{"id":"https://openalex.org/W4200412138","doi":"https://doi.org/10.1097/wno.0000000000001374","title":"Is Neuroretinitis Associated With Multiple Sclerosis?","display_name":"Is Neuroretinitis Associated With Multiple Sclerosis?","publication_year":2021,"publication_date":"2021-10-22","ids":{"openalex":"https://openalex.org/W4200412138","doi":"https://doi.org/10.1097/wno.0000000000001374","pmid":"https://pubmed.ncbi.nlm.nih.gov/34873139"},"language":"en","primary_location":{"id":"doi:10.1097/wno.0000000000001374","doi":"https://doi.org/10.1097/wno.0000000000001374","is_oa":false,"landing_page_url":"https://doi.org/10.1097/wno.0000000000001374","pdf_url":null,"source":{"id":"https://openalex.org/S195816289","display_name":"Journal of Neuro-Ophthalmology","issn_l":"1070-8022","issn":["1070-8022","1536-5166"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neuro-Ophthalmology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111144098","display_name":"Neil R. Miller","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1295876152","display_name":"Houston Methodist","ror":"https://ror.org/027zt9171","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295876152"]},{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]},{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]},{"id":"https://openalex.org/I2800446032","display_name":"Rhode Island Hospital","ror":"https://ror.org/01aw9fv09","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800446032","https://openalex.org/I4210151747"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Neil R. Miller","raw_affiliation_strings":["Wilmer Eye Institute (NRM), Johns Hopkins University School of Medicine, Baltimore, Maryland; Neuro-Ophthalmology Unit (LNJ, TB), Warren Alpert Medical School of Brown University, Lifespan, Rhode Island Hospital, Providence, Rhode Island; Department of Ophthalmology and Visual Sciences (GPVS), Washington University in St. Louis School of Medicine, St. Louis, Missouri; and Chair, Blanton Eye Institute (AGL), Houston Methodist Hospital, Houston, Texas","Maryland","Missouri","Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wilmer Eye Institute (NRM), Johns Hopkins University School of Medicine, Baltimore, Maryland; Neuro-Ophthalmology Unit (LNJ, TB), Warren Alpert Medical School of Brown University, Lifespan, Rhode Island Hospital, Providence, Rhode Island; Department of Ophthalmology and Visual Sciences (GPVS), Washington University in St. Louis School of Medicine, St. Louis, Missouri; and Chair, Blanton Eye Institute (AGL), Houston Methodist Hospital, Houston, Texas","institution_ids":["https://openalex.org/I1295876152","https://openalex.org/I145311948","https://openalex.org/I204465549","https://openalex.org/I27804330","https://openalex.org/I2799853436","https://openalex.org/I2800446032"]},{"raw_affiliation_string":"Maryland","institution_ids":[]},{"raw_affiliation_string":"Missouri","institution_ids":[]},{"raw_affiliation_string":"Texas","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103292830","display_name":"Lenworth N. Johnson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1295876152","display_name":"Houston Methodist","ror":"https://ror.org/027zt9171","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295876152"]},{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lenworth N. Johnson","raw_affiliation_strings":["Department of Ophthalmology and Visual Sciences (GPVS), Washington University in St. Louis School of Medicine, St. Louis, Missouri","Wilmer Eye Institute (NRM), Johns Hopkins University School of Medicine, Baltimore, Maryland","and Chair, Blanton Eye Institute (AGL), Houston Methodist Hospital, Houston, Texas","Maryland","Missouri","Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology and Visual Sciences (GPVS), Washington University in St. Louis School of Medicine, St. Louis, Missouri","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Wilmer Eye Institute (NRM), Johns Hopkins University School of Medicine, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]},{"raw_affiliation_string":"and Chair, Blanton Eye Institute (AGL), Houston Methodist Hospital, Houston, Texas","institution_ids":["https://openalex.org/I1295876152"]},{"raw_affiliation_string":"Maryland","institution_ids":[]},{"raw_affiliation_string":"Missouri","institution_ids":[]},{"raw_affiliation_string":"Texas","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027988844","display_name":"Tatiana V. Bakaeva","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1295876152","display_name":"Houston Methodist","ror":"https://ror.org/027zt9171","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295876152"]},{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tatiana Bakaeva","raw_affiliation_strings":["Department of Ophthalmology and Visual Sciences (GPVS), Washington University in St. Louis School of Medicine, St. Louis, Missouri","Wilmer Eye Institute (NRM), Johns Hopkins University School of Medicine, Baltimore, Maryland","and Chair, Blanton Eye Institute (AGL), Houston Methodist Hospital, Houston, Texas","Maryland","Missouri","Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology and Visual Sciences (GPVS), Washington University in St. Louis School of Medicine, St. Louis, Missouri","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Wilmer Eye Institute (NRM), Johns Hopkins