{"id":"https://openalex.org/W4200217930","doi":"https://doi.org/10.1186/s12981-021-00424-1","title":"A systematic review and meta-analysis of HIV associated neurocognitive disorders (HAND) among people with HIV in Ethiopia","display_name":"A systematic review and meta-analysis of HIV associated neurocognitive disorders (HAND) among people with HIV in Ethiopia","publication_year":2021,"publication_date":"2021-12-01","ids":{"openalex":"https://openalex.org/W4200217930","doi":"https://doi.org/10.1186/s12981-021-00424-1","pmid":"https://pubmed.ncbi.nlm.nih.gov/34924002","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8684693"},"language":"en","primary_location":{"id":"doi:10.1186/s12981-021-00424-1","doi":"https://doi.org/10.1186/s12981-021-00424-1","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12981-021-00424-1","pdf_url":"https://aidsrestherapy.biomedcentral.com/counter/pdf/10.1186/s12981-021-00424-1","source":{"id":"https://openalex.org/S22960011","display_name":"AIDS Research and Therapy","issn_l":"1742-6405","issn":["1742-6405"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AIDS Research and Therapy","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://aidsrestherapy.biomedcentral.com/counter/pdf/10.1186/s12981-021-00424-1","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088869743","display_name":"Yosef Zenebe","orcid":"https://orcid.org/0000-0002-0138-6588","observed_orcids":["https://orcid.org/0000-0002-0138-6588"]},"institutions":[{"id":"https://openalex.org/I4210114501","display_name":"Wollo University","ror":"https://ror.org/01ktt8y73","country_code":"ET","type":"education","lineage":["https://openalex.org/I4210114501"]}],"countries":["ET"],"is_corresponding":true,"raw_author_name":"Yosef Zenebe","raw_affiliation_strings":["Department of Psychiatry, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia. yosef.zenebe79@gmail.com","Department of Psychiatry, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia"],"raw_orcid":"https://orcid.org/0000-0002-0138-6588","affiliations":[{"raw_affiliation_string":"Department of Psychiatry, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia. yosef.zenebe79@gmail.com","institution_ids":["https://openalex.org/I4210114501"]},{"raw_affiliation_string":"Department of Psychiatry, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia","institution_ids":["https://openalex.org/I4210114501"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090310103","display_name":"Baye Akele","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210114501","display_name":"Wollo University","ror":"https://ror.org/01ktt8y73","country_code":"ET","type":"education","lineage":["https://openalex.org/I4210114501"]}],"countries":["ET"],"is_corresponding":false,"raw_author_name":"Baye Akele","raw_affiliation_strings":["Department of Pharmacy, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia","institution_ids":["https://openalex.org/I4210114501"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108137149","display_name":"Mulugeta W Selassie","orcid":"https://orcid.org/0000-0002-3027-0162","observed_orcids":["https://orcid.org/0000-0002-3027-0162"]},"institutions":[{"id":"https://openalex.org/I4210114501","display_name":"Wollo University","ror":"https://ror.org/01ktt8y73","country_code":"ET","type":"education","lineage":["https://openalex.org/I4210114501"]}],"countries":["ET"],"is_corresponding":false,"raw_author_name":"Mulugeta W/Selassie","raw_affiliation_strings":["Department of Pediatrics and Child Health Nursing, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics and Child Health Nursing, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia","institution_ids":["https://openalex.org/I4210114501"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038879084","display_name":"Mogesie Necho","orcid":"https://orcid.org/0000-0003-0961-7835","observed_orcids":["https://orcid.org/0000-0003-0961-7835","https://orcid.org/0000-0003-2157-1147"]},"institutions":[{"id":"https://openalex.org/I4210114501","display_name":"Wollo University","ror":"https://ror.org/01ktt8y73","country_code":"ET","type":"education","lineage":["https://openalex.org/I4210114501"]}],"countries":["ET"],"is_corresponding":false,"raw_author_name":"Mogesie Necho","raw_affiliation_strings":["Department of Psychiatry, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia","institution_ids":["https://openalex.org/I4210114501"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5088869743"],"corresponding_institution_ids":["https://openalex.org/I4210114501"],"apc_list":{"value":2690,"currency":"USD","value_usd":2690},"apc_paid":{"value":2690,"currency":"USD","value_usd":2690},"fwci":0.3994,"has_fulltext":true,"cited_by_count":18,"citation_normalized_percentile":{"value":0.31195841,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":98},"biblio":{"volume":"18","issue":"1","first_page":"99","last_page":"99"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9164999723434448,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9164999723434448,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11655","display_name":"HIV-related health complications and