{"id":"https://openalex.org/W4200609060","doi":"https://doi.org/10.37219/2528-8253-2021-5-55","title":"Multicentre clinical trial to evaluate microbial spectrum in acute diffuse otitis externa in the residents of Ukraine","display_name":"Multicentre clinical trial to evaluate microbial spectrum in acute diffuse otitis externa in the residents of Ukraine","publication_year":2021,"publication_date":"2021-11-01","ids":{"openalex":"https://openalex.org/W4200609060","doi":"https://doi.org/10.37219/2528-8253-2021-5-55"},"language":"en","primary_location":{"id":"doi:10.37219/2528-8253-2021-5-55","doi":"https://doi.org/10.37219/2528-8253-2021-5-55","is_oa":true,"landing_page_url":"https://doi.org/10.37219/2528-8253-2021-5-55","pdf_url":"http://www.lorlife.kiev.ua/2021/2021_5_55.pdf","source":{"id":"https://openalex.org/S4210232859","display_name":"OTORHINOLARYNGOLOGY","issn_l":"2528-8245","issn":["2528-8245","2528-8253"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"OTORHINOLARYNGOLOGY","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.lorlife.kiev.ua/2021/2021_5_55.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060994390","display_name":"Vasyl Popovych","orcid":"https://orcid.org/0000-0002-2898-8474","observed_orcids":["https://orcid.org/0000-0002-2898-8474"]},"institutions":[{"id":"https://openalex.org/I1323554757","display_name":"Ivano-Frankivsk National Medical University","ror":"https://ror.org/023wxgq18","country_code":"UA","type":"education","lineage":["https://openalex.org/I1323554757"]}],"countries":["UA"],"is_corresponding":true,"raw_author_name":"Vasyl I. Popovych","raw_affiliation_strings":["Ivano-Frankivsk National Medical University"],"raw_orcid":"https://orcid.org/0000-0002-2898-8474","affiliations":[{"raw_affiliation_string":"Ivano-Frankivsk National Medical University","institution_ids":["https://openalex.org/I1323554757"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5060994390"],"corresponding_institution_ids":["https://openalex.org/I1323554757"],"apc_list":null,"apc_paid":null,"fwci":0.0848,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.39065742,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":null,"issue":"No5(4) 2021","first_page":"55","last_page":"61"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12297","display_name":"Otolaryngology and Infectious Diseases","score":0.75,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12297","display_name":"Otolaryngology and Infectious Diseases","score":0.75,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10861","display_name":"Ear Surgery and Otitis Media","score":0.19169999659061432,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11826","display_name":"Ocular Infections and Treatments","score":0.007199999876320362,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bacterial-etiology","display_name":"bacterial etiology","score":0.7120000123977661},{"id":"https://openalex.org/keywords/staphylococcus-aureus","display_name":"Staphylococcus aureus","score":0.906000018119812},{"id":"https://openalex.org/keywords/pseudomonas-aeruginosa","display_name":"Pseudomonas aeruginosa","score":1.0},{"id":"https://openalex.org/keywords/gram-negative-bacteria","display_name":"Gram-negative bacteria","score":0.7760000228881836},{"id":"https://openalex.org/keywords/candida","display_name":"Candida","score":0.6269999742507935},{"id":"https://openalex.org/keywords/staphylococcus-epidermidis","display_name":"Staphylococcus epidermidis","score":0.9959999918937683},{"id":"https://openalex.org/keywords/colony-forming-units","display_name":"colony-forming units","score":0.8600000143051147},{"id":"https://openalex.org/keywords/empirical-antibiotic-therapy","display_name":"empirical antibiotic therapy","score":0.5600000023841858},{"id":"https://openalex.org/keywords/ukrainian-population","display_name":"Ukrainian population","score":0.7039999961853027}],"concepts":[{"id":"https://openalex.org/C2776439223","wikidata":"https://www.wikidata.org/wiki/Q480700","display_name":"Otitis","level":2,"score":0.717208981513977},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6658058166503906},{"id":"https://openalex.org/C2777637488","wikidata":"https://www.wikidata.org/wiki/Q31856","display_name":"Pseudomonas aeruginosa","level":3,"score":0.6262152194976807},{"id":"https://openalex.org/C2779489039","wikidata":"https://www.wikidata.org/wiki/Q188121","display_name":"Staphylococcus aureus","level":3,"score":0.6218138933181763},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5529708862304688},{"id":"https://openalex.org/C2777949923","wikidata":"https://www.wikidata.org/wiki/Q131915","display_name":"Staphylococcus epidermidis","level":4,"score":0.47291263937950134},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.4683854877948761},{"id":"https://openalex.org/C2779812621","wikidata":"https://www.wikidata.org/wiki/Q258328","display_name":"Ear