{"id":"https://openalex.org/W4200439031","doi":"https://doi.org/10.37219/2528-8253-2021-5-47","title":"The level of peripheral myelin protein and vitamin D in blood serum among patients suffering diabetes mellitus type II and hearing impairment","display_name":"The level of peripheral myelin protein and vitamin D in blood serum among patients suffering diabetes mellitus type II and hearing impairment","publication_year":2021,"publication_date":"2021-11-01","ids":{"openalex":"https://openalex.org/W4200439031","doi":"https://doi.org/10.37219/2528-8253-2021-5-47"},"language":"en","primary_location":{"id":"doi:10.37219/2528-8253-2021-5-47","doi":"https://doi.org/10.37219/2528-8253-2021-5-47","is_oa":true,"landing_page_url":"https://doi.org/10.37219/2528-8253-2021-5-47","pdf_url":"http://www.lorlife.kiev.ua/2021/2021_5_47.pdf","source":{"id":"https://openalex.org/S4210232859","display_name":"OTORHINOLARYNGOLOGY","issn_l":"2528-8245","issn":["2528-8245","2528-8253"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"OTORHINOLARYNGOLOGY","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.lorlife.kiev.ua/2021/2021_5_47.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113977019","display_name":"Tetiana A. Shidlovskaya","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210114153","display_name":"State Institution \u201cO. S. Kolomiychenko Institute of Otolaryngology of National Academy of Medical Sciences of Ukraine\u201d","ror":"https://ror.org/026fxjf64","country_code":"UA","type":"facility","lineage":["https://openalex.org/I4210114153","https://openalex.org/I4210144782"]}],"countries":["UA"],"is_corresponding":false,"raw_author_name":"Tetiana A. Shidlovskaya","raw_affiliation_strings":["State Institution \u201cO.S. Kolomiychenko Institute of Otolaryngology of National Academy of Medical Science of Ukraine\u201d; Kyiv, Ukraine"],"raw_orcid":"https://orcid.org/0000-0002-7894-359X","affiliations":[{"raw_affiliation_string":"State Institution \u201cO.S. Kolomiychenko Institute of Otolaryngology of National Academy of Medical Science of Ukraine\u201d; Kyiv, Ukraine","institution_ids":["https://openalex.org/I4210114153"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034332963","display_name":"Tamara V. Shidlovskaya","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210114153","display_name":"State Institution \u201cO. S. Kolomiychenko Institute of Otolaryngology of National Academy of Medical Sciences of Ukraine\u201d","ror":"https://ror.org/026fxjf64","country_code":"UA","type":"facility","lineage":["https://openalex.org/I4210114153","https://openalex.org/I4210144782"]}],"countries":["UA"],"is_corresponding":false,"raw_author_name":"Tamara V. Shidlovskaya","raw_affiliation_strings":["State Institution \u201cO.S. Kolomiychenko Institute of Otolaryngology of National Academy of Medical Science of Ukraine\u201d; Kyiv, Ukraine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Institution \u201cO.S. Kolomiychenko Institute of Otolaryngology of National Academy of Medical Science of Ukraine\u201d; Kyiv, Ukraine","institution_ids":["https://openalex.org/I4210114153"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033185450","display_name":"Nadiya Ya. Navalkivska","orcid":"https://orcid.org/0000-0001-7191-8618","observed_orcids":["https://orcid.org/0000-0001-7191-8618"]},"institutions":[{"id":"https://openalex.org/I4210114153","display_name":"State Institution \u201cO. S. Kolomiychenko Institute of Otolaryngology of National Academy of Medical Sciences of Ukraine\u201d","ror":"https://ror.org/026fxjf64","country_code":"UA","type":"facility","lineage":["https://openalex.org/I4210114153","https://openalex.org/I4210144782"]}],"countries":["UA"],"is_corresponding":false,"raw_author_name":"Nadiya Ya. Navalkivska","raw_affiliation_strings":["State Institution \u201cO.S. Kolomiychenko Institute of Otolaryngology of National Academy of Medical Science of Ukraine\u201d; Kyiv, Ukraine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Institution \u201cO.S. Kolomiychenko Institute of Otolaryngology of National Academy of Medical Science of