{"id":"https://openalex.org/W4206345609","doi":"https://doi.org/10.1111/apha.13753","title":"Oral Communications","display_name":"Oral Communications","publication_year":2022,"publication_date":"2022-01-14","ids":{"openalex":"https://openalex.org/W4206345609","doi":"https://doi.org/10.1111/apha.13753"},"language":"en","primary_location":{"id":"doi:10.1111/apha.13753","doi":"https://doi.org/10.1111/apha.13753","is_oa":true,"landing_page_url":"https://doi.org/10.1111/apha.13753","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/apha.13753","source":{"id":"https://openalex.org/S204890612","display_name":"Acta Physiologica","issn_l":"1748-1708","issn":["1748-1708","1748-1716"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Physiologica","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/apha.13753","any_repository_has_fulltext":false},"authorships":[],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4450,"currency":"USD","value_usd":4450},"apc_paid":null,"fwci":0.1386,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.37191004,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"234","issue":"S724","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12229","display_name":"Pharmacological Effects and Toxicity Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/5-ht7-receptor","display_name":"5-HT7 receptor","score":0.9419999718666077},{"id":"https://openalex.org/keywords/serotonin-receptors","display_name":"serotonin receptors","score":0.6159999966621399},{"id":"https://openalex.org/keywords/penicillin-induced-epilepsy","display_name":"penicillin-induced epilepsy","score":0.8489999771118164},{"id":"https://openalex.org/keywords/epileptiform-activity","display_name":"epileptiform activity","score":0.984000027179718},{"id":"https://openalex.org/keywords/sb-269970","display_name":"SB-269970","score":0.9940000176429749},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.8169999718666077},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.9990000128746033},{"id":"https://openalex.org/keywords/anticonvulsant-activity","display_name":"anticonvulsant activity","score":0.9340000152587891},{"id":"https://openalex.org/keywords/proconvulsant-effects","display_name":"proconvulsant effects","score":0.6769999861717224},{"id":"https://openalex.org/keywords/spike-rate","display_name":"spike frequency","score":0.5090000033378601},{"id":"https://openalex.org/keywords/malondialdehyde","display_name":"malondialdehyde","score":0.7300000190734863},{"id":"https://openalex.org/keywords/superoxide-dismutase","display_name":"superoxide dismutase","score":0.9679999947547913},{"id":"https://openalex.org/keywords/catalase","display_name":"catalase","score":0.9779999852180481},{"id":"https://openalex.org/keywords/glutathione","display_name":"glutathione","score":0.9990000128746033},{"id":"https://openalex.org/keywords/intracerebroventricular-injection","display_name":"intracerebroventricular administration","score":0.8040000200271606}],"concepts":[{"id":"https://openalex.org/C2778805511","wikidata":"https://www.wikidata.org/wiki/Q1713","display_name":"Citation","level":2,"score":0.6233067512512207},{"id":"https://openalex.org/C2781121862","wikidata":"https://www.wikidata.org/wiki/Q256","display_name":"Turkish","level":2,"score":0.4962356686592102},{"id":"https://openalex.org/C161191863","wikidata":"https://www.wikidata.org/wiki/Q199655","display_name":"Library science","level":1,"score":0.47470465302467346},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3824900686740875},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.345769464969635},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.14325612783432007},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1111/apha.13753","doi":"https://doi.org/10.1111/apha.13753","is_oa":true,"landing_page_url":"https://doi.org/10.1111/apha.13753","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/apha.13753","source":{"id":"https://openalex.org/S204890612","display_name":"Acta Physiologica","issn_l":"1748-1708","issn":["1748-1708","1748-1716"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Physiologica","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1111/apha.13753","doi":"https://doi.org/10.1111/apha.13753","is_oa":true,"landing_page_url":"https://doi.org/10.1111/apha.13753","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/apha.13753","source":{"id":"https://openalex.org/S204890612","display_name":"Acta Physiologica","issn_l":"1748-1708","issn":["1748-1708","1748-1716"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Physiologica","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G671452033","display_name":null,"funder_award_id":"118S245","funder_id":"https://openalex.org/F4320322626","funder_display_name":"T\u00fcrkiye