{"id":"https://openalex.org/W4200166323","doi":"https://doi.org/10.2147/ijgm.s345345","title":"Fetal Nucleated Red Blood Cells Preferable Than Cell-Free Fetal DNA for Early Determination of Gender Among Invasive and Non-Invasive Source Using Novel Four Genes Multiplex PCR","display_name":"Fetal Nucleated Red Blood Cells Preferable Than Cell-Free Fetal DNA for Early Determination of Gender Among Invasive and Non-Invasive Source Using Novel Four Genes Multiplex PCR","publication_year":2021,"publication_date":"2021-12-01","ids":{"openalex":"https://openalex.org/W4200166323","doi":"https://doi.org/10.2147/ijgm.s345345","pmid":"https://pubmed.ncbi.nlm.nih.gov/34938099"},"language":"en","primary_location":{"id":"doi:10.2147/ijgm.s345345","doi":"https://doi.org/10.2147/ijgm.s345345","is_oa":true,"landing_page_url":"https://doi.org/10.2147/ijgm.s345345","pdf_url":"https://www.dovepress.com/getfile.php?fileID=76686","source":{"id":"https://openalex.org/S123199335","display_name":"International Journal of General Medicine","issn_l":"1178-7074","issn":["1178-7074"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","doyens","norway-1"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of General Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.dovepress.com/getfile.php?fileID=76686","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007698994","display_name":"Norah Fahad Alhur","orcid":"https://orcid.org/0000-0002-6165-4812","observed_orcids":["https://orcid.org/0000-0002-6165-4812"]},"institutions":[{"id":"https://openalex.org/I28022161","display_name":"King Saud University","ror":"https://ror.org/02f81g417","country_code":"SA","type":"education","lineage":["https://openalex.org/I28022161"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Norah F Alhur","raw_affiliation_strings":["College of Science, Zoology Department, King Saud University, Riyadh, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Science, Zoology Department, King Saud University, Riyadh, Saudi Arabia","institution_ids":["https://openalex.org/I28022161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112858136","display_name":"Nourah Hasan Al Qahtani","orcid":"https://orcid.org/0000-0003-1166-0541","observed_orcids":["https://orcid.org/0000-0003-1166-0541"]},"institutions":[{"id":"https://openalex.org/I76571253","display_name":"Imam Abdulrahman Bin Faisal University","ror":"https://ror.org/038cy8j79","country_code":"SA","type":"education","lineage":["https://openalex.org/I76571253"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Nourah H Al Qahtani","raw_affiliation_strings":["Obstetrics and Gynecology Department, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Obstetrics and Gynecology Department, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia","institution_ids":["https://openalex.org/I76571253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069459211","display_name":"Entissar S. AlSuhaibani","orcid":"https://orcid.org/0000-0003-2492-3136","observed_orcids":["https://orcid.org/0000-0003-2492-3136"]},"institutions":[{"id":"https://openalex.org/I28022161","display_name":"King Saud University","ror":"https://ror.org/02f81g417","country_code":"SA","type":"education","lineage":["https://openalex.org/I28022161"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Entissar S AlSuhaibani","raw_affiliation_strings":["College of Science, Zoology Department, King Saud University, Riyadh, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Science, Zoology Department, King Saud University, Riyadh, Saudi Arabia","institution_ids":["https://openalex.org/I28022161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061638311","display_name":"Eman S. Alsulmi","orcid":"https://orcid.org/0000-0001-9416-277X","observed_orcids":["https://orcid.org/0000-0001-9416-277X"]},"institutions":[{"id":"https://openalex.org/I76571253","display_name":"Imam Abdulrahman Bin Faisal University","ror":"https://ror.org/038cy8j79","country_code":"SA","type":"education","lineage":["https://openalex.org/I76571253"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Eman Alsulmi","raw_affiliation_strings":["Obstetrics and Gynecology Department, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Obstetrics and Gynecology Department, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia","institution_ids":["https://openalex.org/I76571253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060811563","display_name":"Noor Barak Almandil","orcid":"https://orcid.org/0000-0002-7049-3563","observed_orcids":["https://orcid.org/0000-0002-7049-3563"]},"institutions":[{"id":"https://openalex.org/I76571253","display_name":"Imam Abdulrahman Bin Faisal