{"id":"https://openalex.org/W4200440474","doi":"https://doi.org/10.53879/id.58.09.11710","title":"SIMULTANEOUS SPECTROPHOTOMETRIC DETERMINATION OF PHENYLEPHRINE HYDROCHLORIDE AND NAPHAZOLINE HYDROCHLORIDE IN EYE DROPS BY CHEMOMETRIC TECHNIQUES AND ARTIFICIAL NEURAL NETWORK","display_name":"SIMULTANEOUS SPECTROPHOTOMETRIC DETERMINATION OF PHENYLEPHRINE HYDROCHLORIDE AND NAPHAZOLINE HYDROCHLORIDE IN EYE DROPS BY CHEMOMETRIC TECHNIQUES AND ARTIFICIAL NEURAL NETWORK","publication_year":2021,"publication_date":"2021-12-04","ids":{"openalex":"https://openalex.org/W4200440474","doi":"https://doi.org/10.53879/id.58.09.11710"},"language":"en","primary_location":{"id":"doi:10.53879/id.58.09.11710","doi":"https://doi.org/10.53879/id.58.09.11710","is_oa":false,"landing_page_url":"https://doi.org/10.53879/id.58.09.11710","pdf_url":null,"source":{"id":"https://openalex.org/S2764981170","display_name":"INDIAN DRUGS","issn_l":"0019-462X","issn":["0019-462X","3048-7161"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4353105718","host_organization_name":"Indian Drug Manufacturers' Association (IDMA)","host_organization_lineage":["https://openalex.org/P4353105718"],"host_organization_lineage_names":["Indian Drug Manufacturers' Association (IDMA)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"INDIAN DRUGS","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058537954","display_name":"Satish A Patel","orcid":"https://orcid.org/0000-0001-7671-4796","observed_orcids":["https://orcid.org/0000-0001-7671-4796"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Satish A. Patel","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5089305030","display_name":"Dharmendrasinh A. Baria","orcid":"https://orcid.org/0000-0003-1101-331X","observed_orcids":["https://orcid.org/0000-0003-1101-331X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dharmendrasinh A. Baria","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"58","issue":"09","first_page":"38","last_page":"46"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10640","display_name":"Spectroscopy and Chemometric Analyses","score":0.9726999998092651,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10640","display_name":"Spectroscopy and Chemometric Analyses","score":0.9726999998092651,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11460","display_name":"Analytical Methods in Pharmaceuticals","score":0.026200000196695328,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11324","display_name":"Spectroscopy Techniques in Biomedical and Chemical Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/phenylephrine-hydrochloride","display_name":"phenylephrine hydrochloride","score":0.9959999918937683},{"id":"https://openalex.org/keywords/naphazoline-hydrochloride","display_name":"naphazoline hydrochloride","score":1.0},{"id":"https://openalex.org/keywords/simultaneous-determination","display_name":"simultaneous determination","score":0.8330000042915344},{"id":"https://openalex.org/keywords/eye-drops","display_name":"eye drops","score":0.8960000276565552},{"id":"https://openalex.org/keywords/multicomponent-analysis","display_name":"multicomponent analysis","score":0.6980000138282776},{"id":"https://openalex.org/keywords/partial-least-squares","display_name":"partial least squares","score":0.8500000238418579},{"id":"https://openalex.org/keywords/principal-component-regression","display_name":"principal component regression","score":1.0},{"id":"https://openalex.org/keywords/neural-network","display_name":"artificial neural networks","score":0.9679999947547913},{"id":"https://openalex.org/keywords/chemometrics","display_name":"chemometrics","score":0.9070000052452087}],"concepts":[{"id":"https://openalex.org/C139945424","wikidata":"https://www.wikidata.org/wiki/Q1940696","display_name":"Mean squared error","level":2,"score":0.7081327438354492},{"id":"https://openalex.org/C2780092901","wikidata":"https://www.wikidata.org/wiki/Q3433612","display_name":"Correlation coefficient","level":2,"score":0.59666907787323},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.5520492196083069},{"id":"https://openalex.org/C74887250","wikidata":"https://www.wikidata.org/wiki/Q3455892","display_name":"Principal component regression","level":3,"score":0.5210563540458679},{"id":"https://openalex.org/C22354355","wikidata":"https://www.wikidata.org/wiki/Q422009","display_name":"Partial least squares