University School of Medicine, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]},{"raw_affiliation_string":"and Chair, Blanton Eye Institute (AGL), Houston Methodist Hospital, Houston, Texas","institution_ids":["https://openalex.org/I1295876152"]},{"raw_affiliation_string":"Maryland","institution_ids":[]},{"raw_affiliation_string":"Missouri","institution_ids":[]},{"raw_affiliation_string":"Texas","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034757525","display_name":"Gregory P. Van Stavern","orcid":"https://orcid.org/0000-0003-0289-9956","observed_orcids":["https://orcid.org/0000-0003-0289-9956"]},"institutions":[{"id":"https://openalex.org/I1295876152","display_name":"Houston Methodist","ror":"https://ror.org/027zt9171","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295876152"]},{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Gregory P. Van Stavern","raw_affiliation_strings":["Department of Ophthalmology and Visual Sciences (GPVS), Washington University in St. Louis School of Medicine, St. Louis, Missouri","Wilmer Eye Institute (NRM), Johns Hopkins University School of Medicine, Baltimore, Maryland","and Chair, Blanton Eye Institute (AGL), Houston Methodist Hospital, Houston, Texas","Maryland","Missouri","Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology and Visual Sciences (GPVS), Washington University in St. Louis School of Medicine, St. Louis, Missouri","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Wilmer Eye Institute (NRM), Johns Hopkins University School of Medicine, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]},{"raw_affiliation_string":"and Chair, Blanton Eye Institute (AGL), Houston Methodist Hospital, Houston, Texas","institution_ids":["https://openalex.org/I1295876152"]},{"raw_affiliation_string":"Maryland","institution_ids":[]},{"raw_affiliation_string":"Missouri","institution_ids":[]},{"raw_affiliation_string":"Texas","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081144092","display_name":"Andrew G. Lee","orcid":"https://orcid.org/0000-0002-2473-299X","observed_orcids":["https://orcid.org/0000-0002-2473-299X","https://orcid.org/0000-0002-5899-2239"]},"institutions":[{"id":"https://openalex.org/I1295876152","display_name":"Houston Methodist","ror":"https://ror.org/027zt9171","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295876152"]},{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew G. Lee","raw_affiliation_strings":["Department of Ophthalmology and Visual Sciences (GPVS), Washington University in St. Louis School of Medicine, St. Louis, Missouri","Wilmer Eye Institute (NRM), Johns Hopkins University School of Medicine, Baltimore, Maryland","and Chair, Blanton Eye Institute (AGL), Houston Methodist Hospital, Houston, Texas","Maryland","Missouri","Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology and Visual Sciences (GPVS), Washington University in St. Louis School of Medicine, St. Louis, Missouri","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Wilmer Eye Institute (NRM), Johns Hopkins University School of Medicine, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]},{"raw_affiliation_string":"and Chair, Blanton Eye Institute (AGL), Houston Methodist Hospital, Houston, Texas","institution_ids":["https://openalex.org/I1295876152"]},{"raw_affiliation_string":"Maryland","institution_ids":[]},{"raw_affiliation_string":"Missouri","institution_ids":[]},{"raw_affiliation_string":"Texas","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5034757525"],"corresponding_institution_ids":["https://openalex.org/I1295876152","https://openalex.org/I145311948","https://openalex.org/I204465549","https://openalex.org/I2799853436"],"apc_list":null,"apc_paid":null,"fwci":0.333,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.58107028,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":"42","issue":"1","first_page":"126","last_page":"130"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10137","display_name":"Multiple Sclerosis Research Studies","score":0.9253000020980835,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10137","display_name":"Multiple Sclerosis Research Studies","score":0.9253000020980835,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12599","display_name":"Retinal and Optic Conditions","score":0.03620000183582306,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11194","display_name":"Ocular Diseases and Beh\u00e7et\u2019s Syndrome","score":0.02070000022649765,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuroretinitis","display_name":"neuroretinitis","score":0.9980000257492065},{"id":"https://openalex.org/keywords/multiple-sclerosis","display_name":"multiple sclerosis","score":0.9980000257492065},{"id":"https://openalex.org/keywords/demyelinating-optic-neuritis","display_name":"demyelinating optic neuritis","score":0.8899999856948853},{"id":"https://openalex.org/keywords/retinal-periphlebitis","display_name":"retinal periphlebitis","score":0.7799999713897705},{"id":"https://openalex.org/keywords/optic-nerve-swelling","display_name":"optic nerve swelling","score":0.3370000123977661},{"id":"https://openalex.org/keywords/intraocular-inflammation","display_name":"intraocular inflammation","score":0.5569999814033508},{"id":"https://openalex.org/keywords/covid-19","display_name":"COVID-19 pandemic","score":0.6169999837875366},{"id":"https://openalex.org/keywords/differential-diagnosis","display_name":"differential