Ukraine\u201d; Kyiv, Ukraine","institution_ids":["https://openalex.org/I4210114153"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210114153"],"apc_list":null,"apc_paid":null,"fwci":0.1353,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.33623804,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":null,"issue":"No5(4) 2021","first_page":"47","last_page":"54"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10334","display_name":"Hearing, Cochlea, Tinnitus, Genetics","score":0.9463000297546387,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10334","display_name":"Hearing, Cochlea, Tinnitus, Genetics","score":0.9463000297546387,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10283","display_name":"Hearing Loss and Rehabilitation","score":0.033399999141693115,"subfield":{"id":"https://openalex.org/subfields/3616","display_name":"Speech and Hearing"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10542","display_name":"Vestibular and auditory disorders","score":0.009600000455975533,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vitamin-d","display_name":"vitamin D","score":0.9819999933242798},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.972000002861023},{"id":"https://openalex.org/keywords/sensorineural-hearing-loss","display_name":"sensorineural hearing loss","score":0.9909999966621399},{"id":"https://openalex.org/keywords/diabetes-complications","display_name":"diabetes complications","score":0.6349999904632568},{"id":"https://openalex.org/keywords/demyelination","display_name":"demyelination","score":0.9229999780654907},{"id":"https://openalex.org/keywords/serum-biomarkers","display_name":"serum biomarkers","score":0.8240000009536743},{"id":"https://openalex.org/keywords/vitamin-d-deficiency","display_name":"vitamin D deficiency","score":0.6079999804496765},{"id":"https://openalex.org/keywords/blood-glucose-fluctuation","display_name":"blood glucose fluctuation","score":0.5550000071525574},{"id":"https://openalex.org/keywords/auditory-nerve-damage","display_name":"auditory nerve damage","score":0.48899999260902405},{"id":"https://openalex.org/keywords/diabetic-neuropathy","display_name":"diabetic neuropathy","score":0.38999998569488525},{"id":"https://openalex.org/keywords/vitamin-b12-supplementation","display_name":"vitamin B12 supplementation","score":0.38600000739097595},{"id":"https://openalex.org/keywords/vitamin-e-supplementation","display_name":"vitamin E supplementation","score":0.3199999928474426}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8887765407562256},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.7888995409011841},{"id":"https://openalex.org/C2910068830","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 Diabetes Mellitus","level":3,"score":0.6558116674423218},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6313492655754089},{"id":"https://openalex.org/C2780485761","wikidata":"https://www.wikidata.org/wiki/Q275157","display_name":"Blood sugar","level":3,"score":0.5646056532859802},{"id":"https://openalex.org/C2780607864","wikidata":"https://www.wikidata.org/wiki/Q928697","display_name":"Sensorineural hearing loss","level":3,"score":0.5399063229560852},{"id":"https://openalex.org/C145333580","wikidata":"https://www.wikidata.org/wiki/Q260946","display_name":"Anamnesis","level":2,"score":0.5102443695068359},{"id":"https://openalex.org/C2780493683","wikidata":"https://www.wikidata.org/wiki/Q16035842","display_name":"Hearing loss","level":2,"score":0.4396517276763916},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.43166959285736084},{"id":"https://openalex.org/C2781383708","wikidata":"https://www.wikidata.org/wiki/Q7261165","display_name":"Pure tone