{"id":"https://openalex.org/W4200470245","doi":"https://doi.org/10.1186/s12915-023-01647-6","title":"Dopamine modulates the retinal clock through melanopsin-dependent regulation of cholinergic waves during development","display_name":"Dopamine modulates the retinal clock through melanopsin-dependent regulation of cholinergic waves during development","publication_year":2021,"publication_date":"2021-12-01","ids":{"openalex":"https://openalex.org/W4200470245","doi":"https://doi.org/10.1186/s12915-023-01647-6","pmid":"https://pubmed.ncbi.nlm.nih.gov/37365544","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10294308"},"language":"en","primary_location":{"id":"doi:10.1186/s12915-023-01647-6","doi":"https://doi.org/10.1186/s12915-023-01647-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12915-023-01647-6","pdf_url":"https://bmcbiol.biomedcentral.com/counter/pdf/10.1186/s12915-023-01647-6","source":{"id":"https://openalex.org/S25903957","display_name":"BMC Biology","issn_l":"1741-7007","issn":["1741-7007"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbiol.biomedcentral.com/counter/pdf/10.1186/s12915-023-01647-6","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019341929","display_name":"Chaimaa Kinane","orcid":"https://orcid.org/0009-0009-5089-4579","observed_orcids":["https://orcid.org/0009-0009-5089-4579"]},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Lyon 1 Universit\u00e9","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I119856527","display_name":"Cadi Ayyad University","ror":"https://ror.org/04xf6nm78","country_code":"MA","type":"education","lineage":["https://openalex.org/I119856527"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210129939","display_name":"Institut Cellule Souche et Cerveau","ror":"https://ror.org/03m0zs870","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4210088668","https://openalex.org/I4210129939"]}],"countries":["FR","MA"],"is_corresponding":false,"raw_author_name":"Chaimaa Kinane","raw_affiliation_strings":["Laboratoire de pharmacologie, neurobiologie et comportement, URAC-37, universit\u00e9 Cadi Ayyad, Marrakech, Maroc","Univ Lyon, universit\u00e9 Lyon 1, Inserm, institut cellule souche et cerveau U1208, 69500 Bron, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de pharmacologie, neurobiologie et comportement, URAC-37, universit\u00e9 Cadi Ayyad, Marrakech, Maroc","institution_ids":["https://openalex.org/I119856527"]},{"raw_affiliation_string":"Univ Lyon, universit\u00e9 Lyon 1, Inserm, institut cellule souche et cerveau U1208, 69500 Bron, France","institution_ids":["https://openalex.org/I100532134","https://openalex.org/I154526488","https://openalex.org/I4210129939"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048807489","display_name":"Hugo Calligaro","orcid":"https://orcid.org/0000-0003-0334-6974","observed_orcids":["https://orcid.org/0000-0003-0334-6974"]},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Lyon 1 Universit\u00e9","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I1307098950","display_name":"Salk Institute for Biological Studies","ror":"https://ror.org/03xez1567","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1307098950"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210129939","display_name":"Institut Cellule Souche et Cerveau","ror":"https://ror.org/03m0zs870","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4210088668","https://openalex.org/I4210129939"]}],"countries":["FR","US"],"is_corresponding":false,"raw_author_name":"Hugo Calligaro","raw_affiliation_strings":["Regulatory Biology, Salk Institute for Biological Studies, La Jolla, CA, \u00c9tats-Unis","Univ Lyon, universit\u00e9 Lyon 1, Inserm, institut cellule souche et cerveau U1208, 69500 Bron, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Regulatory Biology, Salk Institute for Biological Studies, La Jolla, CA, \u00c9tats-Unis","institution_ids":["https://openalex.org/I1307098950"]},{"raw_affiliation_string":"Univ Lyon, universit\u00e9 Lyon 1, Inserm, institut cellule souche et cerveau U1208, 69500 Bron, France","institution_ids":["https://openalex.org/I100532134","https://openalex.org/I154526488","https://openalex.org/I4210129939"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039234189","display_name":"Antonin Jandot","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Lyon 1 Universit\u00e9","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210129939","display_name":"Institut Cellule Souche et