{"id":"https://openalex.org/W4200323925","doi":"https://doi.org/10.1039/d1nr05479a","title":"Deep and compact dentinal tubule occlusion via biomimetic mineralization and mineral overgrowth","display_name":"Deep and compact dentinal tubule occlusion via biomimetic mineralization and mineral overgrowth","publication_year":2021,"publication_date":"2021-12-06","ids":{"openalex":"https://openalex.org/W4200323925","doi":"https://doi.org/10.1039/d1nr05479a","pmid":"https://pubmed.ncbi.nlm.nih.gov/34935821"},"language":"en","primary_location":{"id":"doi:10.1039/d1nr05479a","doi":"https://doi.org/10.1039/d1nr05479a","is_oa":false,"landing_page_url":"https://doi.org/10.1039/d1nr05479a","pdf_url":null,"source":{"id":"https://openalex.org/S23181512","display_name":"Nanoscale","issn_l":"2040-3364","issn":["2040-3364","2040-3372"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanoscale","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100345057","display_name":"Zhuo Chen","orcid":"https://orcid.org/0000-0001-8247-7387","observed_orcids":["https://orcid.org/0000-0001-8247-7387","https://orcid.org/0009-0007-9380-732X"]},"institutions":[{"id":"https://openalex.org/I37461747","display_name":"Wuhan University","ror":"https://ror.org/033vjfk17","country_code":"CN","type":"education","lineage":["https://openalex.org/I37461747"]},{"id":"https://openalex.org/I4210121744","display_name":"Zhejiang University Medical College Affiliated Stomatological Hospital","ror":"https://ror.org/02yk7ya44","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210121744"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhuo Chen","raw_affiliation_strings":["Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral Diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China","The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan 430072, China"],"raw_orcid":"https://orcid.org/0000-0001-8247-7387","affiliations":[{"raw_affiliation_string":"Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral Diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China","institution_ids":["https://openalex.org/I4210121744","https://openalex.org/I76130692"]},{"raw_affiliation_string":"The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan 430072, China","institution_ids":["https://openalex.org/I37461747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024693751","display_name":"Yuyan Duan","orcid":"https://orcid.org/0000-0002-4045-2541","observed_orcids":["https://orcid.org/0000-0002-4045-2541"]},"institutions":[{"id":"https://openalex.org/I4210121744","display_name":"Zhejiang University Medical College Affiliated Stomatological Hospital","ror":"https://ror.org/02yk7ya44","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210121744"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuyan Duan","raw_affiliation_strings":["Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral Diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China"],"raw_orcid":"https://orcid.org/0000-0002-4045-2541","affiliations":[{"raw_affiliation_string":"Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral Diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China","institution_ids":["https://openalex.org/I4210121744","https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013183925","display_name":"Songzhe Shan","orcid":"https://orcid.org/0000-0003-1477-9476","observed_orcids":["https://orcid.org/0000-0003-1477-9476"]},"institutions":[{"id":"https://openalex.org/I4210121744","display_name":"Zhejiang University Medical College Affiliated Stomatological Hospital","ror":"https://ror.org/02yk7ya44","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210121744"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Songzhe Shan","raw_affiliation_strings":["Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral Diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China"],"raw_orcid":"https://orcid.org/0000-0003-1477-9476","affiliations":[{"raw_affiliation_string":"Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral Diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China","institution_ids":["https://openalex.org/I4210121744","https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067188767","display_name":"Kaida Sun","orcid":"https://orcid.org/0000-0001-9152-5141","observed_orcids":["https://orcid.org/0000-0001-9152-5141"]},"institutions":[{"id":"https://openalex.org/I4210121744","display_name":"Zhejiang University Medical College Affiliated Stomatological Hospital","ror":"https://ror.org/02yk7ya44","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210121744"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kaida Sun","raw_affiliation_strings":["Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral Diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China"],"raw_orcid":"https://orcid.org/0000-0001-9152-5141","affiliations":[{"raw_affiliation_string":"Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral Diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China","institution_ids":["https://openalex.org/I4210121744","https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101541103","display_name":"Gang Wang","orcid":"https://orcid.org/0000-0002-6444-1484","observed_orcids":["https://orcid.org/0000-0002-6444-1484"]},"institutions":[{"id":"https://openalex.org/I4210121744","display_name":"Zhejiang University Medical College Affiliated Stomatological