{"id":"https://openalex.org/W4200619002","doi":"https://doi.org/10.15360/1813-9779-2021-6-4-14","title":"Adaptive Phage Therapy in the Treatment of Patients with Recurrent Pneumonia (Pilot Study)","display_name":"Adaptive Phage Therapy in the Treatment of Patients with Recurrent Pneumonia (Pilot Study)","publication_year":2021,"publication_date":"2021-12-17","ids":{"openalex":"https://openalex.org/W4200619002","doi":"https://doi.org/10.15360/1813-9779-2021-6-4-14"},"language":"en","primary_location":{"id":"doi:10.15360/1813-9779-2021-6-4-14","doi":"https://doi.org/10.15360/1813-9779-2021-6-4-14","is_oa":true,"landing_page_url":"https://doi.org/10.15360/1813-9779-2021-6-4-14","pdf_url":"https://www.reanimatology.com/rmt/article/download/2153/1568","source":{"id":"https://openalex.org/S4210169628","display_name":"General Reanimatology","issn_l":"1813-9779","issn":["1813-9779","2411-7110"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4310312831","host_organization_name":"Russian Academy of Medical Sciences","host_organization_lineage":["https://openalex.org/P4310312831"],"host_organization_lineage_names":["Russian Academy of Medical Sciences"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"General Reanimatology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.reanimatology.com/rmt/article/download/2153/1568","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048039887","display_name":"Beloborodova Nv","orcid":"https://orcid.org/0000-0003-2328-1610","observed_orcids":["https://orcid.org/0000-0003-2328-1610"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N. V. Beloborodova","raw_affiliation_strings":["Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039991073","display_name":"Andrey V. Grechko","orcid":"https://orcid.org/0000-0003-3318-796X","observed_orcids":["https://orcid.org/0000-0003-3318-796X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A. V. Grechko","raw_affiliation_strings":["Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004763203","display_name":"Marina M. Gurkova","orcid":"https://orcid.org/0000-0001-6473-9566","observed_orcids":["https://orcid.org/0000-0001-6473-9566"]},"institutions":[{"id":"https://openalex.org/I4405255057","display_name":"MicroMir","ror":"https://ror.org/02jpyxx33","country_code":"RU","type":"company","lineage":["https://openalex.org/I4405255057"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"M. M. Gurkova","raw_affiliation_strings":["Research and Production Center \u00abMicroMir\u00bb"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research and Production Center \u00abMicroMir\u00bb","institution_ids":["https://openalex.org/I4405255057"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057798864","display_name":"Alexander Yu. Zurabov","orcid":"https://orcid.org/0009-0005-2318-1566","observed_orcids":["https://orcid.org/0009-0005-2318-1566"]},"institutions":[{"id":"https://openalex.org/I4405255057","display_name":"MicroMir","ror":"https://ror.org/02jpyxx33","country_code":"RU","type":"company","lineage":["https://openalex.org/I4405255057"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"A. Yu. Zurabov","raw_affiliation_strings":["Research and Production Center \u00abMicroMir\u00bb"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research and Production Center \u00abMicroMir\u00bb","institution_ids":["https://openalex.org/I4405255057"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000478178","display_name":"\u0417\u0443\u0440\u0430\u0431\u043e\u0432 \u0424\u0435\u0434\u043e\u0440 \u041c\u0438\u0445\u0430\u0439\u043b\u043e\u0432\u0438\u0447","orcid":"https://orcid.org/0000-0001-7947-1128","observed_orcids":["https://orcid.org/0000-0001-7947-1128"]},"institutions":[{"id":"https://openalex.org/I4405255057","display_name":"MicroMir","ror":"https://ror.org/02jpyxx33","country_code":"RU","type":"company","lineage":["https://openalex.org/I4405255057"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"F. M. Zurabov","raw_affiliation_strings":["Research and Production Center \u00abMicroMir\u00bb"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research and Production Center \u00abMicroMir\u00bb","institution_ids":["https://openalex.org/I4405255057"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083813641","display_name":"Artem N. Kuzovlev","orcid":"https://orcid.org/0000-0002-5930-0118","observed_orcids":["https://orcid.org/0000-0002-5930-0118"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A. N. Kuzovlev","raw_affiliation_strings":["Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079655465","display_name":"A. Yu. Megley","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A. Yu. Megley","raw_affiliation_strings":["Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology","Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, 25 Petrovka Str., 2 bldg, 10703 Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology","institution_ids":[]},{"raw_affiliation_string":"Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, 25 Petrovka Str., 2 bldg, 10703 Moscow, Russia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060244014","display_name":"Marina V. Petrova","orcid":"https://orcid.org/0000-0003-4272-0957","observed_orcids":["https://orcid.org/0000-0003-4272-0957"]},"institutions":[{"id":"https://openalex.org/I126527374","display_name":"Peoples' Friendship University of Russia","ror":"https://ror.org/02dn9h927","country_code":"RU","type":"education","lineage":["https://openalex.org/I126527374"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"M. V. Petrova","raw_affiliation_strings":["Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology;\r\nPeoples' Friendship University of Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology;\r\nPeoples' Friendship University of Russia","institution_ids":["https://openalex.org/I126527374"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026283689","display_name":"\u0412. \u041c. \u041f\u043e\u043f\u043e\u0432\u0430","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405255057","display_name":"MicroMir","ror":"https://ror.org/02jpyxx33","country_code":"RU","type":"company","lineage":["https://openalex.org/I4405255057"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"V. M. Popova","raw_affiliation_strings":["Research and Production Center \u00abMicroMir\u00bb"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research and Production Center \u00abMicroMir\u00bb","institution_ids":["https://openalex.org/I4405255057"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087261233","display_name":"Ivan V. Redkin","orcid":"https://orcid.org/0000-0001-7008-2038","observed_orcids":["https://orcid.org/0000-0001-7008-2038"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"I. V. Redkin","raw_affiliation_strings":["Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060344087","display_name":"N. I. Sergeyev","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210109025","display_name":"Federal State Budgetary Institution Russian Scientific Center of Roentgenoradiology","ror":"https://ror.org/01mqnrz37","country_code":"RU","type":"government","lineage":["https://openalex.org/I4210109025","https://openalex.org/I4210117042"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"N. I. Sergeyev","raw_affiliation_strings":["Russian Scientific Center for Roentgenoradiology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Russian Scientific Center for Roentgenoradiology","institution_ids":["https://openalex.org/I4210109025"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025926828","display_name":"Ekaterina Chernevskaya","orcid":"https://orcid.org/0000-0002-9316-8907","observed_orcids":["https://orcid.org/0000-0002-9316-8907"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E. A. Chernevskaya","raw_affiliation_strings":["Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110965065","display_name":"Mikhail Yu. Yuriev","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. Yu. Yuriev","raw_affiliation_strings":["Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology","Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, 25 Petrovka Str., 2 bldg, 10703 Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology","institution_ids":[]},{"raw_affiliation_string":"Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, 25 Petrovka Str., 2 bldg, 10703 Moscow, Russia","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109617575","display_name":"Alexey \u0410. Yakovlev","orcid":"https://orcid.org/0000-0002-8482-1249","observed_orcids":["https://orcid.org/0000-0002-8482-1249"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A. A. Yakovlev","raw_affiliation_strings":["Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology","Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, 25 Petrovka Str., 2 bldg, 10703 Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology","institution_ids":[]},{"raw_affiliation_string":"Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, 25 Petrovka Str., 2 bldg, 10703 Moscow, Russia","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.8022,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.63954893,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"17","issue":"6","first_page":"4","last_page":"14"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11048","display_name":"Bacteriophages and microbial interactions","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11048","display_name":"Bacteriophages and microbial interactions","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11681","display_name":"Nosocomial Infections in ICU","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10654","display_name":"Pneumonia and Respiratory Infections","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/phage-cocktail","display_name":"phage