audiometry","level":4,"score":0.42767682671546936},{"id":"https://openalex.org/C2780554537","wikidata":"https://www.wikidata.org/wiki/Q758881","display_name":"Audiometry","level":3,"score":0.28716129064559937},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.25960928201675415},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.17015165090560913}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.37219/2528-8253-2021-5-47","doi":"https://doi.org/10.37219/2528-8253-2021-5-47","is_oa":true,"landing_page_url":"https://doi.org/10.37219/2528-8253-2021-5-47","pdf_url":"http://www.lorlife.kiev.ua/2021/2021_5_47.pdf","source":{"id":"https://openalex.org/S4210232859","display_name":"OTORHINOLARYNGOLOGY","issn_l":"2528-8245","issn":["2528-8245","2528-8253"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"OTORHINOLARYNGOLOGY","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.37219/2528-8253-2021-5-47","doi":"https://doi.org/10.37219/2528-8253-2021-5-47","is_oa":true,"landing_page_url":"https://doi.org/10.37219/2528-8253-2021-5-47","pdf_url":"http://www.lorlife.kiev.ua/2021/2021_5_47.pdf","source":{"id":"https://openalex.org/S4210232859","display_name":"OTORHINOLARYNGOLOGY","issn_l":"2528-8245","issn":["2528-8245","2528-8253"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"OTORHINOLARYNGOLOGY","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4200439031.pdf","grobid_xml":"https://content.openalex.org/works/W4200439031.grobid-xml"},"referenced_works_count":7,"referenced_works":["https://openalex.org/W2084791795","https://openalex.org/W2508241090","https://openalex.org/W2561727131","https://openalex.org/W2774743973","https://openalex.org/W2948974588","https://openalex.org/W2979859772","https://openalex.org/W2988719937"],"related_works":["https://openalex.org/W4411668184","https://openalex.org/W4402713656","https://openalex.org/W4389239513","https://openalex.org/W3026172063","https://openalex.org/W7217673587","https://openalex.org/W4383684824","https://openalex.org/W2247015049","https://openalex.org/W3030107712","https://openalex.org/W3036808801","https://openalex.org/W2752305079"],"abstract_inverted_index":{"Topicality:":[0],"While":[1,416],"diabetes":[2,53,68,109,160,192,216,269,302,334,358,384,500,554,618,657,678,702,750,787,791,864],"mellitus":[3,54,69,110,161,217,270,303,385,501,619,658,679,703,751,792,865],"is":[4,253,711,755,816],"often":[5,457,489,525],"observed":[6,319,508],"hearing":[7,11,58,708,744,797,859],"impairment,":[8],"including":[9],"sensorineural":[10,707,743,796,858],"loss":[12,709,745],"(SNHL).":[13],"On":[14],"the":[15,22,33,40,80,85,119,148,151,174,180,183,194,197,202,220,259,273,286,297,308,343,355,369,380,417,420,460,478,481,495,530,557,615,626,629,637,641,648,661,666,670,683,691,695,716,731,747,767,769,782,855],"other":[16],"hand,":[17],"metabolic":[18,401],"changes,":[19],"disorders":[20,644,686],"of":[21,26,35,42,79,108,139,150,173,176,196,199,222,232,242,249,264,275,278,289,299,310,323,350,357,371,383,391,395,400,414,419,422,426,438,465,470,483,497,512,516,545,559,571,577,584,610,617,631,656,663,673,677,685,694,718,733,737,749,762,771,784,786,806,810,824,828,837,847,857],"hemostasis":[23],"system,":[24],"lack":[25,464,558,775],"vitamins":[27],"and":[28,47,61,111,144,162,166,182,406,410,429,468,532,555,565,589,633,706,735,776,826,850],"minerals":[29],"can":[30],"lead":[31],"to":[32,38,74,84,227,244,538],"development":[34,298,413,684,856],"SNHL.":[36,327],"Aim:":[37],"examine":[39],"level":[41,175,198,221,241,317,370,428,482],"peripheral":[43],"myelin":[44],"protein":[45],"(PMP)":[46],"vitamin":[48,311,372,397,430,466,504,517,560,578,634,763,829,851],"D":[49,373,505,518,561,579,635,764,830,852],"in":[50,114,118,157,187,201,210,235,258,266,285,296,301,315,320,329,347,365,374,386,398,436,443,450,459,473,480,491,510,519,548,551,563,569,582,586,590,592,596,606,628,636,647,665,690,715,720,725,813,832,854],"patients":[51,66,90,98,105,128,158,214,267,325,330,351,387,423,439,552,585,611,700,741,833,862],"with":[52,57,67,106,129,159,179,215,268,326,331,352,388,424,440,446,529,541,553,612,701,742,766,790,795,834,863],"type":[55,70,304,620,659,680,704,752,793,866],"II":[56,621,681,705,753,794],"impairment.":[59],"Materials":[60],"methods:":[62],"Were":[63],"examined":[64,126,324],"43":[65],"II,":[71,660],"who,":[72],"according":[73,83],"subjective":[75],"audiometry,":[76],"revealed":[77],"SNHL":[78,163,300,332,353,389,498,613],"I-II":[81],"degree":[82],"International":[86],"Classification.":[87],"We":[88],"divided":[89],"into":[91],"two":[92],"groups:":[93],"group":[94,101,124,137,188,211,218,236,366,444,462,474,492,496,520,539,549,587,593,597],"1st":[95,165,219],"included