{"id":"https://openalex.org/W4200525487","doi":"https://doi.org/10.1208/s12249-021-02197-2","title":"Scrutinizing the Feasibility of Nonionic Surfactants to Form Isotropic Bicelles of Curcumin: a Potential Antiviral Candidate Against COVID-19","display_name":"Scrutinizing the Feasibility of Nonionic Surfactants to Form Isotropic Bicelles of Curcumin: a Potential Antiviral Candidate Against COVID-19","publication_year":2021,"publication_date":"2021-12-29","ids":{"openalex":"https://openalex.org/W4200525487","doi":"https://doi.org/10.1208/s12249-021-02197-2","pmid":"https://pubmed.ncbi.nlm.nih.gov/34966978","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8716085"},"language":"en","primary_location":{"id":"doi:10.1208/s12249-021-02197-2","doi":"https://doi.org/10.1208/s12249-021-02197-2","is_oa":true,"landing_page_url":"https://doi.org/10.1208/s12249-021-02197-2","pdf_url":"https://link.springer.com/content/pdf/10.1208/s12249-021-02197-2.pdf","source":{"id":"https://openalex.org/S1234972","display_name":"AAPS PharmSciTech","issn_l":"1530-9932","issn":["1530-9932"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AAPS PharmSciTech","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","datacite","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1208/s12249-021-02197-2.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032338757","display_name":"Dina Bahaa El Din Mahmoud","orcid":"https://orcid.org/0000-0001-6554-4250","observed_orcids":["https://orcid.org/0000-0001-6554-4250"]},"institutions":[{"id":"https://openalex.org/I4210136593","display_name":"National Organization for Drug Control and Research","ror":"https://ror.org/0407ex783","country_code":"EG","type":"facility","lineage":["https://openalex.org/I4210136593","https://openalex.org/I4210160667","https://openalex.org/I4405259620"]},{"id":"https://openalex.org/I4405259620","display_name":"Egyptian Drug Authority","ror":"https://ror.org/02ff43k45","country_code":"EG","type":"government","lineage":["https://openalex.org/I4210160667","https://openalex.org/I4405259620"]},{"id":"https://openalex.org/I926574661","display_name":"Leipzig University","ror":"https://ror.org/03s7gtk40","country_code":"DE","type":"education","lineage":["https://openalex.org/I926574661"]}],"countries":["DE","EG"],"is_corresponding":true,"raw_author_name":"Dina B. Mahmoud","raw_affiliation_strings":["Department of Pharmaceutics, Egyptian drug Authority (formerly known as National Organization for Drug Control and Research), Giza, Egypt. Dina.BahaaElDinMahmoudZaki@medizin.uni-leipzig.de","Pharmaceutical Technology, Institute of Pharmacy, Leipzig University, 04317, Leipzig, Germany. Dina.BahaaElDinMahmoudZaki@medizin.uni-leipzig.de","Department of Pharmaceutics, Egyptian drug Authority (formerly known as National Organization for Drug Control and Research), Giza, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, Egyptian drug Authority (formerly known as National Organization for Drug Control and Research), Giza, Egypt. Dina.BahaaElDinMahmoudZaki@medizin.uni-leipzig.de","institution_ids":["https://openalex.org/I4210136593","https://openalex.org/I4405259620"]},{"raw_affiliation_string":"Pharmaceutical Technology, Institute of Pharmacy, Leipzig University, 04317, Leipzig, Germany. Dina.BahaaElDinMahmoudZaki@medizin.uni-leipzig.de","institution_ids":["https://openalex.org/I926574661"]},{"raw_affiliation_string":"Department of Pharmaceutics, Egyptian drug Authority (formerly known as National Organization for Drug Control and Research), Giza, Egypt","institution_ids":["https://openalex.org/I4210136593","https://openalex.org/I4405259620"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029036988","display_name":"Mohamed Mofreh Bakr","orcid":"https://orcid.org/0009-0007-1037-1058","observed_orcids":["https://orcid.org/0009-0007-1037-1058"]},"institutions":[{"id":"https://openalex.org/I4210136593","display_name":"National Organization for Drug Control and Research","ror":"https://ror.org/0407ex783","country_code":"EG","type":"facility","lineage":["https://openalex.org/I4210136593","https://openalex.org/I4210160667","https://openalex.org/I4405259620"]},{"id":"https://openalex.org/I4405259620","display_name":"Egyptian Drug