Cerveau","ror":"https://ror.org/03m0zs870","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4210088668","https://openalex.org/I4210129939"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Antonin Jandot","raw_affiliation_strings":["Univ Lyon, universit\u00e9 Lyon 1, Inserm, institut cellule souche et cerveau U1208, 69500 Bron, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ Lyon, universit\u00e9 Lyon 1, Inserm, institut cellule souche et cerveau U1208, 69500 Bron, France","institution_ids":["https://openalex.org/I100532134","https://openalex.org/I154526488","https://openalex.org/I4210129939"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018718831","display_name":"Christine Coutanson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Lyon 1 Universit\u00e9","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210129939","display_name":"Institut Cellule Souche et Cerveau","ror":"https://ror.org/03m0zs870","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4210088668","https://openalex.org/I4210129939"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Christine Coutanson","raw_affiliation_strings":["Univ Lyon, universit\u00e9 Lyon 1, Inserm, institut cellule souche et cerveau U1208, 69500 Bron, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ Lyon, universit\u00e9 Lyon 1, Inserm, institut cellule souche et cerveau U1208, 69500 Bron, France","institution_ids":["https://openalex.org/I100532134","https://openalex.org/I154526488","https://openalex.org/I4210129939"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054127682","display_name":"Nasser Haddjeri","orcid":"https://orcid.org/0000-0002-2161-2204","observed_orcids":["https://orcid.org/0000-0002-2161-2204"]},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Lyon 1 Universit\u00e9","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210129939","display_name":"Institut Cellule Souche et Cerveau","ror":"https://ror.org/03m0zs870","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4210088668","https://openalex.org/I4210129939"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Nasser Haddjeri","raw_affiliation_strings":["Univ Lyon, universit\u00e9 Lyon 1, Inserm, institut cellule souche et cerveau U1208, 69500 Bron, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ Lyon, universit\u00e9 Lyon 1, Inserm, institut cellule souche et cerveau U1208, 69500 Bron, France","institution_ids":["https://openalex.org/I100532134","https://openalex.org/I154526488","https://openalex.org/I4210129939"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050459536","display_name":"Mohamed Bennis","orcid":"https://orcid.org/0000-0002-8563-9676","observed_orcids":["https://orcid.org/0000-0002-8563-9676"]},"institutions":[{"id":"https://openalex.org/I119856527","display_name":"Cadi Ayyad University","ror":"https://ror.org/04xf6nm78","country_code":"MA","type":"education","lineage":["https://openalex.org/I119856527"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Mohamed Bennis","raw_affiliation_strings":["Laboratoire de pharmacologie, neurobiologie et comportement, URAC-37, universit\u00e9 Cadi Ayyad, Marrakech, Maroc"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de pharmacologie, neurobiologie et comportement, URAC-37, universit\u00e9 Cadi Ayyad, Marrakech, Maroc","institution_ids":["https://openalex.org/I119856527"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5061520379","display_name":"Ouria Dkhissi\u2010Benyahya","orcid":"https://orcid.org/0000-0001-9168-3801","observed_orcids":["https://orcid.org/0000-0001-9168-3801"]},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Lyon 1 Universit\u00e9","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210129939","display_name":"Institut Cellule Souche et Cerveau","ror":"https://ror.org/03m0zs870","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4210088668","https://openalex.org/I4210129939"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Ouria Dkhissi-Benyahya","raw_affiliation_strings":["Univ Lyon, universit\u00e9 Lyon 1, Inserm, institut cellule souche et cerveau U1208, 69500 Bron, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ Lyon, universit\u00e9 Lyon 1, Inserm, institut cellule souche et cerveau U1208, 69500 