{"id":"https://openalex.org/W4200243233","doi":"https://doi.org/10.1371/journal.pone.0261401","title":"Computed tomography radiomics for the prediction of thymic epithelial tumor histology, TNM stage and myasthenia gravis","display_name":"Computed tomography radiomics for the prediction of thymic epithelial tumor histology, TNM stage and myasthenia gravis","publication_year":2021,"publication_date":"2021-12-20","ids":{"openalex":"https://openalex.org/W4200243233","doi":"https://doi.org/10.1371/journal.pone.0261401","pmid":"https://pubmed.ncbi.nlm.nih.gov/34928978","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8687592"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pone.0261401","doi":"https://doi.org/10.1371/journal.pone.0261401","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0261401","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0261401&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0261401&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089676369","display_name":"Christian Bl\u00fcthgen","orcid":"https://orcid.org/0000-0001-7321-5676","observed_orcids":["https://orcid.org/0000-0001-7321-5676"]},"institutions":[{"id":"https://openalex.org/I4210100468","display_name":"University Hospital Zurich","ror":"https://ror.org/01462r250","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210100468"]}],"countries":["CH"],"is_corresponding":true,"raw_author_name":"Christian Bl\u00fcthgen","raw_affiliation_strings":["Institute of Diagnostic and Interventional Radiology, University Hospital of Zurich, Zurich, Switzerland"],"raw_orcid":"https://orcid.org/0000-0001-7321-5676","affiliations":[{"raw_affiliation_string":"Institute of Diagnostic and Interventional Radiology, University Hospital of Zurich, Zurich, Switzerland","institution_ids":["https://openalex.org/I4210100468"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080970393","display_name":"Miriam Patella","orcid":"https://orcid.org/0000-0002-7622-9472","observed_orcids":["https://orcid.org/0000-0002-7622-9472"]},"institutions":[{"id":"https://openalex.org/I4210100468","display_name":"University Hospital Zurich","ror":"https://ror.org/01462r250","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210100468"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Miriam Patella","raw_affiliation_strings":["Department of Thoracic Surgery, University Hospital of Zurich, Zurich, Switzerland"],"raw_orcid":"https://orcid.org/0000-0002-7622-9472","affiliations":[{"raw_affiliation_string":"Department of Thoracic Surgery, University Hospital of Zurich, Zurich, Switzerland","institution_ids":["https://openalex.org/I4210100468"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044115261","display_name":"Andr\u00e9 Euler","orcid":"https://orcid.org/0000-0001-5019-4585","observed_orcids":["https://orcid.org/0000-0001-5019-4585"]},"institutions":[{"id":"https://openalex.org/I4210100468","display_name":"University Hospital Zurich","ror":"https://ror.org/01462r250","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210100468"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Andr\u00e9 Euler","raw_affiliation_strings":["Institute of Diagnostic and Interventional Radiology, University Hospital of Zurich, Zurich, Switzerland"],"raw_orcid":"https://orcid.org/0000-0001-5019-4585","affiliations":[{"raw_affiliation_string":"Institute of Diagnostic and Interventional Radiology, University Hospital of Zurich, Zurich, Switzerland","institution_ids":["https://openalex.org/I4210100468"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003254879","display_name":"Bettina Bae\u00dfler","orcid":"https://orcid.org/0000-0002-3244-3864","observed_orcids":["https://orcid.org/0000-0002-3244-3864"]},"institutions":[{"id":"https://openalex.org/I4210100468","display_name":"University Hospital Zurich","ror":"https://ror.org/01462r250","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210100468"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Bettina Baessler","raw_affiliation_strings":["Institute of Diagnostic and Interventional Radiology, University Hospital of Zurich, Zurich, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Diagnostic and Interventional Radiology, University Hospital of Zurich, Zurich, Switzerland","institution_ids":["https://openalex.org/I4210100468"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013754024","display_name":"Katharina Martini","orcid":"https://orcid.org/0000-0002-2638-6832","observed_orcids":["https://orcid.org/0000-0002-2638-6832"]},"institutions":[{"id":"https://openalex.org/I4210100468","display_name":"University Hospital Zurich","ror":"https://ror.org/01462r250","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210100468"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Katharina Martini","raw_affiliation_strings":["Institute of Diagnostic and Interventional Radiology, University Hospital of Zurich, Zurich, Switzerland"],"raw_orcid":"https://orcid.org/0000-0002-2638-6832","affiliations":[{"raw_affiliation_string":"Institute of Diagnostic and Interventional Radiology, University Hospital of Zurich, Zurich, Switzerland","institution_ids":["https://openalex.org/I4210100468"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075835655","display_name":"Jochen