{"id":"https://openalex.org/W4205299402","doi":"https://doi.org/10.3390/children9010042","title":"Adipokines Profile and Inflammation Biomarkers in Prepubertal Population with Obesity and Healthy Metabolic State","display_name":"Adipokines Profile and Inflammation Biomarkers in Prepubertal Population with Obesity and Healthy Metabolic State","publication_year":2022,"publication_date":"2022-01-02","ids":{"openalex":"https://openalex.org/W4205299402","doi":"https://doi.org/10.3390/children9010042","pmid":"https://pubmed.ncbi.nlm.nih.gov/35053667","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8774044"},"language":"en","primary_location":{"id":"doi:10.3390/children9010042","doi":"https://doi.org/10.3390/children9010042","is_oa":true,"landing_page_url":"https://doi.org/10.3390/children9010042","pdf_url":null,"source":{"id":"https://openalex.org/S2736895435","display_name":"Children","issn_l":"2227-9067","issn":["2227-9067"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Children","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3390/children9010042","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044673530","display_name":"Lidia Cobos-Palacios","orcid":"https://orcid.org/0000-0003-4401-233X","observed_orcids":["https://orcid.org/0000-0003-4401-233X"]},"institutions":[{"id":"https://openalex.org/I4210108548","display_name":"Hospital Regional Universitario de M\u00e1laga","ror":"https://ror.org/01mqsmm97","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210108548"]},{"id":"https://openalex.org/I4210164724","display_name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga","ror":"https://ror.org/05n3asa33","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210164724"]},{"id":"https://openalex.org/I82767444","display_name":"Universidad de M\u00e1laga","ror":"https://ror.org/036b2ww28","country_code":"ES","type":"education","lineage":["https://openalex.org/I82767444"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Lidia Cobos-Palacios","raw_affiliation_strings":["Department of Internal Medicine, Instituto de Investigacion Biomedica de M\u00e1laga (IBIMA), Regional University Hospital of M\u00e1laga, University of M\u00e1laga, 29010 M\u00e1laga, Spain"],"raw_orcid":"https://orcid.org/0000-0003-4401-233X","affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Instituto de Investigacion Biomedica de M\u00e1laga (IBIMA), Regional University Hospital of M\u00e1laga, University of M\u00e1laga, 29010 M\u00e1laga, Spain","institution_ids":["https://openalex.org/I4210108548","https://openalex.org/I4210164724","https://openalex.org/I82767444"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083564301","display_name":"M\u00f3nica Mu\u00f1oz-\u00dabeda","orcid":"https://orcid.org/0000-0001-9867-3614","observed_orcids":["https://orcid.org/0000-0001-9867-3614"]},"institutions":[{"id":"https://openalex.org/I4210108548","display_name":"Hospital Regional Universitario de M\u00e1laga","ror":"https://ror.org/01mqsmm97","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210108548"]},{"id":"https://openalex.org/I4210164724","display_name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga","ror":"https://ror.org/05n3asa33","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210164724"]},{"id":"https://openalex.org/I82767444","display_name":"Universidad de M\u00e1laga","ror":"https://ror.org/036b2ww28","country_code":"ES","type":"education","lineage":["https://openalex.org/I82767444"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"M\u00f3nica Mu\u00f1oz-\u00dabeda","raw_affiliation_strings":["Department of Internal Medicine, Instituto de Investigacion Biomedica de M\u00e1laga (IBIMA), Regional University Hospital of M\u00e1laga, University of M\u00e1laga, 29010 M\u00e1laga, Spain"],"raw_orcid":"https://orcid.org/0000-0001-9867-3614","affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Instituto de Investigacion Biomedica de M\u00e1laga (IBIMA), Regional University Hospital of M\u00e1laga, University of M\u00e1laga, 29010 M\u00e1laga, Spain","institution_ids":["https://openalex.org/I4210108548","https://openalex.org/I4210164724","https://openalex.org/I82767444"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033282958","display_name":"Cristina Gallardo\u2010Escribano","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210108548","display_name":"Hospital Regional Universitario de