{"id":"https://openalex.org/W4200501636","doi":"https://doi.org/10.1093/jacamr/dlab185","title":"Replacement of Enterococcus faecalis by Enterococcus faecium as the predominant enterococcus in UK bacteraemias","display_name":"Replacement of Enterococcus faecalis by Enterococcus faecium as the predominant enterococcus in UK bacteraemias","publication_year":2021,"publication_date":"2021-09-30","ids":{"openalex":"https://openalex.org/W4200501636","doi":"https://doi.org/10.1093/jacamr/dlab185","pmid":"https://pubmed.ncbi.nlm.nih.gov/34909690","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8664539"},"language":"en","primary_location":{"id":"doi:10.1093/jacamr/dlab185","doi":"https://doi.org/10.1093/jacamr/dlab185","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jacamr/dlab185","pdf_url":"https://academic.oup.com/jacamr/article-pdf/3/4/dlab185/41717368/dlab185.pdf","source":{"id":"https://openalex.org/S4210190703","display_name":"JAC-Antimicrobial Resistance","issn_l":"2632-1823","issn":["2632-1823"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","oarl","poland-20","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAC-Antimicrobial Resistance","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/jacamr/article-pdf/3/4/dlab185/41717368/dlab185.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041111706","display_name":"Carolyne Horner","orcid":"https://orcid.org/0000-0002-8026-3024","observed_orcids":["https://orcid.org/0000-0002-8026-3024"]},"institutions":[{"id":"https://openalex.org/I2800368655","display_name":"British Society for Antimicrobial Chemotherapy","ror":"https://ror.org/04yw9eb05","country_code":"GB","type":"other","lineage":["https://openalex.org/I2800368655"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Carolyne Horner","raw_affiliation_strings":["British Society for Antimicrobial Chemotherapy, Birmingham, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"British Society for Antimicrobial Chemotherapy, Birmingham, UK","institution_ids":["https://openalex.org/I2800368655"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047369494","display_name":"Shazad Mushtaq","orcid":"https://orcid.org/0000-0002-3908-8332","observed_orcids":["https://orcid.org/0000-0002-3908-8332"]},"institutions":[{"id":"https://openalex.org/I4387153084","display_name":"UK Health Security Agency","ror":"https://ror.org/018h10037","country_code":"GB","type":"government","lineage":["https://openalex.org/I1311074006","https://openalex.org/I4387153084"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Shazad Mushtaq","raw_affiliation_strings":["UK Health Security Agency, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UK Health Security Agency, London, UK","institution_ids":["https://openalex.org/I4387153084"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110830605","display_name":"M Allen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800368655","display_name":"British Society for Antimicrobial Chemotherapy","ror":"https://ror.org/04yw9eb05","country_code":"GB","type":"other","lineage":["https://openalex.org/I2800368655"]},{"id":"https://openalex.org/I4210087189","display_name":"MSD (UK) Limited (United Kingdom)","ror":"https://ror.org/004nn4n27","country_code":"GB","type":"company","lineage":["https://openalex.org/I1285764155","https://openalex.org/I4210087189"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Michael Allen","raw_affiliation_strings":["British Society for Antimicrobial Chemotherapy, Birmingham, UK","Merck Sharp & Dohme (UK) Limited, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"British Society for Antimicrobial Chemotherapy, Birmingham, UK","institution_ids":["https://openalex.org/I2800368655"]},{"raw_affiliation_string":"Merck Sharp & Dohme (UK) Limited, London, UK","institution_ids":["https://openalex.org/I4210087189"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039878003","display_name":"Russell Hope","orcid":"https://orcid.org/0000-0003-2838-6833","observed_orcids":["https://orcid.org/0000-0003-2838-6833"]},"institutions":[{"id":"https://openalex.org/I4387153084","display_name":"UK Health