{"id":"https://openalex.org/W4206752174","doi":"https://doi.org/10.1111/andr.13158","title":"Supplementation of Mito TEMPO and acetovanillone in semen extender improves freezability of buffalo spermatozoa","display_name":"Supplementation of Mito TEMPO and acetovanillone in semen extender improves freezability of buffalo spermatozoa","publication_year":2022,"publication_date":"2022-01-21","ids":{"openalex":"https://openalex.org/W4206752174","doi":"https://doi.org/10.1111/andr.13158","pmid":"https://pubmed.ncbi.nlm.nih.gov/35060362"},"language":"en","primary_location":{"id":"doi:10.1111/andr.13158","doi":"https://doi.org/10.1111/andr.13158","is_oa":true,"landing_page_url":"https://doi.org/10.1111/andr.13158","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/andr.13158","source":{"id":"https://openalex.org/S90729755","display_name":"Andrology","issn_l":"2047-2919","issn":["2047-2919","2047-2927"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Andrology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/andr.13158","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100403749","display_name":"Abhishek Kumar","orcid":"https://orcid.org/0000-0003-4247-9390","observed_orcids":["https://orcid.org/0000-0003-4247-9390"]},"institutions":[{"id":"https://openalex.org/I185790649","display_name":"Indian Veterinary Research Institute","ror":"https://ror.org/02jcfzc36","country_code":"IN","type":"facility","lineage":["https://openalex.org/I179420787","https://openalex.org/I185790649"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Abhishek Kumar","raw_affiliation_strings":["Division of Animal Reproduction, ICAR-Indian Veterinary Research Institute, Bareilly, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Animal Reproduction, ICAR-Indian Veterinary Research Institute, Bareilly, India","institution_ids":["https://openalex.org/I185790649"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101557197","display_name":"Subrata Kumar Ghosh","orcid":"https://orcid.org/0000-0003-1337-475X","observed_orcids":["https://orcid.org/0000-0003-1337-475X"]},"institutions":[{"id":"https://openalex.org/I185790649","display_name":"Indian Veterinary Research Institute","ror":"https://ror.org/02jcfzc36","country_code":"IN","type":"facility","lineage":["https://openalex.org/I179420787","https://openalex.org/I185790649"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Subrata Kumar Ghosh","raw_affiliation_strings":["Division of Animal Reproduction, ICAR-Indian Veterinary Research Institute, Bareilly, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Animal Reproduction, ICAR-Indian Veterinary Research Institute, Bareilly, India","institution_ids":["https://openalex.org/I185790649"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052812590","display_name":"Rahul Katiyar","orcid":"https://orcid.org/0000-0002-0830-3837","observed_orcids":["https://orcid.org/0000-0002-0830-3837"]},"institutions":[{"id":"https://openalex.org/I185790649","display_name":"Indian Veterinary Research Institute","ror":"https://ror.org/02jcfzc36","country_code":"IN","type":"facility","lineage":["https://openalex.org/I179420787","https://openalex.org/I185790649"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Rahul Katiyar","raw_affiliation_strings":["Division of Animal Reproduction, ICAR-Indian Veterinary Research Institute, Bareilly, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Animal Reproduction, ICAR-Indian Veterinary Research Institute, Bareilly, India","institution_ids":["https://openalex.org/I185790649"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045355219","display_name":"Amare Eshetu Gemeda","orcid":"https://orcid.org/0000-0003-0762-0221","observed_orcids":["https://orcid.org/0000-0003-0762-0221"]},"institutions":[{"id":"https://openalex.org/I185790649","display_name":"Indian Veterinary Research Institute","ror":"https://ror.org/02jcfzc36","country_code":"IN","type":"facility","lineage":["https://openalex.org/I179420787","https://openalex.org/I185790649"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Amare Eshetu Gemeda","raw_affiliation_strings":["Division of Animal Reproduction, ICAR-Indian Veterinary Research Institute, Bareilly, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Animal