M\u00e1laga","ror":"https://ror.org/01mqsmm97","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210108548"]},{"id":"https://openalex.org/I4210164724","display_name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga","ror":"https://ror.org/05n3asa33","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210164724"]},{"id":"https://openalex.org/I82767444","display_name":"Universidad de M\u00e1laga","ror":"https://ror.org/036b2ww28","country_code":"ES","type":"education","lineage":["https://openalex.org/I82767444"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Cristina Gallardo-Escribano","raw_affiliation_strings":["Department of Internal Medicine, Instituto de Investigacion Biomedica de M\u00e1laga (IBIMA), Regional University Hospital of M\u00e1laga, University of M\u00e1laga, 29010 M\u00e1laga, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Instituto de Investigacion Biomedica de M\u00e1laga (IBIMA), Regional University Hospital of M\u00e1laga, University of M\u00e1laga, 29010 M\u00e1laga, Spain","institution_ids":["https://openalex.org/I4210108548","https://openalex.org/I4210164724","https://openalex.org/I82767444"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051174812","display_name":"Maria Isabel Ruiz-Moreno","orcid":"https://orcid.org/0000-0002-6892-4934","observed_orcids":["https://orcid.org/0000-0002-6892-4934"]},"institutions":[{"id":"https://openalex.org/I4210108548","display_name":"Hospital Regional Universitario de M\u00e1laga","ror":"https://ror.org/01mqsmm97","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210108548"]},{"id":"https://openalex.org/I4210164724","display_name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga","ror":"https://ror.org/05n3asa33","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210164724"]},{"id":"https://openalex.org/I82767444","display_name":"Universidad de M\u00e1laga","ror":"https://ror.org/036b2ww28","country_code":"ES","type":"education","lineage":["https://openalex.org/I82767444"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Mar\u00eda Isabel Ruiz-Moreno","raw_affiliation_strings":["Department of Internal Medicine, Instituto de Investigacion Biomedica de M\u00e1laga (IBIMA), Regional University Hospital of M\u00e1laga, University of M\u00e1laga, 29010 M\u00e1laga, Spain"],"raw_orcid":"https://orcid.org/0000-0002-6892-4934","affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Instituto de Investigacion Biomedica de M\u00e1laga (IBIMA), Regional University Hospital of M\u00e1laga, University of M\u00e1laga, 29010 M\u00e1laga, Spain","institution_ids":["https://openalex.org/I4210108548","https://openalex.org/I4210164724","https://openalex.org/I82767444"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007044639","display_name":"Alberto Vilches-P\u00e9rez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210164724","display_name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga","ror":"https://ror.org/05n3asa33","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210164724"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Alberto Vilches-P\u00e9rez","raw_affiliation_strings":["Department of Endocrinology and Nutrition, Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga (IBIMA), University Hospital Virgen de la Victoria, 29010 M\u00e1laga, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology and Nutrition, Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga (IBIMA), University Hospital Virgen de la Victoria, 29010 M\u00e1laga, Spain","institution_ids":["https://openalex.org/I4210164724"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017277156","display_name":"Antonio Vargas\u2010Candela","orcid":"https://orcid.org/0000-0003-0565-7514","observed_orcids":["https://orcid.org/0000-0003-0565-7514"]},"institutions":[{"id":"https://openalex.org/I4210108548","display_name":"Hospital Regional Universitario de M\u00e1laga","ror":"https://ror.org/01mqsmm97","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210108548"]},{"id":"https://openalex.org/I4210164724","display_name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga","ror":"https://ror.org/05n3asa33","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210164724"]},{"id":"https://openalex.org/I82767444","display_name":"Universidad de M\u00e1laga","ror":"https://ror.org/036b2ww28","country_code":"ES","type":"education","lineage":["https://openalex.org/I82767444"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Antonio Vargas-Candela","raw_affiliation_strings":["Department