{"id":"https://openalex.org/W4200325630","doi":"https://doi.org/10.35627/2219-5238/2021-29-11-76-82","title":"On the Mechanism of Development of Autoimmune Diseases Following Exposure to Inactivated Mycobacterium tuberculosis","display_name":"On the Mechanism of Development of Autoimmune Diseases Following Exposure to Inactivated Mycobacterium tuberculosis","publication_year":2021,"publication_date":"2021-11-01","ids":{"openalex":"https://openalex.org/W4200325630","doi":"https://doi.org/10.35627/2219-5238/2021-29-11-76-82"},"language":"en","primary_location":{"id":"doi:10.35627/2219-5238/2021-29-11-76-82","doi":"https://doi.org/10.35627/2219-5238/2021-29-11-76-82","is_oa":true,"landing_page_url":"https://doi.org/10.35627/2219-5238/2021-29-11-76-82","pdf_url":"https://zniso.fcgie.ru/jour/article/download/728/592","source":{"id":"https://openalex.org/S4210169498","display_name":"\u0417\u0414\u041e\u0420\u041e\u0412\u042c\u0415 \u041d\u0410\u0421\u0415\u041b\u0415\u041d\u0418\u042f \u0418 \u0421\u0420\u0415\u0414\u0410 \u041e\u0411\u0418\u0422\u0410\u041d\u0418\u042f - \u0417\u041d\u0438\u0421\u041e / PUBLIC HEALTH AND LIFE ENVIRONMENT","issn_l":"2219-5238","issn":["2219-5238","2619-0788"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["russia-white-list-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"\u0417\u0414\u041e\u0420\u041e\u0412\u042c\u0415 \u041d\u0410\u0421\u0415\u041b\u0415\u041d\u0418\u042f \u0418 \u0421\u0420\u0415\u0414\u0410 \u041e\u0411\u0418\u0422\u0410\u041d\u0418\u042f - \u0417\u041d\u0438\u0421\u041e / PUBLIC HEALTH AND LIFE ENVIRONMENT","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://zniso.fcgie.ru/jour/article/download/728/592","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048605649","display_name":"S.V. Skupnevskiy","orcid":"https://orcid.org/0000-0002-6233-5944","observed_orcids":["https://orcid.org/0000-0002-6233-5944"]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210131691","display_name":"Federal State Budgetary Institution of Science Federal Scientific Center \"Vladikavkaz Scientific Center of the Russian Academy of Sciences\"","ror":"https://ror.org/02v9hwv19","country_code":"RU","type":"government","lineage":["https://openalex.org/I4210131691"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"SV Skupnevskiy","raw_affiliation_strings":["Institute of Biomedical Research -Affiliate of Vladikavkaz Scientific Center of RAS , 47 Pushkinskaya Street , Vladikavkaz , RNO-Alania , 362025 , Russian Federation","\u0418\u043d\u0441\u0442\u0438\u0442\u0443\u0442 \u0431\u0438\u043e\u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0438\u0445 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0439 \u2013 \u0444\u0438\u043b\u0438\u0430\u043b \u0424\u0413\u0411\u0423\u041d \u0424\u0435\u0434\u0435\u0440\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u043d\u0430\u0443\u0447\u043d\u043e\u0433\u043e \u0446\u0435\u043d\u0442\u0440\u0430 \u00ab\u0412\u043b\u0430\u0434\u0438\u043a\u0430\u0432\u043a\u0430\u0437\u0441\u043a\u0438\u0439 \u043d\u0430\u0443\u0447\u043d\u044b\u0439 \u0446\u0435\u043d\u0442\u0440 \u0420\u043e\u0441\u0441\u0438\u0439\u0441\u043a\u043e\u0439 \u0430\u043a\u0430\u0434\u0435\u043c\u0438\u0438 \u043d\u0430\u0443\u043a\u00bb"],"raw_orcid":"https://orcid.org/0000-0002-6233-5944","affiliations":[{"raw_affiliation_string":"Institute of Biomedical Research -Affiliate of Vladikavkaz Scientific Center of RAS , 47 Pushkinskaya Street , Vladikavkaz , RNO-Alania , 362025 , Russian Federation","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210131691"]},{"raw_affiliation_string":"\u0418\u043d\u0441\u0442\u0438\u0442\u0443\u0442 \u0431\u0438\u043e\u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0438\u0445 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0439 \u2013 \u0444\u0438\u043b\u0438\u0430\u043b \u0424\u0413\u0411\u0423\u041d \u0424\u0435\u0434\u0435\u0440\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u043d\u0430\u0443\u0447\u043d\u043e\u0433\u043e \u0446\u0435\u043d\u0442\u0440\u0430 \u00ab\u0412\u043b\u0430\u0434\u0438\u043a\u0430\u0432\u043a\u0430\u0437\u0441\u043a\u0438\u0439 \u043d\u0430\u0443\u0447\u043d\u044b\u0439 \u0446\u0435\u043d\u0442\u0440 \u0420\u043e\u0441\u0441\u0438\u0439\u0441\u043a\u043e\u0439 \u0430\u043a\u0430\u0434\u0435\u043c\u0438\u0438 \u043d\u0430\u0443\u043a\u00bb","institution_ids":["https://openalex.org/I4210131691"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112688513","display_name":"GM Trukhina","orcid":"https://orcid.org/0000-0001-9955-7447","observed_orcids":["https://orcid.org/0000-0001-9955-7447"]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210131691","display_name":"Federal State Budgetary Institution of Science Federal Scientific Center \"Vladikavkaz Scientific Center of the Russian Academy of Sciences\"","ror":"https://ror.org/02v9hwv19","country_code":"RU","type":"government","lineage":["https://openalex.org/I4210131691"]},{"id":"https://openalex.org/I4210145347","display_name":"Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing","ror":"https://ror.org/03bczw616","country_code":"RU","type":"government","lineage":["https://openalex.org/I4210145347"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"GM Trukhina","raw_affiliation_strings":["Dr. Sci. (Biol.) , Leading Researcher , Laboratory of Subcellular Structures , Department of Molecular and Cellular Mechanisms of Autoimmune Diseases , Institute of Biomedical Research , Affiliate of Vladikavkaz Scientific Center of the Russian Academy of Sciences ;","Head of Microbiological Laboratory , Federal Scientific Center of Hygiene named after F.F ","\u0424\u0411\u0423\u041d \u00ab\u0424\u0435\u0434\u0435\u0440\u0430\u043b\u044c\u043d\u044b\u0439 \u043d\u0430\u0443\u0447\u043d\u044b\u0439 \u0446\u0435\u043d\u0442\u0440 \u0433\u0438\u0433\u0438\u0435\u043d\u044b \u0438\u043c. \u0424.\u0424. \u042d\u0440\u0438\u0441\u043c\u0430\u043d\u0430\u00bb \u0420\u043e\u0441\u043f\u043e\u0442\u0440\u0435\u0431\u043d\u0430\u0434\u0437\u043e\u0440\u0430"],"raw_orcid":"https://orcid.org/0000-0001-9955-7447","affiliations":[{"raw_affiliation_string":"Dr. Sci. (Biol.) , Leading Researcher , Laboratory of Subcellular Structures , Department of Molecular and Cellular Mechanisms of Autoimmune Diseases , Institute of Biomedical Research , Affiliate of Vladikavkaz Scientific Center of the Russian Academy of Sciences ;","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210131691"]},{"raw_affiliation_string":"Head of Microbiological Laboratory , Federal Scientific Center of Hygiene named after F.F ","institution_ids":[]},{"raw_affiliation_string":"\u0424\u0411\u0423\u041d \u00ab\u0424\u0435\u0434\u0435\u0440\u0430\u043b\u044c\u043d\u044b\u0439 \u043d\u0430\u0443\u0447\u043d\u044b\u0439 \u0446\u0435\u043d\u0442\u0440 \u0433\u0438\u0433\u0438\u0435\u043d\u044b \u0438\u043c. \u0424.\u0424. \u042d\u0440\u0438\u0441\u043c\u0430\u043d\u0430\u00bb \u0420\u043e\u0441\u043f\u043e\u0442\u0440\u0435\u0431\u043d\u0430\u0434\u0437\u043e\u0440\u0430","institution_ids":["https://openalex.org/I4210145347"]}]},{"author_position":"middle","author":{"id":null,"display_name":"EG Pukhaeva","orcid":"https://orcid.org/0000-0002-0850-2537","observed_orcids":["https://orcid.org/0000-0002-0850-2537"]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210131691","display_name":"Federal State Budgetary Institution of Science Federal Scientific Center \"Vladikavkaz Scientific Center of the Russian Academy of Sciences\"","ror":"https://ror.org/02v9hwv19","country_code":"RU","type":"government","lineage":["https://openalex.org/I4210131691"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"EG Pukhaeva","raw_affiliation_strings":["Dr. Sci. (Biol.) , Leading Researcher , Laboratory of Subcellular Structures , Department of Molecular and Cellular Mechanisms of Autoimmune Diseases , Institute of Biomedical Research , Affiliate of Vladikavkaz Scientific Center of the Russian Academy of Sciences ;","\u0418\u043d\u0441\u0442\u0438\u0442\u0443\u0442 \u0431\u0438\u043e\u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0438\u0445 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0439 \u2013 \u0444\u0438\u043b\u0438\u0430\u043b \u0424\u0413\u0411\u0423\u041d \u0424\u0435\u0434\u0435\u0440\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u043d\u0430\u0443\u0447\u043d\u043e\u0433\u043e \u0446\u0435\u043d\u0442\u0440\u0430 \u00ab\u0412\u043b\u0430\u0434\u0438\u043a\u0430\u0432\u043a\u0430\u0437\u0441\u043a\u0438\u0439 \u043d\u0430\u0443\u0447\u043d\u044b\u0439 \u0446\u0435\u043d\u0442\u0440 \u0420\u043e\u0441\u0441\u0438\u0439\u0441\u043a\u043e\u0439 \u0430\u043a\u0430\u0434\u0435\u043c\u0438\u0438 \u043d\u0430\u0443\u043a\u00bb"],"raw_orcid":"https://orcid.org/0000-0002-0850-2537","affiliations":[{"raw_affiliation_string":"Dr. Sci. (Biol.) , Leading Researcher , Laboratory of Subcellular Structures , Department of Molecular and Cellular Mechanisms of Autoimmune Diseases , Institute of Biomedical Research , Affiliate of Vladikavkaz Scientific Center of the Russian Academy of Sciences ;","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210131691"]},{"raw_affiliation_string":"\u0418\u043d\u0441\u0442\u0438\u0442\u0443\u0442 \u0431\u0438\u043e\u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0438\u0445 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0439 \u2013 \u0444\u0438\u043b\u0438\u0430\u043b \u0424\u0413\u0411\u0423\u041d \u0424\u0435\u0434\u0435\u0440\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u043d\u0430\u0443\u0447\u043d\u043e\u0433\u043e \u0446\u0435\u043d\u0442\u0440\u0430 \u00ab\u0412\u043b\u0430\u0434\u0438\u043a\u0430\u0432\u043a\u0430\u0437\u0441\u043a\u0438\u0439 \u043d\u0430\u0443\u0447\u043d\u044b\u0439 \u0446\u0435\u043d\u0442\u0440 \u0420\u043e\u0441\u0441\u0438\u0439\u0441\u043a\u043e\u0439 \u0430\u043a\u0430\u0434\u0435\u043c\u0438\u0438 \u043d\u0430\u0443\u043a\u00bb","institution_ids":["https://openalex.org/I4210131691"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057847571","display_name":"A. K. Badtiev","orcid":"https://orcid.org/0000-0001-5850-5173","observed_orcids":["https://orcid.org/0000-0001-5850-5173"]},"institutions":[{"id":"https://openalex.org/I4210131691","display_name":"Federal State Budgetary Institution of Science Federal Scientific Center \"Vladikavkaz Scientific Center of the Russian Academy of Sciences\"","ror":"https://ror.org/02v9hwv19","country_code":"RU","type":"government","lineage":["https://openalex.org/I4210131691"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"AK Badtiev","raw_affiliation_strings":["Cand. Sci. (Biol.) , Senior Researcher , Laboratory of Subcellular Structures , Department of Molecular and Cellular Mechanisms of Autoimmune Diseases , Institute of Biomedical Research , Affiliate of Vladikavkaz Scientific Center of RAS ;","Junior Researcher , Laboratory of Subcellular Structures , Department of Molecular and Cellular Mechanisms of Autoimmune Diseases , Institute of Biomedical Research , Affiliate of Vladikavkaz Scientific Center of RAS ;","\u0418\u043d\u0441\u0442\u0438\u0442\u0443\u0442 \u0431\u0438\u043e\u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0438\u0445 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0439 \u2013 \u0444\u0438\u043b\u0438\u0430\u043b \u0424\u0413\u0411\u0423\u041d \u0424\u0435\u0434\u0435\u0440\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u043d\u0430\u0443\u0447\u043d\u043e\u0433\u043e \u0446\u0435\u043d\u0442\u0440\u0430 \u00ab\u0412\u043b\u0430\u0434\u0438\u043a\u0430\u0432\u043a\u0430\u0437\u0441\u043a\u0438\u0439 \u043d\u0430\u0443\u0447\u043d\u044b\u0439 \u0446\u0435\u043d\u0442\u0440 \u0420\u043e\u0441\u0441\u0438\u0439\u0441\u043a\u043e\u0439 \u0430\u043a\u0430\u0434\u0435\u043c\u0438\u0438 \u043d\u0430\u0443\u043a\u00bb"],"raw_orcid":"https://orcid.org/0000-0001-5850-5173","affiliations":[{"raw_affiliation_string":"Cand. Sci. (Biol.) , Senior Researcher , Laboratory of Subcellular Structures , Department of Molecular and Cellular Mechanisms of Autoimmune Diseases , Institute of Biomedical Research , Affiliate of Vladikavkaz Scientific Center of RAS ;","institution_ids":["https://openalex.org/I4210131691"]},{"raw_affiliation_string":"Junior Researcher , Laboratory of Subcellular Structures , Department of Molecular and Cellular Mechanisms