Reproduction, ICAR-Indian Veterinary Research Institute, Bareilly, India","institution_ids":["https://openalex.org/I185790649"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061399592","display_name":"Rupali Rautela","orcid":"https://orcid.org/0000-0003-2590-7955","observed_orcids":["https://orcid.org/0000-0003-2590-7955"]},"institutions":[{"id":"https://openalex.org/I185790649","display_name":"Indian Veterinary Research Institute","ror":"https://ror.org/02jcfzc36","country_code":"IN","type":"facility","lineage":["https://openalex.org/I179420787","https://openalex.org/I185790649"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Rupali Rautela","raw_affiliation_strings":["Division of Animal Reproduction, ICAR-Indian Veterinary Research Institute, Bareilly, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Animal Reproduction, ICAR-Indian Veterinary Research Institute, Bareilly, India","institution_ids":["https://openalex.org/I185790649"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049245897","display_name":"Amarjeet Bisla","orcid":"https://orcid.org/0000-0002-4468-0146","observed_orcids":["https://orcid.org/0000-0002-4468-0146"]},"institutions":[{"id":"https://openalex.org/I185790649","display_name":"Indian Veterinary Research Institute","ror":"https://ror.org/02jcfzc36","country_code":"IN","type":"facility","lineage":["https://openalex.org/I179420787","https://openalex.org/I185790649"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Amarjeet Bisla","raw_affiliation_strings":["Division of Animal Reproduction, ICAR-Indian Veterinary Research Institute, Bareilly, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Animal Reproduction, ICAR-Indian Veterinary Research Institute, Bareilly, India","institution_ids":["https://openalex.org/I185790649"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018904399","display_name":"Neeraj Srivastava","orcid":"https://orcid.org/0000-0002-9559-6139","observed_orcids":["https://orcid.org/0000-0002-9559-6139"]},"institutions":[{"id":"https://openalex.org/I185790649","display_name":"Indian Veterinary Research Institute","ror":"https://ror.org/02jcfzc36","country_code":"IN","type":"facility","lineage":["https://openalex.org/I179420787","https://openalex.org/I185790649"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Neeraj Srivastava","raw_affiliation_strings":["Division of Animal Reproduction, ICAR-Indian Veterinary Research Institute, Bareilly, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Animal Reproduction, ICAR-Indian Veterinary Research Institute, Bareilly, India","institution_ids":["https://openalex.org/I185790649"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108457774","display_name":"Sanjeev Kumar Bhure","orcid":"https://orcid.org/0000-0002-0209-0287","observed_orcids":["https://orcid.org/0000-0002-0209-0287"]},"institutions":[{"id":"https://openalex.org/I179420787","display_name":"Indian Council of Agricultural Research","ror":"https://ror.org/04fw54a43","country_code":"IN","type":"government","lineage":["https://openalex.org/I179420787"]},{"id":"https://openalex.org/I185790649","display_name":"Indian Veterinary Research Institute","ror":"https://ror.org/02jcfzc36","country_code":"IN","type":"facility","lineage":["https://openalex.org/I179420787","https://openalex.org/I185790649"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Sanjeev Kumar Bhure","raw_affiliation_strings":["Division of Biochemistry, ICAR-Indian Veterinary Research Institute, Bareilly, India"],"raw_orcid":"https://orcid.org/0000-0002-0209-0287","affiliations":[{"raw_affiliation_string":"Division of Biochemistry, ICAR-Indian Veterinary Research Institute, Bareilly, India","institution_ids":["https://openalex.org/I179420787","https://openalex.org/I185790649"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063160025","display_name":"Huidrom Lakshmi Devi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185790649","display_name":"Indian Veterinary Research Institute","ror":"https://ror.org/02jcfzc36","country_code":"IN","type":"facility","lineage":["https://openalex.org/I179420787","https://openalex.org/I185790649"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Huidrom