von Spiczak","orcid":"https://orcid.org/0000-0002-1978-1535","observed_orcids":["https://orcid.org/0000-0002-1978-1535"]},"institutions":[{"id":"https://openalex.org/I4210100468","display_name":"University Hospital Zurich","ror":"https://ror.org/01462r250","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210100468"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Jochen von Spiczak","raw_affiliation_strings":["Institute of Diagnostic and Interventional Radiology, University Hospital of Zurich, Zurich, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Diagnostic and Interventional Radiology, University Hospital of Zurich, Zurich, Switzerland","institution_ids":["https://openalex.org/I4210100468"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057927894","display_name":"Didier Schneiter","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210100468","display_name":"University Hospital Zurich","ror":"https://ror.org/01462r250","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210100468"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Didier Schneiter","raw_affiliation_strings":["Department of Thoracic Surgery, University Hospital of Zurich, Zurich, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Thoracic Surgery, University Hospital of Zurich, Zurich, Switzerland","institution_ids":["https://openalex.org/I4210100468"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087464605","display_name":"Isabelle Opitz","orcid":"https://orcid.org/0000-0001-5900-9040","observed_orcids":["https://orcid.org/0000-0001-5900-9040"]},"institutions":[{"id":"https://openalex.org/I4210100468","display_name":"University Hospital Zurich","ror":"https://ror.org/01462r250","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210100468"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Isabelle Opitz","raw_affiliation_strings":["Department of Thoracic Surgery, University Hospital of Zurich, Zurich, Switzerland"],"raw_orcid":"https://orcid.org/0000-0001-5900-9040","affiliations":[{"raw_affiliation_string":"Department of Thoracic Surgery, University Hospital of Zurich, Zurich, Switzerland","institution_ids":["https://openalex.org/I4210100468"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031002175","display_name":"Thomas Frauenfelder","orcid":"https://orcid.org/0000-0002-3295-6619","observed_orcids":["https://orcid.org/0000-0002-3295-6619"]},"institutions":[{"id":"https://openalex.org/I4210100468","display_name":"University Hospital Zurich","ror":"https://ror.org/01462r250","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210100468"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Thomas Frauenfelder","raw_affiliation_strings":["Institute of Diagnostic and Interventional Radiology, University Hospital of Zurich, Zurich, Switzerland"],"raw_orcid":"https://orcid.org/0000-0002-3295-6619","affiliations":[{"raw_affiliation_string":"Institute of Diagnostic and Interventional Radiology, University Hospital of Zurich, Zurich, Switzerland","institution_ids":["https://openalex.org/I4210100468"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5089676369"],"corresponding_institution_ids":["https://openalex.org/I4210100468"],"apc_list":{"value":1749,"currency":"USD","value_usd":1749},"apc_paid":{"value":1749,"currency":"USD","value_usd":1749},"fwci":2.2861,"has_fulltext":true,"cited_by_count":38,"citation_normalized_percentile":{"value":0.89295159,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"16","issue":"12","first_page":"e0261401","last_page":"e0261401"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11271","display_name":"Myasthenia Gravis and Thymoma","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10824","display_name":"Image Retrieval and Classification Techniques","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/thymic-epithelial-tumors","display_name":"thymic epithelial tumors","score":0.9769999980926514},{"id":"https://openalex.org/keywords/radiomics","display_name":"radiomics","score":0.9079999923706055},{"id":"https://openalex.org/keywords/computed-tomography","display_name":"computed tomography","score":0.8799999952316284},{"id":"https://openalex.org/keywords/histological-classification","display_name":"histological classification","score":0.6819999814033508},{"id":"https://openalex.org/keywords/tnm-stage","display_name":"TNM stage","score":0.7459999918937683},{"id":"https://openalex.org/keywords/myasthenia-gravis","display_name":"myasthenia gravis","score":0.9950000047683716},{"id":"https://openalex.org/keywords/imaging-biomarkers","display_name":"imaging biomarkers","score":0.8259999752044678},{"id":"https://openalex.org/keywords/who-histological-classification","display_name":"WHO histological classification","score":0.6650000214576721},{"id":"https://openalex.org/keywords/random-forest","display_name":"random forest","score":0.5099999904632568},{"id":"https://openalex.org/keywords/feature-selection","display_name":"feature selection","score":0.5350000262260437},{"id":"https://openalex.org/keywords/shap-feature-importance","display_name":"SHAP feature