University","ror":"https://ror.org/038cy8j79","country_code":"SA","type":"education","lineage":["https://openalex.org/I76571253"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Noor B Almandil","raw_affiliation_strings":["Department of Clinical Pharmacy Research, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, Dammam, 31441, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacy Research, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, Dammam, 31441, Saudi Arabia","institution_ids":["https://openalex.org/I76571253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080906686","display_name":"Sayed AbdulAzeez","orcid":"https://orcid.org/0000-0002-9763-9446","observed_orcids":["https://orcid.org/0000-0002-9763-9446"]},"institutions":[{"id":"https://openalex.org/I76571253","display_name":"Imam Abdulrahman Bin Faisal University","ror":"https://ror.org/038cy8j79","country_code":"SA","type":"education","lineage":["https://openalex.org/I76571253"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Sayed AbdulAzeez","raw_affiliation_strings":["Department of Genetic Research, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia"],"raw_orcid":"https://orcid.org/0000-0002-9763-9446","affiliations":[{"raw_affiliation_string":"Department of Genetic Research, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia","institution_ids":["https://openalex.org/I76571253"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5009701292","display_name":"Jesu Francis Borgio","orcid":"https://orcid.org/0000-0001-7199-1540","observed_orcids":["https://orcid.org/0000-0001-7199-1540"]},"institutions":[{"id":"https://openalex.org/I76571253","display_name":"Imam Abdulrahman Bin Faisal University","ror":"https://ror.org/038cy8j79","country_code":"SA","type":"education","lineage":["https://openalex.org/I76571253"]}],"countries":["SA"],"is_corresponding":true,"raw_author_name":"J Francis Borgio","raw_affiliation_strings":["Department of Genetic Research, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia"],"raw_orcid":"https://orcid.org/0000-0001-7199-1540","affiliations":[{"raw_affiliation_string":"Department of Genetic Research, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia","institution_ids":["https://openalex.org/I76571253"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5009701292"],"corresponding_institution_ids":["https://openalex.org/I76571253"],"apc_list":{"value":2836,"currency":"USD","value_usd":2836},"apc_paid":{"value":2836,"currency":"USD","value_usd":2836},"fwci":0.4584,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.63929753,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"Volume 14","issue":null,"first_page":"9697","last_page":"9705"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10978","display_name":"Prenatal Screening and Diagnostics","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10978","display_name":"Prenatal Screening and Diagnostics","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10751","display_name":"Forensic and Genetic Research","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11970","display_name":"Molecular Biology Techniques and Applications","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prenatal-sex-determination","display_name":"fetal sex determination","score":0.9580000042915344},{"id":"https://openalex.org/keywords/erythroblasts","display_name":"erythroblasts","score":0.9079999923706055},{"id":"https://openalex.org/keywords/cell-free-fetal-dna","display_name":"cell-free fetal DNA","score":0.9940000176429749},{"id":"https://openalex.org/keywords/sry","display_name":"SRY","score":0.8489999771118164},{"id":"https://openalex.org/keywords/multiplex-pcr","display_name":"multiplex PCR","score":0.9449999928474426},{"id":"https://openalex.org/keywords/early-pregnancy","display_name":"early pregnancy","score":0.7549999952316284},{"id":"https://openalex.org/keywords/non-invasive-prenatal-testing","display_name":"non-invasive prenatal testing","score":0.890999972820282},{"id":"https://openalex.org/keywords/invasive-prenatal-diagnosis","display_name":"invasive prenatal diagnosis","score":0.6819999814033508},{"id":"https://openalex.org/keywords/umbilical-cord-blood","display_name":"umbilical cord blood","score":0.460999995470047},{"id":"https://openalex.org/keywords/maternal-plasma","display_name":"maternal plasma","score":0.5740000009536743},{"id":"https://openalex.org/keywords/x-linked-disorders","display_name":"X-linked disorders","score":0.4740000069141388}],"concepts":[{"id":"https://openalex.org/C2781188995","wikidata":"https://www.wikidata.org/wiki/Q6934982","display_name":"Multiplex","level":2,"score":0.7747270464897156},{"id":"https://openalex.org/C152110520","wikidata":"https://www.wikidata.org/wiki/Q14225730","display_name":"Cell-free