Lakshmi Devi","raw_affiliation_strings":["Division of Physiology & Climatology ICAR\u2010Indian Veterinary Research Institute Bareilly India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Physiology & Climatology ICAR\u2010Indian Veterinary Research Institute Bareilly India","institution_ids":["https://openalex.org/I185790649"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027807399","display_name":"Vikash Chandra","orcid":"https://orcid.org/0000-0002-2142-3024","observed_orcids":["https://orcid.org/0000-0002-2142-3024"]},"institutions":[{"id":"https://openalex.org/I185790649","display_name":"Indian Veterinary Research Institute","ror":"https://ror.org/02jcfzc36","country_code":"IN","type":"facility","lineage":["https://openalex.org/I179420787","https://openalex.org/I185790649"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Vikash Chandra","raw_affiliation_strings":["Division of Physiology & Climatology ICAR\u2010Indian Veterinary Research Institute Bareilly India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Physiology & Climatology ICAR\u2010Indian Veterinary Research Institute Bareilly India","institution_ids":["https://openalex.org/I185790649"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5101557197"],"corresponding_institution_ids":["https://openalex.org/I185790649"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":3.3094,"has_fulltext":true,"cited_by_count":29,"citation_normalized_percentile":{"value":0.92880217,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"10","issue":"4","first_page":"775","last_page":"788"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10584","display_name":"Reproductive Physiology in Livestock","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/buffalo-semen","display_name":"buffalo semen","score":0.48399999737739563},{"id":"https://openalex.org/keywords/sperm-cryopreservation","display_name":"sperm cryopreservation","score":0.8349999785423279},{"id":"https://openalex.org/keywords/mitotempo","display_name":"MitoTEMPO","score":0.8930000066757202},{"id":"https://openalex.org/keywords/apocynin","display_name":"apocynin","score":0.9980000257492065},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.734000027179718},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.9559999704360962},{"id":"https://openalex.org/keywords/semen-extender-supplementation","display_name":"semen extender supplementation","score":0.753000020980835},{"id":"https://openalex.org/keywords/post-thaw-sperm-quality","display_name":"post-thaw sperm quality","score":0.8799999952316284},{"id":"https://openalex.org/keywords/mitochondrial-membrane-potential","display_name":"mitochondrial membrane potential","score":0.7200000286102295},{"id":"https://openalex.org/keywords/lipid-peroxidation","display_name":"lipid peroxidation","score":0.8970000147819519},{"id":"https://openalex.org/keywords/plasma-membrane-integrity","display_name":"plasma membrane integrity","score":0.8059999942779541},{"id":"https://openalex.org/keywords/sperm-capacitation","display_name":"sperm capacitation","score":0.6100000143051147},{"id":"https://openalex.org/keywords/antioxidants","display_name":"antioxidants","score":0.527999997138977},{"id":"https://openalex.org/keywords/cholesterol-to-phospholipid-ratio","display_name":"cholesterol/phospholipid ratio","score":0.7730000019073486},{"id":"https://openalex.org/keywords/sperm-motility","display_name":"sperm motility","score":0.5490000247955322}],"concepts":[{"id":"https://openalex.org/C2778093475","wikidata":"https://www.wikidata.org/wiki/Q9715","display_name":"Semen","level":2,"score":0.7812700271606445},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7677819728851318},{"id":"https://openalex.org/C2776586616","wikidata":"https://www.wikidata.org/wiki/Q5421909","display_name":"Extender","level":3,"score":0.7652592658996582},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.6901323795318604},{"id":"https://openalex.org/C2779700439","wikidata":"https://www.wikidata.org/wiki/Q7449211","display_name":"Semen extender","level":4,"score":0.6198093295097351},{"id":"https://openalex.org/C2778080409","wikidata":"https://www.wikidata.org/wiki/Q2916689","display_name":"Semen