Hospital","ror":"https://ror.org/02yk7ya44","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210121744"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Gang Wang","raw_affiliation_strings":["Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral Diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China"],"raw_orcid":"https://orcid.org/0000-0002-6444-1484","affiliations":[{"raw_affiliation_string":"Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral Diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China","institution_ids":["https://openalex.org/I4210121744","https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018193784","display_name":"Changyu Shao","orcid":"https://orcid.org/0000-0001-8191-0871","observed_orcids":["https://orcid.org/0000-0001-8191-0871"]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Changyu Shao","raw_affiliation_strings":["Center for Biomaterials and Biopathways, Department of Chemistry, Zhejiang University, Hangzhou 310027, China"],"raw_orcid":"https://orcid.org/0000-0001-8191-0871","affiliations":[{"raw_affiliation_string":"Center for Biomaterials and Biopathways, Department of Chemistry, Zhejiang University, Hangzhou 310027, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037630891","display_name":"Zhenhang Tang","orcid":"https://orcid.org/0000-0002-7312-4296","observed_orcids":["https://orcid.org/0000-0002-7312-4296"]},"institutions":[{"id":"https://openalex.org/I4210121744","display_name":"Zhejiang University Medical College Affiliated Stomatological Hospital","ror":"https://ror.org/02yk7ya44","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210121744"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhenhang Tang","raw_affiliation_strings":["Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral Diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China"],"raw_orcid":"https://orcid.org/0000-0002-7312-4296","affiliations":[{"raw_affiliation_string":"Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral Diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China","institution_ids":["https://openalex.org/I4210121744","https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Zekai Xu","orcid":"https://orcid.org/0000-0002-8462-574X","observed_orcids":["https://orcid.org/0000-0002-8462-574X"]},"institutions":[{"id":"https://openalex.org/I4210121744","display_name":"Zhejiang University Medical College Affiliated Stomatological Hospital","ror":"https://ror.org/02yk7ya44","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210121744"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zekai Xu","raw_affiliation_strings":["Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral Diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China"],"raw_orcid":"https://orcid.org/0000-0002-8462-574X","affiliations":[{"raw_affiliation_string":"Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral Diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China","institution_ids":["https://openalex.org/I4210121744","https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066415299","display_name":"Yanyan Zhou","orcid":"https://orcid.org/0000-0001-5460-8917","observed_orcids":["https://orcid.org/0000-0001-5460-8917","https://orcid.org/0000-0002-8813-3777"]},"institutions":[{"id":"https://openalex.org/I4210121744","display_name":"Zhejiang University Medical College Affiliated Stomatological Hospital","ror":"https://ror.org/02yk7ya44","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210121744"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yanyan Zhou","raw_affiliation_strings":["Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral Diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China"],"raw_orcid":"https://orcid.org/0000-0001-5460-8917","affiliations":[{"raw_affiliation_string":"Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral Diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China","institution_ids":["https://openalex.org/I4210121744","https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028166621","display_name":"Zhi Chen","orcid":"https://orcid.org/0000-0003-2095-1324","observed_orcids":["https://orcid.org/0000-0003-2095-1324"]},"institutions":[{"id":"https://openalex.org/I37461747","display_name":"Wuhan University","ror":"https://ror.org/033vjfk17","country_code":"CN","type":"education","lineage":["https://openalex.org/I37461747"]},{"id":"https://openalex.org/I4210121744","display_name":"Zhejiang University Medical College Affiliated Stomatological Hospital","ror":"https://ror.org/02yk7ya44","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210121744"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhi Chen","raw_affiliation_strings":["Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral Diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China","The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan 430072, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral Diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China","institution_ids":["https://openalex.org/I4210121744","https://openalex.org/I76130692"]},{"raw_affiliation_string":"The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan 430072, China","institution_ids":["https://openalex.org/I37461747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049073234","display_name":"Ruikang Tang","orcid":"https://orcid.org/0000-0001-5277-7338","observed_orcids":["https://orcid.org/0000-0001-5277-7338","https://orcid.org/0000-0003-2933-7582"]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ruikang