{"id":"https://openalex.org/W4200577833","doi":"https://doi.org/10.32677/ijcr.v7i11.3107","title":"Combination therapy of omalizumab with house dust mite immunotherapy in chronic spontaneous urticaria associated with sensitization to dust mites-case series","display_name":"Combination therapy of omalizumab with house dust mite immunotherapy in chronic spontaneous urticaria associated with sensitization to dust mites-case series","publication_year":2021,"publication_date":"2021-12-18","ids":{"openalex":"https://openalex.org/W4200577833","doi":"https://doi.org/10.32677/ijcr.v7i11.3107"},"language":"en","primary_location":{"id":"doi:10.32677/ijcr.v7i11.3107","doi":"https://doi.org/10.32677/ijcr.v7i11.3107","is_oa":true,"landing_page_url":"https://doi.org/10.32677/ijcr.v7i11.3107","pdf_url":"https://mansapublishers.com/index.php/ijcr/article/download/3107/2532","source":{"id":"https://openalex.org/S2764668775","display_name":"Indian Journal of Case Reports","issn_l":"2454-129X","issn":["2454-129X","2454-1303"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indian Journal of Case Reports","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://mansapublishers.com/index.php/ijcr/article/download/3107/2532","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002547797","display_name":"Pooran Chand Kathuria","orcid":"https://orcid.org/0000-0002-6053-5192","observed_orcids":["https://orcid.org/0000-0002-6053-5192"]},"institutions":[{"id":"https://openalex.org/I4210122912","display_name":"BLK Super Speciality Hospital","ror":"https://ror.org/03tjs3938","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210122912"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"P C Kathuria","raw_affiliation_strings":["Department of Allergy and Asthma National Allergy Center, BLK Super Speciality Center, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Allergy and Asthma National Allergy Center, BLK Super Speciality Center, New Delhi, India","institution_ids":["https://openalex.org/I4210122912"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059257848","display_name":"Manisha Rai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210122912","display_name":"BLK Super Speciality Hospital","ror":"https://ror.org/03tjs3938","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210122912"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Manisha Rai","raw_affiliation_strings":["Associate Consultant, Department of Allergy and Asthma National Allergy Center, BLK Super Speciality Hospital, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Associate Consultant, Department of Allergy and Asthma National Allergy Center, BLK Super Speciality Hospital, New Delhi, India","institution_ids":["https://openalex.org/I4210122912"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5002547797"],"corresponding_institution_ids":["https://openalex.org/I4210122912"],"apc_list":null,"apc_paid":null,"fwci":0.2258,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.45709337,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":null,"issue":null,"first_page":"469","last_page":"472"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12438","display_name":"Urticaria and Related Conditions","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12438","display_name":"Urticaria and Related Conditions","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11346","display_name":"Mast cells and histamine","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10837","display_name":"Dermatology and Skin Diseases","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-spontaneous-urticaria","display_name":"chronic spontaneous urticaria","score":0.9860000014305115},{"id":"https://openalex.org/keywords/omalizumab","display_name":"omalizumab","score":1.0},{"id":"https://openalex.org/keywords/combination-therapy","display_name":"combination therapy","score":0.7369999885559082},{"id":"https://openalex.org/keywords/dermatophagoides-pteronyssinus","display_name":"Dermatophagoides pteronyssinus","score":0.9120000004768372},{"id":"https://openalex.org/keywords/dermatophagoides-farinae","display_name":"Dermatophagoides farinae","score":1.0},{"id":"https://openalex.org/keywords/allergic-rhinitis","display_name":"allergic rhinitis","score":0.7480000257492065},{"id":"https://openalex.org/keywords/asthma","display_name":"asthma","score":0.8600000143051147},{"id":"https://openalex.org/keywords/anti-ige-therapy","display_name":"anti-IgE therapy","score":0.7369999885559082},{"id":"https://openalex.org/keywords/urticaria-activity-score","display_name":"urticaria activity score","score":0.6990000009536743}],"concepts":[{"id":"https://openalex.org/C2778564945","wikidata":"https://www.wikidata.org/wiki/Q415392","display_name":"Omalizumab","level":4,"score":0.9600179195404053},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9537242650985718},{"id":"https://openalex.org/C2778715236","wikidata":"https://www.wikidata.org/wiki/Q55622662","display_name":"Discontinuation","level":2,"score":0.7617448568344116},{"id":"https://openalex.org/C2777995640","wikidata":"https://www.wikidata.org/wiki/Q1129007","display_name":"Angioedema","level":2,"score":0.6115097403526306},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.6050992012023926},{"id":"https://openalex.org/C2779384505","wikidata":"https://www.wikidata.org/wiki/Q17007513","display_name":"Concomitant","level":2,"score":0.5948098301887512},{"id":"https://openalex.org/C2776217527","wikidata":"https://www.wikidata.org/wiki/Q944828","display_name":"Sensitization","level":2,"score":0.5444974899291992},{"id":"https://openalex.org/C2778166374","wikidata":"https://www.wikidata.org/wiki/Q29938","display_name":"House