quality","level":3,"score":0.6050271987915039},{"id":"https://openalex.org/C2780829032","wikidata":"https://www.wikidata.org/wiki/Q898539","display_name":"Lipid peroxidation","level":3,"score":0.6037091612815857},{"id":"https://openalex.org/C2781087480","wikidata":"https://www.wikidata.org/wiki/Q17145","display_name":"Sperm","level":2,"score":0.503574788570404},{"id":"https://openalex.org/C48349386","wikidata":"https://www.wikidata.org/wiki/Q424361","display_name":"Reactive oxygen species","level":2,"score":0.4949283003807068},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.47880062460899353},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.47273197770118713},{"id":"https://openalex.org/C2780301668","wikidata":"https://www.wikidata.org/wiki/Q1728362","display_name":"Capacitation","level":3,"score":0.46722137928009033},{"id":"https://openalex.org/C2994365204","wikidata":"https://www.wikidata.org/wiki/Q29548","display_name":"Membrane integrity","level":3,"score":0.4246487021446228},{"id":"https://openalex.org/C2777632594","wikidata":"https://www.wikidata.org/wiki/Q27116486","display_name":"Sperm motility","level":3,"score":0.42236411571502686},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3196049928665161},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.27122098207473755},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.22767451405525208},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C2779578285","wikidata":"https://www.wikidata.org/wiki/Q146322","display_name":"Polyurethane","level":2,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000098","descriptor_name":"Acetophenones","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002020","descriptor_name":"Buffaloes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003451","descriptor_name":"Cryoprotective Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D003497","descriptor_name":"Cyclic N-Oxides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012661","descriptor_name":"Semen","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012662","descriptor_name":"Semen Preservation","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":true},{"descriptor_ui":"D013081","descriptor_name":"Sperm Motility","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013094","descriptor_name":"Spermatozoa","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015925","descriptor_name":"Cryopreservation","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D017382","descriptor_name":"Reactive Oxygen Species","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019587","descriptor_name":"Dietary Supplements","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055101","descriptor_name":"Semen Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/andr.13158","doi":"https://doi.org/10.1111/andr.13158","is_oa":true,"landing_page_url":"https://doi.org/10.1111/andr.13158","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/andr.13158","source":{"id":"https://openalex.org/S90729755","display_name":"Andrology","issn_l":"2047-2919","issn":["2047-2919","2047-2927"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Andrology","raw_type":"journal-article"},{"id":"pmid:35060362","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35060362","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Andrology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1111/andr.13158","doi":"https://doi.org/10.1111/andr.13158","is_oa":true,"landing_page_url":"https://doi.org/10.1111/andr.13158","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/andr.13158","source":{"id":"https://openalex.org/S90729755","display_name":"Andrology","issn_l":"2047-2919","issn":["2047-2919","2047-2927"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Andrology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.5683000087738037}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320769","display_name":"Indian Council of Agricultural Research","ror":"https://ror.org/04fw54a43"},{"id":"https://openalex.org/F4320326602","display_name":"ICAR-Indian Veterinary Research