{"id":"https://openalex.org/W4211069669","doi":"https://doi.org/10.1016/j.envpol.2022.118994","title":"Semen quality and sperm DNA methylation in relation to long-term exposure to air pollution in fertile men: A cross-sectional study","display_name":"Semen quality and sperm DNA methylation in relation to long-term exposure to air pollution in fertile men: A cross-sectional study","publication_year":2022,"publication_date":"2022-02-12","ids":{"openalex":"https://openalex.org/W4211069669","doi":"https://doi.org/10.1016/j.envpol.2022.118994","pmid":"https://pubmed.ncbi.nlm.nih.gov/35167929"},"language":"en","primary_location":{"id":"doi:10.1016/j.envpol.2022.118994","doi":"https://doi.org/10.1016/j.envpol.2022.118994","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.envpol.2022.118994","pdf_url":null,"source":{"id":"https://openalex.org/S201530359","display_name":"Environmental Pollution","issn_l":"0269-7491","issn":["0269-7491","1873-6424"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environmental Pollution","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.envpol.2022.118994","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101986680","display_name":"Yu\u2010Ting Cheng","orcid":"https://orcid.org/0000-0001-9101-8430","observed_orcids":["https://orcid.org/0000-0001-9101-8430"]},"institutions":[{"id":"https://openalex.org/I4391767661","display_name":"State Key Laboratory of Reproductive Medicine","ror":"https://ror.org/00cagf561","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuting Cheng","raw_affiliation_strings":["State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China; Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China; Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]},{"raw_affiliation_string":"Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I83519826"]},{"raw_affiliation_string":"State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078356403","display_name":"Qiuqin Tang","orcid":"https://orcid.org/0000-0001-9110-9973","observed_orcids":["https://orcid.org/0000-0001-9110-9973"]},"institutions":[{"id":"https://openalex.org/I4210100029","display_name":"Nanjing Maternity and Child Health Care Hospital","ror":"https://ror.org/01a2gef28","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210100029"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qiuqin Tang","raw_affiliation_strings":["Department of Obstetrics, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China","institution_ids":["https://openalex.org/I4210100029","https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114039946","display_name":"Yiwen Lu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4391767661","display_name":"State Key Laboratory of Reproductive Medicine","ror":"https://ror.org/00cagf561","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yiwen Lu","raw_affiliation_strings":["State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China; Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China; Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]},{"raw_affiliation_string":"Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I83519826"]},{"raw_affiliation_string":"State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Mei Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4391767661","display_name":"State Key Laboratory of Reproductive Medicine","ror":"https://ror.org/00cagf561","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mei Li","raw_affiliation_strings":["State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China; Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China; Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]},{"raw_affiliation_string":"Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I83519826"]},{"raw_affiliation_string":"State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044411958","display_name":"Yijie Zhou","orcid":"https://orcid.org/0000-0003-0017-3107","observed_orcids":["https://orcid.org/0000-0003-0017-3107"]},"institutions":[{"id":"https://openalex.org/I4391767661","display_name":"State Key Laboratory of Reproductive Medicine","ror":"https://ror.org/00cagf561","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yijie Zhou","raw_affiliation_strings":["State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China; Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China; Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]},{"raw_affiliation_string":"Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I83519826"]},{"raw_affiliation_string":"State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003052042","display_name":"Peihao