Bron, France","institution_ids":["https://openalex.org/I100532134","https://openalex.org/I154526488","https://openalex.org/I4210129939"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5061520379"],"corresponding_institution_ids":["https://openalex.org/I100532134","https://openalex.org/I154526488","https://openalex.org/I4210129939"],"apc_list":{"value":3290,"currency":"USD","value_usd":3290},"apc_paid":{"value":3290,"currency":"USD","value_usd":3290},"fwci":0.7437,"has_fulltext":true,"cited_by_count":17,"citation_normalized_percentile":{"value":0.63389752,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"18","issue":"1","first_page":"193","last_page":"193"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10985","display_name":"Sleep and Wakefulness Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dopamine","display_name":"dopamine","score":0.9729999899864197},{"id":"https://openalex.org/keywords/melanopsin","display_name":"melanopsin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/acetylcholine","display_name":"acetylcholine","score":0.8389999866485596},{"id":"https://openalex.org/keywords/retinal-development","display_name":"retinal development","score":0.8730000257492065},{"id":"https://openalex.org/keywords/dopamine-d1-receptor","display_name":"dopamine D1 receptor","score":0.5529999732971191},{"id":"https://openalex.org/keywords/dopamine-d2-receptor","display_name":"dopamine D2 receptor","score":0.9990000128746033},{"id":"https://openalex.org/keywords/light-induced-phase-shift","display_name":"light-induced phase shift","score":0.6859999895095825},{"id":"https://openalex.org/keywords/clock-period","display_name":"clock period","score":0.5360000133514404},{"id":"https://openalex.org/keywords/amacrine-cells","display_name":"amacrine cells","score":0.7820000052452087}],"concepts":[{"id":"https://openalex.org/C15708023","wikidata":"https://www.wikidata.org/wiki/Q80083","display_name":"Humanities","level":1,"score":0.44344601035118103},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3335246443748474},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2407543957233429},{"id":"https://openalex.org/C142362112","wikidata":"https://www.wikidata.org/wiki/Q735","display_name":"Art","level":0,"score":0.20193013548851013}],"mesh":[{"descriptor_ui":"D000099210","descriptor_name":"Melanopsin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002940","descriptor_name":"Circadian Rhythm","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D004298","descriptor_name":"Dopamine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008027","descriptor_name":"Light","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012160","descriptor_name":"Retina","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012165","descriptor_name":"Retinal Ganglion Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D017299","descriptor_name":"Rod Opsins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018678","descriptor_name":"Cholinergic Agents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":9,"locations":[{"id":"doi:10.1186/s12915-023-01647-6","doi":"https://doi.org/10.1186/s12915-023-01647-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12915-023-01647-6","pdf_url":"https://bmcbiol.biomedcentral.com/counter/pdf/10.1186/s12915-023-01647-6","source":{"id":"https://openalex.org/S25903957","display_name":"BMC Biology","issn_l":"1741-7007","issn":["1741-7007"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Biology","raw_type":"journal-article"},{"id":"doi:10.1016/j.msom.2021.10.022","doi":"https://doi.org/10.1016/j.msom.2021.10.022","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.msom.2021.10.022","pdf_url":null,"source":{"id":"https://openalex.org/S4210169930","display_name":"M\u00e9decine du Sommeil","issn_l":"1769-4493","issn":["1769-4493","2352-3395"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["doyens","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"M\u00e9decine du Sommeil","raw_type":"journal-article"},{"id":"doi:10.1101/2021.04.23.441100","doi":"https://doi.org/10.1101/2021.04.23.441100","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2021.04.23.441100","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2021/04/23/2021.04.23.441100.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmh:oai:pubmedcentral.nih.gov:10294308","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10294308","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10294308/pdf/12915_2023_Article_1647.