{"id":"https://openalex.org/W4211108398","doi":"https://doi.org/10.1002/14651858.cd003200.pub8","title":"Exercise therapy for chronic fatigue syndrome","display_name":"Exercise therapy for chronic fatigue syndrome","publication_year":2019,"publication_date":"2019-10-02","ids":{"openalex":"https://openalex.org/W4211108398","doi":"https://doi.org/10.1002/14651858.cd003200.pub8"},"language":"en","primary_location":{"id":"doi:10.1002/14651858.cd003200.pub8","doi":"https://doi.org/10.1002/14651858.cd003200.pub8","is_oa":false,"landing_page_url":"https://doi.org/10.1002/14651858.cd003200.pub8","pdf_url":null,"source":{"id":"https://openalex.org/S4210172715","display_name":"Cochrane Database of Systematic Reviews","issn_l":"1361-6137","issn":["1361-6137","1464-780X","1465-184X","1465-1858","1469-493X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-1","jufo-2","ki-jl-2","medline","norway-1","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cochrane Database of Systematic Reviews","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086714273","display_name":"Lillebeth Larun","orcid":"https://orcid.org/0000-0003-2012-7116","observed_orcids":["https://orcid.org/0000-0003-2012-7116"]},"institutions":[{"id":"https://openalex.org/I1333353642","display_name":"Norwegian Institute of Public Health","ror":"https://ror.org/046nvst19","country_code":"NO","type":"government","lineage":["https://openalex.org/I1333353642","https://openalex.org/I4210149801","https://openalex.org/I4210163359"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Lillebeth Larun","raw_affiliation_strings":["Division for Health Services; Norwegian Institute of Public Health; Oslo Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division for Health Services; Norwegian Institute of Public Health; Oslo Norway","institution_ids":["https://openalex.org/I1333353642"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028452551","display_name":"Kjetil Gundro Brurberg","orcid":"https://orcid.org/0000-0002-5920-4652","observed_orcids":["https://orcid.org/0000-0002-5920-4652"]},"institutions":[{"id":"https://openalex.org/I1333353642","display_name":"Norwegian Institute of Public Health","ror":"https://ror.org/046nvst19","country_code":"NO","type":"government","lineage":["https://openalex.org/I1333353642","https://openalex.org/I4210149801","https://openalex.org/I4210163359"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Kjetil G Brurberg","raw_affiliation_strings":["Division for Health Services; Norwegian Institute of Public Health; Oslo Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division for Health Services; Norwegian Institute of Public Health; Oslo Norway","institution_ids":["https://openalex.org/I1333353642"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073472392","display_name":"Jan Odgaard\u2010Jensen","orcid":"https://orcid.org/0000-0001-6776-1849","observed_orcids":["https://orcid.org/0000-0001-6776-1849"]},"institutions":[{"id":"https://openalex.org/I4387155556","display_name":"Medicinr\u00e5det","ror":"https://ror.org/03az8b907","country_code":"DK","type":"other","lineage":["https://openalex.org/I4387155556"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Jan Odgaard-Jensen","raw_affiliation_strings":["Medicinr\u00e5det; K\u00f8benhavn \u00d8 Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicinr\u00e5det; K\u00f8benhavn \u00d8 Denmark","institution_ids":["https://openalex.org/I4387155556"]}]},{"author_position":"last","author":{"id":null,"display_name":"Jonathan R Price","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jonathan R Price","raw_affiliation_strings":["Department of Psychiatry; University of Oxford; Oxford UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry; University of Oxford; Oxford UK","institution_ids":["https://openalex.org/I40120149"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5000,"currency":"USD","value_usd":5000},"apc_paid":null,"fwci":2.1073,"has_fulltext":false,"cited_by_count":139,"citation_normalized_percentile":{"value":0.8960199,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"2021","issue":"3","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11282","display_name":"Fibromyalgia and Chronic Fatigue