treatments","score":0.03099999949336052,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.02329999953508377,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hiv-associated-neurocognitive-disorders","display_name":"HIV-associated neurocognitive disorders","score":0.9520000219345093},{"id":"https://openalex.org/keywords/hiv","display_name":"HIV","score":0.6190000176429749},{"id":"https://openalex.org/keywords/prevalence","display_name":"prevalence","score":0.8889999985694885},{"id":"https://openalex.org/keywords/ethiopia","display_name":"Ethiopia","score":0.9869999885559082},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.7020000219345093},{"id":"https://openalex.org/keywords/substance-use","display_name":"substance use","score":0.9169999957084656},{"id":"https://openalex.org/keywords/disease-stage","display_name":"disease stage","score":0.6930000185966492},{"id":"https://openalex.org/keywords/educational-attainment","display_name":"educational attainment","score":0.671999990940094},{"id":"https://openalex.org/keywords/regional-variation","display_name":"regional variation","score":0.5830000042915344},{"id":"https://openalex.org/keywords/health-education","display_name":"health education","score":0.5640000104904175},{"id":"https://openalex.org/keywords/screening","display_name":"screening","score":0.3619999885559082}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8104920983314514},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.7660225033760071},{"id":"https://openalex.org/C2780439572","wikidata":"https://www.wikidata.org/wiki/Q919364","display_name":"Publication bias","level":3,"score":0.7504363059997559},{"id":"https://openalex.org/C82605166","wikidata":"https://www.wikidata.org/wiki/Q967190","display_name":"Funnel plot","level":4,"score":0.7378635406494141},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.5167552828788757},{"id":"https://openalex.org/C129848803","wikidata":"https://www.wikidata.org/wiki/Q2564360","display_name":"Sample size determination","level":2,"score":0.5040323138237},{"id":"https://openalex.org/C2776478404","wikidata":"https://www.wikidata.org/wiki/Q1105187","display_name":"Cochrane Library","level":3,"score":0.5006272792816162},{"id":"https://openalex.org/C189708586","wikidata":"https://www.wikidata.org/wiki/Q1504425","display_name":"Systematic review","level":3,"score":0.44699984788894653},{"id":"https://openalex.org/C187960798","wikidata":"https://www.wikidata.org/wiki/Q7631152","display_name":"Subgroup analysis","level":3,"score":0.4415552020072937},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.37567248940467834},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.3626336455345154},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.3541189134120941},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.34351271390914917},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.3191191256046295},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1511540412902832},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005002","descriptor_name":"Ethiopia","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D015995","descriptor_name":"Prevalence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019965","descriptor_name":"Neurocognitive Disorders","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12981-021-00424-1","doi":"https://doi.org/10.1186/s12981-021-00424-1","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12981-021-00424-1","pdf_url":"https://aidsrestherapy.biomedcentral.com/counter/pdf/10.1186/s12981-021-00424-1","source":{"id":"https://openalex.org/S22960011","display_name":"AIDS Research and Therapy","issn_l":"1742-6405","issn":["1742-6405"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AIDS Research and Therapy","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8684693","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8684693","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AIDS Res Ther","raw_type":"Text"},{"id":"pmid:34924002","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34924002","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AIDS research and therapy","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:82f87a8a24274f5a90584f3f8e80a3d5","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/82f87a8a24274f5a90584f3f8e80a3d5","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"AIDS Research and Therapy, Vol 18, Iss 1, Pp 1-9 (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12981-021-00424-1","doi":"https://doi.org/10.1186/s12981-021-00424-1","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12981-021-00424-1","pdf_url":"https://aidsrestherapy.biomedcentral.com/counter/pdf/10.1186/s12981-021-00424-1","source":{"id":"https://openalex.org/S22960011","display_name":"AIDS Research and Therapy","issn_l":"1742-6405","issn":["1742-6405"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AIDS Research and