Wu","orcid":"https://orcid.org/0009-0005-6931-4790","observed_orcids":["https://orcid.org/0009-0005-6931-4790"]},"institutions":[{"id":"https://openalex.org/I4391767661","display_name":"State Key Laboratory of Reproductive Medicine","ror":"https://ror.org/00cagf561","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Peihao Wu","raw_affiliation_strings":["State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China; Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China; Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]},{"raw_affiliation_string":"Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I83519826"]},{"raw_affiliation_string":"State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100325433","display_name":"Jinhui Li","orcid":"https://orcid.org/0000-0002-2572-3454","observed_orcids":["https://orcid.org/0000-0002-2572-3454"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jinhui Li","raw_affiliation_strings":["Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0002-2572-3454","affiliations":[{"raw_affiliation_string":"Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, MA, USA","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100643724","display_name":"Feng Pan","orcid":"https://orcid.org/0000-0001-5164-9799","observed_orcids":["https://orcid.org/0000-0001-5164-9799"]},"institutions":[{"id":"https://openalex.org/I4210100029","display_name":"Nanjing Maternity and Child Health Care Hospital","ror":"https://ror.org/01a2gef28","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210100029"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Feng Pan","raw_affiliation_strings":["Department of Urology, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China","institution_ids":["https://openalex.org/I4210100029","https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019286556","display_name":"Xiumei Han","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4391767661","display_name":"State Key Laboratory of Reproductive Medicine","ror":"https://ror.org/00cagf561","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiumei Han","raw_affiliation_strings":["State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China; Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China; Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]},{"raw_affiliation_string":"Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I83519826"]},{"raw_affiliation_string":"State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055614782","display_name":"Minjian Chen","orcid":"https://orcid.org/0000-0002-5742-5080","observed_orcids":["https://orcid.org/0000-0002-5742-5080","https://orcid.org/0000-0002-2939-6518"]},"institutions":[{"id":"https://openalex.org/I4391767661","display_name":"State Key Laboratory of Reproductive Medicine","ror":"https://ror.org/00cagf561","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Minjian Chen","raw_affiliation_strings":["State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China; Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China"],"raw_orcid":"https://orcid.org/0000-0002-5742-5080","affiliations":[{"raw_affiliation_string":"State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China; Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]},{"raw_affiliation_string":"Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I83519826"]},{"raw_affiliation_string":"State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068107004","display_name":"Chuncheng Lu","orcid":"https://orcid.org/0000-0003-3689-9188","observed_orcids":["https://orcid.org/0000-0003-3689-9188","https://orcid.org/0000-0003-3742-0343"]},"institutions":[{"id":"https://openalex.org/I4391767661","display_name":"State Key Laboratory of Reproductive Medicine","ror":"https://ror.org/00cagf561","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chuncheng Lu","raw_affiliation_strings":["State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China; Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China"],"raw_orcid":"https://orcid.org/0000-0003-3689-9188","affiliations":[{"raw_affiliation_string":"State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China; Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]},{"raw_affiliation_string":"Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I83519826"]},{"raw_affiliation_string":"State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100599680","display_name":"Xinru Wang","orcid":"https://orcid.org/0000-0003-2636-9546","observed_orcids":["https://orcid.org/0000-0003-2636-9546","https://orcid.org/0009-0005-3542-0093"]},"institutions":[{"id":"https://openalex.org/I4391767661","display_name":"State Key Laboratory