{"id":"https://openalex.org/W4200317620","doi":"https://doi.org/10.15324/kjcls.2021.53.4.285","title":"Obesity, Obstructive Sleep Apnea, and Metabolic Dysfunction","display_name":"Obesity, Obstructive Sleep Apnea, and Metabolic Dysfunction","publication_year":2021,"publication_date":"2021-12-21","ids":{"openalex":"https://openalex.org/W4200317620","doi":"https://doi.org/10.15324/kjcls.2021.53.4.285"},"language":"en","primary_location":{"id":"doi:10.15324/kjcls.2021.53.4.285","doi":"https://doi.org/10.15324/kjcls.2021.53.4.285","is_oa":true,"landing_page_url":"https://doi.org/10.15324/kjcls.2021.53.4.285","pdf_url":"http://www.kjcls.org/journal/download_pdf.php?doi=10.15324/kjcls.2021.53.4.285","source":{"id":"https://openalex.org/S4210214161","display_name":"Korean Journal of Clinical Laboratory Science","issn_l":"1738-3544","issn":["1738-3544","2288-1662"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","kci-registered"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Korean Journal of Clinical Laboratory Science","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"http://www.kjcls.org/journal/download_pdf.php?doi=10.15324/kjcls.2021.53.4.285","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5059545992","display_name":"Jinkwan Kim","orcid":"https://orcid.org/0000-0002-7123-1354","observed_orcids":["https://orcid.org/0000-0002-7123-1354"]},"institutions":[{"id":"https://openalex.org/I4210149646","display_name":"Jungwon University","ror":"https://ror.org/050mgpz97","country_code":"KR","type":"education","lineage":["https://openalex.org/I4210149646"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jinkwan Kim","raw_affiliation_strings":["Department of Biomedical Laboratory Science, Jungwon University, Goesan, Korea","Sleep Medicine Institute, Jungwon University, Goesan, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Laboratory Science, Jungwon University, Goesan, Korea","institution_ids":["https://openalex.org/I4210149646"]},{"raw_affiliation_string":"Sleep Medicine Institute, Jungwon University, Goesan, Korea","institution_ids":["https://openalex.org/I4210149646"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014480689","display_name":"Sang Shin Pyo","orcid":"https://orcid.org/0000-0003-3043-0178","observed_orcids":["https://orcid.org/0000-0003-3043-0178"]},"institutions":[{"id":"https://openalex.org/I4210149646","display_name":"Jungwon University","ror":"https://ror.org/050mgpz97","country_code":"KR","type":"education","lineage":["https://openalex.org/I4210149646"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Sang Shin Pyo","raw_affiliation_strings":["Department of Biomedical Laboratory Science, Jungwon University, Goesan, Korea","Sleep Medicine Institute, Jungwon University, Goesan, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Laboratory Science, Jungwon University, Goesan, Korea","institution_ids":["https://openalex.org/I4210149646"]},{"raw_affiliation_string":"Sleep Medicine Institute, Jungwon University, Goesan, Korea","institution_ids":["https://openalex.org/I4210149646"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5069644902","display_name":"Dae Wui Yoon","orcid":"https://orcid.org/0000-0001-8875-2255","observed_orcids":["https://orcid.org/0000-0001-8875-2255"]},"institutions":[{"id":"https://openalex.org/I4210149646","display_name":"Jungwon University","ror":"https://ror.org/050mgpz97","country_code":"KR","type":"education","lineage":["https://openalex.org/I4210149646"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Dae Wui Yoon","raw_affiliation_strings":["Department of Biomedical Laboratory Science, Jungwon University, Goesan, Korea","Sleep Medicine Institute, Jungwon University, Goesan, Korea"],"raw_orcid":"https://orcid.org/0000-0001-8875-2255","affiliations":[{"raw_affiliation_string":"Department of Biomedical Laboratory Science, Jungwon University, Goesan, Korea","institution_ids":["https://openalex.org/I4210149646"]},{"raw_affiliation_string":"Sleep Medicine Institute, Jungwon University, Goesan, Korea","institution_ids":["https://openalex.org/I4210149646"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5069644902"],"corresponding_institution_ids":["https://openalex.org/I4210149646"],"apc_list":null,"apc_paid":null,"fwci":0.1523,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.38743831,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"53","issue":"4","first_page":"285","last_page":"295"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10316","display_name":"Sleep and related disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/obstructive-sleep-apnea","display_name":"obstructive sleep apnea","score":0.9919999837875366},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":1.0},{"id":"https://openalex.org/keywords/metabolic-dysfunction","display_name":"metabolic dysfunction","score":0.9890000224113464},{"id":"https://openalex.org/keywords/metabolic-disorders","display_name":"metabolic disorders","score":0.7269999980926514},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.8709999918937683},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":1.0},{"id":"https://openalex.org/keywords/appetite-hormones","display_name":"appetite-regulating hormones","score":0.996999979019165},{"id":"https://openalex.org/keywords/pathophysiological-mechanisms","display_name":"pathophysiological mechanisms","score":0.8009999990463257}],"concepts":[{"id":"https://openalex.org/C2776006263","wikidata":"https://www.wikidata.org/wiki/Q16606552","display_name":"Obstructive sleep apnea","level":2,"score":0.8084474802017212},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.743664026260376},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6274486184120178},{"id":"https://openalex.org/C2777935920","wikidata":"https://www.wikidata.org/wiki/Q213600","display_name":"Sleep apnea","level":2,"score":0.5569990277290344},{"id":"https://openalex.org/C2775841894","wikidata":"https://www.wikidata.org/wiki/Q4683692","display_name":"Sleep (system call)","level":2,"score":0.519059956073761},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4097636342048645},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.38643351197242737},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.09501507878303528},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.15324/kjcls.2021.53.4.285","doi":"https://doi.org/10.15324/kjcls.2021.53.4.285","is_oa":true,"landing_page_url":"https://doi.org/10.15324/kjcls.2021.53.4.285","pdf_url":"http://www.kjcls.org/journal/download_pdf.php?doi=10.15324/kjcls.2021.53.4.285","source":{"id":"https://openalex.org/S4210214161","display_name":"Korean Journal of Clinical Laboratory Science","issn_l":"1738-3544","issn":["1738-3544","2288-1662"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","kci-registered"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Korean Journal of Clinical Laboratory Science","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:7100ff0f51074bf199c393b16ce9eb83","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/7100ff0f51074bf199c393b16ce9eb83","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Korean Journal of Clinical Laboratory Science, Vol 53, Iss 4, Pp 285-295 (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.15324/kjcls.2021.53.4.285","doi":"https://doi.org/10.15324/kjcls.2021.53.4.285","is_oa":true,"landing_page_url":"https://doi.org/10.15324/kjcls.2021.53.4.285","pdf_url":"http://www.kjcls.org/journal/download_pdf.php?doi=10.15324/kjcls.2021.53.4.285","source":{"id":"https://openalex.org/S4210214161","display_name":"Korean Journal of Clinical Laboratory Science","issn_l":"1738-3544","issn":["1738-3544","2288-1662"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","kci-registered"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Korean Journal of Clinical Laboratory Science","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321246","display_name":"Jungwon University","ror":"https://ror.org/050mgpz97"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4200317620.pdf","grobid_xml":"https://content.openalex.org/works/W4200317620.grobid-xml"},"referenced_works_count":89,"referenced_works":["https://openalex.org/W99276571","https://openalex.org/W200710200","https://openalex.org/W1555389818","https://openalex.org/W1559525331","https://openalex.org/W1575558149","https://openalex.org/W1673125506","https://openalex.org/W1858730046","https://openalex.org/W1894345071","https://openalex.org/W1963855767","https://openalex.org/W1964776680","https://openalex.org/W1968071340","https://openalex.org/W1970596096","https://openalex.org/W1971452427","https://openalex.org/W1971926198","https://openalex.org/W1975319022","https://openalex.org/W1975324052","https://openalex.org/W1977068381","https://openalex.org/W1977325333","https://openalex.org/W1981338699","https://openalex.org/W1997188928","https://openalex.org/W1997678064","https://openalex.org/W1999346088","https://openalex.org/W2010957046","https://openalex.org/W2013252791","https://openalex.org/W2013890897","https://openalex.org/W2021270449","https://openalex.org/W2021840875","https://openalex.org/W2024431022","https://