{"id":"https://openalex.org/W4213183116","doi":"https://doi.org/10.1177/11795514221074663","title":"Position of Sulfonylureas in the Current ERA: Review of National and International Guidelines","display_name":"Position of Sulfonylureas in the Current ERA: Review of National and International Guidelines","publication_year":2022,"publication_date":"2022-01-01","ids":{"openalex":"https://openalex.org/W4213183116","doi":"https://doi.org/10.1177/11795514221074663","pmid":"https://pubmed.ncbi.nlm.nih.gov/35185350"},"language":"en","primary_location":{"id":"doi:10.1177/11795514221074663","doi":"https://doi.org/10.1177/11795514221074663","is_oa":true,"landing_page_url":"https://doi.org/10.1177/11795514221074663","pdf_url":null,"source":{"id":"https://openalex.org/S4210222520","display_name":"Clinical Medicine Insights Endocrinology and Diabetes","issn_l":"1178-1173","issn":["1178-1173","1179-5514"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Medicine Insights: Endocrinology and Diabetes","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1177/11795514221074663","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034363861","display_name":"Viswanathan Mohan","orcid":"https://orcid.org/0000-0001-5038-6210","observed_orcids":["https://orcid.org/0000-0001-5038-6210","https://orcid.org/0000-0003-2263-3725"]},"institutions":[{"id":"https://openalex.org/I4210137848","display_name":"Dr. Mohan's Diabetes Specialities Centre","ror":"https://ror.org/02z9d3e27","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210137848"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Viswanathan Mohan","raw_affiliation_strings":["Dr. Mohan\u2019s Diabetes Specialities Centre, Chennai, Tamil Nadu, India","Dr. Mohan's Diabetes Specialities Centre, Chennai, Tamil Nadu, India"],"raw_orcid":"https://orcid.org/0000-0001-5038-6210","affiliations":[{"raw_affiliation_string":"Dr. Mohan\u2019s Diabetes Specialities Centre, Chennai, Tamil Nadu, India","institution_ids":["https://openalex.org/I4210137848"]},{"raw_affiliation_string":"Dr. Mohan's Diabetes Specialities Centre, Chennai, Tamil Nadu, India","institution_ids":["https://openalex.org/I4210137848"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039062359","display_name":"Banshi Saboo","orcid":"https://orcid.org/0000-0001-7293-8864","observed_orcids":["https://orcid.org/0000-0001-7293-8864"]},"institutions":[{"id":"https://openalex.org/I4210131238","display_name":"Diabetes Care & Hormone Clinic","ror":"https://ror.org/02jg1vm67","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210131238"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Banshi Saboo","raw_affiliation_strings":["Diabetes Care and Hormone Clinic, Ahmedabad, Gujarat, India"],"raw_orcid":"https://orcid.org/0000-0001-7293-8864","affiliations":[{"raw_affiliation_string":"Diabetes Care and Hormone Clinic, Ahmedabad, Gujarat, India","institution_ids":["https://openalex.org/I4210131238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020753288","display_name":"Jabbar Khader","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129862065","display_name":"Government Medical College","ror":"https://ror.org/007fenw03","country_code":"IN","type":"education","lineage":["https://openalex.org/I129862065"]},{"id":"https://openalex.org/I4210093352","display_name":"Government Medical College and Hospital","ror":"https://ror.org/00hhrbd92","country_code":"IN","type":"education","lineage":["https://openalex.org/I4210093352"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Jabbar Khader","raw_affiliation_strings":["Department of Endocrinology, Government Medical College, Trivandrum, Kerala, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology, Government Medical College, Trivandrum, Kerala, India","institution_ids":["https://openalex.org/I129862065","https://openalex.org/I4210093352"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113483727","display_name":"Kirtikumar D Modi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802469017","display_name":"CARE Hospitals","ror":"https://ror.org/01vka3a64","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I2802469017"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Kirtikumar D Modi","raw_affiliation_strings":["Care Hospital, Hyderabad, Telangana, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Care Hospital, Hyderabad, Telangana, India","institution_ids":["https://openalex.org/I2802469017"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023953707","display_name":"Sushil Jindal","orcid":"https://orcid.org/0000-0001-8858-0641","observed_orcids":["https://orcid.org/0000-0001-8858-0641"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sushil Jindal","raw_affiliation_strings":["Department of Endocrinology, People\u2019s college of Medical Sciences, Bhopal, Madhya Pradesh, India","Department of Endocrinology, People's college of Medical Sciences, Bhopal, Madhya Pradesh, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology, People\u2019s college of Medical Sciences, Bhopal, Madhya Pradesh, India","institution_ids":[]},{"raw_affiliation_string":"Department of Endocrinology, People's college of Medical Sciences, Bhopal, Madhya Pradesh, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113252593","display_name":"SUBHASH KUMAR