{"id":"https://openalex.org/W413534877","doi":null,"title":"[Recent advances in allergic rhinitis].","display_name":"[Recent advances in allergic rhinitis].","publication_year":2015,"publication_date":"2015-02-01","ids":{"openalex":"https://openalex.org/W413534877","mag":"413534877","pmid":"https://pubmed.ncbi.nlm.nih.gov/26012287"},"language":"zh","primary_location":{"id":"pmid:26012287","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26012287","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037766997","display_name":"Mei-Jun Liang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Meijun Liang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003089944","display_name":"Rui Dan Xu","orcid":"https://orcid.org/0000-0002-2065-6117","observed_orcids":["https://orcid.org/0000-0002-2065-6117"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rui Xu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5068541979","display_name":"Geng Xu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Geng Xu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.0479,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.76214792,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"29","issue":"3","first_page":"202","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10634","display_name":"Food Allergy and Anaphylaxis Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/allergic-rhinitis","display_name":"allergic rhinitis","score":1.0},{"id":"https://openalex.org/keywords/local-allergic-rhinitis","display_name":"local allergic rhinitis","score":0.8529999852180481},{"id":"https://openalex.org/keywords/immunoglobulin-e","display_name":"immunoglobulin E","score":0.7390000224113464},{"id":"https://openalex.org/keywords/allergen-identification","display_name":"allergen identification","score":0.597000002861023},{"id":"https://openalex.org/keywords/rhinovirus","display_name":"rhinovirus","score":0.37299999594688416},{"id":"https://openalex.org/keywords/leukotriene-receptor-antagonists","display_name":"leukotriene receptor antagonists","score":0.8040000200271606},{"id":"https://openalex.org/keywords/montelukast","display_name":"montelukast","score":0.9950000047683716},{"id":"https://openalex.org/keywords/allergen-immunotherapy","display_name":"allergen immunotherapy","score":0.972000002861023},{"id":"https://openalex.org/keywords/allergen-avoidance","display_name":"allergen avoidance","score":0.8610000014305115},{"id":"https://openalex.org/keywords/drug-therapy","display_name":"pharmacotherapy","score":0.8169999718666077},{"id":"https://openalex.org/keywords/asthma-progression","display_name":"asthma progression","score":0.6660000085830688},{"id":"https://openalex.org/keywords/aria-guidelines","display_name":"ARIA guidelines","score":0.7929999828338623},{"id":"https://openalex.org/keywords/pathophysiology","display_name":"pathophysiology","score":0.8299999833106995}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8646725416183472},{"id":"https://openalex.org/C2779787640","wikidata":"https://www.wikidata.org/wiki/Q1641412","display_name":"Allergen immunotherapy","level":4,"score":0.7085710763931274},{"id":"https://openalex.org/C2779699568","wikidata":"https://www.wikidata.org/wiki/Q1115038","display_name":"rhinorrhea","level":2,"score":0.650884747505188},{"id":"https://openalex.org/C2776322731","wikidata":"https://www.wikidata.org/wiki/Q417767","display_name":"Montelukast","level":3,"score":0.5983997583389282},{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.5923905372619629},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5458245277404785},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.5326774716377258},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5306685566902161},{"id":"https://openalex.org/C2777844070","wikidata":"https://www.wikidata.org/wiki/Q3245488","display_name":"Nasal congestion","level":3,"score":0.49337664246559143},{"id":"https://openalex.org/C2777697326","wikidata":"https://www.wikidata.org/wiki/Q757678","display_name":"Atopy","level":3,"score":0.4804536700248718},{"id":"https://openalex.org/C2779779143","wikidata":"https://www.wikidata.org/wiki/Q3493547","display_name":"Desensitization (medicine)","level":3,"score":0.478620707988739},{"id":"https://openalex.org/C2780212800","wikidata":"https://www.wikidata.org/wiki/Q20708039","display_name":"Leukotriene receptor","level":4,"score":0.4688348174095154},{"id":"https://openalex.org/C207480886","wikidata":"https://www.wikidata.org/wiki/Q42982","display_name":"Allergy","level":2,"score":0.4394381642341614},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.4295506477355957},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.34297847747802734},{"id":"https://openalex.org/C2780510475","wikidata":"https://www.wikidata.org/wiki/Q186752","display_name":"Allergen","level":3,"score":0.32366877794265747},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.17682480812072754},{"id":"https://openalex.org/C2778311950","wikidata":"https://www.wikidata.org/wiki/Q7363","display_name":"Nose","level":2,"score":0.16851115226745605},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.16154524683952332},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.08263987302780151},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.06728652119636536}],"mesh":[{"descriptor_ui":"D000085","descriptor_name":"Acetates","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000485","descriptor_name":"Allergens","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000893","descriptor_name":"Anti-Inflammatory Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D001249","descriptor_name":"Asthma","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003521","descriptor_name":"Cyclopropanes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006969","descriptor_name":"Hypersensitivity, Immediate","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D006969","descriptor_name":"Hypersensitivity, Immediate","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D007073","descriptor_name":"Immunoglobulin