Authority","ror":"https://ror.org/02ff43k45","country_code":"EG","type":"government","lineage":["https://openalex.org/I4210160667","https://openalex.org/I4405259620"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Mohamed Mofreh Bakr","raw_affiliation_strings":["Department of Pharmaceutics, Egyptian drug Authority (formerly known as National Organization for Drug Control and Research), Giza, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, Egyptian drug Authority (formerly known as National Organization for Drug Control and Research), Giza, Egypt","institution_ids":["https://openalex.org/I4210136593","https://openalex.org/I4405259620"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039517347","display_name":"Ahmed Ali Al-Karmalawy","orcid":"https://orcid.org/0000-0002-8173-6073","observed_orcids":["https://orcid.org/0000-0002-8173-6073"]},"institutions":[{"id":"https://openalex.org/I4405268078","display_name":"Horus University \u2013 Egypt","ror":"https://ror.org/05qh69251","country_code":"EG","type":"education","lineage":["https://openalex.org/I4405268078"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Ahmed A. Al-karmalawy","raw_affiliation_strings":["Department of Pharmaceutical Medicinal Chemistry, Faculty of Pharmacy, Horus University-Egypt, New Damietta, 34518, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Medicinal Chemistry, Faculty of Pharmacy, Horus University-Egypt, New Damietta, 34518, Egypt","institution_ids":["https://openalex.org/I4405268078"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015074295","display_name":"Yassmin Moatasim","orcid":"https://orcid.org/0000-0003-2159-2511","observed_orcids":["https://orcid.org/0000-0003-2159-2511"]},"institutions":[{"id":"https://openalex.org/I4210131959","display_name":"National Research Centre","ror":"https://ror.org/02n85j827","country_code":"EG","type":"facility","lineage":["https://openalex.org/I4210131959"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Yassmin Moatasim","raw_affiliation_strings":["Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, 12622, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, 12622, Egypt","institution_ids":["https://openalex.org/I4210131959"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Ahmed El Taweel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210131959","display_name":"National Research Centre","ror":"https://ror.org/02n85j827","country_code":"EG","type":"facility","lineage":["https://openalex.org/I4210131959"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Ahmed El Taweel","raw_affiliation_strings":["Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, 12622, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, 12622, Egypt","institution_ids":["https://openalex.org/I4210131959"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5107910392","display_name":"Ahmed Mostafa","orcid":"https://orcid.org/0000-0002-2878-5714","observed_orcids":["https://orcid.org/0000-0002-2878-5714"]},"institutions":[{"id":"https://openalex.org/I4210131959","display_name":"National Research Centre","ror":"https://ror.org/02n85j827","country_code":"EG","type":"facility","lineage":["https://openalex.org/I4210131959"]}],"countries":["EG"],"is_corresponding":true,"raw_author_name":"Ahmed Mostafa","raw_affiliation_strings":["Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, 12622, Egypt. ahmed_elsayed@daad-alumni.de","Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, 12622, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, 12622, Egypt. ahmed_elsayed@daad-alumni.de","institution_ids":["https://openalex.org/I4210131959"]},{"raw_affiliation_string":"Center of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, 12622, Egypt","institution_ids":["https://openalex.org/I4210131959"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5032338757","https://openalex.org/A5107910392"],"corresponding_institution_ids":["https://openalex.org/I4210131959","https://openalex.org/I4210136593","https://openalex.org/I4405259620","https://openalex.org/I926574661"],"apc_list":{"value":3280,"currency":"USD","value_usd":3280},"apc_paid":{"value":3280,"currency":"USD","value_usd":3280},"fwci":4.4615,"has_fulltext":true,"cited_by_count":63,"citation_normalized_percentile":{"value":0.96600291,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"23","issue":"1","first_page":"44","last_page":"44"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.7935000061988831,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.7935000061988831,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11319","display_name":"Curcumin's