cocktail","score":0.8859999775886536},{"id":"https://openalex.org/keywords/recurrent-pneumonia","display_name":"recurrent pneumonia","score":0.9959999918937683},{"id":"https://openalex.org/keywords/chronic-critical-illness","display_name":"chronic critical illness","score":0.6840000152587891},{"id":"https://openalex.org/keywords/antibiotic-resistant-bacteria","display_name":"antibiotic-resistant bacteria","score":0.7689999938011169},{"id":"https://openalex.org/keywords/bronchoalveolar-lavage","display_name":"bronchoalveolar lavage","score":0.7730000019073486},{"id":"https://openalex.org/keywords/mechanical-ventilation","display_name":"mechanical ventilation","score":0.5509999990463257},{"id":"https://openalex.org/keywords/lung-injury","display_name":"lung injury","score":0.48100000619888306}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7687667608261108},{"id":"https://openalex.org/C2779256223","wikidata":"https://www.wikidata.org/wiki/Q611870","display_name":"Phage therapy","level":5,"score":0.692643404006958},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.5786741971969604},{"id":"https://openalex.org/C2777914695","wikidata":"https://www.wikidata.org/wiki/Q12192","display_name":"Pneumonia","level":2,"score":0.5533435940742493},{"id":"https://openalex.org/C2776441376","wikidata":"https://www.wikidata.org/wiki/Q165028","display_name":"Bacteriophage","level":4,"score":0.55328369140625},{"id":"https://openalex.org/C2777080012","wikidata":"https://www.wikidata.org/wiki/Q3766250","display_name":"Mechanical ventilation","level":2,"score":0.5439916849136353},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5192099213600159},{"id":"https://openalex.org/C2778375690","wikidata":"https://www.wikidata.org/wiki/Q7814214","display_name":"Tolerability","level":3,"score":0.5014152526855469},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.15952584147453308},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.11390990018844604},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09218421578407288},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.15360/1813-9779-2021-6-4-14","doi":"https://doi.org/10.15360/1813-9779-2021-6-4-14","is_oa":true,"landing_page_url":"https://doi.org/10.15360/1813-9779-2021-6-4-14","pdf_url":"https://www.reanimatology.com/rmt/article/download/2153/1568","source":{"id":"https://openalex.org/S4210169628","display_name":"General Reanimatology","issn_l":"1813-9779","issn":["1813-9779","2411-7110"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4310312831","host_organization_name":"Russian Academy of Medical Sciences","host_organization_lineage":["https://openalex.org/P4310312831"],"host_organization_lineage_names":["Russian Academy of Medical Sciences"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"General Reanimatology","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:d33bcf5a63374356af12075525836d79","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/d33bcf5a63374356af12075525836d79","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"\u041e\u0431\u0449\u0430\u044f \u0440\u0435\u0430\u043d\u0438\u043c\u0430\u0442\u043e\u043b\u043e\u0433\u0438\u044f, Vol 17, Iss 6, Pp 4-14 (2021)","raw_type":"article"},{"id":"pmh:oai:oai.rmt.elpub.ru:article/2141","doi":null,"is_oa":true,"landing_page_url":"https://www.reanimatology.com/rmt/article/view/2141","pdf_url":null,"source":{"id":"https://openalex.org/S4306401755","display_name":"General Reanimatology (Scientific Research Institute of General Reanimatology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210120300","host_organization_name":"V.A. Negovsky Scientific Research Institute of General Reanimatology","host_organization_lineage":["https://openalex.org/I4210120300"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"General Reanimatology; \u041f\u0440\u0438\u043d\u044f\u0442\u043e \u0432 \u043f\u0435\u0447\u0430\u0442\u044c","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:oai.rmt.elpub.ru:article/2153","doi":null,"is_oa":true,"landing_page_url":"https://www.reanimatology.com/rmt/article/view/2153","pdf_url":null,"source":{"id":"https://openalex.org/S4306401755","display_name":"General Reanimatology (Scientific Research Institute of General Reanimatology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210120300","host_organization_name":"V.A. Negovsky Scientific Research Institute of General Reanimatology","host_organization_lineage":["https://openalex.org/I4210120300"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"General Reanimatology; \u0422\u043e\u043c 17, \u2116 6 (2021); 4-14","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.15360/1813-9779-2021-6-4-14","doi":"https://doi.org/10.15360/1813-9779-2021-6-4-14","is_oa":true,"landing_page_url":"https://doi.org/10.15360/1813-9779-2021-6-4-14","pdf_url":"https://www.reanimatology.com/rmt/article/download/2153/1568","source":{"id":"https://openalex.org/S4210169628","display_name":"General