":[96],"22":[97],"without":[99,131,333,499],"complications,":[100],"2nd":[102,189,445,475,521,550,588],"\u2013":[103,408,568,599],"21":[104],"complications":[107,785],"sudden":[112],"changes":[113,809],"blood":[115,133,203,375,451,638,721],"sugar":[116,811],"levels":[117,263,580,761,812,823],"anamnesis.":[120,667],"As":[121,306],"a":[122,170,240,392,447,463,542,575,653,674,712,756,801,807,817],"comparison":[123,184,461,533],"were":[125,318,485,645],"15":[127,140],"SNP":[130],"high":[132],"sugar.":[134],"The":[135,839],"control":[136,181,260,344,531],"consisted":[138],"healthy":[141],"individuals.":[142],"Results":[143],"discussion:":[145],"When":[146],"analyzing":[147],"results":[149],"study,":[152],"it":[153,432],"was":[154,169,205,224,338,362,433,454,507],"found":[155,434,646],"that":[156,435,605],"(groups":[164],"2nd)":[167],"there":[168,453,622,710,754,815],"significant":[171,208,713,757,818],"increase":[172,195,714],"PMP":[177,200,223,238,265,427,484,632,719,825],"comparing":[178,528],"group.":[185,261],"Moreover,":[186,472,640],"(with":[190],"complicated":[191,287,381,448,654,675,726,802],"mellitus)":[193],"serum":[204,452],"reliably":[206],"more":[207,256,283,377,411,456,488,524,723,820],"than":[209,257,458,490,831],"1st.":[212,493],"In":[213,494,573,699,740],"from":[225,342,477,625],"2.3":[226],"9.8":[228],"ng/ml":[229,246],"(average":[230,247],"value":[231,248],"7.2\u00b10.5":[233],"ng/ml),":[234],"2":[237],"had":[239,652],"8.5":[243],"37.2":[245],"24.3\u00b11.7":[250],"ng/ml).":[251],"This":[252,668],"significantly":[254,341,455,487,523],"(P<0.01)":[255],"Elevated":[262],"may":[271,729,842],"indicate":[272,730,843],"processes":[274,732,849],"demyelination,":[276],"damage":[277,736],"neural":[279,692,738],"structures,":[280],"which":[281,728],"are":[282,623],"pronounced":[284,643,724,821],"course":[288,382,544,655,676,836],"diabetes,":[290,441,727],"which,":[291],"obviously,":[292],"have":[293,603,800],"some":[294],"significance":[295],"II.":[305],"for":[307],"content":[309,630,717],"D,":[312,431],"certain":[313,393],"reductions":[314],"its":[316,566,774],"all":[321,607],"groups":[322,349,437,609],"However,":[328],"mellitus,":[335,359],"this":[336,360,396],"decrease":[337,576],"not":[339,526],"differing":[340],"values.":[345],"But":[346],"both":[348],"on":[354,614,682,746,781],"background":[356,616,748,783],"difference":[361],"significant,":[363],"especially":[364,442,779],"2nd.":[367],"Decreasing":[368],"serum,":[376,722],"expressed":[378,412],"at":[379,403],"testifies":[390],"role":[394,672,846],"deepening":[399],"disturbances":[402],"such":[404],"patients,":[405],"consequently":[407],"faster":[409],"complications.":[415],"analysis":[418],"distribution":[421],"deviation":[425],"course,":[449,803],"B":[467],"increasing":[469,822],"PMP.":[471],"deviations":[476,624],"norm":[479,627],"also":[486,536,651],"(group":[502],"3rd)":[503],"deficiency":[506,515,567,853],"only":[509,527],"13.3%":[511],"cases.":[513,572],"A":[514],"occurred":[522,562,581,780],"group,":[534],"but":[535],"relatively":[537],"1st,":[540,594],"milder":[543,835],"diabetes.":[546],"Thus,":[547,601],"SNHL,":[556],"26.6%":[564],"73.3%":[570],"general,":[574],"100%":[583],"80%":[591],"while":[595],"3rd":[598],"30%.":[600],"researches":[602],"shown":[604],"studied":[608],"serum.":[639],"most":[642],"examined,":[649],"who":[650,799],"episodes":[662,805],"hypoglycemia":[664],"indicates":[669,773],"possible":[671],"(including":[687],"demyelinating":[688,848],"processes)":[689],"structures":[693],"auditory":[696],"analyzer.":[697],"Conclusions:":[698],"demyelination":[734],"structures.":[739],"(P":[758],"<0.01)":[759],"reduced":[760],"compared":[765],"control,":[768],"severity":[770],"reducing":[772],"even":[777],"deficiency,":[778],"mellitus.":[788],"Patients":[789],"loss,":[798],"polyneuropathy,":[804],"severe":[808],"anamnesis,":[814],"(P<0.05)":[819],"decreasing":[827],"disease.":[838],"obtained":[840],"data":[841],"an":[844],"important":[845],"impairment":[860],"among":[861],"2.":[867]},"counts_by_year":[{"year":2024,"cited_by_count":1}],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2021-12-31T00:00:00"}