Syndrome Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11282","display_name":"Fibromyalgia and Chronic Fatigue Syndrome Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11368","display_name":"Long-Term Effects of COVID-19","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10084","display_name":"Musculoskeletal pain and rehabilitation","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3612","display_name":"Physical Therapy, Sports Therapy and Rehabilitation"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-fatigue-syndrome","display_name":"chronic fatigue syndrome","score":0.9959999918937683},{"id":"https://openalex.org/keywords/exercise-therapy","display_name":"exercise therapy","score":0.9980000257492065},{"id":"https://openalex.org/keywords/aerobic-exercise","display_name":"aerobic exercise","score":0.9860000014305115},{"id":"https://openalex.org/keywords/anaerobic-exercise","display_name":"anaerobic exercise","score":0.8510000109672546},{"id":"https://openalex.org/keywords/fatigue","display_name":"fatigue","score":0.6990000009536743},{"id":"https://openalex.org/keywords/physical-functioning","display_name":"physical function","score":0.8349999785423279},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.8159999847412109},{"id":"https://openalex.org/keywords/pain","display_name":"pain","score":0.5519999861717224},{"id":"https://openalex.org/keywords/sleep","display_name":"sleep","score":0.6700000166893005},{"id":"https://openalex.org/keywords/mood-disorders","display_name":"mood disorders","score":0.8410000205039978},{"id":"https://openalex.org/keywords/cognitive-behavioral-therapy","display_name":"cognitive behavioral therapy","score":0.460999995470047},{"id":"https://openalex.org/keywords/pacing","display_name":"pacing","score":0.7540000081062317},{"id":"https://openalex.org/keywords/treatment-discontinuation","display_name":"treatment discontinuation","score":0.5120000243186951},{"id":"https://openalex.org/keywords/health-care-utilization","display_name":"health care utilization","score":0.7170000076293945},{"id":"https://openalex.org/keywords/long-term-follow-up","display_name":"long-term follow-up","score":0.5709999799728394},{"id":"https://openalex.org/keywords/exercise-intensity","display_name":"exercise intensity","score":0.3529999852180481},{"id":"https://openalex.org/keywords/exercise-duration","display_name":"exercise duration","score":0.35100001096725464},{"id":"https://openalex.org/keywords/exercise-frequency","display_name":"exercise frequency","score":0.40400001406669617}],"concepts":[{"id":"https://openalex.org/C2779566273","wikidata":"https://www.wikidata.org/wiki/Q209733","display_name":"Chronic fatigue syndrome","level":2,"score":0.8534893989562988},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8057689666748047},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.6277127265930176},{"id":"https://openalex.org/C2777466982","wikidata":"https://www.wikidata.org/wiki/Q5227287","display_name":"Data extraction","level":3,"score":0.5352547764778137},{"id":"https://openalex.org/C2780733359","wikidata":"https://www.wikidata.org/wiki/Q331769","display_name":"Mood","level":2,"score":0.5260341763496399},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.4904934763908386},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.46788567304611206},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.4311584532260895},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.4239477515220642},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.41956573724746704},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.2142186164855957},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.15491271018981934},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/14651858.cd003200.pub8","doi":"https://doi.org/10.1002/14651858.cd003200.pub8","is_oa":false,"landing_page_url":"https://doi.org/10.1002/14651858.cd003200.pub8","pdf_url":null,"source":{"id":"https://openalex.org/S4210172715","display_name":"Cochrane Database of Systematic Reviews","issn_l":"1361-6137","issn":["1361-6137","1464-780X","1465-184X","1465-1858","1469-493X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-1","jufo-2","ki-jl-2","medline","norway-1","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cochrane