Reanimatology","issn_l":"1813-9779","issn":["1813-9779","2411-7110"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4310312831","host_organization_name":"Russian Academy of Medical Sciences","host_organization_lineage":["https://openalex.org/P4310312831"],"host_organization_lineage_names":["Russian Academy of Medical Sciences"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"General Reanimatology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4200619002.pdf","grobid_xml":"https://content.openalex.org/works/W4200619002.grobid-xml"},"referenced_works_count":19,"referenced_works":["https://openalex.org/W1968777410","https://openalex.org/W2061918801","https://openalex.org/W2070373460","https://openalex.org/W2263818957","https://openalex.org/W2484243444","https://openalex.org/W2604057388","https://openalex.org/W2612405489","https://openalex.org/W2921436366","https://openalex.org/W2950541901","https://openalex.org/W2979416990","https://openalex.org/W2980695608","https://openalex.org/W3007565704","https://openalex.org/W3029467025","https://openalex.org/W3080289424","https://openalex.org/W3082283944","https://openalex.org/W3103605505","https://openalex.org/W3120069934","https://openalex.org/W3175417702","https://openalex.org/W3178034838"],"related_works":["https://openalex.org/W4389793596","https://openalex.org/W4394957655","https://openalex.org/W3080593228","https://openalex.org/W7123354841","https://openalex.org/W3133767440","https://openalex.org/W2771818660","https://openalex.org/W7161602018","https://openalex.org/W7155072155","https://openalex.org/W4392641774","https://openalex.org/W2898868611"],"abstract_inverted_index":{"Aim.":[0],"To":[1],"evaluate":[2],"the":[3,8,87,123,147,195,202,210,225,231,237,242,247,258],"safety":[4,226],"and":[5,22,68,75,93,122,134,190,267,279],"efficacy":[6,235],"of":[7,72,78,106,119,125,136,146,208,227,230,236],"adaptive":[9,211],"phage":[10,212,248],"therapy":[11,89,95,213,249],"technique":[12,214,238],"in":[13,18,65,86,104,159,162,194,201,215,220,246,257,274],"patients":[14,32,57,163,219,275],"with":[15,33,90,128,169,260],"recurrent":[16],"pneumonia":[17],"neurological":[19,221],"critical":[20],"care.Material":[21],"methods.":[23],"The":[24,37,52,63,100,180,205,234],"clinical":[25,266],"study":[26],"included":[27,55],"83":[28],"chronically":[29,216],"critically":[30,217],"ill":[31,218],"severe":[34],"brain":[35],"damage.":[36],"bacteriophage":[38,148,232],"cocktail":[39],"selected":[40],"against":[41],"specific":[42],"hospital":[43],"strains":[44],"was":[45,191,239],"administered":[46],"by":[47,241],"inhalation":[48],"to":[49,115,255,271],"43":[50],"patients.":[51],"control":[53,203],"group":[54,197,259],"40":[56],"who":[58,164,276],"received":[59,165,277],"conventional":[60,261],"antimicrobial":[61],"therapy.":[62],"changes":[64],"clinical,":[66],"laboratory":[67,268],"instrumental":[69],"parameters,":[70],"levels":[71],"biomarkers,":[73],"microbiological":[74],"PCR":[76],"tests":[77],"bronchoalveolar":[79],"lavage":[80],"fluid":[81],"were":[82,102,141,252],"assessed,":[83],"including":[84],"those":[85,256],"\u00abphage":[88,94],"antibiotics\u00bb":[91,97],"(n=29)":[92],"without":[96,171],"(n=14)":[98],"subgroups.Results.":[99],"groups":[101],"comparable":[103],"terms":[105],"basic":[107],"parameters":[108,269],"(age,":[109],"sex,":[110],"diagnosis,":[111],"organ":[112],"dysfunction":[113],"according":[114],"APACHE":[116],"II,":[117],"use":[118],"vasoactive":[120],"drugs)":[121],"level":[124],"airway":[126],"colonization":[127],"antibioticresistant":[129],"bacterial":[130],"strains.":[131],"Good":[132],"tolerability":[133],"absence":[135],"clinically":[137],"significant":[138,157],"side":[139],"effects":[140],"observed":[142],"during":[143],"inhaled":[144],"administration":[145,229],"cocktail.":[149,233],"Computed":[150],"tomography":[151],"on":[152,183],"day":[153,184],"21":[154],"showed":[155],"a":[156],"reduction":[158],"lung":[160],"damage":[161],"bacteriophages.":[166],"Patients":[167],"treated":[168],"bacteriophages":[170,278],"antibiotics":[172],"had":[173],"significantly":[174,189],"lower":[175],"need":[176],"for":[177],"mechanical":[178],"ventilation.":[179],"mortality":[181],"rate":[182],"28":[185],"did":[186,280],"not":[187,253,281],"differ":[188],"4.7%":[192],"(2/43)":[193],"bacteriophage-treated":[196],"vs":[198],"5%":[199],"(2/40)":[200],"group.Conclusion.":[204],"first":[206],"experience":[207],"using":[209],"intensive":[222],"care":[223],"demonstrated":[224],"inhalational":[228],"confirmed":[240],"treatment":[243],"results":[244],"obtained":[245],"group,":[250],"which":[251],"inferior":[254],"antibiotic":[262],"therapy,":[263],"while":[264],"several":[265],"tended":[270],"improve":[272],"even":[273],"receive":[282],"antibiotics.":[283]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":1}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2021-12-31T00:00:00"}