{"id":"https://openalex.org/W4212829520","doi":"https://doi.org/10.1097/qad.0000000000003194","title":"Effect of antiretroviral therapy care interruptions on mortality in children living with HIV","display_name":"Effect of antiretroviral therapy care interruptions on mortality in children living with HIV","publication_year":2022,"publication_date":"2022-02-11","ids":{"openalex":"https://openalex.org/W4212829520","doi":"https://doi.org/10.1097/qad.0000000000003194","pmid":"https://pubmed.ncbi.nlm.nih.gov/35152225","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10002475"},"language":"en","primary_location":{"id":"doi:10.1097/qad.0000000000003194","doi":"https://doi.org/10.1097/qad.0000000000003194","is_oa":false,"landing_page_url":"https://doi.org/10.1097/qad.0000000000003194","pdf_url":null,"source":{"id":"https://openalex.org/S20605092","display_name":"AIDS","issn_l":"0269-9370","issn":["0269-9370","1473-5571"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AIDS","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","datacite","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10002475/pdf/nihms-1874873.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Claire Davies","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157614274","display_name":"University of Cape Town","ror":"https://ror.org/03p74gp79","country_code":"ZA","type":"education","lineage":["https://openalex.org/I157614274"]}],"countries":["ZA"],"is_corresponding":true,"raw_author_name":"Claire Davies","raw_affiliation_strings":["Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town","institution_ids":["https://openalex.org/I157614274"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Leigh Johnson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157614274","display_name":"University of Cape Town","ror":"https://ror.org/03p74gp79","country_code":"ZA","type":"education","lineage":["https://openalex.org/I157614274"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"Leigh Johnson","raw_affiliation_strings":["Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town","institution_ids":["https://openalex.org/I157614274"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Shobna Sawry","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I192619145","display_name":"University of the Witwatersrand","ror":"https://ror.org/03rp50x72","country_code":"ZA","type":"education","lineage":["https://openalex.org/I192619145"]},{"id":"https://openalex.org/I2800088396","display_name":"Chris Hani Baragwanath Hospital","ror":"https://ror.org/02g48bh60","country_code":"ZA","type":"healthcare","lineage":["https://openalex.org/I2800088396"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"Shobna Sawry","raw_affiliation_strings":["Wits Reproductive Health and HIV Institute, University of the Witwatersrand, Harriet Shezi Children's Clinic, Chris Hani Baragwanath Academic Hospital, Soweto, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wits Reproductive Health and HIV Institute, University of the Witwatersrand, Harriet Shezi Children's Clinic, Chris Hani Baragwanath Academic Hospital, Soweto, South Africa","institution_ids":["https://openalex.org/I192619145","https://openalex.org/I2800088396"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Cleophas Chimbetete","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Cleophas Chimbetete","raw_affiliation_strings":["Newlands Clinic, Harare, Zimbabwe"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Newlands Clinic, Harare, Zimbabwe","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Brian Eley","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157614274","display_name":"University of Cape Town","ror":"https://ror.org/03p74gp79","country_code":"ZA","type":"education","lineage":["https://openalex.org/I157614274"]},{"id":"https://openalex.org/I4210157117","display_name":"Red Cross War Memorial Children's Hospital","ror":"https://ror.org/04d6eav07","country_code":"ZA","type":"healthcare","lineage":["https://openalex.org/I1307091933","https://openalex.org/I4210157117"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"Brian Eley","raw_affiliation_strings":["Red Cross War Memorial Children's Hospital and Department of Paediatrics and Child Health, University of Cape Town, Cape Town, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Red Cross War Memorial Children's Hospital and Department of Paediatrics and Child Health, University of Cape Town, Cape Town, South Africa","institution_ids":["https://openalex.org/I157614274","https://openalex.org/I4210157117"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Michael Vinikoor","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294560359","display_name":"Centre for Infectious Disease Research in Zambia","ror":"https://ror.org/02vsy6m37","country_code":"ZM","type":"nonprofit","lineage":["https://openalex.org/I1294560359"]}],"countries":["ZM"],"is_corresponding":false,"raw_author_name":"Michael Vinikoor","raw_affiliation_strings":["Centre