importance","score":0.6230000257492065}],"concepts":[{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.7623758316040039},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6738868355751038},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.6169242858886719},{"id":"https://openalex.org/C57742111","wikidata":"https://www.wikidata.org/wiki/Q7168","display_name":"Histology","level":2,"score":0.527185320854187},{"id":"https://openalex.org/C2778559731","wikidata":"https://www.wikidata.org/wiki/Q23808793","display_name":"Radiomics","level":2,"score":0.49079999327659607},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.43851280212402344},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.43504250049591064},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2939910888671875},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2677128314971924},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.07816147804260254},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006652","descriptor_name":"Histological Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009157","descriptor_name":"Myasthenia Gravis","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D009157","descriptor_name":"Myasthenia Gravis","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D009367","descriptor_name":"Neoplasm Staging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009375","descriptor_name":"Neoplasms, Glandular and Epithelial","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D009375","descriptor_name":"Neoplasms, Glandular and Epithelial","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D009375","descriptor_name":"Neoplasms, Glandular and Epithelial","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013953","descriptor_name":"Thymus Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D013953","descriptor_name":"Thymus Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D013953","descriptor_name":"Thymus Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1371/journal.pone.0261401","doi":"https://doi.org/10.1371/journal.pone.0261401","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0261401","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0261401&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},{"id":"pmid:34928978","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34928978","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PloS one","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8687592","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8687592/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS One","raw_type":"Text"},{"id":"pmh:oai:www.zora.uzh.ch:211843","doi":null,"is_oa":true,"landing_page_url":"https://www.zora.uzh.ch/id/eprint/211843/1/journal.pone.0261401.pdf","pdf_url":"https://www.zora.uzh.ch/id/eprint/211843/1/journal.pone.0261401.pdf","source":{"id":"https://openalex.org/S4306401281","display_name":"Zurich Open Repository and Archive (University of Zurich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I202697423","host_organization_name":"University of Zurich","host_organization_lineage":["https://openalex.org/I202697423"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Bl\u00fcthgen, Christian; Patella, Miriam; Euler, Andr\u00e9; Baessler, Bettina; Martini, Katharina; von Spiczak, Jochen; Schneiter, Didier; Opitz, Isabelle; Frauenfelder, Thomas (2021). Computed tomography radiomics for the prediction of thymic epithelial tumor histology, TNM stage and myasthenia gravis. PLoS ONE, 16(12):e0261401.","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:f2b048488f3f407dbcbdbf75abb9fe6a","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/f2b048488f3f407dbcbdbf75abb9fe6a","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS ONE, Vol 16, Iss 12, p e0261401 (2021)","raw_type":"article"},{"id":"pmh:oai:www.zora.uzh.ch:20.500.14742/190262","doi":null,"is_oa":true,"landing_page_url":"https://www.zora.uzh.ch/handle/20.500.14742/190262","pdf_url":null,"source":{"id":"https://openalex.org/S4306401281","display_name":"Zurich Open Repository and Archive (University of Zurich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I202697423","host_organization_name":"University of Zurich","host_organization_lineage":["https://openalex.org/I202697423"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bl\u00fcthgen, C., Patella, M., Euler, A., Baessler, B., Martini, K., von Spiczak, J., Schneiter, D., Opitz, I., & Frauenfelder, T. (2021). Computed tomography radiomics for the prediction of thymic epithelial tumor histology, TNM stage and myasthenia gravis. PLoS ONE, 16, e0261401. https://doi.org/10.1371/journal.pone.0261401","raw_type":"Journal Article"},{"id":"doi:10.5167/uzh-211843","doi":"https://doi.org/10.5167/uzh-211843","is_oa":true,"landing_page_url":"https://doi.org/10.5167/uzh-211843","pdf_url":null,"source":{"id":"https://openalex.org/S4306401281","display_name":"Zurich Open Repository and Archive (University of Zurich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I202697423","host_organization_name":"University of