of Internal Medicine, Instituto de Investigacion Biomedica de M\u00e1laga (IBIMA), Regional University Hospital of M\u00e1laga, University of M\u00e1laga, 29010 M\u00e1laga, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Instituto de Investigacion Biomedica de M\u00e1laga (IBIMA), Regional University Hospital of M\u00e1laga, University of M\u00e1laga, 29010 M\u00e1laga, Spain","institution_ids":["https://openalex.org/I4210108548","https://openalex.org/I4210164724","https://openalex.org/I82767444"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044880483","display_name":"Isabel Leiva Gea","orcid":"https://orcid.org/0000-0002-2259-7253","observed_orcids":["https://orcid.org/0000-0002-2259-7253"]},"institutions":[{"id":"https://openalex.org/I4210108548","display_name":"Hospital Regional Universitario de M\u00e1laga","ror":"https://ror.org/01mqsmm97","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210108548"]},{"id":"https://openalex.org/I4210164724","display_name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga","ror":"https://ror.org/05n3asa33","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210164724"]},{"id":"https://openalex.org/I82767444","display_name":"Universidad de M\u00e1laga","ror":"https://ror.org/036b2ww28","country_code":"ES","type":"education","lineage":["https://openalex.org/I82767444"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Isabel Leiva-Gea","raw_affiliation_strings":["Department of Pediatric Endocrinology, Instituto de Investigacion Biomedica de M\u00e1laga (IBIMA), Regional University Hospital of M\u00e1laga, University of M\u00e1laga, 29010 M\u00e1laga, Spain"],"raw_orcid":"https://orcid.org/0000-0002-2259-7253","affiliations":[{"raw_affiliation_string":"Department of Pediatric Endocrinology, Instituto de Investigacion Biomedica de M\u00e1laga (IBIMA), Regional University Hospital of M\u00e1laga, University of M\u00e1laga, 29010 M\u00e1laga, Spain","institution_ids":["https://openalex.org/I4210108548","https://openalex.org/I4210164724","https://openalex.org/I82767444"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061677162","display_name":"Francisco Jos\u00e9 Tinahones","orcid":"https://orcid.org/0000-0001-6871-4403","observed_orcids":["https://orcid.org/0000-0001-6871-4403"]},"institutions":[{"id":"https://openalex.org/I2801357902","display_name":"Instituto de Salud Carlos III","ror":"https://ror.org/00ca2c886","country_code":"ES","type":"nonprofit","lineage":["https://openalex.org/I2801357902","https://openalex.org/I4387152914"]},{"id":"https://openalex.org/I4210115082","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red","ror":"https://ror.org/02g87qh62","country_code":"ES","type":"facility","lineage":["https://openalex.org/I2801357902","https://openalex.org/I4210115082","https://openalex.org/I4387152914"]},{"id":"https://openalex.org/I4210164724","display_name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga","ror":"https://ror.org/05n3asa33","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210164724"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Francisco J. Tinahones","raw_affiliation_strings":["CIBER Fisiopatologia de la Obesidad y la Nutricion, Carlos III Health Institute, 28029 Madrid, Spain","Department of Endocrinology and Nutrition, Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga (IBIMA), University Hospital Virgen de la Victoria, 29010 M\u00e1laga, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CIBER Fisiopatologia de la Obesidad y la Nutricion, Carlos III Health Institute, 28029 Madrid, Spain","institution_ids":["https://openalex.org/I2801357902","https://openalex.org/I4210115082"]},{"raw_affiliation_string":"Department of Endocrinology and Nutrition, Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga (IBIMA), University Hospital Virgen de la Victoria, 29010 M\u00e1laga, Spain","institution_ids":["https://openalex.org/I4210164724"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067333354","display_name":"Ricardo G\u00f3mez\u2010Huelgas","orcid":"https://orcid.org/0000-0002-9909-3555","observed_orcids":["https://orcid.org/0000-0002-9909-3555"]},"institutions":[{"id":"https://openalex.org/I2801357902","display_name":"Instituto de Salud Carlos III","ror":"https://ror.org/00ca2c886","country_code":"ES","type":"nonprofit","lineage":["https://openalex.org/I2801357902","https://openalex.org/I4387152914"]},{"id":"https://openalex.org/I4210108548","display_name":"Hospital