Security Agency","ror":"https://ror.org/018h10037","country_code":"GB","type":"government","lineage":["https://openalex.org/I1311074006","https://openalex.org/I4387153084"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Russell Hope","raw_affiliation_strings":["UK Health Security Agency, London, UK"],"raw_orcid":"https://orcid.org/0000-0003-2838-6833","affiliations":[{"raw_affiliation_string":"UK Health Security Agency, London, UK","institution_ids":["https://openalex.org/I4387153084"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087895940","display_name":"Sarah M. Gerver","orcid":"https://orcid.org/0000-0003-0510-7782","observed_orcids":["https://orcid.org/0000-0003-0510-7782"]},"institutions":[{"id":"https://openalex.org/I4387153084","display_name":"UK Health Security Agency","ror":"https://ror.org/018h10037","country_code":"GB","type":"government","lineage":["https://openalex.org/I1311074006","https://openalex.org/I4387153084"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Sarah Gerver","raw_affiliation_strings":["UK Health Security Agency, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UK Health Security Agency, London, UK","institution_ids":["https://openalex.org/I4387153084"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016916593","display_name":"Christopher M. Longshaw","orcid":"https://orcid.org/0000-0002-5586-7256","observed_orcids":["https://orcid.org/0000-0002-5586-7256"]},"institutions":[{"id":"https://openalex.org/I2800368655","display_name":"British Society for Antimicrobial Chemotherapy","ror":"https://ror.org/04yw9eb05","country_code":"GB","type":"other","lineage":["https://openalex.org/I2800368655"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Christopher Longshaw","raw_affiliation_strings":["British Society for Antimicrobial Chemotherapy, Birmingham, UK","Shionogi B.V., London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"British Society for Antimicrobial Chemotherapy, Birmingham, UK","institution_ids":["https://openalex.org/I2800368655"]},{"raw_affiliation_string":"Shionogi B.V., London, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032359521","display_name":"Rosy Reynolds","orcid":"https://orcid.org/0000-0003-4643-9556","observed_orcids":["https://orcid.org/0000-0003-4643-9556"]},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Rosy Reynolds","raw_affiliation_strings":["Bristol Medical School, University of Bristol, Bristol, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bristol Medical School, University of Bristol, Bristol, UK","institution_ids":["https://openalex.org/I36234482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000013450","display_name":"Neil Woodford","orcid":"https://orcid.org/0000-0003-1396-8953","observed_orcids":["https://orcid.org/0000-0003-1396-8953"]},"institutions":[{"id":"https://openalex.org/I4387153084","display_name":"UK Health Security Agency","ror":"https://ror.org/018h10037","country_code":"GB","type":"government","lineage":["https://openalex.org/I1311074006","https://openalex.org/I4387153084"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Neil Woodford","raw_affiliation_strings":["UK Health Security Agency, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UK Health Security Agency, London, UK","institution_ids":["https://openalex.org/I4387153084"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072423246","display_name":"David M. Livermore","orcid":"https://orcid.org/0000-0002-9856-3703","observed_orcids":["https://orcid.org/0000-0002-9856-3703"]},"institutions":[{"id":"https://openalex.org/I1118541","display_name":"University of East Anglia","ror":"https://ror.org/026k5mg93","country_code":"GB","type":"education","lineage":["https://openalex.org/I1118541"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"David M Livermore","raw_affiliation_strings":["Norwich Medical School, University of East Anglia, Norwich, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Norwich Medical School, University of East