diagnosis","score":0.6209999918937683},{"id":"https://openalex.org/keywords/vision-loss","display_name":"vision loss","score":0.4350000023841858},{"id":"https://openalex.org/keywords/neuro-ophthalmology","display_name":"neuro-ophthalmology","score":0.578000009059906},{"id":"https://openalex.org/keywords/demyelination","display_name":"demyelination","score":0.45899999141693115},{"id":"https://openalex.org/keywords/intermediate-uveitis","display_name":"intermediate uveitis","score":0.4830000102519989}],"concepts":[{"id":"https://openalex.org/C2780640218","wikidata":"https://www.wikidata.org/wiki/Q8277","display_name":"Multiple sclerosis","level":2,"score":0.8585061430931091},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5541695952415466},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.42892590165138245},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.10796564817428589}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009103","descriptor_name":"Multiple Sclerosis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D009103","descriptor_name":"Multiple Sclerosis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D009902","descriptor_name":"Optic Neuritis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D012173","descriptor_name":"Retinitis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D012173","descriptor_name":"Retinitis","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1097/wno.0000000000001374","doi":"https://doi.org/10.1097/wno.0000000000001374","is_oa":false,"landing_page_url":"https://doi.org/10.1097/wno.0000000000001374","pdf_url":null,"source":{"id":"https://openalex.org/S195816289","display_name":"Journal of Neuro-Ophthalmology","issn_l":"1070-8022","issn":["1070-8022","1536-5166"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neuro-Ophthalmology","raw_type":"journal-article"},{"id":"pmid:34873139","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34873139","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9763000011444092}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W16185606","https://openalex.org/W50982117","https://openalex.org/W1525161423","https://openalex.org/W1576830483","https://openalex.org/W1971439222","https://openalex.org/W1975555493","https://openalex.org/W1982736163","https://openalex.org/W1996196701","https://openalex.org/W2002693811","https://openalex.org/W2004724821","https://openalex.org/W2031973605","https://openalex.org/W2042368438","https://openalex.org/W2043407877","https://openalex.org/W2047617746","https://openalex.org/W2064850754","https://openalex.org/W2080803040","https://openalex.org/W2081839911","https://openalex.org/W2101119534","https://openalex.org/W2101680752","https://openalex.org/W2117544593","https://openalex.org/W2141936327","https://openalex.org/W2318807759","https://openalex.org/W2331632017","https://openalex.org/W2411506340","https://openalex.org/W2428784370","https://openalex.org/W2593349093","https://openalex.org/W2789846041","https://openalex.org/W2889321438","https://openalex.org/W2897074525","https://openalex.org/W2911658427","https://openalex.org/W2954609420","https://openalex.org/W3141181971","https://openalex.org/W4206145025","https://openalex.org/W4234850775","https://openalex.org/W4238064437","https://openalex.org/W4298126364","https://openalex.org/W6842894363"],"related_works":["https://openalex.org/W2064850754","https://openalex.org/W4394618220","https://openalex.org/W7214710791","https://openalex.org/W2470330655","https://openalex.org/W4391252420","https://openalex.org/W1811107069","https://openalex.org/W2746298931","https://openalex.org/W4390667975","https://openalex.org/W2420135169","https://openalex.org/W2436814352"],"abstract_inverted_index":{"G.":[0,7,3252,3255],"P.":[1,3256],"Van":[2,3257],"Stavern,":[3],"MD":[4,9,1417],"and":[5,19,64,100,141,164,196,231,303,349,404,412,513,539,545,596,612,630,650,686,733,829,835,885,887,907,929,1039,1044,1060,1090,1098,1139,1166,1182,1184,1241,1278,1311,1361,1370,1407,1459,1493,1533,1584,1591,1599,1703,1729,1786,1832,1841,1893,1983,2003,2116,2166,2223,2252,2278,2331,2380,2409,2449,2457,2460,2480,2549,2562,2594,2658,2699,2767,2790,2820,2947,3083,3119,3139,3164,3194,3213,3235,3249,3254,3327],"A.":[6,3251],"Lee,":[8],"Although":[10,158,1330,2602,3259],"demyelinating":[11,376,420,1198,3312],"optic":[12,284,298,335,478,492,511,517,643,1210,1235,1305,1319,1490,1504,1573,1582,1884,1890,1947,1962,1986,2000,2429,2501,2507,2580,2883,2988,3021,3127],"neuritis":[13],"(ON)":[14],"is":[15,48,56,373,417,568,573,581,777,797,806,991,1108,1119,1124,1300,1341,1410,1650,1674,1712,1792,1855,1871,1887,1968,2023,2028,2036,2058,2081,2084,2402,2491,2533,2558,2588,2632,2653,2675,2688,2729,2810,2832,2841,2847,2853,2870,2950,3261,3273,3278],"commonly":[16,1596,2634],"associated":[17,599,759,779,1115,1431,1637,1720,1739,1798,1856,1931,1969,2025,2431,3015],"with":[18,171,235,263,337,387,447,535,541,600,625,760,780,788,953,1014,1071,1077,1116,1266,1308,1358,1381,1395,1432,1483,1496,1530,1563,1638,1675,1721,1740,1764,1771,1799,1808,1814,1837,1857,1927,1932,1970,1991,2026,2140,2164,2288,2395,2432,2464,2474,2567,2606,2667,2815,2823,2866,2876,2914,3002,3012,3016,3073,3114,3243],"often":[20,1126,1332,1494],"a":[21,139,150,180,275,311,318,427,475,536,553,574,582,727,852,888,1064,1078,1127,1143,1254