],"they":[148],"elevated":[150],"levels":[151],"sterols":[153],"diacylglycerols":[155],"(DAGs).":[156],"Since":[157],"DAGs":[158],"are":[159],"main":[161],"species":[163],"used":[164],"transport":[166],"though":[167],"hemolymph":[169],"(blood)":[170],"insects,":[172],"our":[173],"indicate":[175],"broader":[176],"functions":[177],"transport.":[182],"Our":[183],"findings":[184],"make":[185],"ideal":[188],"model":[189],"study":[191],"role":[193],"LAMP":[195],"assimilation":[199],"without":[200,208],"confounding":[202],"effects":[203],"their":[205],"storage":[206],"interfering":[209],"autophagic":[211],"processes.":[212]},"counts_by_year":[{"year":2026,"cited_by_count":13},{"year":2025,"cited_by_count":21},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":3}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2022-04-03T00:00:00"}