openalex.org/W2030390156","https://openalex.org/W2030450361","https://openalex.org/W2031750226","https://openalex.org/W2036843052","https://openalex.org/W2041510403","https://openalex.org/W2045058491","https://openalex.org/W2047257800","https://openalex.org/W2048238870","https://openalex.org/W2052897592","https://openalex.org/W2054593321","https://openalex.org/W2057023498","https://openalex.org/W2058610272","https://openalex.org/W2060823593","https://openalex.org/W2063135200","https://openalex.org/W2065180033","https://openalex.org/W2067338371","https://openalex.org/W2067906965","https://openalex.org/W2068527329","https://openalex.org/W2077022391","https://openalex.org/W2082533403","https://openalex.org/W2085680012","https://openalex.org/W2085750411","https://openalex.org/W2087486791","https://openalex.org/W2088456053","https://openalex.org/W2088940658","https://openalex.org/W2089272122","https://openalex.org/W2089789513","https://openalex.org/W2092509345","https://openalex.org/W2105727933","https://openalex.org/W2106890887","https://openalex.org/W2109650317","https://openalex.org/W2117722030","https://openalex.org/W2118490190","https://openalex.org/W2120071870","https://openalex.org/W2120443496","https://openalex.org/W2120824707","https://openalex.org/W2122829469","https://openalex.org/W2127939248","https://openalex.org/W2130766522","https://openalex.org/W2145317285","https://openalex.org/W2145583804","https://openalex.org/W2147847833","https://openalex.org/W2151624371","https://openalex.org/W2152726111","https://openalex.org/W2157118250","https://openalex.org/W2157655916","https://openalex.org/W2162650381","https://openalex.org/W2162945592","https://openalex.org/W2166487029","https://openalex.org/W2171380458","https://openalex.org/W2264784497","https://openalex.org/W2336788764","https://openalex.org/W2483520518","https://openalex.org/W2557901763","https://openalex.org/W2605720581","https://openalex.org/W2893673243","https://openalex.org/W2895076876","https://openalex.org/W2937700756","https://openalex.org/W2949409658","https://openalex.org/W4245956859","https://openalex.org/W4256475235"],"related_works":["https://openalex.org/W2285684434","https://openalex.org/W1480885089","https://openalex.org/W2803284766","https://openalex.org/W4392760753","https://openalex.org/W1972056446","https://openalex.org/W2120719619","https://openalex.org/W2116522368","https://openalex.org/W2886874140","https://openalex.org/W16421494","https://openalex.org/W2583934085"],"abstract_inverted_index":{"Sleep":[0],"plays":[1],"an":[2,75],"important":[3,115],"role":[4],"in":[5,32,49,124],"maintaining":[6],"overall":[7],"human":[8],"health.There":[9],"is":[10,26,60,68],"increasing":[11,39],"interest":[12],"regarding":[13,136],"the":[14,33,36,50,61,81,99,107,131,137,145,162],"impact":[15],"of":[16,38,52,101,109,118,134,139,161],"sleep":[17,23],"related":[18],"disorders":[19],"on":[20],"metabolic":[21,58,87,119,142,173],"diseases.Obstructive":[22],"apnea":[24],"(OSA)":[25],"a":[27,46],"common":[28],"health":[29],"problem,":[30],"and":[31,79,92,103,106,121,144,167,169,172],"last":[34],"decade,":[35],"emergence":[37],"obesity":[40,122,168],"rates":[41],"has":[42],"further":[43],"led":[44],"to":[45,71,85,95,154],"remarkable":[47],"increase":[48],"prevalence":[51],"OSA,":[53],"along":[54],"with":[55,126,141],"more":[56],"prominent":[57],"diseases.Obesity":[59],"strongest":[62],"risk":[63],"factor":[64],"for":[65],"OSA.However,":[66],"OSA":[67,78,140,151,166,171],"also":[69],"known":[70],"cause":[72],"obesity,":[73],"suggesting":[74],"interaction":[76],"between":[77,165,170],"obesity.Although":[80],"underlying":[82],"mechanisms":[83,148],"leading":[84],"OSA-induced":[86],"diseases":[88,143],"are":[89,93],"probably":[90],"multi-factorial":[91],"yet":[94],"be":[96],"fully":[97],"elucidated,":[98],"activation":[100],"inflammation":[102],"oxidative":[104],"stress":[105],"dysregulation":[108],"appetite-regulating":[110],"hormones":[111],"have":[112],"emerged":[113],"as":[114],"pathophysiological":[116,147],"components":[117],"dysfunction":[120],"observed":[123],"patients":[125],"OSA.Here,":[127],"we":[128],"will":[129,157],"review":[130],"current":[132],"state":[133],"research":[135],"association":[138],"possible":[146],"by":[149],"which":[150],"could":[152],"lead":[153],"such":[155],"diseases.This":[156],"enhance":[158],"our":[159],"understanding":[160],"potential":[163],"interactions":[164],"dysfunction.":[174]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2022,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2021-12-31T00:00:00"}