,1301,1326,1387,1423,1442,1455,1462,1554,1559,1617,1664,1681,1707,1734,1754,1761,1858,1898,1928,1974,2004,2037,2119,2125,2177,2214,2273,2282,2292,2352,2433,2441,2493,2497,2522,2535,2559,2568,2670,2706,2713,2764,2854,2864,2874,2877,2905,2912,2938,3074,3086,3107,3124,3182,3232,3311],"presenting":[22,1136,2405,2714],"event":[23],"for":[24,116,926,935,1208,1287,1685,1955,2088,2192,2237,2830,2868,2885,2911,2984,3010,3292],"multiple":[25],"sclerosis":[26],"(MS),":[27],"neuroretinitis":[28,47,570,622,653,714,741,756,776,789,954,999,1015,1072,1094,1112,1123,1176,1190,1265,1299,1369,1375,1397,1406,1590,1635,1719,1738,1757,1800,1870,1956,2027,2035,2051,2095,2141,2165,2289,2329,2374,2388,2400,2438,2465,2490,2532,2566,2631,2668,2702,2724,2789,2819,2824,2867,3264,3288,3308],"has":[29,38,623,1206,1376,1628],"traditionally":[30],"been":[31,112,1377],"believed":[32,1450,1651],"to":[33,52,198,224,227,257,351,438,799,880,938,975,977,986,1322,1603,1652,1687,1934,2096,2210,2216,2377,2511,2589,2592,2597,2621,2648,2651,2704,2774,2783,2795,2860,2872,2890,2903,2993,3039,3122,3162,3174,3320],"be":[34,308,426,530,718,1114,1386,1653,1661,1910,1953,2053,2467,2590,2598,2649,2705,2901,2982,2994,3008,3071,3175],"unrelated.":[35],"Recent":[36],"literature":[37,2105],"called":[39,1460,1588],"this":[40,1291,1531,2220,2336,3203],"into":[41,260,533,1402],"question.":[42],"Three":[43],"experts":[44],"debate":[45],"whether":[46,366,2833,3276,3284,3304],"causal":[49],"or":[50,394,487,525,555,1161,1280,1515,1656,1879,1882,2078,2272,2600,2639,2693,2924,2940,2991,2998,3281],"coincidental":[51],"MS.":[53,371,423,761,1056,1081,1105,1117,1408,2029,2098,2212,2421,2827,2886,3247],"PRO:":[54],"Neuroretinitis":[55,572,1409,1649,1766,1802],"Associated":[57,1412],"With":[58,1413],"Multiple":[59,1414],"Sclerosis\u2014T.":[60],"Bakaeva,":[61],"MD,":[62,68],"PhD":[63],"L.":[65,2481],"N.":[66,2482],"Johnson,":[67],"MA":[69],"In":[70,442,494,620,849,945,1057,1297,1418,1783,2213,2296,2351,2656,2757,2928],"the":[71,76,88,102,135,156,167,184,202,249,264,268,289,296,322,333,344,379,399,409,432,456,467,484,491,495,502,506,510,561,565,588,664,673,710,763,771,785,791,801,850,866,912,942,951,969,973,994,1026,1030,1091,1102,1175,1201,1209,1216,1222,1273,1276,1317,1323,1354,1365,1403,1446,1452,1484,1489,1497,1500,1510,1513,1528,1544,1550,1564,1577,1581,1585,1614,1621,1697,1793,1894,1940,1971,2042,2067,2104,2107,2122,2132,2143,2148,2171,2201,2217,2230,2234,2238,2247,2254,2266,2305,2317,2328,2332,2341,2348,2373,2381,2387,2404,2414,2417,2423,2447,2453,2458,2506,2512,2518,2541,2544,2564,2573,2576,2579,2584,2610,2616,2644,2679,2684,2717,2720,2726,2739,2754,2785,2797,2834,2897,2918,2932,2943,2978,3025,3031,3036,3058,3064,3068,3098,3104,3133,3153,3158,3165,3170,3178,3237,3268,3290,3293,3301],"waning":[72],"months":[73,221],"of":[74,183,222,239,292,332,340,378,401,434,440,445,458,469,490,499,509,584,594,659,683,694,699,713,745,766,770,784,804,809,822,846,858,868,890,900,922,931,968,984,998,1009,1025,1029,1032,1067,1080,1088,1093,1104,1148,1155,1172,1189,1200,1215,1218,1228,1257,1260,1272,1303,1313,1348,1350,1353,1356,1368,1393,1405,1437,1488,1499,1527,1561,1570,1605,1623,1634,1666,1689,1700,1706,1718,1736,1743,1756,1773,1788,1822,1869,1897,1924,1946,1973,2039,2044,2050,2062,2069,2071,2076,2094,2109,2114,2124,2134,2136,2160,2170,2180,2200,2229,2285,2298,2307,2319,2343,2354,2363,2407,2416,2420,2425,2462,2472,2499,2546,2555,2604,2626,2646,2663,2672,2681,2709,2723,2741,2748,2788,2800,2802,2968,2986,3076,3093,3097,3132,3136,3155,3167,3246,3270,3287,3296,3303,3307],"2019,":[75],"novel":[77],"severe":[78,3017],"acute":[79,1427,1848,2427],"respiratory":[80,1615],"syndrome":[81,430],"coronavirus":[82],"2":[83,721,830,966,1147,1346,2835,2941,3219],"disease":[84,377,585,1196,1775,1791,1824,1834],"(COVID-19)":[85],"silently":[86],"took":[87],"stage":[89],"waiting":[90],"its":[91],"turn.":[92],"And":[93],"then":[94,1507],"one":[95,107,1040,1167,1250,1716,2362,2553,3092],"by":[96,138,149,398,605,840,894,993,1426,1663,1727,1777,1889,1904,1961,2996],"one,":[97],"it":[98,1107,1340,1384,1461,1589,1594,2057,2587,2858,3150,3260,3272,3277],"gripped":[99],"decimated":[101],"Kent":[103],"(pseudonym)":[104,110],"family,":[105],"save":[106],"member.":[108],"Sarah":[109,130,178,367],"had":[111,161,166,179,219,368,816,861,892,955,1023,1034,1041,1055,1085,1141,1152,1169,1234,1253,1264,1607,2183,2187,2203,2259,2301,2312,2669,3197,3210,3218],"hospitalized,":[113],"but":[114,121,586,1383,1557,1818,1873,2009,2495,2539,2751,2894],"not":[115,127,587,702,758,778,807,1294,1553,1902,2024,2412,2492,2534,2654,2752,2961,3007,3046],"COVID-19.":[117],"She":[118,3129,3172,3180,3230],"seemed":[119],"lucky,":[120],"in":[122,134,204,241,278,314,343,385,408,422,436,551,564,656,663,672,715,729,790,941,950,972,988,1063,1130,1191,1221,1275,1334,1343,1379,1441,1525,1597,1760,1769,1806,1852,1989,2012,2138,2147,2291,2452,2488,2517,2609,2623,2636,2683,2725,2804,3028,3030,3063,3067,3103,3169,3177,3267],"reality,":[123],"good":[124],"luck":[125],"was":[126,131,147,286,300,325,328,654,757,1293,1454,1537,1552,1725,1733,2142,2243,2250,2375,2619,3033,3045,3050,3101,3106,3120,3130,3142,3192,3241],"her":[128,144,194,205,242,315,3156,3189,3207],"friend.":[129],"accidently":[132],"struck":[133],"left":[136,297,1027],"leg":[137,146,229],"baseball":[140],"that":[142,354,482,731,755,775,1007,1020,1049,1111,1122,1