of Reproductive Medicine","ror":"https://ror.org/00cagf561","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinru Wang","raw_affiliation_strings":["State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China; Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China; Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]},{"raw_affiliation_string":"Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I83519826"]},{"raw_affiliation_string":"State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Wei Wu","orcid":"https://orcid.org/0000-0001-9110-9973","observed_orcids":["https://orcid.org/0000-0001-9110-9973"]},"institutions":[{"id":"https://openalex.org/I4391767661","display_name":"State Key Laboratory of Reproductive Medicine","ror":"https://ror.org/00cagf561","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Wei Wu","raw_affiliation_strings":["State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China; Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China. Electronic address: wwu@njmu.edu.cn","Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China"],"raw_orcid":"https://orcid.org/0000-0001-9110-9973","affiliations":[{"raw_affiliation_string":"State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China; Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China. Electronic address: wwu@njmu.edu.cn","institution_ids":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]},{"raw_affiliation_string":"Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I83519826"]},{"raw_affiliation_string":"State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5066824693","display_name":"Yankai Xia","orcid":"https://orcid.org/0000-0003-0484-4035","observed_orcids":["https://orcid.org/0000-0003-0484-4035"]},"institutions":[{"id":"https://openalex.org/I4391767661","display_name":"State Key Laboratory of Reproductive Medicine","ror":"https://ror.org/00cagf561","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yankai Xia","raw_affiliation_strings":["State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China; Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China; Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]},{"raw_affiliation_string":"Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I83519826"]},{"raw_affiliation_string":"State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China","institution_ids":["https://openalex.org/I4391767661","https://openalex.org/I83519826"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4391767661","https://openalex.org/I83519826"],"apc_list":{"value":3660,"currency":"USD","value_usd":3660},"apc_paid":{"value":3660,"currency":"USD","value_usd":3660},"fwci":8.2086,"has_fulltext":false,"cited_by_count":49,"citation_normalized_percentile":{"value":0.98529718,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"300","issue":null,"first_page":"118994","last_page":"118994"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.9624000191688538,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.9624000191688538,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10190","display_name":"Air Quality and Health Impacts","score":0.02410000003874302,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.003800000064074993,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/air-pollution","display_name":"air pollution","score":0.8529999852180481},{"id":"https://openalex.org/keywords/sperm-quality","display_name":"semen quality","score":0.9409999847412109},{"id":"https://openalex.org/keywords/sperm-dna-methylation","display_name":"sperm DNA methylation","score":0.9950000047683716},{"id":"https://openalex.org/keywords/5-hydroxymethylcytosine","display_name":"5-hydroxymethylcytosine","score":0.8840000033378601},{"id":"https://openalex.org/keywords/5-methylcytosine","display_name":"5-methylcytosine","score":0.9850000143051147},{"id":"https://openalex.org/keywords/pm10","display_name":"PM10","score":0.7979999780654907},{"id":"https://openalex.org/keywords/pm2-5","display_name":"PM2.5","score":1.0},{"id":"https://openalex.org/keywords/sulfur-dioxide","display_name":"sulfur dioxide","score":0.9909999966621399},{"id":"https://openalex.org/keywords/nitrogen-dioxide","display_name":"nitrogen dioxide","score":0.9890000224113464},{"id":"https://openalex.org/keywords/sperm-motility","display_name":"sperm motility","score":0.8920000195503235},{"id":"https://openalex.org/keywords/long-term-exposure","display_name":"long-term exposure","score":0.7820000052452087},{"id":"https://openalex.org/keywords/co-exposure","display_name":"combined exposure","score":0.7300000190734863},{"id":"https://openalex.org/keywords/male-fertility","display_name":"male