E","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D007167","descriptor_name":"Immunotherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D011804","descriptor_name":"Quinolines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D013440","descriptor_name":"Sulfides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015995","descriptor_name":"Prevalence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020024","descriptor_name":"Leukotriene Antagonists","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D065631","descriptor_name":"Rhinitis, Allergic","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D065631","descriptor_name":"Rhinitis, Allergic","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D065631","descriptor_name":"Rhinitis, Allergic","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:26012287","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26012287","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery","raw_type":"Journal Article"},{"id":"mag:413534877","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26012287","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7150052000","https://openalex.org/W2018391933","https://openalex.org/W4382814931","https://openalex.org/W7168426061","https://openalex.org/W4393328050","https://openalex.org/W2003099988","https://openalex.org/W4239587674","https://openalex.org/W4407112118","https://openalex.org/W4213126890","https://openalex.org/W4399387180"],"abstract_inverted_index":{"Allergic":[0],"rhinitis":[1,89],"(AR)":[2],"clinically":[3],"expressed":[4],"by":[5,21,60],"sneezing,":[6],"rhinorrhea,":[7],"nasal":[8],"itching":[9],"and":[10,35,51,66,100,135,176,202,227,247],"congestion":[11],"is":[12,19,64,112],"an":[13,62,217,240],"allergen-driven":[14],"mucosal":[15],"inflammatory":[16],"disease":[17,174],"which":[18,61,71],"modulated":[20],"immunoglobulin":[22],"E.":[23],"Epidemiological":[24],"studies":[25,84],"have":[26,85,108],"indicated":[27],"that":[28,43,91],"prevalence":[29],"of":[30,57,69,78,98,127,159,210,213,229,234,249],"AR":[31,74,79,99,128],"continues":[32],"to":[33,172,180,238],"increase,":[34],"it":[36],"has":[37,80,140,163],"been":[38,170],"a":[39,45,101,113,152],"worldwide":[40],"health":[41],"problem":[42],"places":[44],"significant":[46],"healthcare":[47],"burden":[48],"on":[49,205,224,243],"individuals":[50],"society.":[52],"Given":[53],"the":[54,58,67,76,157,198,225,244],"evolving":[55],"understanding":[56],"process":[59],"allergen":[63],"recognized":[65],"roles":[68],"mediators":[70],"account":[72],"for":[73,105],"progress,":[75],"pathogenesis":[77],"become":[81],"clearer.":[82],"Current":[83],"demonstrated":[86],"local":[87,109],"allergic":[88,110],"(LAR)":[90],"patients":[92,117],"with":[93,119,193],"both":[94],"sug-":[95],"gestive":[96],"symptoms":[97],"negative":[102],"diagnostic":[103],"test":[104],"atopy":[106],"may":[107,150],"inflammation":[111],"prevalent":[114],"entity":[115],"in":[116,156,191],"evaluated":[118],"rhinitis,":[120],"but":[121,168],"further":[122],"research":[123],"remains":[124],"needed.":[125],"Management":[126],"includes":[129],"aller-":[130],"gen":[131],"avoidance,":[132],"pharmacological":[133],"treatment":[134,158,212,219],"allergen-specific":[136],"immunotherapy.":[137],"Recently":[138],"montelukast":[139],"exhibited":[141],"previously":[142],"undocumented":[143],"anti-inflammatory":[144],"properties,":[145],"leukotriene":[146],"receptor":[147],"antagonists":[148],"therefore":[149],"serve":[151],"more":[153],"important":[154],"role":[155],"AR.":[160,194,214,250],"Not":[161],"only":[162],"immunotherapy":[164,183],"proved":[165],"its":[166,203],"efficacy,":[167],"also":[169],"able":[171],"alter":[173],"course":[175],"thereby":[177],"mitigate":[178],"progression":[179],"asthma.":[181],"Thus":[182],"can":[184],"be":[185,222],"initiated":[186],"while":[187],"receiving":[188],"pharmacotherapy,":[189],"especially":[190],"children":[192],"As":[195],"clinical":[196],"guidelines,":[197],"ARIA":[199],"(Allergic":[200],"Rhinitis":[201],"Impact":[204],"Asthma)":[206],"provides":[207],"basic":[208],"principles":[209],"effective":[211],"Besides,":[215],"choosing":[216],"appropriate":[218],"strategy":[220],"should":[221],"based":[223],"severity":[226],"chronicity":[228],"patient's":[230],"symptom.":[231],"The":[232],"aim":[233],"this":[235],"review":[236],"was":[237],"provide":[239],"update":[241],"mainly":[242],"pathophysiology,":[245],"epidemiology,":[246],"management":[248]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}