Biomedical Applications","score":0.12729999423027039,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.03150000050663948,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/curcumin","display_name":"curcumin","score":0.9900000095367432},{"id":"https://openalex.org/keywords/bicelles","display_name":"bicelles","score":0.9319999814033508},{"id":"https://openalex.org/keywords/nonionic-surfactants","display_name":"nonionic surfactants","score":0.9919999837875366},{"id":"https://openalex.org/keywords/oral-drug-delivery","display_name":"oral drug delivery","score":0.7649999856948853},{"id":"https://openalex.org/keywords/sars-cov-2","display_name":"SARS-CoV-2","score":0.8880000114440918},{"id":"https://openalex.org/keywords/antiviral-activity","display_name":"antiviral activity","score":0.8799999952316284},{"id":"https://openalex.org/keywords/covid-19","display_name":"COVID-19 pandemic","score":0.9100000262260437},{"id":"https://openalex.org/keywords/phosphatidylcholine","display_name":"phosphatidylcholine","score":0.8519999980926514},{"id":"https://openalex.org/keywords/labrasol","display_name":"Labrasol","score":0.7850000262260437},{"id":"https://openalex.org/keywords/tween-80","display_name":"Tween 80","score":0.9319999814033508},{"id":"https://openalex.org/keywords/cremophor-el","display_name":"Cremophor EL","score":0.875},{"id":"https://openalex.org/keywords/pluronic-f127","display_name":"Pluronic F127","score":0.9599999785423279},{"id":"https://openalex.org/keywords/mixed-micelles","display_name":"mixed micelles","score":0.8050000071525574},{"id":"https://openalex.org/keywords/drug-dissolution","display_name":"drug dissolution","score":0.671999990940094},{"id":"https://openalex.org/keywords/intestinal-permeation","display_name":"intestinal permeation","score":0.7559999823570251},{"id":"https://openalex.org/keywords/liposomes","display_name":"liposomes","score":0.7350000143051147},{"id":"https://openalex.org/keywords/hydrophobic-drug-delivery","display_name":"hydrophobic drug delivery","score":0.6980000138282776}],"concepts":[{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.6772044897079468},{"id":"https://openalex.org/C2778250585","wikidata":"https://www.wikidata.org/wiki/Q312266","display_name":"Curcumin","level":2,"score":0.6503243446350098},{"id":"https://openalex.org/C3007834351","wikidata":"https://www.wikidata.org/wiki/Q82069695","display_name":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","level":5,"score":0.552460253238678},{"id":"https://openalex.org/C3006700255","wikidata":"https://www.wikidata.org/wiki/Q81068910","display_name":"2019-20 coronavirus outbreak","level":3,"score":0.5136086940765381},{"id":"https://openalex.org/C63491327","wikidata":"https://www.wikidata.org/wiki/Q6888332","display_name":"Model lipid bilayer","level":5,"score":0.48147645592689514},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.47991785407066345},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.45507657527923584},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.2913225591182709},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.2594720125198364},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.16291657090187073},{"id":"https://openalex.org/C39944091","wikidata":"https://www.wikidata.org/wiki/Q423279","display_name":"Lipid bilayer","level":3,"score":0.1291712522506714},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.11116471886634827},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.07750710844993591},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.0},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0},{"id":"https://openalex.org/C116675565","wikidata":"https://www.wikidata.org/wiki/Q3241045","display_name":"Outbreak","level":2,"score":0.0},{"id":"https://openalex.org/C76564549","wikidata":"https://www.wikidata.org/wiki/Q17154515","display_name":"Lipid bilayer phase behavior","level":4,"score":0.0}],"mesh":[{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000998","descriptor_name":"Antiviral