for Infectious Disease Research in Zambia, Lusaka, Zambia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Infectious Disease Research in Zambia, Lusaka, Zambia","institution_ids":["https://openalex.org/I1294560359"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Karl-G\u00fcnter Technau","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I192619145","display_name":"University of the Witwatersrand","ror":"https://ror.org/03rp50x72","country_code":"ZA","type":"education","lineage":["https://openalex.org/I192619145"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"Karl-G\u00fcnter Technau","raw_affiliation_strings":["Empilweni Services and Research Unit, Rahima Moosa Mother and Child Hospital, Department of Paediatrics and Child Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Empilweni Services and Research Unit, Rahima Moosa Mother and Child Hospital, Department of Paediatrics and Child Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa","institution_ids":["https://openalex.org/I192619145"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jochen Ehmer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405267172","display_name":"SolidarMed","ror":"https://ror.org/01gnzna90","country_code":"CH","type":"nonprofit","lineage":["https://openalex.org/I4405267172"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Jochen Ehmer","raw_affiliation_strings":["SolidarMed, Lucerne, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"SolidarMed, Lucerne, Switzerland","institution_ids":["https://openalex.org/I4405267172"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Helena Rabie","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I26092322","display_name":"Stellenbosch University","ror":"https://ror.org/05bk57929","country_code":"ZA","type":"education","lineage":["https://openalex.org/I26092322"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"Helena Rabie","raw_affiliation_strings":["Department of Paediatrics and Child Health, Tygerberg Academic Hospital, University of Stellenbosch, Stellenbosch, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Paediatrics and Child Health, Tygerberg Academic Hospital, University of Stellenbosch, Stellenbosch, South Africa","institution_ids":["https://openalex.org/I26092322"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Sam Phiri","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800899879","display_name":"Kamuzu Central Hospital","ror":"https://ror.org/022j3nr24","country_code":"MW","type":"healthcare","lineage":["https://openalex.org/I2800899879"]},{"id":"https://openalex.org/I4210090188","display_name":"Lighthouse Trust","ror":"https://ror.org/009wrgz05","country_code":"MW","type":"healthcare","lineage":["https://openalex.org/I4210090188"]}],"countries":["MW"],"is_corresponding":false,"raw_author_name":"Sam Phiri","raw_affiliation_strings":["Lighthouse Trust Clinic, Kamuzu Central Hospital, Lilongwe, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lighthouse Trust Clinic, Kamuzu Central Hospital, Lilongwe, Malaysia","institution_ids":["https://openalex.org/I2800899879","https://openalex.org/I4210090188"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077160522","display_name":"Frank Courteney Tanser","orcid":"https://orcid.org/0000-0001-9797-0000","observed_orcids":["https://orcid.org/0000-0001-9797-0000"]},"institutions":[{"id":"https://openalex.org/I95023434","display_name":"University of KwaZulu-Natal","ror":"https://ror.org/04qzfn040","country_code":"ZA","type":"education","lineage":["https://openalex.org/I95023434"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"Frank Tanser","raw_affiliation_strings":["Africa Centre for Health and Population Studies, University of KwaZulu-Natal, Somkhele, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Africa Centre for Health and Population Studies, University of KwaZulu-Natal, Somkhele, South Africa","institution_ids":["https://openalex.org/I95023434"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Kennedy Malisita","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210163380","display_name":"Queen Elizabeth Central Hospital","ror":"https://ror.org/025sthg37","country_code":"MW","type":"healthcare","lineage":["https://openalex.org/I4210163380"]}],"countries":["MW"],"is_corresponding":false,"raw_author_name":"Kennedy Malisita","raw_affiliation_strings":["Queen Elizabeth Central Hospital, Blantyre, Malawi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Queen Elizabeth Central Hospital, Blantyre, Malawi","institution_ids":["https://openalex.org/I4210163380"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Geoffrey Fatti","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I26092322","display_name":"Stellenbosch University","ror":"https://ror.org/05bk57929","country_code":"ZA","type":"education","lineage":["https://openalex.org/I26092322"]},{"id":"https://openalex.org/I4210135048","display_name":"Kheth\u2019Impilo","ror":"https://ror.org/03tv0yw82","country_code":"ZA","type":"nonprofit","lineage":["https://openalex.org/I4210135048"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"Geoffrey