WANGNOO","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1302839792","display_name":"Indraprastha Apollo Hospitals","ror":"https://ror.org/013vzz882","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I1302839792"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Subhash Kumar Wangnoo","raw_affiliation_strings":["Endocrinologist and Diabetologist, Apollo centre for Obesity, Diabetes and Endocrinology (ACODE), Indraprastha Apollo Hospital, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Endocrinologist and Diabetologist, Apollo centre for Obesity, Diabetes and Endocrinology (ACODE), Indraprastha Apollo Hospital, New Delhi, India","institution_ids":["https://openalex.org/I1302839792"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5066845026","display_name":"Amarnath Sugumaran","orcid":"https://orcid.org/0000-0001-9207-5605","observed_orcids":["https://orcid.org/0000-0001-9207-5605"]},"institutions":[{"id":"https://openalex.org/I4210138224","display_name":"Sanofi (India)","ror":"https://ror.org/043zsj038","country_code":"IN","type":"company","lineage":["https://openalex.org/I3018075036","https://openalex.org/I4210138224"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Sugumaran Amarnath","raw_affiliation_strings":["Department of Medical affairs, Sanofi India Ltd., Mumbai, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical affairs, Sanofi India Ltd., Mumbai, India","institution_ids":["https://openalex.org/I4210138224"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5034363861"],"corresponding_institution_ids":["https://openalex.org/I4210137848"],"apc_list":{"value":1500,"currency":"USD","value_usd":1500},"apc_paid":{"value":1500,"currency":"USD","value_usd":1500},"fwci":3.3212,"has_fulltext":false,"cited_by_count":25,"citation_normalized_percentile":{"value":0.93253142,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"15","issue":null,"first_page":"11795514221074663","last_page":"11795514221074663"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10401","display_name":"Diabetes Treatment and Management","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10401","display_name":"Diabetes Treatment and Management","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sulfonylureas","display_name":"sulfonylureas","score":1.0},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9940000176429749},{"id":"https://openalex.org/keywords/oral-antidiabetic-drugs","display_name":"oral antidiabetic drugs","score":0.7850000262260437},{"id":"https://openalex.org/keywords/diabetes-care-guidelines","display_name":"diabetes management guidelines","score":0.7120000123977661},{"id":"https://openalex.org/keywords/cardiovascular-safety","display_name":"cardiovascular safety","score":0.8479999899864197},{"id":"https://openalex.org/keywords/second-line-treatment","display_name":"second-line therapy","score":0.7990000247955322},{"id":"https://openalex.org/keywords/metformin-combination-therapy","display_name":"metformin combination therapy","score":0.828000009059906},{"id":"https://openalex.org/keywords/low-and-middle-income-countries","display_name":"low- and middle-income countries","score":0.8730000257492065},{"id":"https://openalex.org/keywords/benefit-cost-ratio","display_name":"benefit-cost ratio","score":0.7889999747276306},{"id":"https://openalex.org/keywords/guideline-recommendations","display_name":"guideline recommendations","score":0.5830000042915344}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7897020578384399},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.6083470582962036},{"id":"https://openalex.org/C2780323712","wikidata":"https://www.wikidata.org/wiki/Q19484","display_name":"Metformin","level":3,"score":0.552070677280426},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5163053870201111},{"id":"https://openalex.org/C3017438360","wikidata":"https://www.wikidata.org/wiki/Q11188","display_name":"Global population","level":3,"score":0.4453420042991638},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.4423516094684601},{"id":"https://openalex.org/C78780964","wikidata":"https://www.wikidata.org/wiki/Q7233193","display_name":"Position paper","level":2,"score":0.4391062557697296},{"id":"https://openalex.org/C2776217022","wikidata":"https://www.wikidata.org/wiki/Q1100933","display_name":"Diabetes management","level":4,"score":0.42863112688064575},{"id":"https://openalex.org/C2910068830","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 Diabetes Mellitus","level":3,"score":0.42557236552238464},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.4005027413368225},{"id":"https://openalex.org/C112930515","wikidata":"https://www.wikidata.org/wiki/Q4389547","display_name":"Risk analysis (engineering)","level":1,"score":0.3972287178039551},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.2252536416053772},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.09825244545936584},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1177/11795514221074663","doi":"https://doi.org/10.1177/11795514221074663","is_oa":true,"landing_page_url":"https://doi.org/10.1177/11795514221074663","pdf_url":null,"source":{"id":"https://openalex.org/S4210222520","display_name":"Clinical Medicine Insights Endocrinology and