Institute","ror":"https://ror.org/02jcfzc36"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4206752174.pdf","grobid_xml":"https://content.openalex.org/works/W4206752174.grobid-xml"},"referenced_works_count":80,"referenced_works":["https://openalex.org/W121565118","https://openalex.org/W205594055","https://openalex.org/W248280472","https://openalex.org/W752686105","https://openalex.org/W1512037315","https://openalex.org/W1513897103","https://openalex.org/W1517256995","https://openalex.org/W1532388834","https://openalex.org/W1590457525","https://openalex.org/W1905740399","https://openalex.org/W1975688735","https://openalex.org/W1978693303","https://openalex.org/W1991734190","https://openalex.org/W1995782034","https://openalex.org/W1998059695","https://openalex.org/W1998376527","https://openalex.org/W1999099572","https://openalex.org/W1999875017","https://openalex.org/W2002709823","https://openalex.org/W2007585501","https://openalex.org/W2008991892","https://openalex.org/W2010433725","https://openalex.org/W2024542193","https://openalex.org/W2026172978","https://openalex.org/W2027319991","https://openalex.org/W2030883169","https://openalex.org/W2031759290","https://openalex.org/W2039285124","https://openalex.org/W2059357839","https://openalex.org/W2068052959","https://openalex.org/W2072526865","https://openalex.org/W2073241455","https://openalex.org/W2076896164","https://openalex.org/W2087220465","https://openalex.org/W2090537099","https://openalex.org/W2095954713","https://openalex.org/W2098501095","https://openalex.org/W2104328439","https://openalex.org/W2112164869","https://openalex.org/W2115054403","https://openalex.org/W2115334331","https://openalex.org/W2118583516","https://openalex.org/W2125943091","https://openalex.org/W2138582747","https://openalex.org/W2139559523","https://openalex.org/W2140014506","https://openalex.org/W2144153570","https://openalex.org/W2147915070","https://openalex.org/W2148694161","https://openalex.org/W2158173525","https://openalex.org/W2162294047","https://openalex.org/W2165292984","https://openalex.org/W2288838295","https://openalex.org/W2295386248","https://openalex.org/W2398590379","https://openalex.org/W2489700573","https://openalex.org/W2768568484","https://openalex.org/W2777135095","https://openalex.org/W2810372309","https://openalex.org/W2883677399","https://openalex.org/W2887948492","https://openalex.org/W2888762512","https://openalex.org/W2899457333","https://openalex.org/W2942599542","https://openalex.org/W2966674062","https://openalex.org/W2969327403","https://openalex.org/W2987624206","https://openalex.org/W3016682302","https://openalex.org/W3016968385","https://openalex.org/W3042915496","https://openalex.org/W3092181076","https://openalex.org/W3097376324","https://openalex.org/W3112906146","https://openalex.org/W3131569371","https://openalex.org/W3152582975","https://openalex.org/W3160562726","https://openalex.org/W3163191296","https://openalex.org/W3170852019","https://openalex.org/W3173634421","https://openalex.org/W6630788313"],"related_works":["https://openalex.org/W3160562726","https://openalex.org/W3112906146","https://openalex.org/W4411799341","https://openalex.org/W3198674722","https://openalex.org/W4387335692","https://openalex.org/W2777135095","https://openalex.org/W3211084362","https://openalex.org/W7127969583","https://openalex.org/W2103290680","https://openalex.org/W3094553834"],"abstract_inverted_index":{"BACKGROUND:":[0],"Oxidative":[1],"stress":[2],"is":[3],"one":[4],"of":[5,16,18,47,54,63,83,94,118,149,157,168,208,232,255,274,319,333,360,362,383,399,406,415,431,440,442],"the":[6,45,58,81,101,162,177,294,312,330,426,457],"leading":[7],"factors":[8],"responsible":[9],"for":[10,52,71,161,184,460],"poor":[11],"post-thaw":[12,205,250,341,462],"semen":[13,103,251,342,463],"quality":[14,252,343],"because":[15,359],"overproduction":[17],"reactive":[19],"oxygen":[20],"species":[21],"(ROS)":[22],"over":[23],"neutralizing":[24],"antioxidants":[25],"present":[26,35],"in":[27,36,90,219,243,253,317,344,352,387,424],"semen.":[28],"Mainly":[29],"two":[30],"ROS":[31,55,283,321],"generation":[32],"sites":[33,51],"are":[34],"spermatozoa,":[37,276],"that":[38,328],"is,":[39],"mitochondria":[40,313],"and":[41,86,89,115,133,171,195,204,218,237,242,270,287,306,323,392,402,428,445,450],"plasma":[42,186,257,433],"membrane.":[43,434],"Therefore,":[44],"idea":[46],"targeting":[48],"