regression","level":2,"score":0.5016763210296631},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4705919027328491},{"id":"https://openalex.org/C165838908","wikidata":"https://www.wikidata.org/wiki/Q736777","display_name":"Calibration","level":2,"score":0.44907504320144653},{"id":"https://openalex.org/C151304367","wikidata":"https://www.wikidata.org/wiki/Q910067","display_name":"Chemometrics","level":2,"score":0.44793450832366943},{"id":"https://openalex.org/C161584116","wikidata":"https://www.wikidata.org/wiki/Q1952580","display_name":"Multivariate statistics","level":2,"score":0.4378749132156372},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.41659682989120483},{"id":"https://openalex.org/C27438332","wikidata":"https://www.wikidata.org/wiki/Q2873","display_name":"Principal component analysis","level":2,"score":0.40010392665863037},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.18673884868621826}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.53879/id.58.09.11710","doi":"https://doi.org/10.53879/id.58.09.11710","is_oa":false,"landing_page_url":"https://doi.org/10.53879/id.58.09.11710","pdf_url":null,"source":{"id":"https://openalex.org/S2764981170","display_name":"INDIAN DRUGS","issn_l":"0019-462X","issn":["0019-462X","3048-7161"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4353105718","host_organization_name":"Indian Drug Manufacturers' Association (IDMA)","host_organization_lineage":["https://openalex.org/P4353105718"],"host_organization_lineage_names":["Indian Drug Manufacturers' Association (IDMA)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"INDIAN DRUGS","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.4000000059604645,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W1555220262","https://openalex.org/W1989060081","https://openalex.org/W1990792403","https://openalex.org/W1995808874","https://openalex.org/W2009814300","https://openalex.org/W2024139716","https://openalex.org/W2030891156","https://openalex.org/W2078319723","https://openalex.org/W2080948457","https://openalex.org/W2126112368","https://openalex.org/W2321525600","https://openalex.org/W2513371080","https://openalex.org/W2519547853","https://openalex.org/W2614543745","https://openalex.org/W2767628698","https://openalex.org/W2790245783","https://openalex.org/W3203414957","https://openalex.org/W4235716405"],"related_works":["https://openalex.org/W4409046350","https://openalex.org/W4388594025","https://openalex.org/W3032352560","https://openalex.org/W1966115210","https://openalex.org/W2302540846","https://openalex.org/W7098366579","https://openalex.org/W2098667399","https://openalex.org/W2087001414","https://openalex.org/W1541675525","https://openalex.org/W2031007865"],"abstract_inverted_index":{"Three":[0],"multivariate":[1],"calibration-prediction":[2],"techniques,":[3],"partial":[4],"least":[5],"squares":[6],"(PLS),":[7],"principal":[8],"component":[9],"regression":[10],"(PCR)":[11],"and":[12,31,43,56,99,109,122],"artifi":[13],"cial":[14],"neural":[15],"networks":[16],"(ANN),":[17],"have":[18],"been":[19,47],"applied":[20],"without":[21,138],"separation":[22],"in":[23],"the":[24,51,79,84,123,128],"spectrophotometric":[25],"multi-component":[26],"analysis":[27,137],"of":[28,36,40,53,73,78,86,107],"phenylephrine":[29,41],"hydrochloride":[30,42,45],"naphazoline":[32,44],"hydrochloride.":[33],"A":[34],"set":[35],"25":[37],"synthetic":[38],"mixtures":[39],"has":[46],"evaluated":[48],"to":[49],"determine":[50],"predictability":[52],"PLS,":[54],"PCR":[55],"ANN.":[57],"The":[58,76,112],"absorbance":[59],"data":[60],"matrix":[61],"was":[62,81],"obtained":[63],"by":[64],"measuring":[65],"zero-order":[66],"absorbances":[67],"between":[68,119],"230-300":[69],"nm":[70],"at":[71],"intervals":[72],"3":[74],"nm.":[75],"suitability":[77],"models":[80],"determined":[82],"on":[83],"basis":[85],"root":[87,92,100],"mean":[88,93,101],"square":[89],"error":[90,97,104],"(RMSE),":[91],"squared":[94,102],"cross":[95],"validation":[96,110],"(RMSECV)":[98],"prediction":[103],"(RMSEP)":[105],"values":[106,121],"calibration":[108],"data.":[111],"results":[113],"showed":[114],"a":[115],"very":[116],"good":[117],"correlation":[118],"true":[120],"predicted":[124],"concentration":[125],"values.":[126],"Therefore,":[127],"methods":[129],"developed":[130],"can":[131],"be":[132],"used":[133],"for":[134],"routine":[135],"drug":[136],"chemical":[139],"pre-treatment.":[140]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-07-28T07:46:37.118299","created_date":"2021-12-31T00:00:00"}