146,1205,1451,1481,1535,1549,1593,1631,1659,1758,1787,1876,1886,1919,1950,2022,2033,2131,2146,2168,2198,2207,2256,2265,2335,2361,2399,2471,2527,2531,2647,2813,2821,2845,2862,2921,2931,3221,3263],"afternoon":[143],"right":[145,185,228,243,283,323,334],"hit":[148],"passing":[151],"car":[152],"as":[153,252,391,522,579,1337,1470,1512,1644,1732,1912,1921,2054,2056,2145,2437,2640,2792,2794,2851,2896,3079,3310],"she":[154,218,3147,3195,3209,3214,3217],"crossed":[155],"street.":[157],"both":[159,165,1580,1999],"legs":[160],"sustained":[162],"trauma":[163],"same":[168,2144],"yellowish":[169],"hue":[170],"surrounding":[172,1543],"red":[173],"discoloration,":[174],"x-rays":[175],"soon":[176],"revealed":[177],"compound":[181],"fracture":[182],"leg.":[186,206],"This":[187],"time,":[188],"Sarah's":[189,261],"doctors":[190],"were":[191,214,676,768,824,837,1285,2208,2324,3228],"optimistic":[192],"about":[193,2151,2689,3325],"recovery":[195,3043,3234],"ability":[197],"walk":[199,225,352],"after":[200,832,1101,2047,2059,2073,2111,2176,2304,2369,2386,2942],"stabilizing":[201],"bones":[203],"By":[207,294],"contrast,":[208,295],"almost":[209],"1":[210,828,884],"year":[211,319,878,903],"ago,":[212,320],"they":[213,1958,2156,2196],"less":[215,1812,2585],"sanguine":[216],"when":[217,321,782,1174,1477,2327,2503,3035],"several":[220,1526],"inability":[223,350],"due":[226],"weakness":[230],"simultaneous":[232],"eye":[233,324],"pain":[234],"near":[236],"complete":[237,556,3233],"loss":[238,348,1430,3118],"vision":[240,684,2749],"eye.":[244],"\u201cWow!":[245],"That's":[246],"awesome,\u201d":[247],"said":[248],"medical":[250,361],"students":[251],"each":[253],"got":[254],"their":[255,271,279,735,746,1010,1149,2161,2364],"turn":[256],"look":[258],"deep":[259],"eyes":[262],"light":[265],"emanating":[266],"from":[267,288,560,681,1249,1316,1540,1568,1572,1696,1906,2017,2470,2505,2746],"instrument":[269],"on":[270,740,911,958,1966,2106,2121,2543,2552,2563,2572,2697,2963],"heads":[272],"while":[273],"holding":[274],"20-diopter":[276],"lens":[277],"outstretched":[280],"hands.":[281],"The":[282,360,548,697,982,1465,1503,2731,2828],"nerve":[285,299,512,1306,1583,2508,2581],"pale":[287],"past":[290],"bout":[291,1256],"ON.":[293,651,1258,1351,2064,2476],"very":[301,2468],"plump,":[302],"white":[304],"linear":[305],"residue":[306],"could":[307,717,1053,1113],"seen":[309,2290,2635,2951],"forming":[310,2521],"star-shaped":[312,2523],"appearance":[313,1498],"macula.":[316,345,1545],"About":[317],"affected,":[326],"there":[327,1536,1943,2083,2557,2840,2846,3051],"only":[329,839,2624,2737],"moderate":[330],"swelling":[331,1487,1506,1892,1949,1964,2002,2949,3191],"nerve,":[336],"no":[338,862,1538,2085,2811,2842,3244],"evidence":[339,805,808,1705,1742,1772,1821,2844,3245],"stellate":[341,1472],"exudates":[342,563,688,1439,2770,2960,3014],"Her":[346],"visual":[347,1429,1624,3117],"at":[353,452,865,1344,2158,2316,2738,3186],"time":[355,2318,2740,3188],"resolved":[356,1021],"over":[357,843,1245,3236],"3":[358,919,1008,1051,1074,1083,1150,1225,1232,1262,2199,2257,2310,2322,2662],"months.":[359],"team":[362],"wondered":[363],"out":[364],"loud":[365],"now":[369,3196],"developed":[370,748,793,870,1243,2184,2314,2366,2614,3148],"MS":[372,388,435,448,459,794,871,881,893,940,978,987,1244,1371,2046,2072,2110,2137,2185,2271,2302,2315,2368,2382,2408,2622,2652,2682,2710,2803,2816,2852,2869,3140,3297,3326],"an":[374,418,844,1134,1433,1608,1654,1676,1847,2048,2060,2074,2092,2112,2426,2641,2848,3003,3198,3285,3305],"inflammatory":[375,405,419,1881,2548,2926],"central":[380,1202],"nervous":[381,1203],"system.":[382],"Intraocular":[383],"inflammation":[384,503,1307,2582,2999],"association":[386,1380,1673,1807,2787,3135],"can":[389,425,529,1804,2817,2825,3265],"manifest":[390],"intermediate":[392],"uveitis":[393],"pars":[395,413],"planitis,":[396],"diagnosed":[397],"presence":[400,2123],"retinal":[402,635,637,1457,1541],"periphlebitis":[403],"cellular":[406],"aggregates":[407],"anterior":[410,507,523,641,1849,1925,1984,2040,2077,2428,2443,2475,2500,2578,2617,2987,3019,3126,3137],"vitreous":[411],"plana":[414],"(1).":[415],"ON":[416,424,451,465,500,524,528,716,869,1360,1562,1850,1926,2080,2115,2444,2561,2608,2618,3138],"disorder":[421,1199],"clinically":[428],"isolated":[429,1646],"preceding":[431,466],"diagnosis":[433,468,1079,1103,2671],"up":[437,1602,1686,2773],"20%":[439],"patients.":[441,2806],"addition,":[443,621,946,2929],"38%\u201350%":[444],"patients":[446,747,819,920,1013,1052,1070,1075,1084,1151,1274,1357,1394,1482,1529,1770,1990,2089,2139,2163,2173,2189,2202,2240,2258,2267,2287,2300,2311,2323,2365,2463,2473,2605,2627,2665,2814,2822,3001,3011,3065,3099],"will":[449,473,504,514,3090],"develop":[450,939,1846,2097,2818,2826],"some":[453,1632,2227],"point":[454],"during":[455,706,2753],"course":[457],"(2).":[460],"Among":[461],"individuals":[462],"who":[463,860,1252,2090,3100],"have":[464,474,1017,1054,2270,2339,2904,3123],"MS,":[470,749,781,1131,1382,2593,2615,2673,2791,3149,3271],"most":[471,1794],"(67%)":[472],"normal":[476,956,1238,2149],"appearing":[477],"nerve\u2014so-called":[479],"retrobulbar":[480,2079,2560,2607],"ON\u2014":[481],"affects":[483],"orbital,":[485],"intracanalicular,":[486],"intracranial":[488,646],"segments":[489],"nerve.":[493],"remaining":[496],"one-third":[497],"(33%)":[498],"cases,":[501,1854],"affect":[505],