fertility","score":0.6489999890327454},{"id":"https://openalex.org/keywords/weighted-quantile-sum-regression","display_name":"weighted quantile sum regression","score":0.8399999737739563}],"concepts":[{"id":"https://openalex.org/C2778080409","wikidata":"https://www.wikidata.org/wiki/Q2916689","display_name":"Semen quality","level":3,"score":0.8323357105255127},{"id":"https://openalex.org/C2778093475","wikidata":"https://www.wikidata.org/wiki/Q9715","display_name":"Semen","level":2,"score":0.7373395562171936},{"id":"https://openalex.org/C2781087480","wikidata":"https://www.wikidata.org/wiki/Q17145","display_name":"Sperm","level":2,"score":0.6387976408004761},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5396615862846375},{"id":"https://openalex.org/C2777632594","wikidata":"https://www.wikidata.org/wiki/Q27116486","display_name":"Sperm motility","level":3,"score":0.4769143760204315},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4637053608894348},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.35020869970321655},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.23302337527275085},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.13930931687355042},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.12041348218917847}],"mesh":[{"descriptor_ui":"D000393","descriptor_name":"Air Pollutants","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D000393","descriptor_name":"Air Pollutants","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D000397","descriptor_name":"Air Pollution","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013094","descriptor_name":"Spermatozoa","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D052638","descriptor_name":"Particulate Matter","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D055101","descriptor_name":"Semen Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.envpol.2022.118994","doi":"https://doi.org/10.1016/j.envpol.2022.118994","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.envpol.2022.118994","pdf_url":null,"source":{"id":"https://openalex.org/S201530359","display_name":"Environmental Pollution","issn_l":"0269-7491","issn":["0269-7491","1873-6424"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environmental Pollution","raw_type":"journal-article"},{"id":"pmid:35167929","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35167929","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environmental pollution (Barking, Essex : 1987)","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.envpol.2022.118994","doi":"https://doi.org/10.1016/j.envpol.2022.118994","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.envpol.2022.118994","pdf_url":null,"source":{"id":"https://openalex.org/S201530359","display_name":"Environmental Pollution","issn_l":"0269-7491","issn":["0269-7491","1873-6424"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environmental Pollution","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320327891","display_name":"Major Basic Research Project of the Natural Science Foundation of the Jiangsu Higher Education Institutions","ror":null},{"id":"https://openalex.org/F4320335774","display_name":"Key Technologies Research and Development Program","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":66,"referenced_works":["https://openalex.org/W1412161755","https://openalex.org/W1619621153","https://openalex.org/W1953060876","https://openalex.org/W1973632178","https://openalex.org/W2011652656","https://openalex.org/W2031443209","https://openalex.org/W2031625203","https://openalex.org/W2032042687","https://openalex.org/W2041282581","https://openalex.org/W2044202999","https://openalex.org/W2098406865","https://openalex.org/W2145625018","https://openalex.org/W2154280030","https://openalex.org/W2159902645","https://openalex.org/W2161852954","https://openalex.org/W2167306230","https://openalex.org/W2205050445","https://openalex.org/W2291679118","https://openalex.org/W2293032062","https://openalex.org/W2336537050","https://openalex.org/W2346964985","https://openalex.org/W2399730297","https://openalex.org/W2410299164","https://openalex.org/W2513644890","https://openalex.org/W2517448728","https://openalex.org/W2520842218","https://openalex.org/W2538474177","https://openalex.org/W2559922636","https://openalex.org/W2568616540","https://openalex.org/W2580365210","https://openalex.org/W2605052469","https://openalex.org/W2614290072","https://openalex.org/W2617398306","https://openalex.org/W2757939858","https://openalex.org/W2760883534","https://openalex.org/W2767909382","https://openalex.org/W2769314384","https://openalex.org/W2784262524","https://openalex.org/W2793830922","https://openalex.org/W2810064880","https://openalex.org/W2861401089","https://openalex.org/W2898769737","https://openalex.org/W2905280347","https://openalex.org/W2912582309","https://openalex.org/W2914189288","https://openalex.org/W2919054694","https://openalex.org/W2930344179","https://openalex.org/W2941876659","https://openalex.org/W2942318807","https://openalex.org/W2968802026","https://openalex.org/W2979482602","https://openalex.org/W2993308551","https://openalex.org/W3007787708","https://openalex.org/W3017664795","https://openalex.org/W3021971446","https://openalex.org/W3040925166","https://openalex.org/W3045318684","https://openalex.org/W3046650845","https://openalex.org/W3085485679","https://openalex.org/W3089409262","https://openalex.org/W3090655427","https://openalex.org/W3094448242","https://openalex.org/W3118291804","https://openalex.org/W3125422583","https://openalex.org/W3148381437","https://openalex.org/W6697000406"],"related_works":["https://openalex.org/W4385516074","https://openalex.org/W4413908686","https://openalex.org/W3094448242","https://openalex.org/W3033038591","https://openalex.org/W4220858608","https://openalex.org/W4410457459","https://openalex.org/W4318562469","https://openalex.org/W2513644890","https://openalex.org/W3201311938","https://openalex.org/W7167686697"],"abstract_inverted_index":{"Some":[0],"studies":[1],"have":[2],"examined":[3],"the":[4,19,28,36,67,115,129,147,159,204,214,227,230,288],"association":[5,116],"between":[6,117],"air":[7,24,32,55,119,232,279,293],"pollution":[8,25,33,56],"and":[9,104,122,152,165,271],"semen":[10,60,90,99,123,131,206,282],"quality.":[11,91,124],"While":[12],"it":[13,42],"is":[14],"less":[15],"of":[16,30,38,69,89,203,229,292],"evidence":[17],"on":[18],"sperm":[20,70,171,223,298],"quality":[21,132,207,283],"after":[22,226],"long-term":[23,52],"exposure,":[26],"especially":[27],"co-exposure":[29,121,228,276],"different":[31],"components.":[34],"Additionally,":[35],"role":[37],"DNA":[39,71,299],"methylation":[40,72],"in":[41,73,156,240,284],"hasn't":[43],"been":[44],"confirmed.":[45],"This":[46],"study":[47],"aimed":[48],"to":[49,54,65,78,85,113,145,267,277],"investigate":[50,114],"whether":[51],"exposure":[53,258,266,296],"was":[57,94,134,253],"associated":[58,169,255],"with":[59,170,211,256],"quality,":[61],"as":[62,64,96,273,275],"well":[63,274],"explore":[66],"effect":[68],"such":[74],"association.":[75],"From":[76],"2014":[77],"2016,":[79],"1607":[80],"fertile":[81,285],"men":[82],"were":[83,111,139,167,209],"enrolled":[84],"evaluate":[86],"14":[87],"parameters":[88],"Exposure":[92],"window":[93],"defined":[95],"one-year":[97],"before":[98],"sampling.":[100],"Multivariable":[101],"linear":[102],"regression":[103,109,218],"weighted":[105],"quantile":[106],"sum":[107],"(WQS)":[108],"model":[110],"used":[112],"six":[118,231,278],"pollutants":[120,233],"Sensitivity":[125],"analysis":[126],"regarding":[127],"at":[128],"normal":[130,205],"group":[133,208],"also":[135],"conducted.":[136],"Semen":[137],"samples":[138],"randomly":[140],"selected":[141],"from":[142,213],"200":[143],"participants":[144],"detect":[146],"genomic":[148],"5-methylcytosine":[149],"(5":[150],"mC)":[151],"5-hydroxymethylcytosine":[153],"(5-hmC)":[154],"levels":[155],"sperm.":[157],"In":[158],"total":[160,172,224],"population,":[161],"PM10,":[162,268],"PM2.5,":[163,269],"SO2,":[164,270],"NO2":[166],"negatively":[168],"motility":[173,225],"(PM10:":[174],"\u03b2":[175,182,189,196],"=":[176,179,183,186,190,193,197,200,235,238,260],"\u22122.67,":[177],"P":[178,185,192,199,237,262],"0.009;":[180],"PM2.5:":[181],"\u22122.86,":[184],"0.004;":[187],"SO2:":[188],"\u22122.32,":[191],"0.011;":[194],"NO2:":[195],"\u22122.21,":[198],"0.012).":[201],"Results":[202],"consistent":[210],"those":[212],"whole":[215,241],"population.":[216],"WQS":[217],"results":[219],"indicated":[220],"significant":[221,290],"decreasing":[222],"(\u03b2":[234,259],"\u22121.64,":[236],"0.003)":[239],"participants.":[242],"Wherein,":[243],"PM10":[244,257,295],"accounted":[245],"for":[246],"largest":[247],"proportion":[248],"(43.4%).":[249],"The":[250],"5-hmC":[251],"level":[252],"positively":[254],"0.002,":[261],"<":[263],"0.001).":[264],"Long-term":[265],"NO2,":[272],"pollutants,":[280],"reduced":[281],"men.":[286],"As":[287],"most":[289],"contributor":[291],"pollutant,":[294],"decreased":[297],"methylation.":[300]},"counts_by_year":[{"year":2026,"cited_by_count":10},{"year":2025,"cited_by_count":13},{"year":2024,"cited_by_count":12},{"year":2023,"cited_by_count":13},{"year":2022,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2022-02-13T00:00:00"}