Tang","raw_affiliation_strings":["Center for Biomaterials and Biopathways, Department of Chemistry, Zhejiang University, Hangzhou 310027, China"],"raw_orcid":"https://orcid.org/0000-0001-5277-7338","affiliations":[{"raw_affiliation_string":"Center for Biomaterials and Biopathways, Department of Chemistry, Zhejiang University, Hangzhou 310027, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081887189","display_name":"Haihua Pan","orcid":"https://orcid.org/0000-0003-0327-7622","observed_orcids":["https://orcid.org/0000-0003-0327-7622"]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Haihua Pan","raw_affiliation_strings":["Qiushi Academy for Advanced Studies, Zhejiang University, Hangzhou 310027, China"],"raw_orcid":"https://orcid.org/0000-0003-0327-7622","affiliations":[{"raw_affiliation_string":"Qiushi Academy for Advanced Studies, Zhejiang University, Hangzhou 310027, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007708880","display_name":"Zhijian Xie","orcid":"https://orcid.org/0000-0003-0122-0948","observed_orcids":["https://orcid.org/0000-0003-0122-0948"]},"institutions":[{"id":"https://openalex.org/I4210121744","display_name":"Zhejiang University Medical College Affiliated Stomatological Hospital","ror":"https://ror.org/02yk7ya44","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210121744"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zhijian Xie","raw_affiliation_strings":["Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral Diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China"],"raw_orcid":"https://orcid.org/0000-0003-0122-0948","affiliations":[{"raw_affiliation_string":"Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral Diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China","institution_ids":["https://openalex.org/I4210121744","https://openalex.org/I76130692"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5007708880","https://openalex.org/A5081887189"],"corresponding_institution_ids":["https://openalex.org/I4210121744","https://openalex.org/I76130692"],"apc_list":null,"apc_paid":null,"fwci":5.3873,"has_fulltext":false,"cited_by_count":37,"citation_normalized_percentile":{"value":0.965508,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"14","issue":"3","first_page":"642","last_page":"652"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11958","display_name":"Dental Erosion and Treatment","score":0.9595000147819519,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11958","display_name":"Dental Erosion and Treatment","score":0.9595000147819519,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10536","display_name":"Endodontics and Root Canal Treatments","score":0.009800000116229057,"subfield":{"id":"https://openalex.org/subfields/3504","display_name":"Oral Surgery"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11278","display_name":"Calcium Carbonate Crystallization and Inhibition","score":0.006899999920278788,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dentinal-tubule-occlusion","display_name":"dentinal tubule occlusion","score":0.9990000128746033},{"id":"https://openalex.org/keywords/dentin-hypersensitivity","display_name":"dentin hypersensitivity","score":0.9679999947547913},{"id":"https://openalex.org/keywords/desensitizing-agents","display_name":"desensitizing agents","score":0.9319999814033508},{"id":"https://openalex.org/keywords/biomimetic-mineralization","display_name":"biomimetic mineralization","score":0.9990000128746033},{"id":"https://openalex.org/keywords/acid-tolerance","display_name":"acid resistance","score":0.621999979019165},{"id":"https://openalex.org/keywords/mechanical-resistance","display_name":"mechanical resistance","score":0.6399999856948853},{"id":"https://openalex.org/keywords/dentin","display_name":"dentin","score":0.4699999988079071}],"concepts":[{"id":"https://openalex.org/C2910267089","wikidata":"https://www.wikidata.org/wiki/Q1189904","display_name":"Dentinal Tubule","level":3,"score":0.9306945204734802},{"id":"https://openalex.org/C2776268601","wikidata":"https://www.wikidata.org/wiki/Q968808","display_name":"Occlusion","level":2,"score":0.6347352862358093},{"id":"https://openalex.org/C2780498532","wikidata":"https://www.wikidata.org/wiki/Q7850941","display_name":"Tubule","level":3,"score":0.6289265751838684},{"id":"https://openalex.org/C111696902","wikidata":"https://www.wikidata.org/wiki/Q6864413","display_name":"Mineralization (soil science)","level":3,"score":0.6106990575790405},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5235300064086914},{"id":"https://openalex.org/C2779263046","wikidata":"https://www.wikidata.org/wiki/Q189637","display_name":"Dentin","level":2,"score":0.48668867349624634},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.4478422999382019},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.4033997654914856},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.3857171833515167},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.36712777614593506},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.2322484254837036},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.13290444016456604},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.11699619889259338},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09127461910247803},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.08367663621902466},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.08311998844146729},{"id":"https://openalex.org/C537208039","wikidata":"https://www.wikidata.org