{"id":"https://openalex.org/W4200535854","doi":"https://doi.org/10.3390/jcm10245855","title":"Effects of Thyroid Hormone on Tissue Hypoxia: Relevance to Sepsis Therapy","display_name":"Effects of Thyroid Hormone on Tissue Hypoxia: Relevance to Sepsis Therapy","publication_year":2021,"publication_date":"2021-12-14","ids":{"openalex":"https://openalex.org/W4200535854","doi":"https://doi.org/10.3390/jcm10245855","pmid":"https://pubmed.ncbi.nlm.nih.gov/34945151","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8703810"},"language":"en","primary_location":{"id":"doi:10.3390/jcm10245855","doi":"https://doi.org/10.3390/jcm10245855","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jcm10245855","pdf_url":"https://www.mdpi.com/2077-0383/10/24/5855/pdf?version=1639531519","source":{"id":"https://openalex.org/S2737969411","display_name":"Journal of Clinical Medicine","issn_l":"2077-0383","issn":["2077-0383"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Medicine","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2077-0383/10/24/5855/pdf?version=1639531519","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064361318","display_name":"Athanasios I. Lourbopoulos","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I200777214","display_name":"National and Kapodistrian University of Athens","ror":"https://ror.org/04gnjpq42","country_code":"GR","type":"education","lineage":["https://openalex.org/I200777214"]},{"id":"https://openalex.org/I4210146811","display_name":"Sch\u00f6n Klinik Bad Aibling","ror":"https://ror.org/04fr6kc62","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210088209","https://openalex.org/I4210146811"]},{"id":"https://openalex.org/I4405259612","display_name":"Institut f\u00fcr Schlaganfall- und Demenzforschung","ror":"https://ror.org/02fa5cb34","country_code":"DE","type":"education","lineage":["https://openalex.org/I3018771216","https://openalex.org/I4405259612","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I8204097","display_name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","ror":"https://ror.org/05591te55","country_code":"DE","type":"education","lineage":["https://openalex.org/I8204097"]}],"countries":["DE","GR"],"is_corresponding":false,"raw_author_name":"Athanasios I. Lourbopoulos","raw_affiliation_strings":["Department of Pharmacology, National and Kapodistrian University of Athens, 75 Mikras Asias Ave, Goudi, 11527 Athens, Greece","Institute for Stroke and Dementia Research (ISD), University of Munich Medical Center, 81377 Munich, Germany","Neurointensive Care Unit, Schoen Klinik Bad Aibling, Kolbermoorerstrasse 72, 83043 Bad Aibling, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, National and Kapodistrian University of Athens, 75 Mikras Asias Ave, Goudi, 11527 Athens, Greece","institution_ids":["https://openalex.org/I200777214"]},{"raw_affiliation_string":"Institute for Stroke and Dementia Research (ISD), University of Munich Medical Center, 81377 Munich, Germany","institution_ids":["https://openalex.org/I4405259612","https://openalex.org/I8204097"]},{"raw_affiliation_string":"Neurointensive Care Unit, Schoen Klinik Bad Aibling, Kolbermoorerstrasse 72, 83043 Bad Aibling, Germany","institution_ids":["https://openalex.org/I4210146811"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031030486","display_name":"Iordanis S. Mourouzis","orcid":"https://orcid.org/0000-0002-9670-5886","observed_orcids":["https://orcid.org/0000-0002-9670-5886"]},"institutions":[{"id":"https://openalex.org/I200777214","display_name":"National and Kapodistrian University of Athens","ror":"https://ror.org/04gnjpq42","country_code":"GR","type":"education","lineage":["https://openalex.org/I200777214"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Iordanis S. Mourouzis","raw_affiliation_strings":["Department of Pharmacology, National and Kapodistrian University of Athens, 75 Mikras Asias Ave, Goudi, 11527 Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, National and Kapodistrian University of Athens, 75 Mikras Asias Ave, Goudi, 11527 Athens, Greece","institution_ids":["https://openalex.org/I200777214"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080568142","display_name":"Athanasios G. Trikas","orcid":"https://orcid.org/0000-0003-4367-805X","observed_orcids":["https://orcid.org/0000-0003-4367-805X"]},"institutions":[{"id":"https://openalex.org/I200777214","display_name":"National and Kapodistrian University of Athens","ror":"https://ror.org/04gnjpq42","country_code":"GR","type":"education","lineage":["https://openalex.org/I200777214"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Athanasios G. Trikas","raw_affiliation_strings":["Department of Pharmacology, National and Kapodistrian University of Athens, 75 Mikras Asias Ave, Goudi, 11527 Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, National and Kapodistrian University of Athens, 75 Mikras Asias