{"id":"https://openalex.org/W4210683406","doi":"https://doi.org/10.1039/d1nr06074k","title":"Electrical and thermal stimulus-responsive nanocarbon-based 3D hydrogel sponge for switchable drug delivery","display_name":"Electrical and thermal stimulus-responsive nanocarbon-based 3D hydrogel sponge for switchable drug delivery","publication_year":2022,"publication_date":"2022-01-01","ids":{"openalex":"https://openalex.org/W4210683406","doi":"https://doi.org/10.1039/d1nr06074k","pmid":"https://pubmed.ncbi.nlm.nih.gov/35088797"},"language":"en","primary_location":{"id":"doi:10.1039/d1nr06074k","doi":"https://doi.org/10.1039/d1nr06074k","is_oa":false,"landing_page_url":"https://doi.org/10.1039/d1nr06074k","pdf_url":null,"source":{"id":"https://openalex.org/S23181512","display_name":"Nanoscale","issn_l":"2040-3364","issn":["2040-3364","2040-3372"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanoscale","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040511617","display_name":"Sang-Yu Park","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405258472","display_name":"Korea Carbon Industry Promotion Agency","ror":"https://ror.org/00qbxky68","country_code":"KR","type":"facility","lineage":["https://openalex.org/I2801339556","https://openalex.org/I4210089395","https://openalex.org/I4405258472"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Sang-Yu Park","raw_affiliation_strings":["Innovative Carbon-Bio-Convergence Lab., Korea Carbon Industry Promotion Agency (kcarbon), 110-11 Ballyong-ro, Deokjin-gu, Jeonju 54853, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Innovative Carbon-Bio-Convergence Lab., Korea Carbon Industry Promotion Agency (kcarbon), 110-11 Ballyong-ro, Deokjin-gu, Jeonju 54853, Republic of Korea","institution_ids":["https://openalex.org/I4405258472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101189057","display_name":"Ji-Hye Kang","orcid":"https://orcid.org/0009-0007-0404-1626","observed_orcids":["https://orcid.org/0009-0007-0404-1626"]},"institutions":[{"id":"https://openalex.org/I89015989","display_name":"Dankook University","ror":"https://ror.org/058pdbn81","country_code":"KR","type":"education","lineage":["https://openalex.org/I89015989"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Ji-Hye Kang","raw_affiliation_strings":["Department of Nanobiomedical Science, BK21 FOUR NBM Global Research Center for Regenerative Medicine, Dankook University, 119 Dandae-ro, Dongnam-gu, Cheonan 31116, Republic of Korea","Institute of Tissue Regeneration Engineering (ITREN), Dankook University, 119 Dandae-ro, Dongnam-gu, Cheonan 31116, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nanobiomedical Science, BK21 FOUR NBM Global Research Center for Regenerative Medicine, Dankook University, 119 Dandae-ro, Dongnam-gu, Cheonan 31116, Republic of Korea","institution_ids":["https://openalex.org/I89015989"]},{"raw_affiliation_string":"Institute of Tissue Regeneration Engineering (ITREN), Dankook University, 119 Dandae-ro, Dongnam-gu, Cheonan 31116, Republic of Korea","institution_ids":["https://openalex.org/I89015989"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045842792","display_name":"Han\u2010Sem Kim","orcid":"https://orcid.org/0000-0002-0050-8811","observed_orcids":["https://orcid.org/0000-0002-0050-8811"]},"institutions":[{"id":"https://openalex.org/I89015989","display_name":"Dankook University","ror":"https://ror.org/058pdbn81","country_code":"KR","type":"education","lineage":["https://openalex.org/I89015989"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Han-Sem Kim","raw_affiliation_strings":["Institute of Tissue Regeneration Engineering (ITREN), Dankook University, 119 Dandae-ro, Dongnam-gu, Cheonan 31116, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Tissue Regeneration Engineering (ITREN), Dankook University, 119 Dandae-ro, Dongnam-gu, Cheonan 31116, Republic of Korea","institution_ids":["https://openalex.org/I89015989"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019637670","display_name":"Ji\u2010Young Hwang","orcid":"https://orcid.org/0000-0001-8044-1989","observed_orcids":["https://orcid.org/0000-0001-8044-1989"]},"institutions":[{"id":"https://openalex.org/I4405258472","display_name":"Korea Carbon Industry Promotion Agency","ror":"https://ror.org/00qbxky68","country_code":"KR","type":"facility","lineage":["https://openalex.org/I2801339556","https://openalex.org/I4210089395","https://openalex.org/I4405258472"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Ji-Young Hwang","raw_affiliation_strings":["Innovative Carbon-Bio-Convergence Lab., Korea Carbon Industry Promotion Agency (kcarbon), 110-11 Ballyong-ro, Deokjin-gu, Jeonju 54853, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0001-8044-1989","affiliations":[{"raw_affiliation_string":"Innovative Carbon-Bio-Convergence