"part":[508],"cause":[515,1998],"visible":[516],"disc":[518,1236,1309,1320,1491,1505,1574,1891,1948,1963,2001,2344,2948,3190],"edema,":[519,1237],"also":[520,1120,1521,1803,1996,2129],"known":[521,1469,1880,2990],"papillitis.":[526],"Anterior":[527],"further":[531,1400],"subdivided":[532],"cases":[534,1188,1226,1233,1349,1633,1916,1923,1945,2014,2985],"normal-appearing":[537],"macula":[538,1324,2513],"those":[540,1261],"concomitant":[542,1708],"subretinal":[543],"fluid":[544,1315,1571,1699],"macular":[546,687,1267,1327,1362,1859,1899,1907,1929,1975,2005,2018,2126,2434,2569,2765,2769,2933,2959,3013,3200],"exudates.":[547],"latter":[549],"condition,":[550],"which":[552,2556,2674,2687,3187],"partial":[554],"\u201cmacular":[557],"star\u201d":[558],"forms":[559],"lipoproteinaceous":[562,1314,2515],"Henle":[566,2519],"layer,":[567],"termed":[569],"(3,4).":[571],"nonspecific":[575],"finding":[576,1129],"however,":[577,1691,1715,2372],"just":[578,2895],"fever":[580],"sign":[583,1302,2406],"etiology":[589,1684],"per":[590,877,902,2153,2691],"se.":[591],"A":[592,1390,1671,2966],"plethora":[593],"diseases":[595,2638],"disorders":[597,627],"are":[598,1636,1694,1867,1944,1959,2771,2781,2836,3318],"neuroretinitis,":[601,639,2308,2355,2759,2915],"principally":[602],"infections":[603,1335,1817,1828,1844],"caused":[604,1776,1903,2995],"viral,":[606],"bacterial":[607],"(particularly":[608,1988],"cat-scratch":[609,1338,1790,1823,2378],"disease),":[610],"fungal,":[611],"helminthic":[613,1843],"agents":[614],"(e.g.,":[615,628],"diffuse":[616],"unilateral":[617,1428,3125],"subacute":[618],"neuroretinitis).":[619],"occurred":[624,1095,1595,1759,2303,2383],"inflammatory/immunologic":[626],"sarcoidosis":[629],"systemic":[631,2448],"lupus":[632],"erythematosus),":[633],"idiopathic":[634,645,1396,2642],"vasculitis,":[636],"aneurysm,":[638],"nonarteritic":[640],"ischemic":[642,1985,3020],"neuropathy,":[644,3022],"hypertension":[647,1995],"(pseudotumor":[648],"cerebri),":[649],"Notably,":[652],"present":[655,1342,2762],"approximately":[657],"2%":[658],"388":[660],"participants":[661,675,787,859,924,933,949,971,1220,1263,3029],"enrolled":[662,677,3066,3102,3176],"Optic":[665],"Neuritis":[666],"Treatment":[667],"Trial":[668],"(ONTT)":[669],"(5\u20137).":[670,909],"However,":[671,2065],"ONTT,":[674,851],"within":[678,691,872,979,2743],"8":[679,786,847,936,948,970,2181,2744],"days":[680,2745],"onset":[682,834,867,1622,2747],"loss,":[685,2750],"typically":[689],"occur":[690,1643,1768,1805,3266],"1\u20133":[692,2775],"weeks":[693,1619,2776,3184],"symptom":[695,833,2708],"onset.":[696],"design":[698,2733],"ONTT":[700,764,792,952,974,1223,2611,2727,3032,3069,3105],"did":[701,1005,1016,2269],"include":[703,1829,1981],"funduscopic":[704,2349,2735],"photographs":[705],"follow-up":[707,2235,2755],"visits.":[708,2756],"Consequently,":[709,961],"true":[711,1366,2721,2786],"incidence":[712,2722],"greater":[719],"than":[720,1133,1780,2440,2678,2712],"percent.":[722],"Parmley":[723,750,812,943,1002,1281,2099],"et":[724,751,813,1003,1179,1282,1750,2100,2357,2397],"al":[725,752,814,1004,1180,1751,2101,2358,2398],"published":[726,737],"report":[728],"1987":[730],"combined":[732,1359],"updated":[734],"previously":[736],"1984":[738],"articles":[739],"(3,8,9).":[742],"Because":[743,1352,1576],"none":[744,783,1242,1271,2169,2297],"(8)":[753,815,2102],"opined":[754],"Subsequently,":[762,2276],"authors\u2014some":[765],"whom":[767,823,1033,1606],"coauthors":[769],"Parmley's":[772],"articles\u2014also":[773],"declared":[774],"(6,7).":[795],"It":[796,1118,1626,2525,3005],"important":[798],"recall":[800],"polemic,":[802],"\u201cAbsence":[803],"absence\u201d":[810],"(10).":[811],"followed":[817,925,934,2190,2241],"23":[818],"prospectively,":[820],"10":[821,895,923,980,1099,2188,2239],"physically":[825],"examined":[826],"between":[827,882,904],"years":[831,874,883,896,905,928,1100,1247,2182,2385,3240],"13":[836,932,2172],"evaluated":[838,1012],"telephone":[841],"interviews":[842],"average":[845],"years.":[848,981],"prospective":[853,1391],"randomized":[854],"cohort":[855],"study,":[856,2231],"16%":[857],"MRI":[863,957,3026],"lesions":[864],"5":[873],"(approximately":[875],"3%":[876],"conversion":[879,898,985],"5)":[886],"total":[889],"22%":[891],"(approximate":[897],"rate":[899,2068,2133],"1%":[901],"6":[906],"10)":[908],"Based":[910,2571,2696],"aforementioned":[913],"data,":[914,2575,2701],"we":[915,962],"would":[916,963,1047,1917,1922,2052],"expect":[917,964],"possibly":[918,965],"(0.3\u20130.6":[921],"1\u20132":[927,2193],"2.4":[930],"years)":[937],"report.":[944],"all":[947],"initial":[959,1135,1239],"examination.":[960],"(22%)":[967],"convert":[976],"absence":[983],"these":[989,1050,1915,2299,2391,2805,3323],"studies":[990,2780,3317],"limited":[992],"small":[995],"sample":[996],"sizes":[997],"cases.":[1000],"Nonetheless,":[1001],"indicate":[1006],"retrospectively":[1011,2175],"neurologic":[1018,2205,2261],"manifestations":[1019],"(2":[1022],"numbness":[1024],"side":[1028],"body\u2014one":[1031],"abnormal":[1035],"somatosensory":[1036],"evoked":[1037],"potential":[1038,1144],"urinary":[1042],"urgency":[1043],"incontinence).":[1045],"We":[1046],"argue":[1048],"2004,":[1058],"Williams":[1059,1138,1277,2277,2657,2698],"Johnson":[1061,1140,1279,1728,2279,2483,3084],"(11)":[1062,2280],"retrospective":[1065,2283],"analysis":[1066],"35":