Ave, Goudi, 11527 Athens, Greece","institution_ids":["https://openalex.org/I200777214"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025901453","display_name":"Ioulia K. Tseti","orcid":"https://orcid.org/0000-0002-4734-579X","observed_orcids":["https://orcid.org/0000-0002-4734-579X"]},"institutions":[{"id":"https://openalex.org/I200777214","display_name":"National and Kapodistrian University of Athens","ror":"https://ror.org/04gnjpq42","country_code":"GR","type":"education","lineage":["https://openalex.org/I200777214"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Ioulia K. Tseti","raw_affiliation_strings":["Department of Pharmacology, National and Kapodistrian University of Athens, 75 Mikras Asias Ave, Goudi, 11527 Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, National and Kapodistrian University of Athens, 75 Mikras Asias Ave, Goudi, 11527 Athens, Greece","institution_ids":["https://openalex.org/I200777214"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5069616636","display_name":"Constantinos I. Pantos","orcid":"https://orcid.org/0000-0003-2449-0991","observed_orcids":["https://orcid.org/0000-0003-2449-0991"]},"institutions":[{"id":"https://openalex.org/I200777214","display_name":"National and Kapodistrian University of Athens","ror":"https://ror.org/04gnjpq42","country_code":"GR","type":"education","lineage":["https://openalex.org/I200777214"]}],"countries":["GR"],"is_corresponding":true,"raw_author_name":"Constantinos I. Pantos","raw_affiliation_strings":["Department of Pharmacology, National and Kapodistrian University of Athens, 75 Mikras Asias Ave, Goudi, 11527 Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, National and Kapodistrian University of Athens, 75 Mikras Asias Ave, Goudi, 11527 Athens, Greece","institution_ids":["https://openalex.org/I200777214"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5069616636"],"corresponding_institution_ids":["https://openalex.org/I200777214"],"apc_list":{"value":2200,"currency":"CHF","value_usd":2376},"apc_paid":{"value":2200,"currency":"CHF","value_usd":2376},"fwci":0.7291,"has_fulltext":true,"cited_by_count":30,"citation_normalized_percentile":{"value":0.60861473,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"10","issue":"24","first_page":"5855","last_page":"5855"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.6226000189781189,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.6226000189781189,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.3386000096797943,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14165","display_name":"Inflammation biomarkers and pathways","score":0.0032999999821186066,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/thyroid-hormones","display_name":"thyroid hormones","score":0.9980000257492065},{"id":"https://openalex.org/keywords/tissue-hypoxia","display_name":"tissue hypoxia","score":0.9340000152587891},{"id":"https://openalex.org/keywords/sepsis","display_name":"sepsis","score":0.9750000238418579},{"id":"https://openalex.org/keywords/triiodothyronine","display_name":"triiodothyronine","score":0.9150000214576721},{"id":"https://openalex.org/keywords/organ-failure","display_name":"organ failure","score":0.5249999761581421},{"id":"https://openalex.org/keywords/myocardial-infarction","display_name":"myocardial infarction","score":0.8889999985694885},{"id":"https://openalex.org/keywords/tissue-remodeling","display_name":"tissue remodeling","score":0.6600000262260437},{"id":"https://openalex.org/keywords/angiogenesis","display_name":"angiogenesis","score":0.7509999871253967},{"id":"https://openalex.org/keywords/mitochondrial-biogenesis","display_name":"mitochondrial biogenesis","score":0.984000027179718},{"id":"https://openalex.org/keywords/cardiac-repair","display_name":"cardiac repair","score":0.5450000166893005},{"id":"https://openalex.org/keywords/organogenesis","display_name":"organogenesis","score":0.3709999918937683}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.79962557554245},{"id":"https://openalex.org/C7836513","wikidata":"https://www.wikidata.org/wiki/Q1641506","display_name":"Hypoxia (environmental)","level":3,"score":0.7545703649520874},{"id":"https://openalex.org/C2778384902","wikidata":"https://www.wikidata.org/wiki/Q183134","display_name":"Sepsis","level":2,"score":0.5997676849365234},{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.4944798946380615},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.4768180251121521},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.4457698464393616},{"id":"https://openalex.org/C526584372","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid","level":2,"score":0.43550431728363037},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.36973458528518677},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3447258472442627},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3421822786331177},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.15446242690086365},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3390/jcm10245855","doi":"https://doi.org/10.3390/jcm10245855","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jcm10245855","pdf_url":"https://www.mdpi.com/2077-0383/10/24/5855/pdf?version=1639531519","source":{"id":"https://openalex.org/S2737969411","display_name":"Journal