Regional Universitario de M\u00e1laga","ror":"https://ror.org/01mqsmm97","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210108548"]},{"id":"https://openalex.org/I4210115082","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red","ror":"https://ror.org/02g87qh62","country_code":"ES","type":"facility","lineage":["https://openalex.org/I2801357902","https://openalex.org/I4210115082","https://openalex.org/I4387152914"]},{"id":"https://openalex.org/I4210164724","display_name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga","ror":"https://ror.org/05n3asa33","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210164724"]},{"id":"https://openalex.org/I82767444","display_name":"Universidad de M\u00e1laga","ror":"https://ror.org/036b2ww28","country_code":"ES","type":"education","lineage":["https://openalex.org/I82767444"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Ricardo G\u00f3mez-Huelgas","raw_affiliation_strings":["CIBER Fisiopatologia de la Obesidad y la Nutricion, Carlos III Health Institute, 28029 Madrid, Spain","Department of Internal Medicine, Instituto de Investigacion Biomedica de M\u00e1laga (IBIMA), Regional University Hospital of M\u00e1laga, University of M\u00e1laga, 29010 M\u00e1laga, Spain"],"raw_orcid":"https://orcid.org/0000-0002-9909-3555","affiliations":[{"raw_affiliation_string":"CIBER Fisiopatologia de la Obesidad y la Nutricion, Carlos III Health Institute, 28029 Madrid, Spain","institution_ids":["https://openalex.org/I2801357902","https://openalex.org/I4210115082"]},{"raw_affiliation_string":"Department of Internal Medicine, Instituto de Investigacion Biomedica de M\u00e1laga (IBIMA), Regional University Hospital of M\u00e1laga, University of M\u00e1laga, 29010 M\u00e1laga, Spain","institution_ids":["https://openalex.org/I4210108548","https://openalex.org/I4210164724","https://openalex.org/I82767444"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5036360770","display_name":"Mar\u00eda Rosa Bernal-L\u00f3pez","orcid":"https://orcid.org/0000-0002-0238-0890","observed_orcids":["https://orcid.org/0000-0002-0238-0890"]},"institutions":[{"id":"https://openalex.org/I2801357902","display_name":"Instituto de Salud Carlos III","ror":"https://ror.org/00ca2c886","country_code":"ES","type":"nonprofit","lineage":["https://openalex.org/I2801357902","https://openalex.org/I4387152914"]},{"id":"https://openalex.org/I4210108548","display_name":"Hospital Regional Universitario de M\u00e1laga","ror":"https://ror.org/01mqsmm97","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210108548"]},{"id":"https://openalex.org/I4210115082","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red","ror":"https://ror.org/02g87qh62","country_code":"ES","type":"facility","lineage":["https://openalex.org/I2801357902","https://openalex.org/I4210115082","https://openalex.org/I4387152914"]},{"id":"https://openalex.org/I4210164724","display_name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga","ror":"https://ror.org/05n3asa33","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210164724"]},{"id":"https://openalex.org/I82767444","display_name":"Universidad de M\u00e1laga","ror":"https://ror.org/036b2ww28","country_code":"ES","type":"education","lineage":["https://openalex.org/I82767444"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Mar\u00eda Rosa Bernal-L\u00f3pez","raw_affiliation_strings":["CIBER Fisiopatologia de la Obesidad y la Nutricion, Carlos III Health Institute, 28029 Madrid, Spain","Department of Internal Medicine, Instituto de Investigacion Biomedica de M\u00e1laga (IBIMA), Regional University Hospital of M\u00e1laga, University of M\u00e1laga, 29010 M\u00e1laga, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CIBER Fisiopatologia de la Obesidad y la Nutricion, Carlos III Health Institute, 28029 Madrid, Spain","institution_ids":["https://openalex.org/I2801357902","https://openalex.org/I4210115082"]},{"raw_affiliation_string":"Department of Internal Medicine, Instituto de Investigacion Biomedica de M\u00e1laga (IBIMA), Regional University Hospital of M\u00e1laga, University of M\u00e1laga, 29010 