Anglia, Norwich, UK","institution_ids":["https://openalex.org/I1118541"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5041111706"],"corresponding_institution_ids":["https://openalex.org/I2800368655"],"apc_list":{"value":1620,"currency":"GBP","value_usd":2430},"apc_paid":{"value":1620,"currency":"GBP","value_usd":2430},"fwci":2.8654,"has_fulltext":true,"cited_by_count":45,"citation_normalized_percentile":{"value":0.92227785,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"3","issue":"4","first_page":"dlab185","last_page":"dlab185"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.9707000255584717,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.9707000255584717,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12167","display_name":"Bacterial Identification and Susceptibility Testing","score":0.009200000204145908,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10897","display_name":"Antibiotic Use and Resistance","score":0.00419999985024333,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/enterococcus-faecium","display_name":"Enterococcus faecium","score":0.9950000047683716},{"id":"https://openalex.org/keywords/enterococcus-faecalis","display_name":"Enterococcus faecalis","score":1.0},{"id":"https://openalex.org/keywords/bloodstream-infection","display_name":"bloodstream infection","score":0.7429999709129333},{"id":"https://openalex.org/keywords/bacteremia","display_name":"bacteremia","score":0.9710000157356262},{"id":"https://openalex.org/keywords/antimicrobial-resistance","display_name":"antimicrobial resistance","score":0.7120000123977661},{"id":"https://openalex.org/keywords/vancomycin-resistance","display_name":"vancomycin resistance","score":0.9430000185966492},{"id":"https://openalex.org/keywords/gentamicin-resistance","display_name":"gentamicin resistance","score":0.9470000267028809},{"id":"https://openalex.org/keywords/ampicillin-resistance","display_name":"ampicillin resistance","score":0.9039999842643738},{"id":"https://openalex.org/keywords/temporal-trends","display_name":"temporal trends","score":0.6269999742507935}],"concepts":[{"id":"https://openalex.org/C2777677444","wikidata":"https://www.wikidata.org/wiki/Q140010","display_name":"Enterococcus faecium","level":3,"score":0.9350532293319702},{"id":"https://openalex.org/C2779895986","wikidata":"https://www.wikidata.org/wiki/Q140014","display_name":"Enterococcus faecalis","level":4,"score":0.7716317772865295},{"id":"https://openalex.org/C2775832221","wikidata":"https://www.wikidata.org/wiki/Q422482","display_name":"Gentamicin","level":3,"score":0.7371466755867004},{"id":"https://openalex.org/C2780585763","wikidata":"https://www.wikidata.org/wiki/Q517258","display_name":"Enterococcus","level":3,"score":0.7337138652801514},{"id":"https://openalex.org/C2778980435","wikidata":"https://www.wikidata.org/wiki/Q424027","display_name":"Vancomycin","level":4,"score":0.5370257496833801},{"id":"https://openalex.org/C2778512257","wikidata":"https://www.wikidata.org/wiki/Q256602","display_name":"Ciprofloxacin","level":3,"score":0.5350633263587952},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.5343325138092041},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5015666484832764},{"id":"https://openalex.org/C2776021129","wikidata":"https://www.wikidata.org/wiki/Q244150","display_name":"Ampicillin","level":3,"score":0.49374136328697205},{"id":"https://openalex.org/C183641309","wikidata":"https://www.wikidata.org/wiki/Q306264","display_name":"Amp resistance","level":4,"score":0.4896686375141144},{"id":"https://openalex.org/C94665300","wikidata":"https://www.wikidata.org/wiki/Q63391344","display_name":"Antibiotic resistance","level":3,"score":0.4675392508506775},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3860175311565399},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.3665720224380493},{"id":"https://openalex.org/C42972112","wikidata":"https://www.wikidata.org/wiki/Q170201","display_name":"Veterinary medicine","level":1,"score":0.3297906517982483},{"id":"https://openalex.org/C2779489039","wikidata":"https://www.wikidata.org/wiki/Q188121","display_name":"Staphylococcus