of Clinical Medicine","issn_l":"2077-0383","issn":["2077-0383"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Medicine","raw_type":"journal-article"},{"id":"pmid:34945151","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34945151","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of clinical medicine","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8703810","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8703810/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Clin Med","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:c83463d10ec749f0bc7fca31aee617ff","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/c83463d10ec749f0bc7fca31aee617ff","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Clinical Medicine, Vol 10, Iss 5855, p 5855 (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/jcm10245855","doi":"https://doi.org/10.3390/jcm10245855","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jcm10245855","pdf_url":"https://www.mdpi.com/2077-0383/10/24/5855/pdf?version=1639531519","source":{"id":"https://openalex.org/S2737969411","display_name":"Journal of Clinical Medicine","issn_l":"2077-0383","issn":["2077-0383"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.979200005531311,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4200535854.pdf","grobid_xml":"https://content.openalex.org/works/W4200535854.grobid-xml"},"referenced_works_count":157,"referenced_works":["https://openalex.org/W6265656","https://openalex.org/W1503255269","https://openalex.org/W1512456078","https://openalex.org/W1514957492","https://openalex.org/W1518607321","https://openalex.org/W1533901948","https://openalex.org/W1540878808","https://openalex.org/W1541671351","https://openalex.org/W1593118353","https://openalex.org/W1824273378","https://openalex.org/W1836591545","https://openalex.org/W1838882977","https://openalex.org/W1963631663","https://openalex.org/W1970118835","https://openalex.org/W1971907225","https://openalex.org/W1974913841","https://openalex.org/W1980633206","https://openalex.org/W1984924011","https://openalex.org/W1985047970","https://openalex.org/W1986458649","https://openalex.org/W1987135328","https://openalex.org/W1987475341","https://openalex.org/W1990385348","https://openalex.org/W1990877858","https://openalex.org/W1991535596","https://openalex.org/W1991654724","https://openalex.org/W1991917774","https://openalex.org/W1995656522","https://openalex.org/W1996476040","https://openalex.org/W1998652199","https://openalex.org/W1999277186","https://openalex.org/W2000461166","https://openalex.org/W2000785864","https://openalex.org/W2008605540","https://openalex.org/W2011021796","https://openalex.org/W2016227264","https://openalex.org/W2019131650","https://openalex.org/W2021741127","https://openalex.org/W2022014090","https://openalex.org/W2022896133","https://openalex.org/W2024208569","https://openalex.org/W2033553696","https://openalex.org/W2034720207","https://openalex.org/W2038424092","https://openalex.org/W2038474826","https://openalex.org/W2040960321","https://openalex.org/W2041093510","https://openalex.org/W2043987331","https://openalex.org/W2048478083","https://openalex.org/W2051683103","https://openalex.org/W2053353132","https://openalex.org/W2056193118","https://openalex.org/W2061170810","https://openalex.org/W2063996616","https://openalex.org/W2065907781","https://openalex.org/W2067677232","https://openalex.org/W2068561864","https://openalex.org/W2073791430","https://openalex.org/W2074027154","https://openalex.org/W2079749507","https://openalex.org/W2082088375","https://openalex.org/W2083786523","https://openalex.org/W2088497069","https://openalex.org/W2092427927","https://openalex.org/W2095609107","https://openalex.org/W2103440521","https://openalex.org/W2104549320","https://openalex.org/W2106074626","https://openalex.org/W2106445989","https://openalex.org/W2106597930","https://openalex.org/W2110726707","https://openalex.org/W2111181406","https://openalex.org/W2112669811","https://openalex.org/W2113740320","https://openalex.org/W2117286082","https://openalex.org/W2119606192","https://openalex.org/W2121412391","https://openalex.org/W2128703021","https://openalex.org/W2128933624","https://openalex.org/W2139382725","https://openalex.org/W2140653277","https://openalex.org/W2141789735","https://openalex.org/W2143001271","https://openalex.org/W2145679331","https://openalex.org/W2146249722","https://openalex.org/W2149848093","https://openalex.org/W2150702956","https://openalex.org