Agents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003474","descriptor_name":"Curcumin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005240","descriptor_name":"Feasibility Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008823","descriptor_name":"Micelles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013501","descriptor_name":"Surface-Active Agents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D062105","descriptor_name":"Molecular Docking Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1208/s12249-021-02197-2","doi":"https://doi.org/10.1208/s12249-021-02197-2","is_oa":true,"landing_page_url":"https://doi.org/10.1208/s12249-021-02197-2","pdf_url":"https://link.springer.com/content/pdf/10.1208/s12249-021-02197-2.pdf","source":{"id":"https://openalex.org/S1234972","display_name":"AAPS PharmSciTech","issn_l":"1530-9932","issn":["1530-9932"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AAPS PharmSciTech","raw_type":"journal-article"},{"id":"pmid:34966978","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34966978","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AAPS PharmSciTech","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8716085","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8716085/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AAPS PharmSciTech","raw_type":"Text"},{"id":"pmh:oai:frl.publisso.de:frl:6442692","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8716085","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8716085/pdf/12249_2021_Article_2197.pdf","source":{"id":"https://openalex.org/S4306402606","display_name":"Informationszentrum Lebenswissenschaften (ZB MED)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210112663","host_organization_name":"ZB MED - Information Centre for Life Sciences","host_organization_lineage":["https://openalex.org/I4210112663"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://lobid.org/resources/99370673930706441#!, 23(1):44","raw_type":"Zeitschriftenartikel"},{"id":"doi:10.60692/rtr0d-16w86","doi":"https://doi.org/10.60692/rtr0d-16w86","is_oa":true,"landing_page_url":"https://doi.org/10.60692/rtr0d-16w86","pdf_url":null,"source":{"id":"https://openalex.org/S7407051682","display_name":"Greater South Information System","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"},{"id":"doi:10.60692/z47jx-vc848","doi":"https://doi.org/10.60692/z47jx-vc848","is_oa":true,"landing_page_url":"https://doi.org/10.60692/z47jx-vc848","pdf_url":null,"source":{"id":"https://openalex.org/S7407051682","display_name":"Greater South Information System","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.1208/s12249-021-02197-2","doi":"https://doi.org/10.1208/s12249-021-02197-2","is_oa":true,"landing_page_url":"https://doi.org/10.1208/s12249-021-02197-2","pdf_url":"https://link.springer.com/content/pdf/10.1208/s12249-021-02197-2.pdf","source":{"id":"https://openalex.org/S1234972","display_name":"AAPS PharmSciTech","issn_l":"1530-9932","issn":["1530-9932"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AAPS PharmSciTech","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[{"id":"https://openalex.org/G7764292476","display_name":null,"funder_award_id":"MP120801","funder_id":"https://openalex.org/F4320310077","funder_display_name":"National Research Centre"}],"funders":[{"id":"https://openalex.org/F4320308269","display_name":"Alexander von Humboldt-Stiftung","ror":"https://ror.org/012kf4317"},{"id":"https://openalex.org/F4320310077","display_name":"National Research Centre","ror":"https://ror.org/02n85j827"},{"id":"https://openalex.org/F4320321653","display_name":"Ministry of Scientific Research, Egypt","ror":"https://ror.org/00k4cwq24"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4200525487.pdf","grobid_xml":"https://content.openalex.org/works/W4200525487.grobid-xml"},"referenced_works_count":57,"referenced_works":["https://openalex.org/W1782748178","https://openalex.org/W1972512637","https://openalex.org/W1980106504","https://openalex.org/W1988724588","https://openalex.org/W1991327193","https://openalex.org/W1998247886","https://openalex.org/W2000820845","https://openalex.org/W2008677452","https://openalex.org/W2017414822","https://openalex.org/W2034496890","https://openalex.org/W2036459378","https://openalex.org/W2040212384","https://openalex.org/W2051311750","https://openalex.org/W2053427743","https://openalex.org/W2058343111","https://openalex.org/W2066289545","https://openalex.org/W2072999689","