Database of Systematic Reviews","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":87,"referenced_works":["https://openalex.org/W16460120","https://openalex.org/W1499972928","https://openalex.org/W1513006351","https://openalex.org/W1517101073","https://openalex.org/W1538919177","https://openalex.org/W1551649033","https://openalex.org/W1758747032","https://openalex.org/W1818735808","https://openalex.org/W1845447069","https://openalex.org/W1870459929","https://openalex.org/W1886523332","https://openalex.org/W1977185679","https://openalex.org/W1978040764","https://openalex.org/W1981138990","https://openalex.org/W1989479397","https://openalex.org/W1989608621","https://openalex.org/W1997295778","https://openalex.org/W2007615478","https://openalex.org/W2007887341","https://openalex.org/W2008925929","https://openalex.org/W2011960511","https://openalex.org/W2012988619","https://openalex.org/W2015709747","https://openalex.org/W2025129717","https://openalex.org/W2027451332","https://openalex.org/W2028236461","https://openalex.org/W2035398560","https://openalex.org/W2037377025","https://openalex.org/W2051943304","https://openalex.org/W2060590254","https://openalex.org/W2062547500","https://openalex.org/W2064648786","https://openalex.org/W2074158819","https://openalex.org/W2081981544","https://openalex.org/W2089899324","https://openalex.org/W2091604266","https://openalex.org/W2098287790","https://openalex.org/W2100043554","https://openalex.org/W2103654910","https://openalex.org/W2104183896","https://openalex.org/W2106060394","https://openalex.org/W2106174658","https://openalex.org/W2106406245","https://openalex.org/W2112802342","https://openalex.org/W2114242035","https://openalex.org/W2123921426","https://openalex.org/W2124473907","https://openalex.org/W2125435699","https://openalex.org/W2127088103","https://openalex.org/W2128868698","https://openalex.org/W2130235475","https://openalex.org/W2134945464","https://openalex.org/W2135552648","https://openalex.org/W2136088258","https://openalex.org/W2136415723","https://openalex.org/W2138106733","https://openalex.org/W2141294075","https://openalex.org/W2143155193","https://openalex.org/W2145233279","https://openalex.org/W2145555293","https://openalex.org/W2150427878","https://openalex.org/W2151487996","https://openalex.org/W2155523469","https://openalex.org/W2155596333","https://openalex.org/W2157380735","https://openalex.org/W2157823046","https://openalex.org/W2161529602","https://openalex.org/W2166281097","https://openalex.org/W2167056725","https://openalex.org/W2171701188","https://openalex.org/W2172000223","https://openalex.org/W2177974532","https://openalex.org/W2235276349","https://openalex.org/W2282810411","https://openalex.org/W2320909684","https://openalex.org/W2382763310","https://openalex.org/W2468838639","https://openalex.org/W2520579059","https://openalex.org/W2676174492","https://openalex.org/W2901469734","https://openalex.org/W3090293687","https://openalex.org/W3143129303","https://openalex.org/W3147026063","https://openalex.org/W4234639253","https://openalex.org/W4292806894","https://openalex.org/W6638858990","https://openalex.org/W6685332499"],"related_works":["https://openalex.org/W2410804831","https://openalex.org/W4416449957","https://openalex.org/W2762250369","https://openalex.org/W2359275170","https://openalex.org/W1269213174","https://openalex.org/W7154490734","https://openalex.org/W4410591767","https://openalex.org/W2610310540","https://openalex.org/W2189249500","https://openalex.org/W2398975179"],"abstract_inverted_index":{"Background":[0],"Chronic":[1],"fatigue":[2,17,426,460,608,745,859,905],"syndrome":[3],"(CFS)":[4],"or":[5,93,242,316,330,367,589,604,626,682,693,700,723,839,853,892,914,942,963,967],"myalgic":[6],"encephalomyelitis":[7],"(ME)":[8],"is":[9,29,67,461,473,516,545,553,583,587,659,729,872,922,929],"a":[10,140,197,400,408,901],"serious":[11,507,650,795],"disorder":[12],"characterised":[13],"by":[14,47],"persistent":[15],"postexertional":[16],"and":[18,25,61,117,133,148,153,177,216,229,309,350,392,413,567,581,688,697,767,825,860,961],"substantial":[19],"symptoms":[20,60],"related":[21],"to":[22,39,58,77,136,167,209,296,347,436,450,454,482,494,498,524,607,618,635,667,717,755,759,776,780,803