Zurich","host_organization_lineage":["https://openalex.org/I202697423"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"}],"best_oa_location":{"id":"doi:10.1371/journal.pone.0261401","doi":"https://doi.org/10.1371/journal.pone.0261401","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0261401","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0261401&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4200243233.pdf","grobid_xml":"https://content.openalex.org/works/W4200243233.grobid-xml"},"referenced_works_count":46,"referenced_works":["https://openalex.org/W1767875808","https://openalex.org/W1983404333","https://openalex.org/W2029785933","https://openalex.org/W2055957058","https://openalex.org/W2059426167","https://openalex.org/W2069998493","https://openalex.org/W2101234009","https://openalex.org/W2111568654","https://openalex.org/W2148143831","https://openalex.org/W2154290668","https://openalex.org/W2156665896","https://openalex.org/W2213414101","https://openalex.org/W2220624243","https://openalex.org/W2301520591","https://openalex.org/W2398056625","https://openalex.org/W2521200999","https://openalex.org/W2607616723","https://openalex.org/W2612457013","https://openalex.org/W2618851150","https://openalex.org/W2767128594","https://openalex.org/W2768734500","https://openalex.org/W2781552697","https://openalex.org/W2790526513","https://openalex.org/W2792832083","https://openalex.org/W2793070660","https://openalex.org/W2794293522","https://openalex.org/W2884380768","https://openalex.org/W2913754119","https://openalex.org/W2946868693","https://openalex.org/W2982714024","https://openalex.org/W2993944961","https://openalex.org/W2998789541","https://openalex.org/W2999615587","https://openalex.org/W3001768011","https://openalex.org/W3003257820","https://openalex.org/W3005956073","https://openalex.org/W3009268531","https://openalex.org/W3009755586","https://openalex.org/W3013522077","https://openalex.org/W3047506107","https://openalex.org/W3048802680","https://openalex.org/W3082775126","https://openalex.org/W3111272187","https://openalex.org/W3119494456","https://openalex.org/W3155205237","https://openalex.org/W3157824156"],"related_works":["https://openalex.org/W4411039845","https://openalex.org/W3009755586","https://openalex.org/W7125604679","https://openalex.org/W4408729596","https://openalex.org/W4408521867","https://openalex.org/W3134563761","https://openalex.org/W4414736360","https://openalex.org/W4389055084","https://openalex.org/W4403645537","https://openalex.org/W2993944961"],"abstract_inverted_index":{"OBJECTIVES:":[0],"To":[1],"evaluate":[2],"CT-derived":[3,214],"radiomics":[4],"for":[5,92,119,189,204,223],"machine":[6],"learning-based":[7],"classification":[8],"of":[9,23,168,182,207],"thymic":[10],"epithelial":[11],"tumor":[12],"(TET)":[13],"stage":[14,154,157,161],"(TNM":[15],"classification),":[16],"histology":[17,225],"(WHO":[18],"classification)":[19],"and":[20,57,99,196,226],"the":[21,34,169,183,205],"presence":[22],"myasthenia":[24],"gravis":[25],"(MG).":[26],"METHODS:":[27],"Patients":[28],"with":[29,42,80,138],"histologically":[30],"confirmed":[31],"TET":[32,120,141,148,224],"in":[33,152],"years":[35],"2000-2018":[36],"were":[37,50,55,60,65,76,85,108,121,165,175],"retrospectively":[38],"included,":[39],"excluding":[40],"patients":[41,116,128,170],"incompatible":[43],"imaging":[44,221],"or":[45,159],"other":[46],"tumors.":[47],"CT":[48],"scans":[49,64],"reformatted":[51],"uniformly,":[52],"gray":[53],"values":[54,107],"normalized":[56],"discretized.":[58],"Tumors":[59],"segmented":[61],"manually;":[62],"15":[63],"re-segmented":[66],"after":[67,177],"2":[68],"weeks":[69],"by":[70],"two":[71],"readers.":[72],"1316":[73],"radiomic":[74,215],"features":[75,174,216],"calculated":[77,109],"(pyRadiomics).":[78],"Features":[79],"low":[81],"intra-/inter-reader":[82,178],"agreement":[83],"(ICC<0.75)":[84],"excluded.":[86],"Repeated":[87],"nested":[88],"cross-validation":[89],"was":[90,187],"used":[91],"feature":[93,112],"selection":[94],"(Boruta":[95],"algorithm),":[96],"model":[97],"training,":[98],"evaluation":[100],"(out-of-fold":[101],"predictions).":[102],"Shapley":[103],"additive":[104],"explanation":[105],"(SHAP)":[106],"to":[110],"assess":[111],"importance.":[113],"RESULTS:":[114],"105":[115],"undergoing":[117],"surgery":[118],"identified.":[122],"After":[123],"applying":[124],"exclusion":[125],"criteria,":[126],"62":[127],"(28":[129],"female;":[130],"mean":[131],"age,":[132],"57\u00b114":[133],"years;":[134],"range,":[135],"22-82":[136],"years)":[137],"34":[139],"low-risk":[140],"(LRT;":[142],"WHO":[143,150],"types":[144],"A/AB/B1),":[145],"28":[146],"high-risk":[147],"(HRT;":[149],"B2/B3/C)":[151],"early":[153],"(49,":[155],"TNM":[156,163,197,227],"I-II)":[158],"advanced":[160],"(13,":[162],"III-IV)":[164],"included.":[166],"14(23%)":[167],"had":[171],"MG.":[172],"334(25%)":[173],"excluded":[176],"analysis.":[179],"Discriminatory":[180],"performance":[181],"random":[184],"forest":[185],"classifiers":[186],"good":[188],"histology(AUC,":[190],"87.6%;":[191],"95%":[192],"confidence":[193],"interval,":[194],"76.3-94.3)":[195],"stage(AUC,":[198],"83.8%;":[199],"95%CI,":[200,211],"66.9-93.4)":[201],"but":[202],"poor":[203],"prediction":[206],"MG":[208],"(AUC,":[209],"63.9%;":[210],"44.8-79.5).":[212],"CONCLUSIONS:":[213],"may":[217],"be":[218],"a":[219],"useful":[220],"biomarker":[222],"stage.":[228]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":11},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":5}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2021-12-31T00:00:00"}