Diabetes","issn_l":"1178-1173","issn":["1178-1173","1179-5514"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Medicine Insights: Endocrinology and Diabetes","raw_type":"journal-article"},{"id":"pmid:35185350","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35185350","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical medicine insights. Endocrinology and diabetes","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8854230","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8854230","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Clin Med Insights Endocrinol Diabetes","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:81c2e3a1348b42509d7e97585e669239","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/81c2e3a1348b42509d7e97585e669239","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Clinical Medicine Insights: Endocrinology and Diabetes, Vol 15 (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1177/11795514221074663","doi":"https://doi.org/10.1177/11795514221074663","is_oa":true,"landing_page_url":"https://doi.org/10.1177/11795514221074663","pdf_url":null,"source":{"id":"https://openalex.org/S4210222520","display_name":"Clinical Medicine Insights Endocrinology and Diabetes","issn_l":"1178-1173","issn":["1178-1173","1179-5514"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Medicine Insights: Endocrinology and Diabetes","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W1526927233","https://openalex.org/W1871508201","https://openalex.org/W2150959326","https://openalex.org/W2314989814","https://openalex.org/W2461780991","https://openalex.org/W2596827363","https://openalex.org/W2757494156","https://openalex.org/W2798054615","https://openalex.org/W2805520818","https://openalex.org/W2863590425","https://openalex.org/W2894993577","https://openalex.org/W2895674567","https://openalex.org/W2900149048","https://openalex.org/W2907711465","https://openalex.org/W2911557642","https://openalex.org/W2946415573","https://openalex.org/W2952199255","https://openalex.org/W2963811946","https://openalex.org/W2969746584","https://openalex.org/W2970964869","https://openalex.org/W2972210460","https://openalex.org/W2972869264","https://openalex.org/W2974098728","https://openalex.org/W2977158547","https://openalex.org/W3000421244","https://openalex.org/W3004838676","https://openalex.org/W3019401037","https://openalex.org/W3023689184","https://openalex.org/W3031038558","https://openalex.org/W3099504979","https://openalex.org/W4213285299","https://openalex.org/W4236126199","https://openalex.org/W4244971414","https://openalex.org/W4251642701","https://openalex.org/W4254445254"],"related_works":["https://openalex.org/W2520648843","https://openalex.org/W1920632900","https://openalex.org/W2105403615","https://openalex.org/W2904715359","https://openalex.org/W2350706782","https://openalex.org/W4380836775","https://openalex.org/W2529083239","https://openalex.org/W3144179538","https://openalex.org/W4312131330","https://openalex.org/W2126122658"],"abstract_inverted_index":{"Sulfonylureas":[0],"(SUs)":[1],"are":[2],"one":[3],"of":[4,35,40,48,59,64,72,99,108,126,146,157,168,177],"the":[5,33,38,51,57,62,78,89,106,119,124,147,158,166,174],"commonly":[6],"prescribed":[7],"oral":[8],"anti-hyperglycemic":[9],"agents":[10],"(AHA)":[11],"in":[12,19,37,50,61,94,111,134,139,186,197],"low-":[13],"and":[14,53,81,87,102,122,142,161,188],"middle-income":[15],"countries":[16],"(LMICs),":[17],"either":[18],"combination":[20,135],"with":[21,136],"metformin":[22],"therapy":[23,132],"or":[24,133],"alone.":[25],"However,":[26],"concern":[27],"about":[28],"cardiovascular":[29],"safety":[30],"has":[31,66],"limited":[32],"use":[34,125],"SUs":[36,60,93,129,170,189],"management":[39,63,86,107,176],"type":[41],"2":[42],"diabetes":[43,65,85],"mellitus":[44],"(T2DM).":[45],"Additionally,":[46,179],"lack":[47],"uniformity":[49],"national":[52,80,101],"international":[54,82,103],"guidelines":[55,83,104,116],"regarding":[56],"positioning":[58],"also":[67],"been":[68],"reported.":[69],"The":[70],"objective":[71],"this":[73],"review":[74],"was":[75],"to":[76,92,192],"assess":[77],"various":[79,95],"on":[84,105,152],"understand":[88],"recommendations":[90],"specific":[91,143],"scenarios.":[96,144],"A":[97],"total":[98],"33":[100],"T2DM":[109],"published":[110],"English":[112],"were":[113],"evaluated.":[114],"These":[115],"have":[117],"considered":[118],"latest":[120],"evidence":[121],"suggest":[123],"certain":[127],"second-generation":[128],"as":[130],"second-line":[131],"other":[137],"AHAs":[138],"select":[140],"population":[141],"Identification":[145],"appropriate":[148,169],"population,":[149],"classification":[150],"based":[151],"underlying":[153],"risk,":[154],"thorough":[155],"assessment":[156],"comorbid":[159],"conditions,":[160],"a":[162],"step-wise":[163],"approach":[164],"for":[165,173],"selection":[167],"is":[171],"essential":[172],"effective":[175],"T2DM.":[178],"cost-to-benefit":[180],"ratio":[181],"should":[182],"be":[183],"considered,":[184],"particularly":[185],"LMICs,":[187],"could":[190],"continue":[191],"play":[193],"an":[194],"important":[195],"role":[196],"such":[198],"settings.":[199]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":1}],"updated_date":"2026-09-24T07:57:37.273135","created_date":"2025-10-10T00:00:00"}