/W2151053125","https://openalex.org/W2158623850","https://openalex.org/W2165821124","https://openalex.org/W2166839888","https://openalex.org/W2168528745","https://openalex.org/W2168760648","https://openalex.org/W2169010806","https://openalex.org/W2181632327","https://openalex.org/W2193836911","https://openalex.org/W2232568689","https://openalex.org/W2280404143","https://openalex.org/W2315680417","https://openalex.org/W2317811592","https://openalex.org/W2347111943","https://openalex.org/W2519320742","https://openalex.org/W2537831565","https://openalex.org/W2573595336","https://openalex.org/W2581541649","https://openalex.org/W2592879615","https://openalex.org/W2618592485","https://openalex.org/W2732932829","https://openalex.org/W2739478490","https://openalex.org/W2740234011","https://openalex.org/W2765834203","https://openalex.org/W2766326437","https://openalex.org/W2784584122","https://openalex.org/W2808829764","https://openalex.org/W2808871246","https://openalex.org/W2811073355","https://openalex.org/W2823725159","https://openalex.org/W2886665216","https://openalex.org/W2889106114","https://openalex.org/W2889905654","https://openalex.org/W2890220331","https://openalex.org/W2892299602","https://openalex.org/W2894422883","https://openalex.org/W2894620939","https://openalex.org/W2915952373","https://openalex.org/W2944021900","https://openalex.org/W2944974725","https://openalex.org/W2947985436","https://openalex.org/W2948057680","https://openalex.org/W2950944645","https://openalex.org/W2980715244","https://openalex.org/W2981179286","https://openalex.org/W2982128093","https://openalex.org/W2992163200","https://openalex.org/W2995721821","https://openalex.org/W2997658791","https://openalex.org/W2998334852","https://openalex.org/W3000951314","https://openalex.org/W3001653173","https://openalex.org/W3008170328","https://openalex.org/W3012116029","https://openalex.org/W3012781727","https://openalex.org/W3016555942","https://openalex.org/W3016771699","https://openalex.org/W3019780995","https://openalex.org/W3037549222","https://openalex.org/W3038125282","https://openalex.org/W3096262333","https://openalex.org/W3097886965","https://openalex.org/W3108425280","https://openalex.org/W3121364493","https://openalex.org/W3124007560","https://openalex.org/W3132976462","https://openalex.org/W3150643341","https://openalex.org/W3166826773","https://openalex.org/W3213870443","https://openalex.org/W6769780035"],"related_works":["https://openalex.org/W3150643341","https://openalex.org/W4239739305","https://openalex.org/W2320596054","https://openalex.org/W2039355952","https://openalex.org/W2148744617","https://openalex.org/W2588376575","https://openalex.org/W2070174022","https://openalex.org/W18850492","https://openalex.org/W4252442701","https://openalex.org/W2026274357"],"abstract_inverted_index":{"Tissue":[0],"hypoxia":[1,128,152],"occurs":[2],"in":[3,32,102,150],"various":[4],"conditions":[5],"such":[6],"as":[7],"myocardial":[8,107],"or":[9],"brain":[10],"ischemia":[11],"and":[12,15,17,21,43,80,109],"infarction,":[13],"sepsis,":[14],"trauma,":[16],"induces":[18],"cellular":[19],"damage":[20],"tissue":[22,104,127,151],"remodeling":[23,105,112],"with":[24,131,155],"recapitulation":[25],"of":[26,59,75,88,113,148],"fetal-like":[27],"reprogramming,":[28],"which":[29,51,70],"eventually":[30],"results":[31],"organ":[33,54,76,161],"failure.":[34,162],"Analogies":[35],"seem":[36],"to":[37,158],"exist":[38],"between":[39,140],"the":[40,114,156],"damaged":[41],"hypoxic":[42,103],"developing":[44],"organs,":[45],"indicating":[46],"that":[47,122],"a":[48,72,145],"regulatory":[49],"network":[50],"drives":[52],"embryonic":[53],"development":[55],"may":[56,86],"control":[57],"aspects":[58],"heart":[60],"(or":[61],"tissue)":[62],"repair.":[63],"In":[64],"this":[65],"context,":[66],"thyroid":[67],"hormone":[68],"(TH),":[69],"is":[71],"critical":[73],"regulator":[74],"maturation,":[77],"physiologic":[78],"angiogenesis,":[79],"mitochondrial":[81],"biogenesis":[82],"during":[83,129],"fetal":[84,95],"development,":[85],"be":[87],"important":[89,132],"physiological":[90,133],"relevance":[91],"upon":[92],"stress":[93],"(hypoxia)-induced":[94],"reprogramming.":[96],"TH":[97,149],"signaling":[98],"has":[99],"been":[100],"implicated":[101],"after":[106,153],"infarction":[108],"T3":[110,123],"prevents":[111],"postinfarcted":[115],"heart.":[116],"Similarly,":[117],"preliminary":[118],"experimental":[119],"evidence":[120],"suggests":[121],"can":[124],"prevent":[125],"early":[126],"sepsis":[130,154],"consequences.":[134],"Thus,":[135],"based":[136],"on":[137],"common":[138],"pathways":[139],"different":[141],"paradigms,":[142],"we":[143],"propose":[144],"possible":[146],"role":[147],"potential":[157],"reduce":[159],"secondary":[160]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":4}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2021-12-31T00:00:00"}