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Biol","raw_type":"Text"},{"id":"pmid:37365544","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37365544","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC biology","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-04923827v1","doi":null,"is_oa":true,"landing_page_url":"https://hal.science/hal-04923827","pdf_url":"https://hal.science/hal-04923827v1/file/Kinane-BMCBiol-2023.pdf","source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Biology, 2023, 21 (146), pp.2473. ⟨10.1186/s12915-023-01647-6⟩","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:HAL:hal-04948614v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.science/hal-04948614","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Biology, 2023, 21 (1), pp.146. ⟨10.1186/s12915-023-01647-6⟩","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:HAL:hal-04952777v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.science/hal-04952777","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"M\u00e9decine du sommeil, 2021, 18 (4), pp.193. ⟨10.1016/j.msom.2021.10.022⟩","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:ea3daefac1804363b643f4409f950355","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/ea3daefac1804363b643f4409f950355","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Biology, Vol 21, Iss 1, Pp 1-15 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12915-023-01647-6","doi":"https://doi.org/10.1186/s12915-023-01647-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12915-023-01647-6","pdf_url":"https://bmcbiol.biomedcentral.com/counter/pdf/10.1186/s12915-023-01647-6","source":{"id":"https://openalex.org/S25903957","display_name":"BMC Biology","issn_l":"1741-7007","issn":["1741-7007"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.46810001134872437,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3699624969","display_name":null,"funder_award_id":"R18147CC","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G5325232492","display_name":null,"funder_award_id":"R20064C","funder_id":"https://openalex.org/F4320326245","funder_display_name":"R\u00e9gion Auvergne-Rh\u00f4ne-Alpes"},{"id":"https://openalex.org/G8090755539","display_name":"How do retinal clocks see light?","funder_award_id":"ANR-18-CE16-0016","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"}],"funders":[{"id":"https://openalex.org/F4320320883","display_name":"Agence Nationale de la Recherche","ror":"https://ror.org/00rbzpz17"},{"id":"https://openalex.org/F4320326245","display_name":"R\u00e9gion Auvergne-Rh\u00f4ne-Alpes","ror":"https://ror.org/00kd6pz94"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4200470245.pdf","grobid_xml":"https://content.openalex.org/works/W4200470245.grobid-xml"},"referenced_works_count":92,"referenced_works":["https://openalex.org/W47463281","https://openalex.org/W1508052510","https://openalex.org/W1604073556","https://openalex.org/W1674901911","https://openalex.org/W1857664998","https://openalex.org/W1958166723","https://openalex.org/W1965644332","https://openalex.org/W1968042048","https://openalex.org/W1971933392","https://openalex.org/W1974899081","https://openalex.org/W1976143125","https://openalex.org/W1976411543","https://openalex.org/W1976499757","https://openalex.org/W1980850878","https://openalex.org/W1986408320","https://openalex.org/W1996550713","https://openalex.org/W1999352727","https://openalex.org/W1999753474","https://openalex.org/W2002761019","https://openalex.org/W2003923732","https://openalex.org/W2011770871","https://openalex.org/W2014313900","https://openalex.org/W2022151784","https://openalex.org/W2028234251","https://openalex.org/W2028837508","https://openalex.org/W2034302165","https://openalex.org/W2034335253","https://openalex.org/W2036992232","https://openalex.org/W2042890889","https://openalex.org/W2043339068","https://openalex.org/W2045308120","https://openalex.org/W2045651752","https://openalex.org/W2047274548","https://openalex.org/W2049690253","https://openalex.org/W2050215536","https://openalex.org/W2054971033","https://openalex.org/W2057663200","https://openalex.org/W2059679976","https://openalex.org/W2061246269","https://openalex.org/W2063344882","https://openalex.org/W2063787806","https://openalex.org/W2064577716","https://openalex.org/W2064637546","https://openalex.org/W2065594360","https://openalex.org/W2072491375","https://openalex.org/W2075860804","https://openalex.org/W2083579647","https://openalex.org/W2087749877","https://openalex.org/W2088406510","https://openalex.org/W2094589586","https://openalex.org/W2096517177","https://openalex.org/W2097744565","https://openalex.org/W2111074197","https://openalex.org/W2116156647","https://openalex.org/W2128878853","https://openalex.org/W2129876877","https://openalex.org/W2136581984","https://openalex.org/W2138995901","https://openalex.org/W2145237902","https://openalex.org/W2145935221","https://openalex.org/W2148067219","https://openalex.org/W2166273532","https://openalex.org/W2171236970","https://openalex.org/W2180165874","https://openalex.org/W2184794175","https://openalex.org/W2460566969","https://openalex.org/W2468014779","https://openalex.org/W2509481375","https://openalex.org/W2568577966","https://openalex.org/W2575509790","https://openalex.org/W2619869976","https://openalex.org/W2622037061","https://openalex.org/W2625594398","https://openalex.org/W2743906461","https://openalex.org/W2766280065","https://openalex.org/W2773057743","https://openalex.org/W2803528885","https://openalex.org/W2808483005","https://openalex.org/W2897376132","https://openalex.org/W2899097517","https://openalex.org/W2899974632","https://openalex.org/W2903181644","https://openalex.org/W2917029100","https://openalex.org/W2918699434","https://openalex.org/W2933733617","https://openalex.org/W2937257532","https://openalex.org/W2989160976","https://openalex.org/W3011797577","https://openalex.org/W3046522212","https://openalex.org/W3048840759","https://openalex.org/W3119567330","https://openalex.org/W4210405171"],"related_works":["https://openalex.org/W7004982052","https://openalex.org/W3159085983","https://openalex.org/W4382056298","https://openalex.org/W7144041036","https://openalex.org/W4392686426","https://openalex.org/W4407801568","https://openalex.org/W561318755","https://openalex.org/W1971933392","https://openalex.org/W7100856353","https://openalex.org/W2047274548"],"abstract_inverted_index":{"Abstract":[0],"Background":[1],"The":[2],"mammalian":[3],"retina":[4,33,119],"contains":[5],"an":[6,231],"autonomous":[7],"circadian":[8,122],"clock":[9,43,94,160,204,221,249],"that":[10,117,132,213],"controls":[11],"various":[12],"aspects":[13],"of":[14,40,76,80,143,158,165,178,201,219,225,234,246],"retinal":[15,42,54,82,93,181,203,227,248],"physiology":[16],"and":[17,37,52,63,87,106,131,171,195,236,242],"function,":[18],"including":[19],"dopamine":[20],"(DA)":[21],"release":[22,186],"by":[23],"amacrine":[24],"cells.":[25],"This":[26],"neurotransmitter":[27],"plays":[28],"a":[29,74],"critical":[30],"role":[31,233],"in":[32,44,60,128,140,149,187,206,238],"development,":[34],"visual":[35],"signalling,":[36],"phase":[38,199],"resetting":[39],"the":[41,61,67,77,81,92,118,133,141,155,159,162,176,188,193,197,202,216,220,239,243,247],"adulthood.":[45],"Interestingly,":[46],"bidirectional":[47],"regulation":[48,224],"between":[49],"dopaminergic":[50,173],"cells":[51,56],"melanopsin-expressing":[53],"ganglion":[55],"has":[57],"been":[58],"demonstrated":[59],"adult":[62,68],"during":[64,96,161,250],"development.":[65,251],"Additionally,":[66],"melanopsin":[69,90,107,237],"knockout":[70,108],"mouse":[71],"(Opn4\u2212/\u2212)":[72],"exhibits":[73],"shortening":[75],"endogenous":[78,156,240],"period":[79,157,194],"clock.":[83],"However,":[84],"whether":[85],"DA":[86,152,185,214,235],"/":[88],"or":[89],"influence":[91],"mechanism":[95],"its":[97],"maturation":[98],"is":[99],"still":[100],"unknown.":[101],"Results":[102],"Using":[103],"wild-type":[104,150,207],"Per2Luc":[105],"(Opn4\u2212/\u2212::Per2Luc)":[109],"mice":[110],"at":[111],"different":[112],"postnatal":[113,125,166],"stages,":[114,191],"we":[115],"found":[116],"generates":[120],"self-sustained":[121],"rhythms":[123,138],"from":[124],"day":[126],"5":[127],"both":[129,169],"genotypes":[130],"ability":[134],"to":[135],"express":[136],"these":[137],"emerges":[139],"absence":[142],"external":[144],"time":[145],"cues.":[146],"Intriguingly,":[147],"only":[148,205],"explants,":[151],"supplementation":[153],"lengthened":[154],"first":[163],"week":[164],"development":[167],"through":[168,222],"D1-":[170],"D2-like":[172],"receptors.":[174],"Furthermore,":[175],"blockade":[177],"spontaneous":[179],"cholinergic":[180],"waves,":[182,228],"which":[183],"drive":[184],"early":[189],"developmental":[190],"shortened":[192],"reduced":[196],"light-induced":[198],"shift":[200],"retinas.":[208],"Conclusions":[209],"These":[210],"data":[211],"suggest":[212],"modulates":[215],"molecular":[217],"core":[218],"melanopsin-dependent":[223],"acetylcholine":[226],"thus":[229],"offering":[230],"unprecedented":[232],"functioning":[241],"light":[244],"response":[245]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":2}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2021-12-31T00:00:00"}