Therapy","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"},{"display_name":"Meta-Analysis","id":"https://openalex.org/study-designs/meta-analysis"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4200217930.pdf","grobid_xml":"https://content.openalex.org/works/W4200217930.grobid-xml"},"referenced_works_count":33,"referenced_works":["https://openalex.org/W590228970","https://openalex.org/W1963537210","https://openalex.org/W1988634235","https://openalex.org/W2007528776","https://openalex.org/W2013110804","https://openalex.org/W2022027990","https://openalex.org/W2023836119","https://openalex.org/W2049863380","https://openalex.org/W2070898932","https://openalex.org/W2077946653","https://openalex.org/W2107415727","https://openalex.org/W2109887283","https://openalex.org/W2115118763","https://openalex.org/W2123212048","https://openalex.org/W2125435699","https://openalex.org/W2142102457","https://openalex.org/W2163168008","https://openalex.org/W2168428585","https://openalex.org/W2295774726","https://openalex.org/W2299269609","https://openalex.org/W2311070577","https://openalex.org/W2539890975","https://openalex.org/W2576440140","https://openalex.org/W2587696133","https://openalex.org/W2588681363","https://openalex.org/W2920951661","https://openalex.org/W2921902033","https://openalex.org/W3083014605","https://openalex.org/W3092401758","https://openalex.org/W3098739152","https://openalex.org/W3155979730","https://openalex.org/W3190282736","https://openalex.org/W4239165823"],"related_works":["https://openalex.org/W3139027552","https://openalex.org/W4281763265","https://openalex.org/W3204456519","https://openalex.org/W4376141626","https://openalex.org/W3083014605","https://openalex.org/W4210588300","https://openalex.org/W3030016455","https://openalex.org/W3108739218","https://openalex.org/W2539890975","https://openalex.org/W2007728565"],"abstract_inverted_index":{"BACKGROUND:":[0],"Ethiopia,":[1,275],"being":[2],"in":[3,39,60,75,94,159,186,195,199,211,260,274,297,313],"the":[4,13,24,51,71,79,90,112,116,143,160,165,181,187,212,261,269,285,292],"Sub":[5],"Saharan":[6],"region":[7],"of":[8,12,19,23,27,54,73,92,115,157,193,257,263,272,284,289,295,303,309],"Africa,":[9],"is":[10,35],"one":[11],"countries":[14],"with":[15,58,197,220,305],"a":[16],"substantial":[17],"burden":[18,26],"HIV":[20,28,59,198],"infection.":[21],"Because":[22],"high":[25],"and":[29,66,85,104,134,154,173,216,233,239,287,307],"poor":[30],"health":[31,310],"care":[32],"settings,":[33],"HAND":[34,55,74,93,194,296,316],"prevalent":[36],"as":[37],"demonstrated":[38],"various":[40],"cross-sectional":[41],"studies.":[42,123],"However,":[43,250],"no":[44,255],"review":[45,65],"has":[46],"been":[47],"conducted":[48],"to":[49,69,119],"report":[50],"consolidated":[52],"magnitude":[53],"among":[56],"people":[57,196,304],"Ethiopia.":[61,76,298],"Therefore,":[62],"this":[63,267],"systematic":[64],"meta-analysis":[67],"aimed":[68],"estimate":[70],"prevalence":[72,91,192,209,262,271],"METHODS:":[77],"Following":[78],"PRISMA":[80],"guidelines,":[81],"we":[82],"systematically":[83],"reviewed":[84],"meta-analyzed":[86],"studies":[87,118,139,178],"that":[88,179],"investigated":[89],"Ethiopia":[95,200],"from":[96],"PubMed,":[97],"Google":[98],"Scholar,":[99],"Science":[100],"Direct,":[101],"HINARI,":[102],"EMBASE,":[103],"Cochrane":[105],"library":[106],"databases.":[107],"We":[108],"also":[109],"looked":[110],"at":[111],"reference":[113],"lists":[114],"included":[117,185],"include":[120],"other":[121],"relevant":[122],"Subgroup":[124],"analysis":[125],"was":[126,140,149,201,248,276],"performed":[127],"based":[128],"on":[129,315],"publication":[130,147,258],"year,":[131],"study":[132],"location,":[133],"sample":[135],"size.":[136],"Heterogeneity":[137],"across":[138],"evaluated":[141],"using":[142,151],"I2":[144],"test.":[145],"Potential":[146],"bias":[148,259],"assessed":[150],"Egger's":[152,251],"test":[153],"visual":[155],"inspection":[156],"symmetry":[158],"funnel":[161,246],"plots.":[162],"RESULTS:":[163],"In":[164,266],"present":[166],"meta-analysis,":[167,268],"627":[168],"articles":[169],"were":[170,184,291],"initially":[171],"identified":[172],"evaluated.":[174],"Of":[175],"these,":[176],"8":[177],"met":[180],"inclusion":[182],"criteria":[183],"final":[188],"analysis.":[189],"The":[190,207],"pooled":[191,270],"39.15%":[202],"(95%":[203,222,235,242],"CI":[204,223,236,243],"29.36,":[205],"48.94).":[206],"highest":[208],"observed":[210],"Southern":[213],"Nations,":[214],"Nationalities,":[215],"Peoples'":[217],"Region":[218],"(SNNPR)":[219],"53.20%":[221],"25.96,":[224],"80.44)":[225],"followed":[226],"by":[227],"others":[228],"34.87%":[229],"(Tigray,":[230],"Addis":[231],"Ababa,":[232],"Oromia)":[234],"33.49,":[237],"36.24)":[238],"Amhara":[240],"34.07%":[241],"25.39,":[244],"42.74).The":[245],"plot":[247],"asymmetrical.":[249],"regression":[252],"tests":[253],"provided":[254],"evidence":[256],"HAND.":[264],"CONCLUSION:":[265],"HAND,":[273],"high.":[277],"Older":[278],"age,":[279],"substance":[280],"use,":[281],"advanced":[282],"stages":[283],"disease,":[286],"lack":[288],"education":[290],"main":[293],"determinants":[294],"Health":[299],"education,":[300],"early":[301],"screening":[302],"HIV,":[306],"training":[308],"professionals":[311],"working":[312],"hospitals":[314],"are":[317],"highly":[318],"recommended.":[319]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2021-12-31T00:00:00"}