of Autoimmune Diseases , Institute of Biomedical Research , Affiliate of Vladikavkaz Scientific Center of RAS ;","institution_ids":["https://openalex.org/I4210131691"]},{"raw_affiliation_string":"\u0418\u043d\u0441\u0442\u0438\u0442\u0443\u0442 \u0431\u0438\u043e\u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0438\u0445 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0439 \u2013 \u0444\u0438\u043b\u0438\u0430\u043b \u0424\u0413\u0411\u0423\u041d \u0424\u0435\u0434\u0435\u0440\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u043d\u0430\u0443\u0447\u043d\u043e\u0433\u043e \u0446\u0435\u043d\u0442\u0440\u0430 \u00ab\u0412\u043b\u0430\u0434\u0438\u043a\u0430\u0432\u043a\u0430\u0437\u0441\u043a\u0438\u0439 \u043d\u0430\u0443\u0447\u043d\u044b\u0439 \u0446\u0435\u043d\u0442\u0440 \u0420\u043e\u0441\u0441\u0438\u0439\u0441\u043a\u043e\u0439 \u0430\u043a\u0430\u0434\u0435\u043c\u0438\u0438 \u043d\u0430\u0443\u043a\u00bb","institution_ids":["https://openalex.org/I4210131691"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070659416","display_name":"Fatima K. Rurua","orcid":"https://orcid.org/0000-0001-9424-0467","observed_orcids":["https://orcid.org/0000-0001-9424-0467"]},"institutions":[{"id":"https://openalex.org/I4210131691","display_name":"Federal State Budgetary Institution of Science Federal Scientific Center \"Vladikavkaz Scientific Center of the Russian Academy of Sciences\"","ror":"https://ror.org/02v9hwv19","country_code":"RU","type":"government","lineage":["https://openalex.org/I4210131691"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"FK Rurua","raw_affiliation_strings":["Cand. Sci. (Biol.) , Senior Researcher , Laboratory of Subcellular Structures , Department of Molecular and Cellular Mechanisms of Autoimmune Diseases , Institute of Biomedical Research , Affiliate of Vladikavkaz Scientific Center of RAS ;","Junior Researcher , Laboratory of Subcellular Structures , Department of Molecular and Cellular Mechanisms of Autoimmune Diseases , Institute of Biomedical Research , Affiliate of Vladikavkaz Scientific Center of RAS ;","\u0418\u043d\u0441\u0442\u0438\u0442\u0443\u0442 \u0431\u0438\u043e\u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0438\u0445 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0439 \u2013 \u0444\u0438\u043b\u0438\u0430\u043b \u0424\u0413\u0411\u0423\u041d \u0424\u0435\u0434\u0435\u0440\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u043d\u0430\u0443\u0447\u043d\u043e\u0433\u043e \u0446\u0435\u043d\u0442\u0440\u0430 \u00ab\u0412\u043b\u0430\u0434\u0438\u043a\u0430\u0432\u043a\u0430\u0437\u0441\u043a\u0438\u0439 \u043d\u0430\u0443\u0447\u043d\u044b\u0439 \u0446\u0435\u043d\u0442\u0440 \u0420\u043e\u0441\u0441\u0438\u0439\u0441\u043a\u043e\u0439 \u0430\u043a\u0430\u0434\u0435\u043c\u0438\u0438 \u043d\u0430\u0443\u043a\u00bb"],"raw_orcid":"https://orcid.org/0000-0001-9424-0467","affiliations":[{"raw_affiliation_string":"Cand. Sci. (Biol.) , Senior Researcher , Laboratory of Subcellular Structures , Department of Molecular and Cellular Mechanisms of Autoimmune Diseases , Institute of Biomedical Research , Affiliate of Vladikavkaz Scientific Center of RAS ;","institution_ids":["https://openalex.org/I4210131691"]},{"raw_affiliation_string":"Junior Researcher , Laboratory of Subcellular Structures , Department of Molecular and Cellular Mechanisms of Autoimmune Diseases , Institute of Biomedical Research , Affiliate of Vladikavkaz Scientific Center of RAS ;","institution_ids":["https://openalex.org/I4210131691"]},{"raw_affiliation_string":"\u0418\u043d\u0441\u0442\u0438\u0442\u0443\u0442 \u0431\u0438\u043e\u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0438\u0445 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0439 \u2013 \u0444\u0438\u043b\u0438\u0430\u043b \u0424\u0413\u0411\u0423\u041d \u0424\u0435\u0434\u0435\u0440\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u043d\u0430\u0443\u0447\u043d\u043e\u0433\u043e \u0446\u0435\u043d\u0442\u0440\u0430 \u00ab\u0412\u043b\u0430\u0434\u0438\u043a\u0430\u0432\u043a\u0430\u0437\u0441\u043a\u0438\u0439 \u043d\u0430\u0443\u0447\u043d\u044b\u0439 \u0446\u0435\u043d\u0442\u0440 \u0420\u043e\u0441\u0441\u0438\u0439\u0441\u043a\u043e\u0439 \u0430\u043a\u0430\u0434\u0435\u043c\u0438\u0438 \u043d\u0430\u0443\u043a\u00bb","institution_ids":["https://openalex.org/I4210131691"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044208246","display_name":"F.E. Batagova","orcid":"https://orcid.org/0000-0001-9105-0350","observed_orcids":["https://orcid.org/0000-0001-9105-0350"]},"institutions":[{"id":"https://openalex.org/I4210131691","display_name":"Federal State Budgetary Institution of Science Federal Scientific Center \"Vladikavkaz Scientific Center of the Russian Academy of Sciences\"","ror":"https://ror.org/02v9hwv19","country_code":"RU","type":"government","lineage":["https://openalex.org/I4210131691"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"FE Batagova","raw_affiliation_strings":["Cand. Sci. (Biol.) , Senior Researcher , Laboratory of Subcellular Structures , Department of Molecular and Cellular Mechanisms of Autoimmune Diseases , Institute of Biomedical Research , Affiliate of Vladikavkaz Scientific Center of RAS ;","\u0418\u043d\u0441\u0442\u0438\u0442\u0443\u0442 \u0431\u0438\u043e\u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0438\u0445 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0439 \u2013 \u0444\u0438\u043b\u0438\u0430\u043b \u0424\u0413\u0411\u0423\u041d \u0424\u0435\u0434\u0435\u0440\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u043d\u0430\u0443\u0447\u043d\u043e\u0433\u043e \u0446\u0435\u043d\u0442\u0440\u0430 \u00ab\u0412\u043b\u0430\u0434\u0438\u043a\u0430\u0432\u043a\u0430\u0437\u0441\u043a\u0438\u0439 \u043d\u0430\u0443\u0447\u043d\u044b\u0439 \u0446\u0435\u043d\u0442\u0440 \u0420\u043e\u0441\u0441\u0438\u0439\u0441\u043a\u043e\u0439 \u0430\u043a\u0430\u0434\u0435\u043c\u0438\u0438 \u043d\u0430\u0443\u043a\u00bb"],"raw_orcid":"https://orcid.org/0000-0001-9105-0350","affiliations":[{"raw_affiliation_string":"Cand. Sci. (Biol.) , Senior Researcher , Laboratory of Subcellular Structures , Department of Molecular and Cellular Mechanisms of Autoimmune Diseases , Institute of Biomedical Research , Affiliate of Vladikavkaz Scientific Center of RAS ;","institution_ids":["https://openalex.org/I4210131691"]},{"raw_affiliation_string":"\u0418\u043d\u0441\u0442\u0438\u0442\u0443\u0442 \u0431\u0438\u043e\u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0438\u0445 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0439 \u2013 \u0444\u0438\u043b\u0438\u0430\u043b \u0424\u0413\u0411\u0423\u041d \u0424\u0435\u0434\u0435\u0440\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u043d\u0430\u0443\u0447\u043d\u043e\u0433\u043e \u0446\u0435\u043d\u0442\u0440\u0430 \u00ab\u0412\u043b\u0430\u0434\u0438\u043a\u0430\u0432\u043a\u0430\u0437\u0441\u043a\u0438\u0439 \u043d\u0430\u0443\u0447\u043d\u044b\u0439 \u0446\u0435\u043d\u0442\u0440 \u0420\u043e\u0441\u0441\u0438\u0439\u0441\u043a\u043e\u0439 \u0430\u043a\u0430\u0434\u0435\u043c\u0438\u0438 \u043d\u0430\u0443\u043a\u00bb","institution_ids":["https://openalex.org/I4210131691"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5070467514","display_name":"Zh. G. Farnieva","orcid":"https://orcid.org/0000-0002-9154-4729","observed_orcids":["https://orcid.org/0000-0002-9154-4729"]},"institutions":[{"id":"https://openalex.org/I4210131691","display_name":"Federal State Budgetary Institution of Science Federal Scientific Center \"Vladikavkaz Scientific Center of the Russian Academy of Sciences\"","ror":"https://ror.org/02v9hwv19","country_code":"RU","type":"government","lineage":["https://openalex.org/I4210131691"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"ZhG Farnieva","raw_affiliation_strings":["Cand. Sci. (Biol.) , Senior Researcher , Laboratory of Subcellular Structures , Department of Molecular and Cellular Mechanisms of Autoimmune Diseases , Institute of Biomedical Research , Affiliate of Vladikavkaz Scientific Center of RAS ;","Junior Researcher , Laboratory of Subcellular Structures , Postgraduate of the Department of Molecular and Cellular Mechanisms of Autoimmune Diseases , Institute of Biomedical Research , Affiliate of Vladikavkaz Scientific Center of RAS ;","\u0418\u043d\u0441\u0442\u0438\u0442\u0443\u0442 \u0431\u0438\u043e\u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0438\u0445 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0439 \u2013 \u0444\u0438\u043b\u0438\u0430\u043b \u0424\u0413\u0411\u0423\u041d \u0424\u0435\u0434\u0435\u0440\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u043d\u0430\u0443\u0447\u043d\u043e\u0433\u043e \u0446\u0435\u043d\u0442\u0440\u0430 \u00ab\u0412\u043b\u0430\u0434\u0438\u043a\u0430\u0432\u043a\u0430\u0437\u0441\u043a\u0438\u0439 \u043d\u0430\u0443\u0447\u043d\u044b\u0439 \u0446\u0435\u043d\u0442\u0440 \u0420\u043e\u0441\u0441\u0438\u0439\u0441\u043a\u043e\u0439 \u0430\u043a\u0430\u0434\u0435\u043c\u0438\u0438 \u043d\u0430\u0443\u043a\u00bb"],"raw_orcid":"https://orcid.org/0000-0002-9154-4729","affiliations":[{"raw_affiliation_string":"Cand. Sci. (Biol.) , Senior Researcher , Laboratory of Subcellular Structures , Department of Molecular and Cellular Mechanisms of Autoimmune Diseases , Institute of Biomedical Research , Affiliate of Vladikavkaz Scientific Center of RAS ;","institution_ids":["https://openalex.org/I4210131691"]},{"raw_affiliation_string":"Junior Researcher , Laboratory of Subcellular Structures , Postgraduate of the Department of Molecular and Cellular Mechanisms of Autoimmune Diseases , Institute of Biomedical Research , Affiliate of Vladikavkaz Scientific Center of RAS ;","institution_ids":["https://openalex.org/I4210131691"]},{"raw_affiliation_string":"\u0418\u043d\u0441\u0442\u0438\u0442\u0443\u0442 \u0431\u0438\u043e\u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0438\u0445 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0439 \u2013 \u0444\u0438\u043b\u0438\u0430\u043b \u0424\u0413\u0411\u0423\u041d \u0424\u0435\u0434\u0435\u0440\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u043d\u0430\u0443\u0447\u043d\u043e\u0433\u043e \u0446\u0435\u043d\u0442\u0440\u0430 \u00ab\u0412\u043b\u0430\u0434\u0438\u043a\u0430\u0432\u043a\u0430\u0437\u0441\u043a\u0438\u0439 \u043d\u0430\u0443\u0447\u043d\u044b\u0439 \u0446\u0435\u043d\u0442\u0440 \u0420\u043e\u0441\u0441\u0438\u0439\u0441\u043a\u043e\u0439 \u0430\u043a\u0430\u0434\u0435\u043c\u0438\u0438 \u043d\u0430\u0443\u043a\u00bb","institution_ids":["https://openalex.org/I4210131691"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"76","last_page":"82"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.4993000030517578,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.4993000030517578,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14072","display_name":"Immunotoxicology and immune responses","score":0.2549000084400177,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.07119999825954437,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tuberculosis","display_name":"tuberculosis","score":0.6510000228881836},{"id":"https://openalex.org/keywords/mycobacterium-tuberculosis","display_name":"Mycobacterium tuberculosis","score":0.9869999885559082},{"id":"https://openalex.org/keywords/autoimmune-disease","display_name":"autoimmune disease","score":0.6169999837875366},{"id":"https://openalex.org/keywords/immunotoxicity","display_name":"immunotoxicity","score":0.8240000009536743},{"id":"https://openalex.org/keywords/cellular-respiration","display_name":"cellular respiration","score":0.7070000171661377},{"id":"https://openalex.org/keywords/oxidative-phosphorylation","display_name":"oxidative phosphorylation","score":0.7649999856948853},{"id":"https://openalex.org/keywords/glycolysis","display_name":"glycolysis","score":0.8889999985694885},{"id":"https://openalex.org/keywords/lactate-dehydrogenase","display_name":"lactate dehydrogenase","score":0.9340000152587891},{"id":"https://openalex.org/keywords/succinate-dehydrogenase","display_name":"succinate dehydrogenase","score":1.0},{"id":"https://openalex.org/keywords/complete-freund-s-adjuvant","display_name":"complete Freund's adjuvant","score":0.8209999799728394},{"id":"https://openalex.org/keywords/rheumatoid-arthritis","display_name":"rheumatoid