{"id":"https://openalex.org/W4213025896","doi":"https://doi.org/10.1515/znc-2021-0274","title":"Electrochemical quantification of biomarker myeloperoxidase","display_name":"Electrochemical quantification of biomarker myeloperoxidase","publication_year":2022,"publication_date":"2022-02-22","ids":{"openalex":"https://openalex.org/W4213025896","doi":"https://doi.org/10.1515/znc-2021-0274","pmid":"https://pubmed.ncbi.nlm.nih.gov/35191282"},"language":"en","primary_location":{"id":"doi:10.1515/znc-2021-0274","doi":"https://doi.org/10.1515/znc-2021-0274","is_oa":false,"landing_page_url":"https://doi.org/10.1515/znc-2021-0274","pdf_url":null,"source":{"id":"https://openalex.org/S67401564","display_name":"Zeitschrift f\u00fcr Naturforschung C","issn_l":"0341-0471","issn":["0341-0471","0939-5075","1865-7125"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310313990","host_organization_name":"De Gruyter","host_organization_lineage":["https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zeitschrift f\u00fcr Naturforschung C","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/2117/363520","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061710340","display_name":"Javier Hoyo","orcid":"https://orcid.org/0000-0002-9927-2465","observed_orcids":["https://orcid.org/0000-0002-9927-2465"]},"institutions":[{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]},{"id":"https://openalex.org/I9617848","display_name":"Universitat Polit\u00e8cnica de Catalunya","ror":"https://ror.org/03mb6wj31","country_code":"ES","type":"education","lineage":["https://openalex.org/I9617848"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Javier Hoyo","raw_affiliation_strings":["Department of Chemical Engineering , Grup de Biotecnologia Molecular i Industrial, Universitat Polit\u00e8cnica de Catalunya , Rambla Sant Nebridi 22, 08222 , Terrasa , Spain","Department of Physical-Chemistry , Universitat de Barcelona , 08028 Barcelona , Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering , Grup de Biotecnologia Molecular i Industrial, Universitat Polit\u00e8cnica de Catalunya , Rambla Sant Nebridi 22, 08222 , Terrasa , Spain","institution_ids":["https://openalex.org/I9617848"]},{"raw_affiliation_string":"Department of Physical-Chemistry , Universitat de Barcelona , 08028 Barcelona , Spain","institution_ids":["https://openalex.org/I71999127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034796424","display_name":"Arnau Bassegoda","orcid":"https://orcid.org/0000-0001-6701-2127","observed_orcids":["https://orcid.org/0000-0001-6701-2127"]},"institutions":[{"id":"https://openalex.org/I9617848","display_name":"Universitat Polit\u00e8cnica de Catalunya","ror":"https://ror.org/03mb6wj31","country_code":"ES","type":"education","lineage":["https://openalex.org/I9617848"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Arnau Bassegoda","raw_affiliation_strings":["Department of Chemical Engineering , Grup de Biotecnologia Molecular i Industrial, Universitat Polit\u00e8cnica de Catalunya , Rambla Sant Nebridi 22, 08222 , Terrasa , Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering , Grup de Biotecnologia Molecular i Industrial, Universitat Polit\u00e8cnica de Catalunya , Rambla Sant Nebridi 22, 08222 , Terrasa , Spain","institution_ids":["https://openalex.org/I9617848"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042381306","display_name":"Tzanko Tzanov","orcid":"https://orcid.org/0000-0002-8568-1110","observed_orcids":["https://orcid.org/0000-0002-8568-1110"]},"institutions":[{"id":"https://openalex.org/I9617848","display_name":"Universitat Polit\u00e8cnica de Catalunya","ror":"https://ror.org/03mb6wj31","country_code":"ES","type":"education","lineage":["https://openalex.org/I9617848"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Tzanko Tzanov","raw_affiliation_strings":["Department of Chemical Engineering , Grup de Biotecnologia Molecular i Industrial, Universitat Polit\u00e8cnica de Catalunya , Rambla Sant Nebridi 22, 08222 , Terrasa , Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering , Grup de Biotecnologia Molecular i Industrial, Universitat Polit\u00e8cnica de Catalunya , Rambla Sant Nebridi 22, 08222 , Terrasa , Spain","institution_ids":["https://openalex.org/I9617848"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5042381306"],"corresponding_institution_ids":["https://openalex.org/I9617848"],"apc_list":{"value":2000,"currency":"EUR","value_usd":2107},"apc_paid":null,"fwci":0.4422,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.44314137,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"77","issue":"7-8","first_page":"297","last_page":"302"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10212","display_name":"Electrochemical