,828,911,925,931],"cognitive,":[23],"immune":[24],"autonomous":[26],"dysfunction.":[27],"There":[28],"no":[30,605,683,701],"specific":[31],"diagnostic":[32,35,50,204],"test,":[33],"therefore":[34],"criteria":[36,51,187,954,973],"are":[37,457,501,644,711,789,847],"used":[38,321,353],"diagnose":[40],"CFS.":[41],"The":[42,71,299,571,673,812,875,917],"prevalence":[43],"of":[44,49,73,81,103,143,174,200,226,236,250,275,306,338,340,359,403,411,429,470,506,513,539,550,565,573,579,590,611,649,656,721,730,748,794,837,869,889,938,955],"CFS":[45,87,147,909],"varies":[46],"type":[48],"used.":[52],"Existing":[53],"treatment":[54,65,308,363,389,394,430,566,612,749],"strategies":[55],"primarily":[56],"aim":[57],"relieve":[59],"improve":[62,534,561,821],"function.":[63],"One":[64],"option":[66],"exercise":[68,82,212,323,343,574,686,714,817,850],"therapy.":[69,213],"Objectives":[70],"objective":[72],"this":[74],"review":[75,219],"was":[76],"determine":[78],"the":[79,123,157,181,273,304,307,341,464,468,471,504,511,514,542,548,551,647,654,657,704,727,792,867,870,935,956,964],"effects":[80,921],"therapy":[83,291,373,378,417,423,531,557,575,595,600,687,715,735,741,818,842,898],"for":[84,146,183,958],"adults":[85,195,907],"with":[86,89,196,285,419,597,737,844,856,908,949,952],"compared":[88,418,596,716,736,827,843,910],"any":[90],"other":[91,943,972],"intervention":[92],"control":[94,421],"on":[95,258,576,706,882,904],"fatigue,":[96],"adverse":[97,508,651,796,883,920],"outcomes,":[98],"pain,":[99,577,885],"physical":[100,535,691,822,886],"functioning,":[101,823,887],"quality":[102,578,720,836,888],"life,":[104,890],"mood":[105],"disorders,":[106],"sleep,":[107],"self\u2010perceived":[108],"changes":[109],"in":[110,180,211,336,463,690,703,854,906],"overall":[111],"health,":[112],"health":[113],"service":[114],"resources":[115],"use":[116],"dropout.":[118],"Search":[119],"methods":[120],"We":[121,150,170,188,232,263,271,281,456,500,643,710,788,846],"searched":[122],"Cochrane":[124],"Common":[125],"Mental":[126],"Disorders":[127],"Group":[128],"controlled":[129,191],"trials":[130,192],"register,":[131],"CENTRAL,":[132],"SPORTDiscus":[134],"up":[135,166],"May":[137,168],"2014,":[138],"using":[139,238,267,277,971],"comprehensive":[141],"list":[142],"free\u2010text":[144],"terms":[145,337],"exercise.":[149,355],"located":[151],"unpublished":[152],"ongoing":[154],"studies":[155,300,320,398,834,946],"through":[156],"World":[158],"Health":[159],"Organization":[160],"International":[161],"Clinical":[162],"Trials":[163],"Registry":[164],"Platform":[165],"2014.":[169],"screened":[171],"reference":[172],"lists":[173],"retrieved":[175],"articles":[176],"contacted":[178],"experts":[179],"field":[182],"additional":[184],"studies.":[185],"Selection":[186],"included":[189,282,877],"randomised":[190],"(RCTs)":[193],"about":[194,503,646,791,934],"primary":[198],"diagnosis":[199],"CFS,":[201],"from":[202,287,293,344],"all":[203],"criteria,":[205,966],"who":[206],"were":[207,947],"able":[208],"participate":[210],"Data":[214],"collection":[215],"analysis":[217],"Two":[218],"authors":[220],"independently":[221],"performed":[222],"study":[223,352,878],"selection,":[224],"'Risk":[225],"bias'":[227],"assessments":[228],"data":[230,286],"extraction.":[231],"combined":[233,264],"continuous":[234],"measures":[235],"outcomes":[237,266],"mean":[239,244],"differences":[240,245],"(MDs)":[241],"standardised":[243],"(SMDs).":[246],"To":[247],"facilitate":[248],"interpretation":[249],"SMDs,":[251],"we":[252],"re\u2010expressed":[253,444,488],"SMD":[254],"estimates":[255],"as":[256,326,364,866],"MDs":[257],"more":[259,862],"common":[260],"measurement":[261],"scales.":[262],"dichotomous":[265],"risk":[268,402,410,505,648,793],"ratios":[269],"(RRs).":[270],"assessed":[272],"certainty":[274,469,512,549,655,868],"evidence":[276,472,515,552,586,658,675,728,814,871,918,927],"GRADE.":[278],"Main":[279],"results":[280],"eight":[283],"RCTs":[284],"1518":[288],"participants.":[289],"Exercise":[290,416,422,530,556,594,599,734,740,841,897],"lasted":[292],"12":[294],"weeks":[295,315],"26":[297],"weeks.":[298,318],"measured":[301],"effect":[302,544,572,705,903],"at":[303,310,333,427,537,563,568,609,627,746,768],"end":[305,428,538,564,610,747],"long\u