fetal DNA","level":5,"score":0.7069854736328125},{"id":"https://openalex.org/C8185291","wikidata":"https://www.wikidata.org/wiki/Q2844457","display_name":"Amplicon","level":4,"score":0.6631456613540649},{"id":"https://openalex.org/C73456138","wikidata":"https://www.wikidata.org/wiki/Q409114","display_name":"Testis determining factor","level":4,"score":0.6095641255378723},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.6051365733146667},{"id":"https://openalex.org/C90583042","wikidata":"https://www.wikidata.org/wiki/Q1952456","display_name":"Multiplex polymerase chain reaction","level":4,"score":0.5434863567352295},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.5361957550048828},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.5039657950401306},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.46474382281303406},{"id":"https://openalex.org/C48023723","wikidata":"https://www.wikidata.org/wiki/Q856198","display_name":"Real-time polymerase chain reaction","level":3,"score":0.4435696005821228},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.415606290102005},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4097553491592407},{"id":"https://openalex.org/C49105822","wikidata":"https://www.wikidata.org/wiki/Q176996","display_name":"Polymerase chain reaction","level":3,"score":0.39920833706855774},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.39643460512161255},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.33790940046310425},{"id":"https://openalex.org/C2778258057","wikidata":"https://www.wikidata.org/wiki/Q1136569","display_name":"Prenatal diagnosis","level":4,"score":0.2514866590499878},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.24706804752349854},{"id":"https://openalex.org/C2780246931","wikidata":"https://www.wikidata.org/wiki/Q202771","display_name":"Y chromosome","level":3,"score":0.1636810600757599},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.09977304935455322}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.2147/ijgm.s345345","doi":"https://doi.org/10.2147/ijgm.s345345","is_oa":true,"landing_page_url":"https://doi.org/10.2147/ijgm.s345345","pdf_url":"https://www.dovepress.com/getfile.php?fileID=76686","source":{"id":"https://openalex.org/S123199335","display_name":"International Journal of General Medicine","issn_l":"1178-7074","issn":["1178-7074"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","doyens","norway-1"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of General Medicine","raw_type":"journal-article"},{"id":"pmid:34938099","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34938099","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of general medicine","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8687708","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8687708","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Int J Gen Med","raw_type":"Text"},{"id":"pmh:oai:dovepress.com/71400","doi":null,"is_oa":true,"landing_page_url":"https://www.dovepress.com/fetal-nucleated-red-blood-cells-preferable-than-cell-free-fetal-dna-fo-peer-reviewed-fulltext-article-IJGM","pdf_url":null,"source":{"id":"https://openalex.org/S4306401012","display_name":"Dove Medical Press (Taylor and Francis Group)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.2147/ijgm.s345345","doi":"https://doi.org/10.2147/ijgm.s345345","is_oa":true,"landing_page_url":"https://doi.org/10.2147/ijgm.s345345","pdf_url":"https://www.dovepress.com/getfile.php?fileID=76686","source":{"id":"https://openalex.org/S123199335","display_name":"International Journal of General Medicine","issn_l":"1178-7074","issn":["1178-7074"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","doyens","norway-1"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of General Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.4300000071525574,"display_name":"Peace, justice, and strong institutions","id":"https://metadata.un.org/sdg/16"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320328818","display_name":"Imam Abdulrahman Bin Faisal University","ror":null},{"id":"https://openalex.org/F4320336291","display_name":"Institute for Research and Medical Consultations, Imam Abdulrahman Bin Faisal