Fatti","raw_affiliation_strings":["Division of Epidemiology and Biostatistics, Department of Global Health, Stellenbosch University","Kheth\u2019Impilo AIDS Free Living"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Epidemiology and Biostatistics, Department of Global Health, Stellenbosch University","institution_ids":["https://openalex.org/I26092322"]},{"raw_affiliation_string":"Kheth\u2019Impilo AIDS Free Living","institution_ids":["https://openalex.org/I4210135048"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Meg Osler","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157614274","display_name":"University of Cape Town","ror":"https://ror.org/03p74gp79","country_code":"ZA","type":"education","lineage":["https://openalex.org/I157614274"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"Meg Osler","raw_affiliation_strings":["Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town","institution_ids":["https://openalex.org/I157614274"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064614188","display_name":"Robin Wood","orcid":"https://orcid.org/0000-0002-4276-7117","observed_orcids":["https://orcid.org/0000-0002-4276-7117"]},"institutions":[{"id":"https://openalex.org/I157614274","display_name":"University of Cape Town","ror":"https://ror.org/03p74gp79","country_code":"ZA","type":"education","lineage":["https://openalex.org/I157614274"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"Robin Wood","raw_affiliation_strings":["Gugulethu HIV Programme and Desmond Tutu HIV Centre, University of Cape Town, Cape Town, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gugulethu HIV Programme and Desmond Tutu HIV Centre, University of Cape Town, Cape Town, South Africa","institution_ids":["https://openalex.org/I157614274"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Sam Newton","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28046988","display_name":"Kwame Nkrumah University of Science and Technology","ror":"https://ror.org/00cb23x68","country_code":"GH","type":"education","lineage":["https://openalex.org/I28046988"]}],"countries":["GH"],"is_corresponding":false,"raw_author_name":"Sam Newton","raw_affiliation_strings":["School of Public Health, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Public Health, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana","institution_ids":["https://openalex.org/I28046988"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Andreas Haas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I118564535","display_name":"University of Bern","ror":"https://ror.org/02k7v4d05","country_code":"CH","type":"education","lineage":["https://openalex.org/I118564535"]},{"id":"https://openalex.org/I4210135124","display_name":"Institute of Social and Preventive Medicine","ror":"https://ror.org/038esz880","country_code":"CH","type":"facility","lineage":["https://openalex.org/I2802229882","https://openalex.org/I4210135124","https://openalex.org/I4210149340","https://openalex.org/I97565354"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Andreas Haas","raw_affiliation_strings":["Institute of Social and Preventive Medicine, University of Bern, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Social and Preventive Medicine, University of Bern, Switzerland","institution_ids":["https://openalex.org/I118564535","https://openalex.org/I4210135124"]}]},{"author_position":"last","author":{"id":null,"display_name":"Mary-Ann Davies","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157614274","display_name":"University of Cape Town","ror":"https://ror.org/03p74gp79","country_code":"ZA","type":"education","lineage":["https://openalex.org/I157614274"]}],"countries":["ZA"],"is_corresponding":true,"raw_author_name":"Mary-Ann Davies","raw_affiliation_strings":["Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town","institution_ids":["https://openalex.org/I157614274"]}]}],"institutions":[],"countries_distinct_count":5,"institutions_distinct_count":15,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I157614274"],"apc_list":null,"apc_paid":null,"fwci":0.9727,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.7434558,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":92,"max":97},"biblio":{"volume":"36","issue":"5","first_page":"729","last_page":"737"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11556","display_name":"Poverty, Education, and Child Welfare","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/3311","display_name":"Safety Research"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10209","display_name":"Global Maternal and Child Health","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pediatric-hiv","display_name":"pediatric HIV","score":0.75},{"id":"https://openalex.org/keywords/antiretroviral-therapy","display_name":"antiretroviral