M\u00e1laga, Spain","institution_ids":["https://openalex.org/I4210108548","https://openalex.org/I4210164724","https://openalex.org/I82767444"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5036360770","https://openalex.org/A5067333354"],"corresponding_institution_ids":["https://openalex.org/I2801357902","https://openalex.org/I4210108548","https://openalex.org/I4210115082","https://openalex.org/I4210164724","https://openalex.org/I82767444"],"apc_list":{"value":1800,"currency":"CHF","value_usd":1885},"apc_paid":{"value":1800,"currency":"CHF","value_usd":1885},"fwci":1.9924,"has_fulltext":true,"cited_by_count":15,"citation_normalized_percentile":{"value":0.85766211,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"9","issue":"1","first_page":"42","last_page":"42"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10010","display_name":"Obesity, Physical Activity, Diet","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12979","display_name":"Cardiovascular Disease and Adiposity","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/metabolically-healthy-obesity","display_name":"metabolically healthy obesity","score":0.8939999938011169},{"id":"https://openalex.org/keywords/childhood-obesity","display_name":"childhood obesity","score":0.781000018119812},{"id":"https://openalex.org/keywords/prepubertal-children","display_name":"prepubertal children","score":0.9120000004768372},{"id":"https://openalex.org/keywords/adipokines","display_name":"adipokines","score":0.972000002861023},{"id":"https://openalex.org/keywords/adiponectin","display_name":"adiponectin","score":0.8259999752044678},{"id":"https://openalex.org/keywords/resistin","display_name":"resistin","score":1.0},{"id":"https://openalex.org/keywords/inflammatory-markers","display_name":"inflammatory markers","score":0.8100000023841858},{"id":"https://openalex.org/keywords/c-reactive-protein","display_name":"C-reactive protein","score":0.9829999804496765},{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":0.9980000257492065},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.9629999995231628},{"id":"https://openalex.org/keywords/mediterranean-diet","display_name":"Mediterranean diet","score":0.9959999918937683},{"id":"https://openalex.org/keywords/exercise","display_name":"physical activity","score":0.9039999842643738},{"id":"https://openalex.org/keywords/lifestyle-modification","display_name":"lifestyle modification","score":0.9120000004768372},{"id":"https://openalex.org/keywords/body-mass-index","display_name":"body mass index","score":0.6669999957084656},{"id":"https://openalex.org/keywords/adipose-tissue-inflammation","display_name":"adipose tissue inflammation","score":0.7059999704360962},{"id":"https://openalex.org/keywords/weight-loss-interventions","display_name":"weight loss interventions","score":0.5080000162124634},{"id":"https://openalex.org/keywords/anthropometric-measures","display_name":"anthropometric measures","score":0.5130000114440918},{"id":"https://openalex.org/keywords/andalusia","display_name":"Andalusia","score":0.921999990940094}],"concepts":[{"id":"https://openalex.org/C194832188","wikidata":"https://www.wikidata.org/wiki/Q2638593","display_name":"Adipokine","level":4,"score":0.8333094120025635},{"id":"https://openalex.org/C2779760629","wikidata":"https://www.wikidata.org/wiki/Q419499","display_name":"Resistin","level":5,"score":0.821294367313385},{"id":"https://openalex.org/C2776782570","wikidata":"https://www.wikidata.org/wiki/Q357439","display_name":"Adiponectin","level":4,"score":0.8159507513046265},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7526865601539612},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6970070600509644},{"id":"https://openalex.org/C2776193436","wikidata":"https://www.wikidata.org/wiki/Q236232","display_name":"Waist","level":3,"score":0.6623011231422424},{"id":"https://openalex.org/C2780221984","wikidata":"https://www.wikidata.org/wiki/Q131191","display_name":"Body mass index","level":2,"score":0.5914031863212585},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5484283566474915},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5347926020622253},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.5323042869567871},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.4379725754261017},{"id":"https://openalex.org/C2778270857","wikidata":"https://www.wikidata.org/wiki/Q2723972","display_name":"Lipid