{"id":"https://openalex.org/W4200470888","doi":"https://doi.org/10.2147/dmso.s326537","title":"Frequency of Diabetic Ketoacidosis and Its Determinants Among Pediatric Diabetes Mellitus Patients in Northwest Ethiopia","display_name":"Frequency of Diabetic Ketoacidosis and Its Determinants Among Pediatric Diabetes Mellitus Patients in Northwest Ethiopia","publication_year":2021,"publication_date":"2021-12-01","ids":{"openalex":"https://openalex.org/W4200470888","doi":"https://doi.org/10.2147/dmso.s326537","pmid":"https://pubmed.ncbi.nlm.nih.gov/34984014","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8699764"},"language":"en","primary_location":{"id":"doi:10.2147/dmso.s326537","doi":"https://doi.org/10.2147/dmso.s326537","is_oa":true,"landing_page_url":"https://doi.org/10.2147/dmso.s326537","pdf_url":"https://www.dovepress.com/getfile.php?fileID=76908","source":{"id":"https://openalex.org/S176615914","display_name":"Diabetes Metabolic Syndrome and Obesity","issn_l":"1178-7007","issn":["1178-7007"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.dovepress.com/getfile.php?fileID=76908","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078088970","display_name":"Atitegeb Abera Kidie","orcid":"https://orcid.org/0000-0002-3010-0438","observed_orcids":["https://orcid.org/0000-0002-3010-0438"]},"institutions":[{"id":"https://openalex.org/I4210159645","display_name":"Woldia University","ror":"https://ror.org/05a7f9k79","country_code":"ET","type":"education","lineage":["https://openalex.org/I4210159645"]}],"countries":["ET"],"is_corresponding":false,"raw_author_name":"Atitegeb Abera Kidie","raw_affiliation_strings":["Department of Public Health, College of Medicine and Health Sciences, Woldia University, Woldia, Ethiopia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Public Health, College of Medicine and Health Sciences, Woldia University, Woldia, Ethiopia","institution_ids":["https://openalex.org/I4210159645"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091537883","display_name":"Ayenew Molla Lakew","orcid":"https://orcid.org/0000-0003-3648-9891","observed_orcids":["https://orcid.org/0000-0003-3648-9891"]},"institutions":[{"id":"https://openalex.org/I8764889","display_name":"University of Gondar","ror":"https://ror.org/0595gz585","country_code":"ET","type":"education","lineage":["https://openalex.org/I8764889"]}],"countries":["ET"],"is_corresponding":true,"raw_author_name":"Ayenew Molla Lakew","raw_affiliation_strings":["Department of Epidemiology and Biostatistics, Institute of Public Health, University of Gondar, Gondar, Ethiopia"],"raw_orcid":"https://orcid.org/0000-0003-3648-9891","affiliations":[{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, Institute of Public Health, University of Gondar, Gondar, Ethiopia","institution_ids":["https://openalex.org/I8764889"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074144973","display_name":"Tiruneh Ayele","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I8764889","display_name":"University of Gondar","ror":"https://ror.org/0595gz585","country_code":"ET","type":"education","lineage":["https://openalex.org/I8764889"]}],"countries":["ET"],"is_corresponding":false,"raw_author_name":"Tiruneh Ayele","raw_affiliation_strings":["Department of Epidemiology and Biostatistics, Institute of Public Health, University of Gondar, Gondar, Ethiopia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, Institute of Public Health, University of Gondar, Gondar, Ethiopia","institution_ids":["https://openalex.org/I8764889"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5091537883"],"corresponding_institution_ids":["https://openalex.org/I8764889"],"apc_list":{"value":2836,"currency":"USD","value_usd":2836},"apc_paid":{"value":2836,"currency":"USD","value_usd":2836},"fwci":1.3697,"has_fulltext":true,"cited_by_count":15,"citation_normalized_percentile":{"value":0.78629361,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":97},"biblio":{"volume":"Volume 14","issue":null,"first_page":"4819","last_page":"4827"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10793","display_name":"Diabetes Management and Education","score":0.0026000000070780516,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11171","display_name":"Diabetes and