aureus","level":3,"score":0.14259397983551025},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.11426201462745667},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.1093/jacamr/dlab185","doi":"https://doi.org/10.1093/jacamr/dlab185","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jacamr/dlab185","pdf_url":"https://academic.oup.com/jacamr/article-pdf/3/4/dlab185/41717368/dlab185.pdf","source":{"id":"https://openalex.org/S4210190703","display_name":"JAC-Antimicrobial Resistance","issn_l":"2632-1823","issn":["2632-1823"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","oarl","poland-20","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAC-Antimicrobial Resistance","raw_type":"journal-article"},{"id":"pmid:34909690","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34909690","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAC-antimicrobial resistance","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8664539","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8664539/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAC Antimicrob Resist","raw_type":"Text"},{"id":"pmh:oai:research-information.bris.ac.uk:openaire/bd6c57d2-aff4-4ee5-ba9b-397036d1490d","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/1983/bd6c57d2-aff4-4ee5-ba9b-397036d1490d","pdf_url":null,"source":{"id":"https://openalex.org/S7407055359","display_name":"Explore Bristol Research","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Horner, C, Mushtaq, S, Allen, M, Hope, R, Gerver, S, Longshaw, C, Reynolds, R, Woodford, N & Livermore, D M 2021, 'Replacement of Enterococcus faecalis by Enterococcus faecium as the predominant enterococcus in UK bacteraemias', JAC-Antimicrobial Resistance, vol. 3, no. 4, dlab185. https://doi.org/10.1093/jacamr/dlab185","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:research-information.bris.ac.uk:openaire_cris_publications/bd6c57d2-aff4-4ee5-ba9b-397036d1490d","doi":null,"is_oa":true,"landing_page_url":"https://research-information.bris.ac.uk/en/publications/bd6c57d2-aff4-4ee5-ba9b-397036d1490d","pdf_url":null,"source":{"id":"https://openalex.org/S4306400895","display_name":"Bristol Research (University of Bristol)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I36234482","host_organization_name":"University of Bristol","host_organization_lineage":["https://openalex.org/I36234482"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Horner, C, Mushtaq, S, Allen, M, Hope, R, Gerver, S, Longshaw, C, Reynolds, R, Woodford, N & Livermore, D M 2021, 'Replacement of Enterococcus faecalis by Enterococcus faecium as the predominant enterococcus in UK bacteraemias', JAC-Antimicrobial Resistance, vol. 3, no. 4, dlab185. https://doi.org/10.1093/jacamr/dlab185","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:ueaeprints.uea.ac.uk:82816","doi":null,"is_oa":true,"landing_page_url":"https://ueaeprints.uea.ac.uk/id/eprint/82816/1/Published_Version.pdf","pdf_url":"https://ueaeprints.uea.ac.uk/id/eprint/82816/1/Published_Version.pdf","source":{"id":"https://openalex.org/S4306400384","display_name":"UEA Digital Repository (University of East Anglia)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1118541","host_organization_name":"University of East Anglia","host_organization_lineage":["https://openalex.org/I1118541"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1093/jacamr/dlab185","doi":"https://doi.org/10.1093/jacamr/dlab185","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jacamr/dlab185","pdf_url":"https://academic.oup.com/jacamr/article-pdf/3/4/dlab185/41717368/dlab185.pdf","source":{"id":"https://openalex.org/S4210190703","display_name":"JAC-Antimicrobial Resistance","issn_l":"2632-1823","issn":["2632-1823"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","oarl","poland-20","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAC-Antimicrobial Resistance","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320318095","display_name":"National Institute for Health Research Health Protection Research Unit","ror":null},{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320320030","display_name":"British Society for Antimicrobial Chemotherapy","ror":"https://ror.org/04yw9eb05"},{"id":"https://openalex.org/F4320320360","display_name":"University