Lab., Korea Carbon Industry Promotion Agency (kcarbon), 110-11 Ballyong-ro, Deokjin-gu, Jeonju 54853, Republic of Korea","institution_ids":["https://openalex.org/I4405258472"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031492701","display_name":"Ueon Sang Shin","orcid":"https://orcid.org/0000-0003-1648-863X","observed_orcids":["https://orcid.org/0000-0003-1648-863X"]},"institutions":[{"id":"https://openalex.org/I89015989","display_name":"Dankook University","ror":"https://ror.org/058pdbn81","country_code":"KR","type":"education","lineage":["https://openalex.org/I89015989"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Ueon Sang Shin","raw_affiliation_strings":["Department of Nanobiomedical Science, BK21 FOUR NBM Global Research Center for Regenerative Medicine, Dankook University, 119 Dandae-ro, Dongnam-gu, Cheonan 31116, Republic of Korea","Institute of Tissue Regeneration Engineering (ITREN), Dankook University, 119 Dandae-ro, Dongnam-gu, Cheonan 31116, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nanobiomedical Science, BK21 FOUR NBM Global Research Center for Regenerative Medicine, Dankook University, 119 Dandae-ro, Dongnam-gu, Cheonan 31116, Republic of Korea","institution_ids":["https://openalex.org/I89015989"]},{"raw_affiliation_string":"Institute of Tissue Regeneration Engineering (ITREN), Dankook University, 119 Dandae-ro, Dongnam-gu, Cheonan 31116, Republic of Korea","institution_ids":["https://openalex.org/I89015989"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5019637670","https://openalex.org/A5031492701"],"corresponding_institution_ids":["https://openalex.org/I4405258472","https://openalex.org/I89015989"],"apc_list":null,"apc_paid":null,"fwci":2.3133,"has_fulltext":false,"cited_by_count":47,"citation_normalized_percentile":{"value":0.89582903,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"14","issue":"6","first_page":"2367","last_page":"2382"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11737","display_name":"Advanced Materials and Mechanics","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2210","display_name":"Mechanical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10729","display_name":"Electrospun Nanofibers in Biomedical Applications","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/carbon-nanotubes","display_name":"carbon nanotubes","score":0.7730000019073486},{"id":"https://openalex.org/keywords/chitosan","display_name":"chitosan","score":0.8169999718666077},{"id":"https://openalex.org/keywords/ketoprofen","display_name":"ketoprofen","score":0.7039999961853027},{"id":"https://openalex.org/keywords/transdermal-drug-delivery","display_name":"transdermal drug delivery","score":0.9490000009536743},{"id":"https://openalex.org/keywords/smart-drug-carriers","display_name":"smart drug carriers","score":0.45500001311302185},{"id":"https://openalex.org/keywords/musculoskeletal-pain","display_name":"musculoskeletal pain","score":0.675000011920929}],"concepts":[{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.7843401432037354},{"id":"https://openalex.org/C108586683","wikidata":"https://www.wikidata.org/wiki/Q17164826","display_name":"Self-healing hydrogels","level":2,"score":0.6731756925582886},{"id":"https://openalex.org/C2779820397","wikidata":"https://www.wikidata.org/wiki/Q1392806","display_name":"Drug delivery","level":2,"score":0.6583123803138733},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.5691241025924683},{"id":"https://openalex.org/C513720949","wikidata":"https://www.wikidata.org/wiki/Q1778729","display_name":"Carbon nanotube","level":2,"score":0.4978811740875244},{"id":"https://openalex.org/C205679159","wikidata":"https://www.wikidata.org/wiki/Q3375179","display_name":"Transdermal","level":2,"score":0.4742495119571686},{"id":"https://openalex.org/C138631740","wikidata":"https://www.wikidata.org/wiki/Q967847","display_name":"Nanomaterials","level":2,"score":0.4265616238117218},{"id":"https://openalex.org/C188027245","wikidata":"https://www.wikidata.org/wiki/Q750446","display_name":"Polymer chemistry","level":1,"score":0.10502409934997559},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D004553","descriptor_name":"Electric