profile","level":3,"score":0.43654578924179077},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.3001220226287842},{"id":"https://openalex.org/C2780613262","wikidata":"https://www.wikidata.org/wiki/Q223739","display_name":"Leptin","level":3,"score":0.16995137929916382},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.15618419647216797},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.3390/children9010042","doi":"https://doi.org/10.3390/children9010042","is_oa":true,"landing_page_url":"https://doi.org/10.3390/children9010042","pdf_url":null,"source":{"id":"https://openalex.org/S2736895435","display_name":"Children","issn_l":"2227-9067","issn":["2227-9067"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Children","raw_type":"journal-article"},{"id":"pmid:35053667","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35053667","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Children (Basel, Switzerland)","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8774044","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8774044/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Children (Basel)","raw_type":"Text"},{"id":"pmh:oai:www.repositoriosalud.es:10668/20943","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774044/pdf","pdf_url":"https://www.mdpi.com/2227-9067/9/1/42/pdf?version=1641347953","source":{"id":"https://openalex.org/S4377196114","display_name":"RISalud Institutional Health Repository of Andaluc\u00eda","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"research article"},{"id":"pmh:oai:doaj.org/article:b0a0f3960779423aa83f71453656944f","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/b0a0f3960779423aa83f71453656944f","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Children, Vol 9, Iss 1, p 42 (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/children9010042","doi":"https://doi.org/10.3390/children9010042","is_oa":true,"landing_page_url":"https://doi.org/10.3390/children9010042","pdf_url":null,"source":{"id":"https://openalex.org/S2736895435","display_name":"Children","issn_l":"2227-9067","issn":["2227-9067"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Children","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4205299402.pdf","grobid_xml":"https://content.openalex.org/works/W4205299402.grobid-xml"},"referenced_works_count":62,"referenced_works":["https://openalex.org/W1491077479","https://openalex.org/W1520348292","https://openalex.org/W1860497814","https://openalex.org/W1910806356","https://openalex.org/W1963619735","https://openalex.org/W1974033843","https://openalex.org/W1989020172","https://openalex.org/W1998205673","https://openalex.org/W2013521697","https://openalex.org/W2032095106","https://openalex.org/W2038869287","https://openalex.org/W2039376486","https://openalex.org/W2040456667","https://openalex.org/W2041734239","https://openalex.org/W2057921119","https://openalex.org/W2068245483","https://openalex.org/W2075881404","https://openalex.org/W2076891551","https://openalex.org/W2077248057","https://openalex.org/W2082977256","https://openalex.org/W2096876054","https://openalex.org/W2097237608","https://openalex.org/W2101099513","https://openalex.org/W2104129218","https://openalex.org/W2109694442","https://openalex.org/W2114280375","https://openalex.org/W2118969396","https://openalex.org/W2126545477","https://openalex.org/W2129295604","https://openalex.org/W2129456294","https://openalex.org/W2129785124","https://openalex.org/W2130138331","https://openalex.org/W2141393362","https://openalex.org/W2152436391","https://openalex.org/W2155108685","https://openalex.org/W2156255408","https://openalex.org/W2169051923","https://openalex.org/W2169918634","https://openalex.org/W2411826498","https://openalex.org/W2563935824","https://openalex.org/W2588693623","https://openalex.org/W2619785797","https://openalex.org/W2626755434","https://openalex.org/W2682020735","https://openalex.org/W2739967909","https://openalex.org/W2746990660","https://openalex.org/W2788109417","https://openalex.org/W2808131459","https://openalex.org/W2900522982","https://openalex.org/W2900726805","https://openalex.org/W2909131229","https://openalex.org/W2914133338","https://openalex.org/W2939899653","https://openalex.org/W2964720681","https://openalex.org/W2965823720","https://openalex.org/W2987555034","https://openalex.org/W3035157797","https://openalex.org/W3039571861","https://openalex.org/W3046585788","https://openalex.org/W3046677011","https://openalex.org/W3122663099","https://openalex.org/W6731277901"],"related_works":["https://openalex.org/W4285410791","https://openalex.org/W2939899653","https://openalex.org/W2357248786","https://openalex.org/W2165322684","https://openalex.org/W2142472830","https://openalex.org/W878448311","https://openalex.org/W2549420957","https://