2010term":[311,543,628,769,893],"follow\u2010up,":[312],"after":[313],"50":[314],"72":[317],"Seven":[319],"aerobic":[322,342],"therapies":[324],"such":[325],"walking,":[327],"swimming,":[328],"cycling":[329],"dancing,":[331],"provided":[332],"mixed":[334],"levels":[335],"intensity":[339],"very":[345,474,517,554,591,660,731,809,873],"low":[346,401,475,518,592,661,732],"quite":[348],"rigorous,":[349],"one":[351,876],"anaerobic":[354],"Control":[356,960],"groups":[357],"consisted":[358],"passive":[360,915],"control,":[361],"including":[362],"usual,":[365],"relaxation":[366],"flexibility":[368],"(eight":[369],"studies);":[370,376],"cognitive":[371,377],"behavioural":[372],"(CBT)":[374],"(two":[375],"(one":[379,383,386,390,395],"study);":[380,384,387],"supportive":[381],"listening":[382],"pacing":[385,739,830,941],"pharmacological":[388],"study)":[391],"combination":[393,855],"study).":[396],"Most":[397],"had":[399,407],"selection":[404],"bias.":[405,415],"All":[406,945],"high":[409],"performance":[412],"detection":[414],"'passive'":[420],"probably":[424,698,899],"reduces":[425,724,858],"(SMD":[431,476,630],"\u22120.66,":[432],"95%":[433,447,491,521,615,632,664,752,773,800],"CI":[434,448,480,492,522,616,633,665,753,774,801],"\u22121.01":[435],"\u22120.31;":[437],"7":[438],"studies,":[439,485,638],"840":[440],"participants;":[441,487,623,640,764,785,808],"moderate\u2010certainty":[442,641],"evidence;":[443],"MD":[445,489],"\u22123.4,":[446],"\u22125.3":[449],"\u22121.6;":[451],"scale":[452,496,757,778],"0":[453,497,758,779],"33).":[455,499],"uncertain":[458,502,546,584,645,712,790,848],"if":[459,713,849],"reduced":[462],"long":[465,569],"term":[466],"because":[467,510,547,585,653,726],"\u22120.62,":[477],"95":[478],"%":[479],"\u22121.32":[481],"0.07;":[483],"4":[484],"670":[486],"\u22123.2,":[490],"\u22126.9":[493],"0.4;":[495],"reactions":[509,652,797],"(RR":[519,662,798],"0.99,":[520,799],"0.14":[523,802],"6.97;":[525,804],"1":[526,620,669,761,782,805],"study,":[527,621,670,762,783,806],"319":[528,807],"participants).":[529,672],"may":[532,558,601,679,742,819,974],"moderately":[533],"functioning":[536,692],"treatment,":[540],"but":[541],"low.":[555,874],"also":[559],"slightly":[560,743,820],"sleep":[562,694,826,891],"term.":[570],"life":[580,722,838],"depression":[582,707,824,861],"missing":[588],"certainty.":[593,733],"CBT":[598,689,718],"make":[602],"little":[603,681,699],"difference":[606,684,702],"(MD":[613,750,771],"0.20,":[614],"\u20101.49":[617],"1.89;":[619],"298":[622],"low\u2010certainty":[624,765,786,810],"evidence),":[625],"follow\u2010up":[629,770],"0.07,":[631],"\u22120.13":[634],"0.28;":[636],"2":[637],"351":[639],"evidence).":[642,709,787,811,832],"0.67,":[663],"0.11":[666],"3.96;":[668],"321":[671],"available":[674,813],"suggests":[676,815],"that":[677,816],"there":[678],"be":[680],"between":[685],"(low\u2010certainty":[695,831],"evidence)":[696,766],"(moderate\u2010certainty":[708],"improves":[719],"pain":[725],"adaptive":[738,829,940],"reduce":[744],"\u22122.00,":[751],"\u22123.57":[754],"\u22120.43;":[756],"33;":[760,781],"305":[763],"\u22122.50,":[772],"\u22124.16":[775],"\u22120.84;":[777],"307":[784],"No":[833],"reported":[835],"pain.":[840],"antidepressants":[845],"therapy,":[851],"alone":[852],"antidepressants,":[857],"than":[863],"antidepressant":[864],"alone,":[865],"did":[879],"not":[880],"report":[881],"reactions,":[884],"results.":[894],"Authors'":[895],"conclusions":[896,933],"has":[900],"positive":[902],"usual":[912],"care":[913],"therapies.":[916],"regarding":[919],"uncertain.":[923],"Due":[924],"limited":[926],"it":[928],"difficult":[930],"draw":[932],"comparative":[936],"effectiveness":[937],"CBT,":[939],"interventions.":[944],"conducted":[948],"outpatients":[950],"diagnosed":[951,970],"1994":[953],"Centers":[957],"Disease":[959],"Prevention":[962],"Oxford":[965],"both.":[968],"Patients":[969],"experience":[975],"different":[976],"effects.":[977]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":15},{"year":2024,"cited_by_count":31},{"year":2023,"cited_by_count":25},{"year":2022,"cited_by_count":17},{"year":2021,"cited_by_count":21},{"year":2020,"cited_by_count":21},{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2022-02-13T00:00:00"}