[1068,2286,2664],"consecutive":[1069],"identified":[1073,1224],"(8.6%)":[1076,2666],"All":[1082,1231,2321],"previous":[1086,1153],"episodes":[1087,1092],"ON,":[1089,2041],"1,":[1096],"4,":[1097],"Therefore,":[1106],"certainly":[1109],"possible":[1110,1121,1682,3134],"more":[1125,1331,2577,2595,2633],"late":[1128,2707],"rather":[1132,1558,2439,2496,2540,2711],"event.":[1137],"noted":[1142],"confounder":[1145],"use":[1154,1171],"\u03b2-interferon":[1156,1173,2326],"(Avonex":[1157],"[Biogen,":[1158],"Cambridge":[1159],"MA]":[1160],"Betaseron":[1162],"[Bayer,":[1163],"Leverkusen,":[1164],"Germany])":[1165],"patient":[1168,2454,2865,2875,2899,2913,2944,3087],"concurrent":[1170,1495],"developed.":[1177],"Moura":[1178],"(12)":[1181],"Lee":[1183,3253],"El-Dairi":[1185],"(13)":[1186],"described":[1187,1422],"myelin":[1192,1935],"oligodendrocyte":[1193,1936],"glycoprotein":[1194,1937],"antibody\u2013associated":[1195],"(MOGAD)\u2014another":[1197],"system":[1204],"predilection":[1207],"pathways.":[1211],"An":[1212],"independent":[1213],"study":[1214,1392,2732],"serum":[1217],"177":[1219],"(1.7%)":[1227],"MOGAD":[1229],"(14).":[1230],"MRI,":[1240],"15":[1246,3239],"apart":[1248],"participant":[1251],"recurrent":[1255],"None":[1259],"star":[1268,1328,1363,1443,1501,1565,1860,1900,1930,1976,2006,2435,2934],"formation.":[1269,1329],"Regrettably,":[1270],"al's":[1283],"series":[1284,2249,2612,2661,2728],"tested":[1286],"MOG":[1288],"antibody":[1289],"because":[1290,2034,3145],"test":[1292],"yet":[1295,3047],"available.":[1296],"summary,":[1298],"significant":[1304],"edema":[1310,2504],"leakage":[1312,1539,1905,2016],"peripapillary":[1318],"vessels":[1321,1542,1908],"causing":[1325],"observed":[1333,2772],"such":[1336,1701,1864,2013],"disease,":[1339,2379],"least":[1345],"percent":[1347],"scarcity":[1355],"formation,":[1364],"relationship":[1367],"remains":[1372,3298,3314],"uncertain.":[1373],"Nevertheless,":[1374],"reported":[1378,1480,1726,1753],"may":[1385,1398,1660,1767,1845,1997,2761,2956],"later":[1388],"manifestation.":[1389],"provide":[1399,3091],"insights":[1401],"correlation":[1404],"Not":[1411],"Sclerosis\u2014Neil":[1415],"Miller,":[1416],"1916,":[1419],"T.":[1420,2478],"Leber":[1421,1449,1471],"condition":[1424,1453,1466,1485,1532,1551,1578,2021],"characterized":[1425,1888,1960],"exudative":[1434],"maculopathy":[1435,1473,1511],"consisting":[1436],"hard":[1438],"arranged":[1440],"figure":[1444,1566,1861,1901,2007,2436,2935],"around":[1445],"fovea":[1447],"(15).":[1448],"primary":[1456,1514,1555],"process":[1458,1658,1797,2907],"\u201cstellate":[1463],"maculopathy.\u201d":[1464],"subsequently":[1467,1627],"became":[1468],"(16)":[1474],"until":[1475,2908],"1977,":[1476,2489],"Gass":[1478,1519,2485],"(17)":[1479,1520,2486],"showed":[1486,1534],"before":[1492,1620],"figure.":[1502,1977,2524],"resolved,":[1508],"leaving":[1509,2514],"sole":[1516],"ophthalmoscopic":[1517],"abnormality.":[1518],"performed":[1522,2281,3027],"fluorescein":[1523,2010],"angiography":[1524,2011],"He":[1546],"thus":[1547,2346],"concluded":[1548],"maculopathy,":[1556,2494],"form":[1560,2038,2498],"occurring":[1567],"spread":[1569],"vessels.":[1575,2019],"affected":[1579],"retina,":[1586],"he":[1587],"emphasized":[1592,2226],"children":[1598],"young":[1600,1762,3108],"adults,":[1601],"50%":[1604,1688],"antecedent":[1609,1677],"viral":[1610,1678,1683,1709],"illness,":[1611],"usually":[1612,1711,2936],"affecting":[1613,2347],"tract,":[1616],"few":[1618,3183],"symptoms.":[1625],"become":[1629],"clear":[1630,3262],"infectious":[1639,1655,1774,1796,1883,2550,2599,2637,2923],"diseases,":[1640],"whereas":[1641],"others":[1642],"apparently":[1645],"phenomena":[1647],"(3,4,9,18,19).":[1648],"immune-mediated":[1657],"precipitated":[1662],"number":[1665],"different":[1667,2469],"agents,":[1668],"including":[1669],"viruses.":[1670],"common":[1672,1795,1827,2855],"syndrome,":[1679],"suggesting":[1680],"cases;":[1690],"viruses":[1692,1781],"rarely":[1693,2117],"cultured":[1695],"cerebrospinal":[1698],"patients,":[1702],"serologic":[1704,1741],"infection":[1710,1747,2997],"absent":[1713],"(3,9,17);":[1714],"case":[1717,1735,1755],"herpes":[1722],"simplex":[1723],"encephalitis":[1724],"Wisotzkey":[1730],"(20),":[1731],"bilateral":[1737],"hepatitis":[1744],"B":[1745],"virus":[1746],"(21).":[1748],"Foster":[1749],"(22)":[1752],"man":[1763],"mumps.":[1765],"organisms":[1778],"other":[1779,1941,2565,2718,2969],"(18,19,23).":[1782],"my":[1784,3080,3094],"experience":[1785,2091],"others,":[1789],"(4,19).":[1801],"Bartonella":[1809,3226],"henselae":[1810],"and,":[1811],"frequently,":[1813],"B.":[1815],"quintana":[1816],"without":[1819,2763],"clinical":[1820,2964],"(24).":[1825],"Other":[1826],"syphilis":[1830],"(25\u201328)":[1831],"Lyme":[1833],"(29).":[1835],"Patients":[1836],"toxoplasmosis,":[1838],"toxocariasis,":[1839],"histoplasmosis,":[1840],"even":[1842],"that,":[1851,1965],"rare":[1853],"(30\u201334).":[1862],"Whether":[1863],"conditions":[1865,1980],"truly":[1866],"examples":[1868],"unclear,":[1872],"I":[1874,2393,2976,3089,3205],"believe":[1875,2977],"any":[1877,3052,3211],"presumed":[1878],"neuropathy":[1885,1987,2430,2502,2884,2989],"eventual":[1895],"development":[1896,1972,2070,2108,2135,2419,2801,3295],"should":[1909,1951,2466,2900,2981,3006],"defined":[1911],"neuroretinitis;":[1913,2371],"thus,":[1914],"fit":[1918],"