canal","level":2,"score":0.46201884746551514},{"id":"https://openalex.org/C2779288629","wikidata":"https://www.wikidata.org/wiki/Q199695","display_name":"Staphylococcus","level":4,"score":0.45019838213920593},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.4269486665725708},{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.42047038674354553},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.41736796498298645},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.3930400609970093},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1970507800579071},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.19300860166549683},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.13433101773262024},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.051066964864730835},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.37219/2528-8253-2021-5-55","doi":"https://doi.org/10.37219/2528-8253-2021-5-55","is_oa":true,"landing_page_url":"https://doi.org/10.37219/2528-8253-2021-5-55","pdf_url":"http://www.lorlife.kiev.ua/2021/2021_5_55.pdf","source":{"id":"https://openalex.org/S4210232859","display_name":"OTORHINOLARYNGOLOGY","issn_l":"2528-8245","issn":["2528-8245","2528-8253"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"OTORHINOLARYNGOLOGY","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.37219/2528-8253-2021-5-55","doi":"https://doi.org/10.37219/2528-8253-2021-5-55","is_oa":true,"landing_page_url":"https://doi.org/10.37219/2528-8253-2021-5-55","pdf_url":"http://www.lorlife.kiev.ua/2021/2021_5_55.pdf","source":{"id":"https://openalex.org/S4210232859","display_name":"OTORHINOLARYNGOLOGY","issn_l":"2528-8245","issn":["2528-8245","2528-8253"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"OTORHINOLARYNGOLOGY","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4200609060.pdf","grobid_xml":"https://content.openalex.org/works/W4200609060.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2409061829","https://openalex.org/W2314152643","https://openalex.org/W2411563969","https://openalex.org/W7215588369","https://openalex.org/W4385424597","https://openalex.org/W4206029521","https://openalex.org/W2051081446","https://openalex.org/W1969820574","https://openalex.org/W3183242534","https://openalex.org/W7116089994"],"abstract_inverted_index":{"Introduction:":[0],"Acute":[1],"diffuse":[2,82,102,161,228],"otitis":[3,56,83,103,162,206,229,265],"externa":[4,57,84,104,230],"is":[5,20,37,60,172],"a":[6,261],"spread":[7],"skin":[8],"inflammation":[9],"of":[10,15,25,32,55,61,66,73,89,109,121,131,144,157,159,182,195,205,209,233,256,264],"the":[11,16,43,52,74,110,155,234],"external":[12,111],"ear":[13,112],"canal":[14,113],"bacterial":[17,53],"origin.":[18],"It":[19],"reported":[21,173,191],"at":[22],"an":[23],"incidence":[24],"up":[26],"to":[27,39,77,133,203,254],"10%":[28],"among":[29],"healthy":[30],"population":[31,236],"all":[33],"age":[34],"groups.":[35],"Treatment":[36],"known":[38],"be":[40],"based":[41],"on":[42],"empirical":[44],"approach":[45],"for":[46,128],"prescribing":[47],"topical":[48],"antibacterials.":[49],"Therefore":[50],"studying":[51],"spectrum":[54,80],"causative":[58],"agents":[59],"great":[62],"value":[63],"in":[64,81,85,168,174,179,192,198,226,231],"terms":[65],"relevant":[67,119,170],"antimicrobial":[68],"therapy.":[69],"Aim:":[70],"The":[71],"objective":[72],"study":[75],"was":[76,115],"evaluate":[78],"microbial":[79,224],"patients":[86,232],"\u2013":[87],"residents":[88],"Ukraine.":[90],"Materials":[91],"and":[92,96,117,136,152,176,213,240],"methods:":[93],"Four":[94],"hundred":[95],"ninety-three":[97],"out-patients":[98],"diagnosed":[99],"with":[100,165],"acute":[101,160,227],"were":[105,125,139,147,189,217],"enrolled.":[106],"Microbial":[107],"composition":[108],"microflora":[114],"tested":[116],"aetiologically":[118,141,149,169,220],"titres":[120,130,143,171],"colony-forming":[122],"units":[123],"(CFU)":[124],"determined.":[126],"Criteria":[127],"evaluation:":[129],"104":[132],"106":[134],"CFU":[135,138,146],">106":[137],"considered":[140,148],"relevant.":[142],"<104":[145],"nonrelevant.":[150],"Results":[151],"discussion:":[153],"In":[154],"majority":[156],"cases":[158],"externa,":[163],"infection":[164,184],"Staphylococcus":[166,214,238],"aureus":[167,239],"53.2%":[175],"Pseudomonas":[177,241],"aeruginosa":[178],"23.6%.":[180],"Cases":[181],"multimicrobial":[183],"predominantly":[185,245],"involving":[186,246],"Gram-negative":[187,247],"flora":[188],"also":[190],"27.9%;":[193],"each":[194],"them":[196],"results":[197],"no":[199],"more":[200],"than":[201],"2":[202,253],"3%":[204,255],"externa.":[207,266],"Titres":[208],"Candida":[210],"spp.":[211],"(3.2%)":[212],"epidermidis":[215],"(2.6%)":[216],"measured":[218],"as":[219],"non-relevant.":[221],"Conclusion:":[222],"common":[223],"pathogens":[225],"Ukrainian":[235],"are":[237,260],"aeruginosa.":[242],"Multimicrobial":[243],"associations":[244],"flora,":[248],"which":[249],"do":[250],"not":[251],"exceed":[252],"cases.":[257],"Fungal":[258],"infections":[259],"rare":[262],"cause":[263]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":1}],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2021-12-31T00:00:00"}