https://openalex.org/W2084325913","https://openalex.org/W2102380386","https://openalex.org/W2107075698","https://openalex.org/W2124960092","https://openalex.org/W2145418093","https://openalex.org/W2166189591","https://openalex.org/W2312266417","https://openalex.org/W2316173461","https://openalex.org/W2320942212","https://openalex.org/W2346957939","https://openalex.org/W2437365889","https://openalex.org/W2613122048","https://openalex.org/W2633100912","https://openalex.org/W2751824563","https://openalex.org/W2782690276","https://openalex.org/W2787711470","https://openalex.org/W2887957443","https://openalex.org/W2892137180","https://openalex.org/W2897278401","https://openalex.org/W2902752800","https://openalex.org/W2903058058","https://openalex.org/W3010321971","https://openalex.org/W3014459093","https://openalex.org/W3021161255","https://openalex.org/W3021286799","https://openalex.org/W3023999991","https://openalex.org/W3030266358","https://openalex.org/W3034016291","https://openalex.org/W3040697567","https://openalex.org/W3041095625","https://openalex.org/W3082590213","https://openalex.org/W3084138061","https://openalex.org/W3086282643","https://openalex.org/W3102251445","https://openalex.org/W3109598707","https://openalex.org/W3122957710","https://openalex.org/W3124113186","https://openalex.org/W3134872449","https://openalex.org/W3135512914","https://openalex.org/W3138742900"],"related_works":["https://openalex.org/W4320918300","https://openalex.org/W4317830036","https://openalex.org/W4386530794","https://openalex.org/W4327814038","https://openalex.org/W4410005393","https://openalex.org/W2956049292","https://openalex.org/W2206163354","https://openalex.org/W4226373770","https://openalex.org/W4308770421","https://openalex.org/W4295958484"],"abstract_inverted_index":{"Abstract":[0],"Investigating":[1],"bicelles":[2,46,64,72,155,158,180],"as":[3,199],"an":[4,200],"oral":[5,162],"drug":[6,130,146,171],"delivery":[7,163],"system":[8],"and":[9,22,39,69,77,83,113,129,152,159,170,194],"exploiting":[10],"their":[11,24],"structural":[12],"benefits":[13],"can":[14,188],"pave":[15],"the":[16,27,61,133,138,161,173],"way":[17],"to":[18,42,59,87,111,168],"formulate":[19],"hydrophobic":[20],"drugs":[21],"potentiate":[23],"activity.":[25],"Herein,":[26],"ability":[28],"of":[29,63,106,137,164,197],"non-ionic":[30],"surfactants":[31],"(labrasol":[32],"\u00ae":[33,76,151],",":[34],"tween":[35,78,107,153],"80,":[36,79],"cremophore":[37],"EL":[38,82],"pluronic":[40,84],"F127)":[41],"form":[43,88,157],"curcumin":[44,96,114,123,140,165,198],"loaded":[45],"with":[47,74],"phosphatidylcholine,":[48],"utilizing":[49],"a":[50],"simple":[51],"method,":[52],"was":[53,57,143],"investigated.":[54],"Molecular":[55],"docking":[56],"used":[58],"understand":[60],"mechanism":[62],"formation.":[65],"The":[66,91,119],"%":[67],"transmittance":[68],"TEM":[70],"exhibited":[71],"formation":[73],"labrasol":[75],"while":[80],"cremophor":[81],"F127":[85],"tended":[86],"mixed":[89,174],"micelles.":[90],"surfactant-based":[92],"nanostructures":[93],"significantly":[94],"improved":[95,122],"dissolution":[97],"(99.2":[98],"\u00b1":[99],"2.6%":[100],"within":[101],"10":[102],"min":[103],"in":[104,116],"case":[105],"80-based":[108],"bicelles)":[109],"compared":[110,167],"liposomes":[112,128,169],"suspension":[115],"non-sink":[117],"conditions.":[118],"prepared":[120],"formulations":[121,176,186],"ex":[124],"vivo":[125],"permeation":[126],"over":[127,145],"suspension.":[131,147],"Further,":[132],"therapeutic":[134],"antiviral":[135,201],"activity":[136],"formulated":[139],"against":[141],"SARS-CoV-2":[142],"potentiated":[144],"Although":[148],"both":[149],"Labrasol":[150],"80":[154],"could":[156],"enhance":[160],"when":[166],"suspension,":[172],"micelles":[175],"depicted":[177],"superiority":[178],"than":[179],"formulations.":[181],"Our":[182],"findings":[183],"provide":[184],"promising":[185],"that":[187],"be":[189],"utilized":[190],"for":[191,203],"further":[192],"preclinical":[193],"clinical":[195],"studies":[196],"therapy":[202],"COVID-19":[204],"patients.":[205]},"counts_by_year":[{"year":2026,"cited_by_count":9},{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":13},{"year":2023,"cited_by_count":14},{"year":2022,"cited_by_count":17}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2021-12-31T00:00:00"}