therapy","score":0.9789999723434448},{"id":"https://openalex.org/keywords/loss-to-follow-up","display_name":"loss to follow-up","score":0.9470000267028809},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.5490000247955322},{"id":"https://openalex.org/keywords/retention-in-care","display_name":"retention in care","score":0.9629999995231628},{"id":"https://openalex.org/keywords/early-art-initiation","display_name":"early ART initiation","score":0.7820000052452087},{"id":"https://openalex.org/keywords/hiv-infected-children","display_name":"HIV-infected children","score":0.5419999957084656}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9078999757766724},{"id":"https://openalex.org/C2993143319","wikidata":"https://www.wikidata.org/wiki/Q583050","display_name":"Antiretroviral therapy","level":4,"score":0.6128000020980835},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.5927000045776367},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.5867000222206116},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.5486000180244446},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.49149999022483826},{"id":"https://openalex.org/C160735492","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Health care","level":2,"score":0.4609000086784363},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.36059999465942383},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.3458000123500824},{"id":"https://openalex.org/C2776452011","wikidata":"https://www.wikidata.org/wiki/Q311463","display_name":"Sida","level":4,"score":0.31690001487731934},{"id":"https://openalex.org/C124306116","wikidata":"https://www.wikidata.org/wiki/Q2512965","display_name":"Ambulatory care","level":3,"score":0.3154999911785126},{"id":"https://openalex.org/C2777215511","wikidata":"https://www.wikidata.org/wiki/Q1870656","display_name":"Lost to follow-up","level":2,"score":0.31299999356269836},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.3052000105381012},{"id":"https://openalex.org/C3019165603","wikidata":"https://www.wikidata.org/wiki/Q583050","display_name":"Antiretroviral treatment","level":5,"score":0.30469998717308044},{"id":"https://openalex.org/C986699","wikidata":"https://www.wikidata.org/wiki/Q7939","display_name":"El Ni\u00f1o","level":2,"score":0.30320000648498535},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.2856999933719635},{"id":"https://openalex.org/C2993624421","wikidata":"https://www.wikidata.org/wiki/Q16917","display_name":"Hospital care","level":3,"score":0.27649998664855957},{"id":"https://openalex.org/C138816342","wikidata":"https://www.wikidata.org/wiki/Q189603","display_name":"Public health","level":2,"score":0.2655999958515167},{"id":"https://openalex.org/C205545832","wikidata":"https://www.wikidata.org/wiki/Q17156455","display_name":"Young adult","level":2,"score":0.26489999890327454},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.26350000500679016},{"id":"https://openalex.org/C83864248","wikidata":"https://www.wikidata.org/wiki/Q177323","display_name":"Developing country","level":2,"score":0.2630000114440918},{"id":"https://openalex.org/C179755657","wikidata":"https://www.wikidata.org/wiki/Q58702","display_name":"Mortality rate","level":2,"score":0.26170000433921814},{"id":"https://openalex.org/C160050368","wikidata":"https://www.wikidata.org/wiki/Q132453","display_name":"Developed country","level":3,"score":0.2538999915122986},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.2531999945640564}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000353","descriptor_name":"Africa, Southern","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D016016","descriptor_name":"Proportional Hazards Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019380","descriptor_name":"Anti-HIV Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true}],"locations_count":6,"locations":[{"id":"doi:10.1097/qad.0000000000003194","doi":"https://doi.org/10.1097/qad.0000000000003194","is_oa":false,"landing_page_url":"https://doi.org/10.1097/qad.0000000000003194","pdf_url":null,"source":{"id":"https://openalex.org/S20605092","display_name":"AIDS","issn_l":"0269-9370","issn":["0269-9370","1473-5571"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AIDS","raw_type":"journal-article"},{"id":"pmid:35152225","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35152225","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AIDS (London, England)","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10002475","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10002475","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10002475/pdf/nihms-1874873.