openalex.org/W2140591221","https://openalex.org/W2044357202","https://openalex.org/W2130222817"],"abstract_inverted_index":{"(1)":[0],"Background":[1],"and":[2,5,34,47,66,89,135,170,177,189,202,220,237,262,275,288,298,310,348,365],"aims:":[3],"Obesity":[4],"high":[6,45],"body":[7,227,308],"max":[8],"index":[9],"(BMI)":[10],"have":[11,56,95],"been":[12,38],"linked":[13],"to":[14,76,255,329,363],"elevated":[15],"levels":[16,285,290],"of":[17,49,62,129,180,218,267,318,326,332],"inflammation":[18,168],"serum":[19],"markers":[20],"such":[21],"as":[22,125,283],"C-reactive":[23],"protein":[24],"(CRP),":[25],"interleukin-6":[26],"(IL-6),":[27],"tumor":[28],"necrosis":[29],"factor":[30],"alpha":[31],"(TNF-alpha),":[32],"adiponectin,":[33],"resistin.":[35],"It":[36],"has":[37],"described":[39],"that":[40,80],"adipose":[41],"tissue":[42],"presents":[43],"a":[44,84,100,161,204,223,302],"production":[46],"secretion":[48],"these":[50],"diverse":[51],"pro-inflammatory":[52],"molecules,":[53],"which":[54,342],"may":[55],"local":[57],"effects":[58,69],"on":[59,70,96],"the":[60,63,78,130,213,250,281,294,339,356],"physiology":[61],"fat":[64],"cell":[65],"also":[67],"systemic":[68],"other":[71],"organs.":[72],"Our":[73],"aim":[74],"was":[75,247],"evaluate":[77],"impact":[79],"lifestyle":[81,164,319],"modifications,":[82],"following":[83,131],"Mediterranean":[85],"Diet":[86],"(MedDiet)":[87],"program":[88],"physical":[90,311,349],"activity":[91,350],"(PA)":[92],"training,":[93],"would":[94],"inflammatory":[97,258,333],"biomarkers":[98,259,297,334],"in":[99,122,212,226,249,292,338,370,372],"metabolically":[101],"healthy":[102],"prepubertal":[103],"population":[104,252],"with":[105,253,280,305,346],"obesity":[106,371],"(MHOPp)":[107],"from":[108],"Malaga":[109],"(Andalusia,":[110],"Spain).":[111],"(2)":[112],"Methods:":[113],"144":[114,184],"MHOPp":[115,185,322],"subjects":[116,159],"(aged":[117],"5\u20139":[118],"years)":[119],"were":[120,173,196,210,269],"included":[121,211],"this":[123],"study":[124],"they":[126],"met":[127],"\u22641":[128],"criteria:":[132],"waist":[133],"circumference":[134],"blood":[136],"pressure":[137],"\u2265":[138],"90":[139,143],"percentile,":[140],"triglycerides":[141],">":[142],"mg/dL,":[144,151],"high-density":[145],"lipoprotein":[146],"cholesterol":[147],"(HDL-c)":[148],"<":[149,235,245],"40":[150],"or":[152],"impaired":[153],"fasting":[154],"glucose":[155],"(\u2265100":[156],"md/dL).":[157],"Selected":[158],"followed":[160],"personalized":[162],"intensive":[163],"modification.":[165],"Anthropometric":[166],"measurements,":[167],"biomarkers,":[169],"adipokine":[171,299,340],"profile":[172,273,300],"analyzed":[174],"after":[175,264],"12":[176],"24":[178,216,265,316],"months":[179,217,266,317],"intervention.":[181,351],"(3)":[182],"Results:":[183],"participants":[186],"(75":[187],"boys\u201452%":[188],"69":[190],"girls\u201448%;":[191],"p":[192,234,244],"=":[193],"0.62),":[194],"who":[195],"7.8":[197],"\u00b1":[198,207,230,240],"1.4":[199],"years":[200],"old":[201],"had":[203,301],"BMI":[205,238],"24.6":[206],"3.3":[208],"kg/m2,":[209],"study.":[214],"After":[215,315],"MedDiet":[219,347],"daily":[221],"PA,":[222],"significant":[224,303],"decrease":[225],"weight":[228],"(\u22120.5":[229],"0.2":[231,241],"SD":[232,242],"units;":[233,243],"0.0001)":[236,246],"(\u22120.7":[239],"observed":[248],"total":[251],"respect":[254],"baseline.":[256],"Serum":[257],"(IL-6,":[260],"TNF-alpha,":[261],"CRP)":[263],"intervention":[268],"significantly":[270,286],"reduced.":[271],"Adipokine":[272],"(adiponectin":[274],"resistin)":[276],"did":[277],"not":[278,344],"improve":[279,345],"intervention,":[282],"adiponectin":[284],"decreased":[287],"resistin":[289],"increased":[291],"all":[293],"population.":[295],"Inflammatory":[296],"correlation":[304],"anthropometric":[306],"parameters,":[307],"composition,":[309],"activity.":[312],"(4)":[313],"Conclusions:":[314],"modification,":[320],"our":[321],"reduced":[323],"their":[324],"Z-score":[325],"BMI,":[327],"leading":[328],"an":[330,367],"improvement":[331],"but":[335],"inducing":[336],"deterioration":[337],"profile,":[341],"does":[343],"An":[352],"adequate":[353],"education":[354],"within":[355],"family":[357],"about":[358],"healthier":[359],"habits":[360],"is":[361],"necessary":[362],"prevent":[364],"reduce":[366],"excessive":[368],"increase":[369],"childhood.":[373]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2022-01-26T00:00:00"}