dust mite","level":4,"score":0.5356763005256653},{"id":"https://openalex.org/C3017745231","wikidata":"https://www.wikidata.org/wiki/Q187440","display_name":"Chronic urticaria","level":2,"score":0.5081787109375},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4463271498680115},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.43169671297073364},{"id":"https://openalex.org/C141105273","wikidata":"https://www.wikidata.org/wiki/Q79455","display_name":"Immunoglobulin E","level":3,"score":0.3562541902065277},{"id":"https://openalex.org/C207480886","wikidata":"https://www.wikidata.org/wiki/Q42982","display_name":"Allergy","level":2,"score":0.3465886116027832},{"id":"https://openalex.org/C2780510475","wikidata":"https://www.wikidata.org/wiki/Q186752","display_name":"Allergen","level":3,"score":0.3344036936759949},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.3025287389755249},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2646251618862152},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.13010069727897644}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.32677/ijcr.v7i11.3107","doi":"https://doi.org/10.32677/ijcr.v7i11.3107","is_oa":true,"landing_page_url":"https://doi.org/10.32677/ijcr.v7i11.3107","pdf_url":"https://mansapublishers.com/index.php/ijcr/article/download/3107/2532","source":{"id":"https://openalex.org/S2764668775","display_name":"Indian Journal of Case Reports","issn_l":"2454-129X","issn":["2454-129X","2454-1303"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indian Journal of Case Reports","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.32677/ijcr.v7i11.3107","doi":"https://doi.org/10.32677/ijcr.v7i11.3107","is_oa":true,"landing_page_url":"https://doi.org/10.32677/ijcr.v7i11.3107","pdf_url":"https://mansapublishers.com/index.php/ijcr/article/download/3107/2532","source":{"id":"https://openalex.org/S2764668775","display_name":"Indian Journal of Case Reports","issn_l":"2454-129X","issn":["2454-129X","2454-1303"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indian Journal of Case Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4200577833.pdf","grobid_xml":"https://content.openalex.org/works/W4200577833.grobid-xml"},"referenced_works_count":13,"referenced_works":["https://openalex.org/W2072409428","https://openalex.org/W2112559420","https://openalex.org/W2461151789","https://openalex.org/W2562890785","https://openalex.org/W2619183589","https://openalex.org/W2763782620","https://openalex.org/W2767568586","https://openalex.org/W2790269034","https://openalex.org/W2793609975","https://openalex.org/W2964408428","https://openalex.org/W3047456285","https://openalex.org/W3088260167","https://openalex.org/W3190713584"],"related_works":["https://openalex.org/W4390016219","https://openalex.org/W2766223595","https://openalex.org/W2918343143","https://openalex.org/W6948095143","https://openalex.org/W2901431843","https://openalex.org/W3047456285","https://openalex.org/W2725447792","https://openalex.org/W3046993774","https://openalex.org/W2170610796","https://openalex.org/W2336901012"],"abstract_inverted_index":{"Chronic":[0],"spontaneous":[1],"urticaria":[2],"(CSU)":[3],"is":[4,18],"a":[5,41],"heterogeneous":[6],"disorder":[7],"with":[8,85],"recurrent":[9],"pruritic":[10],"wheals":[11],"and/or":[12],"angioedema.":[13],"The":[14],"anti-immunoglobulin":[15],"E":[16],"(omalizumab)":[17],"used":[19],"in":[20,77,128],"CSU":[21],"patients":[22],"resistant":[23],"to":[24,62,117],"four-fold":[25],"second-generation":[26],"anti-histamines.":[27],"Most":[28],"clinical":[29,119],"trials":[30],"have":[31,57],"experienced":[32],"relapse":[33],"after":[34,102],"stopping":[35],"omalizumab":[36,84],"treatment.":[37],"Here,":[38],"we":[39],"present":[40],"case":[42],"series":[43],"of":[44,47,83,104,125],"five":[45],"cases":[46,79],"chronic":[48],"atopic":[49],"urticarial":[50],"concomitant":[51],"allergic":[52],"rhinitis":[53],"and":[54,65,93,122],"asthma":[55],"which":[56],"shown":[58],"immunologically":[59],"significant":[60],"positivity":[61],"Dermatophagoides":[63,66],"pteronyssinus":[64],"farinae.":[67],"Disease":[68],"control":[69,127],"was":[70],"achieved":[71],"(Urticaria":[72],"Activity":[73],"Score":[74],"7":[75],"<6)":[76],"four":[78],"by":[80],"combination":[81],"therapy":[82,114],"house":[86],"dust":[87],"mite":[88],"(HDM)":[89],"Allergen":[90],"Immunotherapy":[91],"(AIT)":[92],"remained":[94],"sustained":[95],"for":[96,106],"three":[97],"years":[98],"on":[99],"follow-up":[100],"even":[101],"discontinuation":[103],"AIT":[105],"one":[107],"year.":[108],"We":[109],"hypothesize":[110],"that":[111],"this":[112],"combined":[113],"may":[115],"contribute":[116],"enhanced":[118],"efficacy,":[120],"safety,":[121],"faster":[123],"achievement":[124],"disease":[126],"CSU.":[129]},"counts_by_year":[{"year":2022,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2021-12-31T00:00:00"}