associated disorders","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/diabetic-ketoacidosis","display_name":"diabetic ketoacidosis","score":1.0},{"id":"https://openalex.org/keywords/pediatric-diabetes","display_name":"pediatric diabetes","score":0.9950000047683716},{"id":"https://openalex.org/keywords/incidence","display_name":"incidence","score":0.652999997138977},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.9819999933242798},{"id":"https://openalex.org/keywords/infection","display_name":"infection","score":0.9509999752044678},{"id":"https://openalex.org/keywords/heart-disease","display_name":"heart disease","score":0.902999997138977},{"id":"https://openalex.org/keywords/treatment-discontinuation","display_name":"treatment discontinuation","score":0.9319999814033508},{"id":"https://openalex.org/keywords/hypokalemia","display_name":"hypokalemia","score":0.8529999852180481},{"id":"https://openalex.org/keywords/insulin-dose","display_name":"insulin dose","score":0.7360000014305115},{"id":"https://openalex.org/keywords/northwest-ethiopia","display_name":"Northwest Ethiopia","score":0.49000000953674316}],"concepts":[{"id":"https://openalex.org/C2781283889","wikidata":"https://www.wikidata.org/wiki/Q1130148","display_name":"Diabetic ketoacidosis","level":3,"score":0.883602499961853},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.7751483917236328},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7038111686706543},{"id":"https://openalex.org/C2775849729","wikidata":"https://www.wikidata.org/wiki/Q1130148","display_name":"Ketoacidosis","level":4,"score":0.625700831413269},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.4201425313949585},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3373945653438568},{"id":"https://openalex.org/C2781232474","wikidata":"https://www.wikidata.org/wiki/Q124407","display_name":"Type 1 diabetes","level":3,"score":0.24095001816749573},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.21296846866607666}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.2147/dmso.s326537","doi":"https://doi.org/10.2147/dmso.s326537","is_oa":true,"landing_page_url":"https://doi.org/10.2147/dmso.s326537","pdf_url":"https://www.dovepress.com/getfile.php?fileID=76908","source":{"id":"https://openalex.org/S176615914","display_name":"Diabetes Metabolic Syndrome and Obesity","issn_l":"1178-7007","issn":["1178-7007"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy","raw_type":"journal-article"},{"id":"pmid:34984014","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34984014","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes, metabolic syndrome and obesity : targets and therapy","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8699764","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8699764/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes Metab Syndr Obes","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:59e21d54710347c3a74ad4ade75bd50e","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/59e21d54710347c3a74ad4ade75bd50e","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Diabetes, Metabolic Syndrome and Obesity, Vol Volume 14, Pp 4819-4827 (2021)","raw_type":"article"},{"id":"pmh:oai:dovepress.com/71621","doi":null,"is_oa":true,"landing_page_url":"https://www.dovepress.com/frequency-of-diabetic-ketoacidosis-and-its-determinants-among-pediatri-peer-reviewed-fulltext-article-DMSO","pdf_url":null,"source":{"id":"https://openalex.org/S4306401012","display_name":"Dove Medical Press (Taylor and Francis Group)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.2147/dmso.s326537","doi":"https://doi.org/10.2147/dmso.s326537","is_oa":true,"landing_page_url":"https://doi.org/10.2147/dmso.s326537","pdf_url":"https://www.dovepress.com/getfile.php?fileID=76908","source":{"id":"https://openalex.org/S176615914","display_name":"Diabetes Metabolic Syndrome and Obesity","issn_l":"1178-7007","issn":["1178-7007"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320324740","display_name":"University of