these":[49],"specific":[50],"minimization":[53],"production":[56,322],"with":[57,107,152],"compounds":[59],"having":[60],"known":[61],"mechanism":[62],"actions":[64],"was":[65,77,105,142,453],"built":[66],"up":[67],"as":[68,128,144,175,291,302,369,454,456],"a":[69,116,421],"core":[70],"this":[72,370],"research.":[73],"OBJECTIVE:":[74],"Present":[75],"study":[76],"done":[78,174],"to":[79,197,293,381],"investigate":[80],"effects":[82,439],"Mito":[84,108,119,233,299,443],"TEMPO":[85,109,120,234,300,444],"acetovanillone":[87,112,122,238,353,446],"individually":[88,241],"combination":[91,117,244,458],"on":[92,226,447],"freezability":[93,449],"buffalo":[95,275],"spermatozoa.":[96],"MATERIALS":[97],"AND":[98],"METHODS:":[99],"For":[100],"experiment,":[102],"extender":[104],"supplemented":[106,347],"(50":[110,113,123,235,239,354],"\u03bcM),":[111,114,126],"+":[121],"\u03bcM+":[124],"50":[125,345],"designated":[127,143],"Group":[129,131,134,145],"II,":[130],"III,":[132],"IV,":[135],"respectively.":[136],"Control":[137],"group":[138,356,459],"without":[139],"any":[140],"supplementation":[141,441,452],"I.":[146],"A":[147],"total":[148,191],"24":[150],"ejaculates":[151],"individual":[153,451],"progressive":[154],"motility":[155],"(IPM)":[156],"\u226570%":[158],"were":[159,173,182,223],"selected":[160],"study.":[163],"After":[164],"final":[165],"dilution,":[166],"filling-sealing":[167],"straws,":[169],"equilibration,":[170],"freezing":[172],"per":[176],"standard":[178],"procedure.":[179],"Semen":[180],"samples":[181],"evaluated":[183],"IPM,":[185,256],"membrane":[187,211,258],"integrity,":[188,259],"lipid":[189,285],"peroxidation,":[190,286],"antioxidant":[192,331],"capacity":[193],"(TAC),":[194],"cholesterol":[196,261],"phospholipids":[198],"(C/P)":[199],"ratio":[200],"at":[201,311],"both":[202],"fresh":[203],"stages.":[206],"Evaluation":[207],"ROS,":[209],"mitochondrial":[210],"potential":[212,222,332],"(MMP),":[213],"capacitation":[214,288],"status":[215],"(CTC":[216],"assay),":[217],"vitro":[220],"fertility":[221],"conducted":[224],"only":[225],"frozen-thawed":[227],"samples.":[228],"RESULTS:":[229],"The":[230,349],"addition":[231],"\u03bcM)":[236,240,355],"significantly":[245,278],"(p":[246,279],"<":[247,280],"0.05)":[248,281],"improved":[249,340],"terms":[254],"TAC,":[260],"content,":[262],"C/P":[263],"ratio,":[264],"MMP,":[265],"Chlortetracycline":[266],"(CTC)-Full":[267],"(F)":[268],"pattern,":[269],"zona":[271],"binding":[272],"ability":[273],"while":[277],"reduced":[282],"production,":[284],"like":[289,395],"changes":[290,396],"compared":[292],"control":[295],"group.":[296,348],"DISCUSSION:":[297],"As":[298],"acts":[301],"an":[303],"SOD":[304],"mimetic":[305],"also":[307,338,410],"detoxifies":[308],"ferrous":[309],"iron":[310],"level,":[314],"it":[315],"aids":[316],"neutralization":[318],"excessive":[320],"minimizes":[324],"oxidative":[325],"stress-related":[326],"damages":[327],"enhances":[329],"sperm":[334,407,432,448],"mitochondria.":[335],"Earlier":[336],"studies":[337],"indicated":[339,437],"\u03bcM":[346],"improvement":[350],"observed":[351],"might":[357],"be":[358],"inhibition":[361,414],"Nicotinamide":[363],"adenine":[364],"dinucleotide":[365],"phosphate":[366],"(NADPH)":[367],"oxidase":[368],"enzyme":[371],"activation":[372,382,398],"by":[373],"various":[374],"physical/chemical":[375],"inducers":[376],"during":[377],"cryopreservation":[378],"process":[379],"leads":[380],"CatSper":[384],"channel":[385],"resulting":[386],"calcium":[388],"influx,":[389],"premature":[390],"capacitation,":[391],"acrosomal":[393],"reaction":[394],"through":[397],"adenylate":[400],"cyclase":[401],"cAMP/PKA-mediated":[403],"tyrosine":[404],"phosphorylation":[405],"proteins.":[408],"Acetovanillone":[409],"prevents":[411],"NADPH":[412],"oxidase-mediated":[413],"glutathione":[416],"reductase":[417],"activity,":[418],"which":[419],"has":[420],"vital":[422],"role":[423],"protecting":[425],"structural":[427],"functional":[429],"integrity":[430],"CONCLUSION:":[435],"Results":[436],"beneficial":[438],"efficient":[455],"sustaining":[461],"quality.":[464]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":2}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2022-01-25T00:00:00"}