University","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4200166323.pdf","grobid_xml":"https://content.openalex.org/works/W4200166323.grobid-xml"},"referenced_works_count":26,"referenced_works":["https://openalex.org/W906205929","https://openalex.org/W1963601387","https://openalex.org/W1985217644","https://openalex.org/W2046049047","https://openalex.org/W2062464354","https://openalex.org/W2074685898","https://openalex.org/W2135354716","https://openalex.org/W2145725346","https://openalex.org/W2166787818","https://openalex.org/W2170157345","https://openalex.org/W2177564016","https://openalex.org/W2190336360","https://openalex.org/W2489776031","https://openalex.org/W2782696655","https://openalex.org/W2809041861","https://openalex.org/W2887554272","https://openalex.org/W2944052704","https://openalex.org/W2951495475","https://openalex.org/W2957499607","https://openalex.org/W2989963329","https://openalex.org/W3035546154","https://openalex.org/W3037585989","https://openalex.org/W3038251895","https://openalex.org/W3088101907","https://openalex.org/W3112820885","https://openalex.org/W3190863439"],"related_works":["https://openalex.org/W2351342012","https://openalex.org/W1991752390","https://openalex.org/W4211021816","https://openalex.org/W2360792334","https://openalex.org/W2033567713","https://openalex.org/W2016890324","https://openalex.org/W1990638647","https://openalex.org/W2209796441","https://openalex.org/W2157677993","https://openalex.org/W2899937600"],"abstract_inverted_index":{"Background:":[0],"Deoxyribonucleic":[1],"acid":[2],"from":[3,70,78,88,103,133,184,230,266,300],"invasive,":[4,323],"non-invasive":[5],"and":[6,23,51,55,74,82,85,100,109,117,150,194,243,247,289,291],"9th":[7,79],"week":[8,80],"embryo":[9,81],"can":[10,195,250,272],"be":[11,128,251],"a":[12,129,285],"resource":[13],"for":[14,115,139,174,181,217,232,258,276,303],"the":[15,38,146,154,197,218,308],"determination":[16],"of":[17,30,145,158,161,187,238,256,270,297,310],"fetal":[18,65,76,86,188,228,261,264,298,327],"sex":[19,183,198],"using":[20,199,263],"highly":[21,191],"sensitive":[22],"specific":[24,46,155],"multiplex":[25,42,149,177,222,245],"PCR.":[26],"Methods:":[27],"A":[28],"total":[29],"402":[31],"DNA":[32,77,87,102,189,229,265,299],"samples":[33],"were":[34],"used":[35,114],"to":[36,274,306],"test":[37],"newly":[39],"developed":[40,241],"novel":[41,242],"PCR":[43,178,223,246],"including":[44,190],"male":[45,116,140,321],"(3":[47],"genes:":[48],"SRY,":[49],"DAZ2":[50],"TSPY1":[52],")":[53],"Y-biomarkers":[54,136,163],"internal":[56],"control,":[57],"ACTB":[58],".":[59],"The":[60,121,176,221,240],"study":[61,122],"isolated":[62],"cffDNA":[63,193],"(Cell-free":[64],"DNA;":[66],"n":[67,96],"=":[68,97,107,112],"73)":[69],"mother\u2019s":[71],"plasma,":[72],"serum":[73],"urine,":[75],"cord":[83],"blood,":[84],"CD71":[89],"+ve":[90],"nucleated":[91],"red":[92],"blood":[93,110],"cells":[94,105],"(fNRBC;":[95],"73).":[98],"Paternal":[99],"maternal":[101],"buccal":[104],"(n":[106,111],"20)":[108],"232)":[113],"female":[118],"confirmation.":[119],"Results:":[120],"observed":[123],"that":[124],"SRY":[125],"alone":[126],"cannot":[127],"suitable":[130,180],"Y-biomarker.":[131],"Confirmation":[132],"any":[134],"two":[135,159],"is":[137,171,179],"mandatory":[138],"fetus":[141],"identification.":[142],"Direct":[143],"sequencing":[144],"gel":[147],"eluted":[148],"single":[151,165],"amplicons":[152],"confirmed":[153],"sequences.":[156],"Presence":[157],"out":[160],"3":[162],"OR":[164],"Y-biomarker":[166],"with":[167],">":[168],"1,000,000":[169],"intensity":[170],"considered":[172],"positive":[173],"male.":[175],"determining":[182,259],"all":[185,254],"source":[186,296],"degraded":[192],"detect":[196],"0.5ng":[200],"DNA.":[201],"Individual":[202],"marker-based":[203],"real-time":[204],"qPCR":[205,249],"followed":[206],"by":[207],"combined":[208],"melt":[209,214],"curve":[210,215],"analysis":[211],"showed":[212],"distinguished":[213],"peaks":[216],"markers.":[219],"Conclusion:":[220],"achieved":[224],"100%":[225],"accuracy":[226],"on":[227],"fNRBC":[231,301,329],"early":[233,314],"determinations":[234],"(<":[235],"13":[236,316],"weeks)":[237,317],"gender.":[239],"simple":[244],"individual":[248],"adopted":[252],"in":[253,282,313],"types":[255],"laboratories":[257],"human":[260],"gender":[262,271,305],"fNRBC.":[267],"Early":[268],"identification":[269],"support":[273],"prepare":[275],"possible":[277],"X-linked":[278],"analysis,":[279],"reduce":[280,307],"anxiety":[281],"mother,":[283],"strengthen":[284],"bond":[286],"between":[287],"mother":[288],"fetus,":[290],"effective":[292],"decision":[293],"making.":[294],"Non-invasive":[295],"preferred":[302],"identifying":[304],"risk":[309],"invasive":[311],"procedures":[312],"(8\u2013":[315],"pregnancy.":[318],"Keywords:":[319],"cffDNA,":[320],"PCR,":[322],"non-invasive,":[324],"Y":[325],"biomarkers,":[326],"gender,":[328]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1}],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2025-10-10T00:00:00"}