arthritis","score":0.8360000252723694},{"id":"https://openalex.org/keywords/bone-resorption","display_name":"bone resorption","score":0.9850000143051147},{"id":"https://openalex.org/keywords/erythrocyte-sedimentation-rate","display_name":"erythrocyte sedimentation rate","score":0.9100000262260437},{"id":"https://openalex.org/keywords/wistar-rats","display_name":"Wistar rats","score":0.699999988079071}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7783626914024353},{"id":"https://openalex.org/C2781069245","wikidata":"https://www.wikidata.org/wiki/Q12204","display_name":"Tuberculosis","level":2,"score":0.6671567559242249},{"id":"https://openalex.org/C2777575956","wikidata":"https://www.wikidata.org/wiki/Q187255","display_name":"Rheumatoid arthritis","level":2,"score":0.6354668140411377},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.61709064245224},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.560644268989563},{"id":"https://openalex.org/C2778143017","wikidata":"https://www.wikidata.org/wiki/Q111208","display_name":"Erythrocyte sedimentation rate","level":2,"score":0.5519921183586121},{"id":"https://openalex.org/C2777975735","wikidata":"https://www.wikidata.org/wiki/Q130971","display_name":"Mycobacterium tuberculosis","level":3,"score":0.5225812196731567},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.4880153238773346},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.45479822158813477},{"id":"https://openalex.org/C2777863537","wikidata":"https://www.wikidata.org/wiki/Q357896","display_name":"Adjuvant","level":2,"score":0.4136425256729126},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.37303411960601807},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.1597001850605011}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.35627/2219-5238/2021-29-11-76-82","doi":"https://doi.org/10.35627/2219-5238/2021-29-11-76-82","is_oa":true,"landing_page_url":"https://doi.org/10.35627/2219-5238/2021-29-11-76-82","pdf_url":"https://zniso.fcgie.ru/jour/article/download/728/592","source":{"id":"https://openalex.org/S4210169498","display_name":"\u0417\u0414\u041e\u0420\u041e\u0412\u042c\u0415 \u041d\u0410\u0421\u0415\u041b\u0415\u041d\u0418\u042f \u0418 \u0421\u0420\u0415\u0414\u0410 \u041e\u0411\u0418\u0422\u0410\u041d\u0418\u042f - \u0417\u041d\u0438\u0421\u041e / PUBLIC HEALTH AND LIFE ENVIRONMENT","issn_l":"2219-5238","issn":["2219-5238","2619-0788"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["russia-white-list-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"\u0417\u0414\u041e\u0420\u041e\u0412\u042c\u0415 \u041d\u0410\u0421\u0415\u041b\u0415\u041d\u0418\u042f \u0418 \u0421\u0420\u0415\u0414\u0410 \u041e\u0411\u0418\u0422\u0410\u041d\u0418\u042f - \u0417\u041d\u0438\u0421\u041e / PUBLIC HEALTH AND LIFE ENVIRONMENT","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.35627/2219-5238/2021-29-11-76-82","doi":"https://doi.org/10.35627/2219-5238/2021-29-11-76-82","is_oa":true,"landing_page_url":"https://doi.org/10.35627/2219-5238/2021-29-11-76-82","pdf_url":"https://zniso.fcgie.ru/jour/article/download/728/592","source":{"id":"https://openalex.org/S4210169498","display_name":"\u0417\u0414\u041e\u0420\u041e\u0412\u042c\u0415 \u041d\u0410\u0421\u0415\u041b\u0415\u041d\u0418\u042f \u0418 \u0421\u0420\u0415\u0414\u0410 \u041e\u0411\u0418\u0422\u0410\u041d\u0418\u042f - \u0417\u041d\u0438\u0421\u041e / PUBLIC HEALTH AND LIFE ENVIRONMENT","issn_l":"2219-5238","issn":["2219-5238","2619-0788"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["russia-white-list-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"\u0417\u0414\u041e\u0420\u041e\u0412\u042c\u0415 \u041d\u0410\u0421\u0415\u041b\u0415\u041d\u0418\u042f \u0418 \u0421\u0420\u0415\u0414\u0410 \u041e\u0411\u0418\u0422\u0410\u041d\u0418\u042f - \u0417\u041d\u0438\u0421\u041e / PUBLIC HEALTH AND LIFE