Conductivity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011108","descriptor_name":"Polymers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020100","descriptor_name":"Hydrogels","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D037742","descriptor_name":"Nanotubes, Carbon","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D048271","descriptor_name":"Chitosan","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1039/d1nr06074k","doi":"https://doi.org/10.1039/d1nr06074k","is_oa":false,"landing_page_url":"https://doi.org/10.1039/d1nr06074k","pdf_url":null,"source":{"id":"https://openalex.org/S23181512","display_name":"Nanoscale","issn_l":"2040-3364","issn":["2040-3364","2040-3372"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanoscale","raw_type":"journal-article"},{"id":"pmid:35088797","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35088797","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanoscale","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6240000128746033}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1813229387","display_name":null,"funder_award_id":"NRF-2020R1F1A1072210","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G2270010005","display_name":null,"funder_award_id":"NRF-2018R1D1A1B07048222","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G7261036014","display_name":null,"funder_award_id":"NRF-2019R1A6A1A11034536","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"}],"funders":[{"id":"https://openalex.org/F4320322120","display_name":"National Research Foundation of Korea","ror":"https://ror.org/013aysd81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":49,"referenced_works":["https://openalex.org/W1971437367","https://openalex.org/W1977770258","https://openalex.org/W1979577269","https://openalex.org/W1994876310","https://openalex.org/W2018339166","https://openalex.org/W2030857859","https://openalex.org/W2033034456","https://openalex.org/W2056925688","https://openalex.org/W2080430067","https://openalex.org/W2083457177","https://openalex.org/W2085076666","https://openalex.org/W2097746483","https://openalex.org/W2120504559","https://openalex.org/W2135244646","https://openalex.org/W2290287807","https://openalex.org/W2315301350","https://openalex.org/W2331185561","https://openalex.org/W2355475704","https://openalex.org/W2410211206","https://openalex.org/W2417266590","https://openalex.org/W2527569309","https://openalex.org/W2541710294","https://openalex.org/W2580420606","https://openalex.org/W2595595356","https://openalex.org/W2605397222","https://openalex.org/W2621435552","https://openalex.org/W2751165972","https://openalex.org/W2770487735","https://openalex.org/W2770692750","https://openalex.org/W2782980850","https://openalex.org/W2785382519","https://openalex.org/W2791036738","https://openalex.org/W2797451760","https://openalex.org/W2888584035","https://openalex.org/W2892572292","https://openalex.org/W2898078567","https://openalex.org/W2903438236","https://openalex.org/W2907868307","https://openalex.org/W2909542524","https://openalex.org/W2915542701","https://openalex.org/W2919684530","https://openalex.org/W2921304587","https://openalex.org/W2921572350","https://openalex.org/W2943993988","https://openalex.org/W2969869780","https://openalex.org/W3087442809","https://openalex.org/W3179063978","https://openalex.org/W3193451237","https://openalex.org/W4211147424"],"related_works":["https://openalex.org/W4286214328","https://openalex.org/W6911833849","https://openalex.org/W2803587176","https://openalex.org/W3037978001","https://openalex.org/W3007441014","https://openalex.org/W2040473125","https://openalex.org/W3021508676","https://openalex.org/W3103488210","https://openalex.org/W2260997576","https://openalex.org/W3216146054"],"abstract_inverted_index":{"-BBVIm)":[0],"(pNIBBIm)":[1],"as":[2],"the":[3,12,29,38,42,56,73],"drug":[4,83,116],"carrier":[5],"and":[6,14,17,25,67,71,91,104,114,122],"a":[7,19,51,80],"temperature-responsive":[8],"copolymer.":[9],"By":[10],"formulating":[11],"CNT-core":[13],"Chit-shell":[15],"units":[16],"constructing":[18],"CNT":[20,39],"sponge":[21],"framework,":[22],"uniform":[23],"distribution":[24],"3D":[26,34,43,97],"connectivity":[27],"of":[28,50,58,94,109],"CNTs":[30],"were":[31],"improved.":[32],"The":[33,86],"hydrogel":[35,99],"based":[36],"on":[37],"sponge,":[40],"namely":[41],"frame":[44,98],"CNT-Chit/pNIBBIm":[45],"hydrogel,":[46],"delivered":[47],"approximately":[48],"37%":[49],"drug,":[52],"ketoprofen":[53],"used":[54],"for":[55,76,119],"treatment":[57],"musculoskeletal":[59],"pain,":[60],"during":[61],"about":[62],"30%":[63],"shrinkage":[64],"after":[65],"electrical":[66,103],"thermal":[68,105],"switches":[69],"on/off":[70],"exhibited":[72],"best":[74],"potential":[75],"future":[77],"use":[78],"in":[79],"smart":[81],"transdermal":[82],"delivery":[84,117],"system.":[85],"physicochemical,":[87],"mechanical,":[88],"electrical,":[89],"thermal,":[90],"biocompatible":[92],"characteristics":[93],"this":[95],"nanocarbon-based":[96],"led":[100],"to":[101],"remarkable":[102],"stimulus-responsive":[106],"properties":[107],"capable":[108],"developing":[110],"an":[111],"excellent":[112],"controllable":[113],"switchable":[115],"platform":[118],"biomedical":[120],"engineering":[121],"medicine":[123],"applications.":[124]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":16},{"year":2022,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2022-02-08T00:00:00"}