sensors and biosensors","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10212","display_name":"Electrochemical sensors and biosensors","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11434","display_name":"Electrochemical Analysis and Applications","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/1603","display_name":"Electrochemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/myeloperoxidase","display_name":"myeloperoxidase","score":1.0},{"id":"https://openalex.org/keywords/point-of-care-testing","display_name":"point-of-care testing","score":0.8309999704360962},{"id":"https://openalex.org/keywords/electrochemical-biosensor","display_name":"electrochemical biosensor","score":0.8220000267028809},{"id":"https://openalex.org/keywords/iron-active-sites","display_name":"iron active sites","score":0.4480000138282776},{"id":"https://openalex.org/keywords/wound-infection","display_name":"wound infection","score":0.6110000014305115},{"id":"https://openalex.org/keywords/chronic-obstructive-pulmonary-disease","display_name":"chronic obstructive pulmonary disease","score":0.8960000276565552},{"id":"https://openalex.org/keywords/cardiac-biomarkers","display_name":"cardiac biomarkers","score":0.6610000133514404},{"id":"https://openalex.org/keywords/inflammatory-markers","display_name":"inflammatory markers","score":0.7789999842643738},{"id":"https://openalex.org/keywords/infection-markers","display_name":"infection biomarkers","score":0.8059999942779541}],"concepts":[{"id":"https://openalex.org/C203565725","wikidata":"https://www.wikidata.org/wiki/Q420012","display_name":"Myeloperoxidase","level":3,"score":0.9221839904785156},{"id":"https://openalex.org/C64841741","wikidata":"https://www.wikidata.org/wiki/Q491983","display_name":"Point-of-care testing","level":2,"score":0.7716265916824341},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.6561601161956787},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.45468923449516296},{"id":"https://openalex.org/C52859227","wikidata":"https://www.wikidata.org/wiki/Q7877","display_name":"Electrochemistry","level":3,"score":0.4273460805416107},{"id":"https://openalex.org/C2781031786","wikidata":"https://www.wikidata.org/wiki/Q287582","display_name":"ABTS","level":4,"score":0.42036813497543335},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3724822402000427},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.33668410778045654},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.33175626397132874},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.24913868308067322},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.22439372539520264},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.2140151560306549},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.10605886578559875},{"id":"https://openalex.org/C2781401929","wikidata":"https://www.wikidata.org/wiki/Q5205953","display_name":"DPPH","level":3,"score":0.0},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C17525397","wikidata":"https://www.wikidata.org/wiki/Q176140","display_name":"Electrode","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D004396","descriptor_name":"Coloring Agents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009195","descriptor_name":"Peroxidase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010084","descriptor_name":"Oxidation-Reduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1515/znc-2021-0274","doi":"https://doi.org/10.1515/znc-2021-0274","is_oa":false,"landing_page_url":"https://doi.org/10.1515/znc-2021-0274","pdf_url":null,"source":{"id":"https://openalex.org/S67401564","display_name":"Zeitschrift f\u00fcr Naturforschung C","issn_l":"0341-0471","issn":["0341-0471","0939-5075","1865-7125"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310313990","host_organization_name":"De Gruyter","host_organization_lineage":["https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zeitschrift f\u00fcr Naturforschung C","raw_type":"journal-article"},{"id":"pmid:35191282","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35191282","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zeitschrift fur Naturforschung. C, Journal of biosciences","raw_type":"Journal Article"},{"id":"pmh:oai:upcommons.upc.edu:2117/363520","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2117/363520","pdf_url":null,"source":{"id":"https://openalex.org/S4377196262","display_name":"UPCommons