/wiki/Q627","display_name":"Nitrogen","level":2,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D003804","descriptor_name":"Dentin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008855","descriptor_name":"Microscopy, Electron, Scanning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008903","descriptor_name":"Minerals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D032701","descriptor_name":"Biomimetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1039/d1nr05479a","doi":"https://doi.org/10.1039/d1nr05479a","is_oa":false,"landing_page_url":"https://doi.org/10.1039/d1nr05479a","pdf_url":null,"source":{"id":"https://openalex.org/S23181512","display_name":"Nanoscale","issn_l":"2040-3364","issn":["2040-3364","2040-3372"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanoscale","raw_type":"journal-article"},{"id":"pmid:34935821","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34935821","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanoscale","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.7246000170707703}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1024923842","display_name":null,"funder_award_id":"2016QN81020","funder_id":"https://openalex.org/F4320329878","funder_display_name":"Central University Basic Research Fund of China"},{"id":"https://openalex.org/G2736107960","display_name":null,"funder_award_id":"21625105","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3522195620","display_name":null,"funder_award_id":"2018YFC1105100","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G3648918035","display_name":null,"funder_award_id":"22077114","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4258438461","display_name":"\u80f6\u539f\u7ea4\u7ef4\u77ff\u5316\u7ed3\u6676\u52a8\u529b\u5b66\u65b9\u6cd5\u7684\u6784\u5efa\u4e0e\u8c03\u63a7\u673a\u5236\u7814\u7a76","funder_award_id":"21771160","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7220417806","display_name":null,"funder_award_id":"81771118","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320329878","display_name":"Central University Basic Research Fund of China","ror":null},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W1988276020","https://openalex.org/W1994714258","https://openalex.org/W2003164113","https://openalex.org/W2004259045","https://openalex.org/W2008271519","https://openalex.org/W2011215233","https://openalex.org/W2024313867","https://openalex.org/W2028184464","https://openalex.org/W2035982352","https://openalex.org/W2041092917","https://openalex.org/W2042099613","https://openalex.org/W2043314765","https://openalex.org/W2044602169","https://openalex.org/W2072879492","https://openalex.org/W2094794720","https://openalex.org/W2117119839","https://openalex.org/W2121769407","https://openalex.org/W2127000141","https://openalex.org/W2136116635","https://openalex.org/W2140524010","https://openalex.org/W2142529660","https://openalex.org/W2144551409","https://openalex.org/W2146244968","https://openalex.org/W2156436127","https://openalex.org/W2160025986","https://openalex.org/W2223438109","https://openalex.org/W2506454372","https://openalex.org/W2549649012","https://openalex.org/W2573472493","https://openalex.org/W2593611787","https://openalex.org/W2605298439","https://openalex.org/W2766790142","https://openalex.org/W2783627539","https://openalex.org/W2791353032","https://openalex.org/W2795745522","https://openalex.org/W2809359310","https://openalex.org/W2946942886","https://openalex.org/W2969272360","https://openalex.org/W2976711111","https://openalex.org/W2980766103","https://openalex.org/W3005279601","https://openalex.org/W3125384829"],"related_works":["https://openalex.org/W7164737687","https://openalex.org/W7171513051","https://openalex.org/W4415831302","https://openalex.org/W4407590618","https://openalex.org/W4407808722","https://openalex.org/W4388095037","https://openalex.org/W4410247052","https://openalex.org/W3091811549","https://openalex.org/W3193881144","https://openalex.org/W2008271519"],"abstract_inverted_index":{"Dentinal":[0],"tubule":[1,90],"(DT)":[2],"occlusion":[3,38,94],"by":[4],"desensitizing":[5,25],"agents":[6,26],"has":[7],"been":[8],"widely":[9],"applied":[10],"to":[11,65,85],"inhibit":[12],"the":[13,32,60,71,86,105],"transmission":[14],"of":[15,34,44,59,73,107],"external":[16],"stimuli":[17],"that":[18,81],"cause":[19],"dentin":[20],"hypersensitivity":[21],"(DH).":[22],"However,":[23],"most":[24],"merely":[27],"accomplish":[28],"porous":[29],"blocking":[30],"or":[31],"formation":[33,72],"a":[35,42,74],"superficial":[36],"tubular":[37],"layer,":[39],"resulting":[40,69],"in":[41,70],"lack":[43],"mechanical":[45,99],"and":[46,49,56,76,101,111],"acid":[47,102],"resistance":[48,100],"long-term":[50],"stability.":[51],"Herein,":[52],"combining":[53],"biomimetic":[54],"mineralization":[55],"mineral":[57,79],"overgrowth":[58],"dentinal":[61],"matrix":[62,88],"was":[63],"shown":[64],"effectively":[66],"occlude":[67],"DTs,":[68],"compact":[75],"deep":[77],"occluding":[78],"layer":[80],"is":[82],"strongly":[83],"bound":[84],"organic":[87],"on":[89],"walls.":[91],"This":[92],"DT":[93],"method":[95],"could":[96],"achieve":[97],"both":[98],"resistance,":[103],"demonstrating":[104],"potential":[106],"an":[108],"inexpensive,":[109],"long-term,":[110],"efficient":[112],"therapy":[113],"for":[114],"treating":[115],"DH.":[116]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":14},{"year":2022,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2021-12-31T00:00:00"}