description":[1920],"antibodies":[1933],"(12,13).":[1938],"On":[1939,2716],"hand,":[1942,2719],"never":[1952,2403],"mistaken":[1954],"although":[1957,2066,2195,2309,2630],"occasion,":[1967],"These":[1978],"mimicking":[1979],"papilledema":[1982],"diabetes":[1992],"mellitus).":[1993],"Systemic":[1994],"(35),":[2008],"shows":[2015],"One":[2020,2030,3096],"might":[2031,2263,2338,3151],"assume":[2032],"likelihood":[2043,2645],"developing":[2045],"attack":[2049,2061,2075,2093,2113,3313],"high":[2055],"straightforward":[2063],"substantial,":[2082],"increased":[2086],"tendency":[2087],"reviewed":[2103],"found":[2118,2167,3121],"comment":[2120],"star.":[2127,2570,3201],"They":[2128],"calculated":[2130],"population,":[2150,2686],"6\u201380":[2152],"100,000.":[2154],"Finally,":[2155,3078],"looked":[2157],"50":[2159],"own":[2162],"contacted":[2174],"mean":[2178,3152],"period":[2179,2236],"nor":[2186,3049],"prospectively":[2191,2242],"years,":[2194],"stated":[2197,2360],"\u201cother":[2204,2260],"manifestations\u201d":[2206,2262],"insufficient":[2209],"diagnose":[2211],"letter":[2215],"editor":[2218],"regarding":[2219],"article,":[2221],"Wilson":[2222],"Smith":[2224],"(36)":[2225],"limitations":[2228],"namely":[2232],"1)":[2233,2401],"somewhat":[2244],"short,":[2245],"2)":[2246,2410],"authors'":[2248],"small,":[2251],"3)":[2253],"fact":[2255],"suggest":[2264],"really":[2268],"similar":[2274,2871],"process.":[2275],"review":[2284,2353],"single":[2293],"university-based":[2294],"practice.":[2295],"occurrence":[2306],"already":[2313],"diagnosis.":[2320],"taking":[2325],"occurred,":[2330],"authors":[2333],"suggested":[2334],"treatment":[2337,3159],"influenced":[2340],"permeability":[2342],"vessels,":[2345],"appearance.":[2350],"Purvin":[2356,2396],"(4)":[2359],"relapsing-remitting":[2367],"experiencing":[2370],"attributed":[2376],"11":[2384],"occurred.":[2389],"For":[2390],"reasons,":[2392],"agree":[2394],"does":[2411],"increase":[2413],"risk":[2415,2799,3291],"subsequent":[2418],"Thus,":[2422,3057],"designation":[2424],"\u201ctypical\u201d":[2442],"substantially":[2445],"alters":[2446],"neurological":[2450],"prognoses":[2451],"being":[2455],"evaluated,":[2456],"evaluation":[2459],"management":[2461],"Rebuttal\u2014Drs.":[2477],"Bakaeva":[2479,3082],"As":[2484],"postulated":[2487],"head":[2509],"spreads":[2510],"material":[2516,3055],"layer":[2520],"seems":[2526,2703,2859],"Dr.":[2528],"Miller":[2529,2808],"agrees":[2530],"separate":[2536],"pathological":[2537],"entity":[2538],"extreme":[2542],"spectrum":[2545],"neuro-ophthalmological":[2547],"disorders,":[2551],"end":[2554,3154],"available":[2574,3048,3161],"occurs,":[2583],"likely":[2586,2596],"related":[2591,2620,2650,3280],"idiopathic:":[2601],"31%":[2603],"eventually":[2613],"14%":[2625],"(7).":[2628],"Likewise,":[2629],"entity,":[2643],"zero:":[2655],"Johnson's":[2659,2700],"(11),":[2660],"much":[2676],"higher":[2677],"prevalence":[2680],"US":[2685],"300":[2690],"100,000":[2692],"0.3%":[2694],"(37).":[2695],"feature.":[2715],"unknown:":[2730],"included":[2734],"examination":[2736],"enrollment,":[2742],"early":[2758,2958],"papillitis":[2760],"star,":[2766],"typical":[2768],"later.":[2777],"More":[2778],"longitudinal":[2779],"needed":[2782,3319],"characterize":[2784],"well":[2793,3242],"determine":[2796],"exact":[2798],"Rebuttal\u2014Dr.":[2807],"There":[2809],"question":[2812,3302],"issue":[2829],"me":[2831,2861,3216],"related.":[2837],"To":[2838],"date,":[2839],"convincing":[2843],"association,":[2849],"particularly":[2850,3144],"disorder.":[2856],"Indeed,":[2857],"evaluating":[2863,2873],"unilateral,":[2878],"insidious":[2879],"onset,":[2880],"slowly":[2881],"progressive":[2882],"If":[2887],"you":[2888],"want":[2889],"do":[2891],"it,":[2892],"fine,":[2893],"first":[2898,2916],"considered":[2902],"compressive":[2906],"proven":[2909],"otherwise,":[2910],"consider":[2917],"\u201cusual":[2919],"suspects,\u201d":[2920],"is,":[2922],"non-MS":[2925],"causes!":[2927],"remember":[2930],"develops":[2937],"week":[2939],"becomes":[2945],"symptomatic":[2946],"(although":[2952],"optical":[2953],"coherence":[2954],"tomography":[2955],"show":[2957],"obvious":[2962,3199],"examination).":[2965],"couple":[2967],"points":[2970],"require":[2971],"emphasis":[2972],"(or":[2973,3060],"re-emphasis).":[2974],"First,":[2975],"term":[2979],"\u201cneuroretinitis\u201d":[2980],"reserved":[2983],"suspected":[2992],"(i.e.,":[3000],"ON).":[3004],"used":[3009,3038],"papilledema,":[3018],"etc.":[3023],"Second,":[3024],"done":[3034],"software":[3037],"obtain":[3040],"fluid-attenuated":[3041],"inversion":[3042],"images":[3044],"paramagnetic":[3053],"contrast":[3054],"used.":[3056],"findings":[3059],"lack":[3061],"thereof)":[3062],"must":[3070],"taken":[3072],"grain":[3075],"salt.":[3077],"colleagues":[3081],"contributed":[3085],"anecdote,":[3088],"own.":[3095],"woman\u2014a":[3109],"professional":[3110],"ice":[3111],"skater\u2014who":[3112],"presented":[3113],"acute,":[3115],"monocular":[3116],"neuropathy.":[3128],"told":[3131,3215],"(she":[3141],"devastated,":[3143],"if":[3146,3208],"career),":[3157],"options":[3160],"her,":[3163],"option":[3166],"participating":[3168],"ONTT.":[3171,3179],"agreed":[3173],"returned":[3181],"later,":[3185],"resolving":[3193],"At":[3202],"point,":[3204],"asked":[3206]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2021-12-31T00:00:00"}