Gondar","ror":"https://ror.org/0595gz585"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4200470888.pdf","grobid_xml":"https://content.openalex.org/works/W4200470888.grobid-xml"},"referenced_works_count":30,"referenced_works":["https://openalex.org/W154397014","https://openalex.org/W1603982962","https://openalex.org/W1913060437","https://openalex.org/W1966590967","https://openalex.org/W1970612621","https://openalex.org/W1979281993","https://openalex.org/W1993911835","https://openalex.org/W2010002759","https://openalex.org/W2012165568","https://openalex.org/W2032913647","https://openalex.org/W2056791334","https://openalex.org/W2057811513","https://openalex.org/W2062621676","https://openalex.org/W2098429606","https://openalex.org/W2109316006","https://openalex.org/W2125593640","https://openalex.org/W2163480179","https://openalex.org/W2257801984","https://openalex.org/W2516944959","https://openalex.org/W2576111043","https://openalex.org/W2582805875","https://openalex.org/W2762837718","https://openalex.org/W2807718461","https://openalex.org/W2908047763","https://openalex.org/W2927529936","https://openalex.org/W2944654230","https://openalex.org/W2944869032","https://openalex.org/W2964035034","https://openalex.org/W2967084704","https://openalex.org/W2996255079"],"related_works":["https://openalex.org/W3040940625","https://openalex.org/W4413309547","https://openalex.org/W4414129041","https://openalex.org/W7214736954","https://openalex.org/W3117965444","https://openalex.org/W3095931208","https://openalex.org/W4414128829","https://openalex.org/W4386316579","https://openalex.org/W7152474842","https://openalex.org/W7140164564"],"abstract_inverted_index":{"BACKGROUND:":[0],"Diabetic":[1],"ketoacidosis":[2],"(DKA)":[3],"is":[4,14],"one":[5],"of":[6,41,55,134,155,164,206,218,239,255],"the":[7,39,53,121,132,249,253],"most":[8],"common":[9],"public":[10,66,87],"health":[11],"problems":[12],"and":[13,29,57,120,215,245],"still":[15],"a":[16,236,241],"major":[17],"child":[18],"killer":[19],"in":[20,32,65,68,89],"sub-Saharan":[21],"African":[22],"countries,":[23],"particularly":[24],"Ethiopia.":[25,70,91],"There":[26],"are":[27],"limited":[28],"inconclusive":[30],"data":[31],"Amhara":[33],"regional":[34],"state;":[35],"moreover,":[36],"predictors":[37],"for":[38,117,131],"incidence":[40,138,162,176],"DKA":[42,56,156,165],"were":[43,248],"not":[44],"investigated":[45],"before.":[46],"Therefore,":[47],"this":[48],"study":[49,76,102],"aimed":[50],"to":[51,82,99,128,147],"assess":[52],"frequency":[54,133,154,254],"its":[58],"determinants":[59,130],"among":[60,168],"pediatric":[61],"diabetes":[62,169],"mellitus":[63,170],"patients":[64,171],"hospitals":[67,88],"northwest":[69,90],"METHODS:":[71],"An":[72,136],"institutional-based":[73],"retrospective":[74],"follow-up":[75],"was":[77,97,106,115,126,145,157,166],"conducted":[78],"from":[79],"September":[80],"2015":[81],"February":[83],"2018":[84],"at":[85,220],"selected":[86],"A":[92],"simple":[93],"random":[94],"sampling":[95],"method":[96],"used":[98,116,146],"select":[100],"389":[101],"subjects.":[103],"Statistical":[104],"analysis":[105],"done":[107],"by":[108],"R-studio":[109],"version":[110],"1.1.4.":[111],"Akakia's":[112],"information":[113],"criteria":[114],"model":[118,125],"comparison":[119],"negative":[122],"binomial":[123],"regression":[124],"fitted":[127],"identify":[129],"DKA.":[135,256],"adjusted":[137],"rate":[139,163,177],"ratio":[140,178],"with":[141,172],"95%":[142,182,191,200,211,225],"confidence":[143],"interval":[144],"declare":[148],"statistical":[149],"significance.":[150],"RESULTS:":[151],"The":[152,161],"average":[153],"1.01":[158],"per":[159],"individual.":[160],"increased":[167],"an":[173,231],"infection":[174],"(adjusted":[175],"(AIRR)":[179],"=":[180,184,189,193,198,202,209,213,223,227],"1.41,":[181],"CI":[183,192,201,212,226],"1.05-2.14),":[185],"heart":[186,233],"diseases":[187],"(AIRR":[188,197,208,222],"4.1,":[190],"1.17-14.68),":[194],"treatment":[195,219,246],"discontinuation":[196,247],"2.91,":[199],"2.02-4.22),":[203],"low":[204,216,237,242],"level":[205],"sodium":[207,243],"1.88,":[210],"1.22-2.89)":[214],"dose":[217,238],"baseline":[221],"0.96,":[224],"0.94-0.97).":[228],"CONCLUSION:":[229],"Having":[230],"infection,":[232],"diseases,":[234],"taking":[235],"treatment,":[240],"level,":[244],"factors":[250],"that":[251],"increase":[252]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":4}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2021-12-31T00:00:00"}