institutional repository (Universitat Polit\u00e8cnica de Catalunya)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I9617848","host_organization_name":"Universitat Polit\u00e8cnica de Catalunya","host_organization_lineage":["https://openalex.org/I9617848"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"}],"best_oa_location":{"id":"pmh:oai:upcommons.upc.edu:2117/363520","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2117/363520","pdf_url":null,"source":{"id":"https://openalex.org/S4377196262","display_name":"UPCommons institutional repository (Universitat Polit\u00e8cnica de Catalunya)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I9617848","host_organization_name":"Universitat Polit\u00e8cnica de Catalunya","host_organization_lineage":["https://openalex.org/I9617848"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G677695395","display_name":null,"funder_award_id":"PID2019-104111RB-I00","funder_id":"https://openalex.org/F4320322930","funder_display_name":"Ministerio de Ciencia e Innovaci\u00f3n"}],"funders":[{"id":"https://openalex.org/F4320322930","display_name":"Ministerio de Ciencia e Innovaci\u00f3n","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W38238698","https://openalex.org/W97463538","https://openalex.org/W1604648834","https://openalex.org/W1614786220","https://openalex.org/W2013637608","https://openalex.org/W2016280066","https://openalex.org/W2027071930","https://openalex.org/W2028031080","https://openalex.org/W2029361857","https://openalex.org/W2029753427","https://openalex.org/W2036543589","https://openalex.org/W2038336578","https://openalex.org/W2068896164","https://openalex.org/W2093179208","https://openalex.org/W2095524309","https://openalex.org/W2111475345","https://openalex.org/W2117000555","https://openalex.org/W2120860408","https://openalex.org/W2127951128","https://openalex.org/W2139890457","https://openalex.org/W2141409038","https://openalex.org/W2151528584","https://openalex.org/W2187227963","https://openalex.org/W2326033858","https://openalex.org/W2548334080","https://openalex.org/W2559056570","https://openalex.org/W2571716163","https://openalex.org/W2884967335","https://openalex.org/W2886868128","https://openalex.org/W2896040520","https://openalex.org/W2898134810","https://openalex.org/W2905093646","https://openalex.org/W2914144277","https://openalex.org/W2922688943","https://openalex.org/W3048553722"],"related_works":["https://openalex.org/W2914365995","https://openalex.org/W4410087166","https://openalex.org/W2086694336","https://openalex.org/W4386966679","https://openalex.org/W2896040520","https://openalex.org/W4292068845","https://openalex.org/W4320496560","https://openalex.org/W2884973486","https://openalex.org/W3185692126","https://openalex.org/W2026648244"],"abstract_inverted_index":{"Point":[0],"of":[1,11,22,62,82,91,95,102,106],"care":[2],"testing":[3],"(PoCT)":[4],"devices":[5],"permit":[6],"precise":[7],"and":[8,20,36,121,132,134],"rapid":[9,131],"detection":[10],"disease-related":[12],"biomarkers":[13],"contributing":[14],"to":[15,51],"an":[16,23],"early":[17,122],"disease":[18,120],"diagnosis":[19],"administration":[21],"appropriate":[24],"treatment.":[25],"The":[26,75,93,126],"enzyme":[27],"myeloperoxidase":[28],"(MPO)":[29],"is":[30,45,66,86,130],"a":[31,103],"relevant":[32],"biomarker":[33],"for":[34,98,114,137],"infection":[35],"inflammation":[37],"events":[38],"assessment;":[39],"however":[40],"its":[41,56],"direct":[42],"electrochemical":[43,80,100],"quantification":[44],"hindered":[46],"by":[47],"the":[48,52,63,69,79,83,89,99],"limited":[49],"accessibility":[50],"iron":[53],"atom":[54],"in":[55,78,139],"active":[57],"center.":[58],"Herein,":[59],"such":[60],"hindrance":[61],"MPO":[64,107],"biomolecule":[65],"overcome":[67],"using":[68],"redox":[70],"mediator":[71],"2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic":[72],"acid)":[73],"(ABTS).":[74],"charge":[76],"involved":[77],"reduction":[81],"MPO-oxidized":[84],"ABTS":[85,96],"correlated":[87],"with":[88],"concentration":[90],"MPO.":[92],"use":[94],"allowed":[97],"assessment":[101],"wide":[104],"range":[105],"concentrations":[108],"(10-1000":[109],"nM)":[110],"including":[111],"those":[112],"reported":[113],"wound":[115],"infections,":[116],"chronic":[117],"obstructive":[118],"pulmonary":[119],"adverse":[123],"cardiac":[124],"events.":[125],"developed":[127],"electroanalytical":[128],"approach":[129],"inexpensive,":[133],"thus":[135],"suitable":[136],"implementation":[138],"PoCT":[140],"devices.":[141]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2022-02-24T00:00:00"}