Bilimsel ve Teknolojik Ara\u015ft\u0131rma Kurumu"},{"id":"https://openalex.org/G8428369828","display_name":"Absans Epilepsinin Wag/Rij S\u0131\u00e7an Modelinde Ginkgo Biloban\u0131n N\u00f6ronal Eksitabiliteye Etkileri \u00dczerine Kar\u015f\u0131la\u015ft\u0131rmal\u0131 Bir Ara\u015ft\u0131rma: Bir In Vivo Elektrofizyolojik Ve In Vitro Kalsiyum G\u00f6r\u00fcnt\u00fcleme \u00c7al\u0131\u015fmas\u0131","funder_award_id":"115S348","funder_id":"https://openalex.org/F4320322626","funder_display_name":"T\u00fcrkiye Bilimsel ve Teknolojik Ara\u015ft\u0131rma Kurumu"}],"funders":[{"id":"https://openalex.org/F4320321688","display_name":"Erciyes \u00dcniversitesi","ror":"https://ror.org/047g8vk19"},{"id":"https://openalex.org/F4320322626","display_name":"T\u00fcrkiye Bilimsel ve Teknolojik Ara\u015ft\u0131rma Kurumu","ror":"https://ror.org/04w9kkr77"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4206345609.pdf","grobid_xml":"https://content.openalex.org/works/W4206345609.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2904797649","https://openalex.org/W2050856956","https://openalex.org/W4412108791","https://openalex.org/W3087531134","https://openalex.org/W2022927857","https://openalex.org/W4282969717","https://openalex.org/W4387462069","https://openalex.org/W4386531394","https://openalex.org/W2364484784","https://openalex.org/W4223424648"],"abstract_inverted_index":{"AIM:":[0],"Penicillin-induced":[1],"epileptiform":[2,41,246],"activity":[3,42,247],"is":[4,14],"widely":[5],"used":[6,67,161],"as":[7],"an":[8],"acute":[9],"seizure":[10],"model.The":[11],"5-HT7":[12,36],"receptor":[13,20,38],"the":[15,33,44,114,143,169,185,196,222,241,250,257],"most":[16],"recently":[17],"described":[18],"5-HT":[19],"member.Oxidative":[21],"stress":[22,231],"affects":[23],"many":[24],"physiological":[25,259],"mechanisms,":[26],"including":[27],"epilepsy.The":[28],"study":[29,165],"aims":[30],"to":[31,184],"investigate":[32],"effect":[34,52,243,252],"of":[35,46,74,79,91,117,153,191,202,253,261],"serotonin":[37],"on":[39,244],"penicillininduced":[40],"and":[43,55,85,89,97,112,120,134,145,155,214,248],"role":[45],"reactive":[47],"oxygen":[48],"species":[49],"in":[50,142],"this":[51,59,262],"by":[53,139,168,178],"electrophysiological":[54],"biochemical":[56],"methods.METHODS:":[57],"In":[58],"study,":[60],"male":[61],"albino":[62],"Wistar":[63],"rats":[64],"(180-240g)":[65],"were":[66,101,107,123,127,137,160,219],"(each":[68],"group":[69],"n:6).30":[70],"minutes":[71],"after":[72],"induction":[73],"epilepsy":[75],"via":[76],"penicillin,":[77],"agonist":[78],"5-HT7,":[80,92],"AS":[81,118,192,212,238],"19":[82,119,193,213,228,239],"(1,25,":[83],"0,625":[84,98,188,210],"0,3125":[86],"\u03bcg/rat)":[87,99],"doses":[88,100,116],"selective-antagonist":[90],"SB":[93,121,203,217,235,254],"269970":[94,122,204,218,236],"(2.5,":[95],"1,25":[96,215],"administered":[102],"intracerebroventricularly.":[103],"The":[104],"ECOG":[105],"recordings":[106],"analyzed":[108],"for":[109,162],"spike":[110,197,207,223],"frequency":[111,198,208,224],"amplitude.After":[113],"effective":[115],"determined,":[124],"their":[125],"combinations":[126],"also":[128],"applied":[129],"intracerebroventricularly.Malondialdehyde,":[130],"superoxide":[131],"dismutase,":[132],"catalase":[133],"glutathione":[135],"levels":[136],"measured":[138],"ELISA":[140],"method":[141],"plasma":[144],"tissue":[146],"samples":[147],"from":[148],"different":[149],"brain":[150],"regions.One-way":[151],"analysis":[152],"variance":[154],"Post":[156],"Hoc":[157],"Tukey":[158],"tests":[159],"statistical":[163],"analysis.This":[164],"was":[166,176],"approved":[167],"local":[170],"ethics":[171],"committee":[172],"(HADYEK,":[173],"2017/55).This":[174],"project":[175],"supported":[177],"T\u00dcB\u0130TAK":[179],"(Project":[180],"Number:":[181],"119S194).RESULTS:":[182],"Compared":[183],"control":[186],"group,":[187],"\u03bcg":[189,200,211,216],"dose":[190,201],"significantly":[194,205,226],"reduced":[195],"(p<0.01).1,25":[199],"increased":[206],"(p<0.05).When":[209],"given":[220],"together,":[221],"decreased":[225,229],"(p<0.05).AS":[227],"oxidative":[230],"parameters":[232],"(p<0.05),but":[233],"not":[234],"(p>0.05).CONCLUSION:":[237],"showed":[240],"anticonvulsant":[242],"penicillin-induced":[245],"blocked":[249],"proconvulsive":[251],"269970.To":[255],"elucidate":[256],"detailed":[258],"mechanism":[260],"result,":[263],"it":[264],"needs":[265],"further":[266],"molecular":[267],"studies.":[268]},"counts_by_year":[{"year":2023,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2022-01-25T00:00:00"}