ENVIRONMENT","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4200325630.pdf","grobid_xml":"https://content.openalex.org/works/W4200325630.grobid-xml"},"referenced_works_count":15,"referenced_works":["https://openalex.org/W765107315","https://openalex.org/W2013299443","https://openalex.org/W2106781193","https://openalex.org/W2113364226","https://openalex.org/W2137617609","https://openalex.org/W2345713210","https://openalex.org/W2611953884","https://openalex.org/W2774577256","https://openalex.org/W2890138007","https://openalex.org/W2921661072","https://openalex.org/W3014977997","https://openalex.org/W3025489580","https://openalex.org/W3083676524","https://openalex.org/W3089651222","https://openalex.org/W7094442314"],"related_works":["https://openalex.org/W2538644225","https://openalex.org/W2329632880","https://openalex.org/W4282828673","https://openalex.org/W4390966076","https://openalex.org/W4224228951","https://openalex.org/W2034773612","https://openalex.org/W791436902","https://openalex.org/W3201383835","https://openalex.org/W4406337856","https://openalex.org/W2143473033"],"abstract_inverted_index":{"factors,":[0],"and":[1,25,55,68,74,88,180,186,209,229,247,252,257],"inadequate":[2],"hygiene":[3],"practices":[4],"contribute":[5],"to":[6,35,49,126,131,260],"high":[7],"incidence":[8],"of":[9,23,28,39,46,61,72,101,119,143,200,206,215,217,226,242],"tuberculosis":[10,105,219,256],"in":[11,79,196,231,250],"the":[12,26,37,44,70,111,114,117,132,137,141,144,155,163,197,201],"world.":[13],"Effective":[14],"disease":[15,171],"prevention":[16,253],"shall":[17],"be":[18],"based":[19],"on":[20,236],"scientific":[21],"substantiation":[22],"causality":[24],"mechanisms":[27,249],"its":[29],"development.":[30],"Objective:":[31],"The":[32,86,169,213],"study":[33],"aimed":[34],"investigate":[36],"etiopathogenesis":[38],"autoimmune":[40,170],"disorders":[41,195],"associated":[42,221,258],"with":[43,222,244],"exposure":[45],"warm-blooded":[47],"animals":[48,203],"heat":[50,102],"killed":[51],"M.":[52,104,218],"tuberculosis.":[53],"Materials":[54],"methods:":[56],"We":[57],"determined":[58],"hematological":[59],"parameters":[60],"old":[62],"Wistar":[63],"rats":[64],"using":[65,82],"standard":[66],"methods":[67],"estimated":[69],"activity":[71],"lactate":[73],"succinate":[75],"dehydrogenases":[76],"(LDH,":[77],"SDH)":[78],"lymphocytes":[80],"(mitochondria)":[81],"a":[83,149],"cytobiochemical":[84],"method.":[85],"clinical":[87],"laboratory":[89],"results":[90],"were":[91],"confirmed":[92],"by":[93,99,136,154,166,175,183],"X-ray":[94,193],"tests.":[95],"Results:":[96],"Inflammation":[97],"induced":[98],"administration":[100],"inactivated":[103],"(complete":[106],"Freund\u2019s":[107],"adjuvant":[108],"(CFA))":[109],"reached":[110],"maximum":[112],"during":[113],"third":[115],"week:":[116],"number":[118],"white":[120],"blood":[121],"cells":[122,228],"increased":[123,156],"from":[124],"(9.8":[125],"11.3)":[127],"\u00d7":[128],"109/L":[129],"compared":[130],"control":[133],"animals,":[134],"normalizing":[135],"seventh":[138],"week.":[139],"By":[140],"end":[142],"first":[145],"week,":[146],"there":[147],"was":[148,173],"pronounced":[150],"immune":[151,227],"response":[152],"manifested":[153],"erythrocyte":[157],"sedimentation":[158],"rate,":[159],"which":[160],"later":[161],"exceeded":[162],"threshold":[164],"limit":[165],"87\u2013100":[167],"%.":[168],"progression":[172],"accompanied":[174],"impaired":[176,223],"cellular":[177],"respiration":[178],"(glycolysis":[179],"oxidative":[181],"phosphorylation)":[182],"40":[184],"%":[185],"77":[187],"%,":[188],"respectively":[189],"(p":[190],"<":[191],"0.01).":[192],"revealed":[194],"articular":[198],"apparatus":[199],"exposed":[202],"including":[204],"signs":[205],"rheumatoid":[207],"arthritis":[208],"bone":[210],"resorption.":[211],"Conclusion:":[212],"mechanism":[214],"immunotoxicity":[216],"is":[220],"energy":[224],"supply":[225],"changes":[230],"their":[232],"morpho-functional":[233],"properties.":[234],"Based":[235],"our":[237],"findings,":[238],"we":[239],"recommend":[240],"inclusion":[241],"drugs":[243],"immunomodulatory,":[245],"antihypoxic":[246],"osteoprotective":[248],"treatment":[251],"regimens":[254],"for":[255],"diseases":[259],"enhance":[261],"therapeutic":[262],"efficacy.":[263]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2021-12-31T00:00:00"}