of Bristol","ror":"https://ror.org/0524sp257"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4200501636.pdf","grobid_xml":"https://content.openalex.org/works/W4200501636.grobid-xml"},"referenced_works_count":15,"referenced_works":["https://openalex.org/W1907500624","https://openalex.org/W1961220478","https://openalex.org/W2011920089","https://openalex.org/W2043379193","https://openalex.org/W2122528551","https://openalex.org/W2130071111","https://openalex.org/W2148243249","https://openalex.org/W2151921983","https://openalex.org/W2153787032","https://openalex.org/W2155258425","https://openalex.org/W2406580019","https://openalex.org/W2790895111","https://openalex.org/W2921622580","https://openalex.org/W2940595256","https://openalex.org/W3082681966"],"related_works":["https://openalex.org/W2383322294","https://openalex.org/W2129998124","https://openalex.org/W1975122874","https://openalex.org/W1797126985","https://openalex.org/W4415614962","https://openalex.org/W4415648918","https://openalex.org/W3087407623","https://openalex.org/W2111473598","https://openalex.org/W7223091379","https://openalex.org/W2128831124"],"abstract_inverted_index":{"Abstract":[0],"Objectives":[1],"To":[2],"review":[3],"temporal":[4],"changes":[5],"in":[6,14,57,78,90,103,110,118,147,162,167,185,188,221],"the":[7,38,58,94,104,111,119,148,200],"proportions":[8],"of":[9,54,96,121,150,202,218],"different":[10],"Enterococcus":[11,97,122],"species":[12,237],"recorded":[13],"two":[15,203],"UK":[16,59],"bacteraemia":[17,69],"surveillance":[18,125,154,212],"systems.":[19],"Antibiotic":[20],"resistance":[21,163,176,193],"trends":[22,161],"were":[23],"also":[24],"considered.":[25],"Methods":[26],"We":[27],"reviewed":[28],"data":[29],"for":[30,155],"enterococci":[31,49,86],"from":[32,52,74,100],"2001":[33],"to":[34,46,107,164,177,181,194],"2019":[35],"in:":[36],"(a)":[37],"BSAC":[39,81,153],"Resistance":[40,180],"Surveillance":[41],"Programme,":[42],"which":[43],"collected":[44],"up":[45],"7\u201310":[47],"bloodstream":[48,223],"every":[50],"year":[51,88],"each":[53,87],"23\u201339":[55],"hospitals":[56],"and":[60,62,66,207],"Ireland":[61],"tested":[63],"these":[64],"centrally;":[65],"(b)":[67],"PHE":[68,124],"surveillance,":[70,82],"using":[71],"routine":[72],"results":[73],"NHS":[75],"microbiology":[76],"laboratories":[77],"England.":[79],"Results":[80],"based":[83],"upon":[84],"206\u2013255":[85],"(4486":[89],"total),":[91],"indicated":[92,144,158],"that":[93],"proportion":[95,120,149,217],"faecium":[98,157,220],"rose":[99],"31%":[101],"(212/692)":[102],"period":[105,112],"2001\u20133":[106],"51%":[108],"(354/696)":[109],"2017\u201319,":[113],"balanced":[114],"by":[115],"corresponding":[116],"falls":[117],"faecalis.":[123,241],"provided":[126],"a":[127,145,215],"larger":[128],"dataset,":[129],"with":[130],">5000":[131],"enterococcus":[132],"reports":[133],"per":[134],"year;":[135],"although":[136],"its":[137],"identifications":[138],"are":[139],"less":[140],"precise,":[141],"it":[142],"too":[143],"rise":[146],"E.":[151,156,186,219,240],"faecium.":[152],"no":[159],"consistent":[160],"ampicillin":[165],"(\u226586%":[166],"all":[168,189],"years),":[169],"vancomycin":[170,182],"(annual":[171],"rates":[172],"19%\u201340%)":[173],"or":[174],"high-level":[175,192],"gentamicin":[178,195],"(31%\u201359%).":[179],"remained":[183],"<4%":[184],"faecalis":[187],"years,":[190],"whilst":[191],"fell,":[196],"perhaps":[197],"partly":[198],"reflecting":[199],"decline":[201],"initially":[204],"prevalent":[205],"gentamicin-":[206],"ciprofloxacin-resistant":[208],"clones.":[209],"Conclusions":[210],"Both":[211],"systems":[213],"indicate":[214],"growing":[216],"enterococcal":[222],"infections.":[224],"This":[225],"is":[226],"important":[227],"because":[228],"fewer":[229],"therapeutic":[230],"options":[231],"remain":[232],"against":[233,239],"this":[234],"frequently":[235],"multiresistant":[236],"than":[238]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":15},{"year":2024,"cited_by_count":16},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2021-12-31T00:00:00"}