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"AIDS","raw_type":"Text"},{"id":"pmh:doi:10.48350/165647","doi":null,"is_oa":false,"landing_page_url":"https://boris-portal.unibe.ch/handle/20.500.12422/67546","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"},{"id":"pmh:oai:boris.unibe.ch:165647","doi":null,"is_oa":true,"landing_page_url":"https://boris.unibe.ch/165647/","pdf_url":null,"source":{"id":"https://openalex.org/S4306401747","display_name":"BORIS (University Library Bern)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210103840","host_organization_name":"Nakuru County Council","host_organization_lineage":["https://openalex.org/I4210103840"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"doi:10.48350/165647","doi":"https://doi.org/10.48350/165647","is_oa":true,"landing_page_url":"https://doi.org/10.48350/165647","pdf_url":null,"source":{"id":"https://openalex.org/S7407053152","display_name":"Open Access CRIS of the University of Bern","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:10002475","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10002475","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10002475/pdf/nihms-1874873.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"AIDS","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G9000915114","display_name":"International epidemiology Databases to Evaluate AIDS (IeDEA) Southern Africa.","funder_award_id":"U01AI069924","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4212829520.pdf","grobid_xml":"https://content.openalex.org/works/W4212829520.grobid-xml"},"referenced_works_count":22,"referenced_works":["https://openalex.org/W986956689","https://openalex.org/W1969748111","https://openalex.org/W1971077001","https://openalex.org/W1973854903","https://openalex.org/W1983901054","https://openalex.org/W2025656757","https://openalex.org/W2033412631","https://openalex.org/W2033853316","https://openalex.org/W2066534928","https://openalex.org/W2073347306","https://openalex.org/W2073848632","https://openalex.org/W2087953584","https://openalex.org/W2135206837","https://openalex.org/W2139207583","https://openalex.org/W2144304933","https://openalex.org/W2153189426","https://openalex.org/W2159365635","https://openalex.org/W2171618626","https://openalex.org/W2315992637","https://openalex.org/W2324276317","https://openalex.org/W2411800748","https://openalex.org/W2728753402"],"related_works":["https://openalex.org/W4226420886","https://openalex.org/W6958982891","https://openalex.org/W1984336534","https://openalex.org/W1968188985","https://openalex.org/W2913945995","https://openalex.org/W4399171782","https://openalex.org/W2520680373","https://openalex.org/W2973985925","https://openalex.org/W2403428174","https://openalex.org/W2883327071"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"evaluate":[2],"the":[3,16,122,243],"characteristics":[4],"and":[5,20,36,86,128,178],"outcomes":[6],"of":[7,22,97,163,238],"HIV-infected":[8],"children":[9,31,154,239],"that":[10,235],"have":[11],"care":[12,78,119,133,161,171,185,198,218,241],"interruptions,":[13],"during":[14],"which":[15,164],"child's":[17],"health":[18],"status":[19],"use":[21],"medication":[23],"is":[24,249],"unknown.":[25],"DESIGN:":[26],"We":[27],"included":[28],"data":[29],"on":[30,126,138,176,190,203,223],"initiating":[32],"ART":[33,98,177,204,224,247,254],"between":[34],"2004":[35],"2016":[37],"at":[38,44],"less":[39],"than":[40,72],"16":[41,45],"years":[42],"old":[43],"International":[46],"Epidemiologic":[47],"Databases":[48],"to":[49,60,89,251],"Evaluate":[50],"AIDS":[51],"Southern":[52],"Africa":[53],"cohorts.":[54],"Children":[55,75,91],"were":[56,82,100,113,143],"classified":[57,83],"as":[58,84],"loss":[59],"follow":[61],"up":[62],"(LTFU)":[63],"if":[64,80],"they":[65,81],"had":[66,76,159,168,182],"not":[67,215],"attended":[68],"clinic":[69],"for":[70],"more":[71],"180":[73,95],"days.":[74],"a":[77,117,131,146,160,169,183,197,217],"interruption":[79,120,134,172,186,199,219],"LTFU,":[85],"subsequently":[87],"returned":[88],"care.":[90],"who":[92],"died":[93],"within":[94,121,173,200],"days":[96],"start":[99],"excluded.":[101],"METHODS:":[102],"The":[103,232],"main":[104],"outcome":[105],"was":[106,194],"all":[107],"cause":[108],"mortality.":[109],"Two":[110],"exposed":[111],"groups":[112],"considered:":[114],"those":[115,129],"with":[116,130,196,216],"first":[118,123,132,170,184],"6":[124,136,174,188,201,221],"months":[125,137,175,189,202,222],"ART,":[127],"after":[135,187,220,246],"ART.":[139,191],"Adjusted":[140],"hazard":[141,206],"ratios":[142],"determined":[144],"using":[145],"Cox":[147],"regression":[148],"model.":[149],"RESULTS:":[150],"Among":[151],"53":[152],"674":[153],"included,":[155],"23":[156],"437":[157],"(44%)":[158],"interruption,":[162],"10":[165],"629":[166],"(20%)":[167],"12":[179],"808":[180],"(24%)":[181],"Increased":[192],"mortality":[193],"associated":[195],"[adjusted":[205],"ratio":[207],"(AHR)":[208],"=":[209,226],"1.52,":[210],"95%":[211,228],"CI":[212,229],"1.12-2.04]":[213],"but":[214],"(AHR":[225],"1.05,":[227],"0.77-1.44).":[230],"CONCLUSION:":[231],"findings":[233],"suggest":[234],"strengthening":[236],"retention":[237],"in":[240,242],"early":[244],"period":[245],"initiation":[248],"critical":[250],"improving":[252],"paediatric":[253],"outcomes.":[255]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2022-02-24T00:00:00"}